BacMap

Definition	Exiguobacterium sp. AT1b, complete genome.
Accession	NC_012673
Length	2,999,895

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The map label for this gene is yeaE [H]

Identifier: 229916689

GI number: 229916689

Start: 908994

End: 909887

Strand: Reverse

Name: yeaE [H]

Synonym: EAT1b_0962

Alternate gene names: 229916689

Gene position: 909887-908994 (Counterclockwise)

Preceding gene: 229916690

Following gene: 229916688

Centisome position: 30.33

GC content: 54.81

Gene sequence:

>894_bases
ATGAATCAACGACTACCACATTCTTTATTACTCGCAGCTTTGAAACAAAACGTCGTCGAATTGAAAGATGGCCGCGAGAT
GCGCGCACTCGGGCAAGGGACGTGGCGTATGGGGGAAGACAAATCGAAGCATGATGCCGAGGTCGAAGCGCTTCGGACAG
GACTCGACTGCGGACTTCATGTTATCGATACGGCGGAAATGTACGGGGAAGGGGAGTCTGAGAAGTTGGTCGGAGAAGCC
ATTCAAGACCGACGTGAGGACGTCTTCCTCGTCTCGAAAGTGTATCCATACAATGCGTATGGCGACAAACTCGTCAGCGC
ATGTGATGCGTCGCTCGAGCGACTCGGGACGGACTACCTGGATCTTTACTTACTCCATTGGCGAGGCGATGCCCCGCTCG
AGGAAACGATTCAAGGGATGGAACAGCTTAAAGCGGACGGGAAGATTCGGGCATGGGGGGTCTCGAACTTCGATGTGGAC
GACATGGAAGAATTGCTGTCGCTACCGAATGGAGACAAGTGCGCGGTCAATCAAGTGCTCTATCATCTTGGCAGTCGCGG
GATTGAGTACGACCTCCTTCCTTATCTAGAAGAACAAGGCATTCCCGTCATGGCGTACGCGCCGCTCGCCGAGGGAAGTG
ACGTGAAAAAAGACGTCTTCGAAAACGAGACGGTCAATCGGATCGCAGAGGCGTATAGTGCCTCCGTCGCACAAATCTTG
CTTGCCTGGACGATCCGGAGCGGACACGTCATCGCCATCCCGAAAGCCGGGCAGGCTGAGCATGTCGAAGAGAATGCGGC
GGCGCTCTTGCTCGACATGAGTGAGGAAGATTTCGCGGCGCTCGATGAGGCGTTCCCTCCACCGACGACGAAACAACCGC
TAGATGTCATTTGA

Upstream 100 bases:

>100_bases
ACAATGTGAAGCGAATCGAACAAGTCGACAAGCCGAAGTTTGACCCCGTCTTCGGGACGACGGGCCCACTACATGAGGAA
TGGACAAAGGAGGAAACGTT

Downstream 100 bases:

>100_bases
CGATGTGAACTGGGCCAAACAAAGGTCCAGTTTTTCTTCTGTGGAAATCGATTGTCCTTTACAGGTTGCGGGTAAATATA
GGAAGGACTTGCTTGTGTAG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNQRLPHSLLLAALKQNVVELKDGREMRALGQGTWRMGEDKSKHDAEVEALRTGLDCGLHVIDTAEMYGEGESEKLVGEA
IQDRREDVFLVSKVYPYNAYGDKLVSACDASLERLGTDYLDLYLLHWRGDAPLEETIQGMEQLKADGKIRAWGVSNFDVD
DMEELLSLPNGDKCAVNQVLYHLGSRGIEYDLLPYLEEQGIPVMAYAPLAEGSDVKKDVFENETVNRIAEAYSASVAQIL
LAWTIRSGHVIAIPKAGQAEHVEENAAALLLDMSEEDFAALDEAFPPPTTKQPLDVI

Sequences:

>Translated_297_residues
MNQRLPHSLLLAALKQNVVELKDGREMRALGQGTWRMGEDKSKHDAEVEALRTGLDCGLHVIDTAEMYGEGESEKLVGEA
IQDRREDVFLVSKVYPYNAYGDKLVSACDASLERLGTDYLDLYLLHWRGDAPLEETIQGMEQLKADGKIRAWGVSNFDVD
DMEELLSLPNGDKCAVNQVLYHLGSRGIEYDLLPYLEEQGIPVMAYAPLAEGSDVKKDVFENETVNRIAEAYSASVAQIL
LAWTIRSGHVIAIPKAGQAEHVEENAAALLLDMSEEDFAALDEAFPPPTTKQPLDVI
>Mature_297_residues
MNQRLPHSLLLAALKQNVVELKDGREMRALGQGTWRMGEDKSKHDAEVEALRTGLDCGLHVIDTAEMYGEGESEKLVGEA
IQDRREDVFLVSKVYPYNAYGDKLVSACDASLERLGTDYLDLYLLHWRGDAPLEETIQGMEQLKADGKIRAWGVSNFDVD
DMEELLSLPNGDKCAVNQVLYHLGSRGIEYDLLPYLEEQGIPVMAYAPLAEGSDVKKDVFENETVNRIAEAYSASVAQIL
LAWTIRSGHVIAIPKAGQAEHVEENAAALLLDMSEEDFAALDEAFPPPTTKQPLDVI

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI223468663, Length=298, Percent_Identity=30.2013422818792, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI24497577, Length=299, Percent_Identity=29.4314381270903, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI5174391, Length=299, Percent_Identity=29.4314381270903, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI291291012, Length=266, Percent_Identity=29.6992481203008, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI93277124, Length=299, Percent_Identity=27.7591973244147, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI5174695, Length=298, Percent_Identity=26.1744966442953, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI4502049, Length=296, Percent_Identity=30.7432432432432, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI310109922, Length=284, Percent_Identity=29.5774647887324, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI300116273, Length=281, Percent_Identity=27.0462633451957, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI45446745, Length=304, Percent_Identity=28.9473684210526, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI4503285, Length=304, Percent_Identity=28.9473684210526, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI24497585, Length=302, Percent_Identity=27.8145695364238, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI310109920, Length=304, Percent_Identity=28.6184210526316, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI5453543, Length=304, Percent_Identity=28.2894736842105, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI24497583, Length=303, Percent_Identity=26.7326732673267, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI27436969, Length=299, Percent_Identity=24.7491638795987, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4504825, Length=299, Percent_Identity=24.7491638795987, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI223718702, Length=184, Percent_Identity=31.5217391304348, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI27436962, Length=211, Percent_Identity=26.0663507109005, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI27436964, Length=211, Percent_Identity=26.0663507109005, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI27436966, Length=211, Percent_Identity=26.0663507109005, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI41327764, Length=179, Percent_Identity=29.608938547486, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI41152114, Length=182, Percent_Identity=30.2197802197802, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI207028673, Length=122, Percent_Identity=38.5245901639344, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1788081, Length=284, Percent_Identity=55.2816901408451, Blast_Score=337, Evalue=7e-94,
Organism=Escherichia coli, GI1786400, Length=265, Percent_Identity=31.6981132075472, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788070, Length=311, Percent_Identity=29.5819935691318, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082198, Length=254, Percent_Identity=29.9212598425197, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87081735, Length=295, Percent_Identity=28.135593220339, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1789375, Length=312, Percent_Identity=25, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI48994888, Length=295, Percent_Identity=27.7966101694915, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787674, Length=273, Percent_Identity=24.9084249084249, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789199, Length=257, Percent_Identity=29.5719844357977, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71998625, Length=277, Percent_Identity=35.0180505415162, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17552492, Length=272, Percent_Identity=30.1470588235294, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17561300, Length=275, Percent_Identity=29.0909090909091, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17538386, Length=288, Percent_Identity=30.5555555555556, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17564128, Length=305, Percent_Identity=29.5081967213115, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17566692, Length=298, Percent_Identity=26.510067114094, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17561298, Length=285, Percent_Identity=29.4736842105263, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17550248, Length=297, Percent_Identity=26.2626262626263, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17537077, Length=297, Percent_Identity=29.2929292929293, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17537075, Length=297, Percent_Identity=29.6296296296296, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17537079, Length=303, Percent_Identity=25.0825082508251, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562292, Length=304, Percent_Identity=24.0131578947368, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324694, Length=298, Percent_Identity=28.1879194630872, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6320576, Length=321, Percent_Identity=27.7258566978193, Blast_Score=109, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320079, Length=292, Percent_Identity=29.1095890410959, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322556, Length=293, Percent_Identity=26.2798634812287, Blast_Score=93, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6319625, Length=275, Percent_Identity=28, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI20129731, Length=296, Percent_Identity=29.3918918918919, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24662789, Length=298, Percent_Identity=28.5234899328859, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI45553081, Length=290, Percent_Identity=29.3103448275862, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24663317, Length=299, Percent_Identity=28.4280936454849, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24657054, Length=295, Percent_Identity=29.1525423728814, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI21356425, Length=300, Percent_Identity=27.6666666666667, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24644950, Length=310, Percent_Identity=27.741935483871, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281366140, Length=253, Percent_Identity=28.0632411067194, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646155, Length=182, Percent_Identity=29.6703296703297, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24662781, Length=290, Percent_Identity=25.5172413793103, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 32889; Mature: 32889

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQRLPHSLLLAALKQNVVELKDGREMRALGQGTWRMGEDKSKHDAEVEALRTGLDCGLH
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCEE
VIDTAEMYGEGESEKLVGEAIQDRREDVFLVSKVYPYNAYGDKLVSACDASLERLGTDYL
EEEHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHH
DLYLLHWRGDAPLEETIQGMEQLKADGKIRAWGVSNFDVDDMEELLSLPNGDKCAVNQVL
EEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHH
YHLGSRGIEYDLLPYLEEQGIPVMAYAPLAEGSDVKKDVFENETVNRIAEAYSASVAQIL
HHHCCCCCCCCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LAWTIRSGHVIAIPKAGQAEHVEENAAALLLDMSEEDFAALDEAFPPPTTKQPLDVI
HHHEECCCCEEEECCCCCHHHHHHCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MNQRLPHSLLLAALKQNVVELKDGREMRALGQGTWRMGEDKSKHDAEVEALRTGLDCGLH
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCEE
VIDTAEMYGEGESEKLVGEAIQDRREDVFLVSKVYPYNAYGDKLVSACDASLERLGTDYL
EEEHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHH
DLYLLHWRGDAPLEETIQGMEQLKADGKIRAWGVSNFDVDDMEELLSLPNGDKCAVNQVL
EEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHH
YHLGSRGIEYDLLPYLEEQGIPVMAYAPLAEGSDVKKDVFENETVNRIAEAYSASVAQIL
HHHCCCCCCCCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LAWTIRSGHVIAIPKAGQAEHVEENAAALLLDMSEEDFAALDEAFPPPTTKQPLDVI
HHHEECCCCEEEECCCCCHHHHHHCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]