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The map label for this gene is tpiA [H]

Identifier: 229916590

GI number: 229916590

Start: 815857

End: 816609

Strand: Reverse

Name: tpiA [H]

Synonym: EAT1b_0862

Alternate gene names: 229916590

Gene position: 816609-815857 (Counterclockwise)

Preceding gene: 229916591

Following gene: 229916589

Centisome position: 27.22

GC content: 49.67

Gene sequence:

>753_bases
ATGCGTAAACCGATTATTGCAGGTAACTGGAAAATGAACAAAACACTCTCGGAAGCTGTTGCTTTCGTTGAGGAAGTAAA
AAACAACATCCCATCTACTGACAAAGTAGATGCAGCGATTGGTGCTCCAGCACTTTTCCTCGCACCGATGGTAGAAGCAG
CTAAAGGGTCAAACTTGAAGCTCGGTGCACAAAACATGTACGACAAAGATAGCGGTGCCTACACTGGCGAAATCAGCCCA
GCTATGATCGCTGACCTCGGCGTGACTTACGTCATCCTCGGTCACTCAGAACGTCGCGAGTACTTCGGCGAATCAGATGC
GTTCATCAACAGCAAAACGAAAAAAGCGTTCGAACACGGTCTTACGCCAATCGTTTGTGTCGGTGAAACACTCGAGGAGC
GCGAAGGCGACAAGTTCGAAGAAGTCATCAAAACACAAGTCGAAGGCGGCCTCGCTGACCTTTCTGCTGACCAAGTCAAA
CAACTCGTCATCGCGTATGAGCCAGTTTGGGCAATCGGTACAGGGAAATCAGCGGACGAAGCAGACGCGCAAAGCTCTTG
TAAATATGTTCGCGACGTGGTGAAAGGTCTTTACGGTGAAGACGTAGCGGCTGCAGTACGCATCCAGTACGGTGGATCTG
TAAAACCAGAGAACATCAAAGAGTATATGGCACAGGAAGACATCGACGGCGCACTCGTCGGCGGTGCTTCACTTGAAGCC
GCTTCGTTCCTCAAATTGTTGGAGGCGATTTAA

Upstream 100 bases:

>100_bases
CATCTCAACTGGTGGCGGCGCGTCACTCGAATTCATGGAAGGCAAAAAACTTCCAGGTGTCGAGGCGTTGAACGACAAGT
AATTTAGAGGAGGGTTATCG

Downstream 100 bases:

>100_bases
ATGGCTAGACCAGTCGCACTCATCATTTTAGATGGTTTCGGGATGCGTGACGAATCGTTCGGAAACGCAGTCATGGCTGC
GAACAAACCGAACTTCGATC

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MRKPIIAGNWKMNKTLSEAVAFVEEVKNNIPSTDKVDAAIGAPALFLAPMVEAAKGSNLKLGAQNMYDKDSGAYTGEISP
AMIADLGVTYVILGHSERREYFGESDAFINSKTKKAFEHGLTPIVCVGETLEEREGDKFEEVIKTQVEGGLADLSADQVK
QLVIAYEPVWAIGTGKSADEADAQSSCKYVRDVVKGLYGEDVAAAVRIQYGGSVKPENIKEYMAQEDIDGALVGGASLEA
ASFLKLLEAI

Sequences:

>Translated_250_residues
MRKPIIAGNWKMNKTLSEAVAFVEEVKNNIPSTDKVDAAIGAPALFLAPMVEAAKGSNLKLGAQNMYDKDSGAYTGEISP
AMIADLGVTYVILGHSERREYFGESDAFINSKTKKAFEHGLTPIVCVGETLEEREGDKFEEVIKTQVEGGLADLSADQVK
QLVIAYEPVWAIGTGKSADEADAQSSCKYVRDVVKGLYGEDVAAAVRIQYGGSVKPENIKEYMAQEDIDGALVGGASLEA
ASFLKLLEAI
>Mature_250_residues
MRKPIIAGNWKMNKTLSEAVAFVEEVKNNIPSTDKVDAAIGAPALFLAPMVEAAKGSNLKLGAQNMYDKDSGAYTGEISP
AMIADLGVTYVILGHSERREYFGESDAFINSKTKKAFEHGLTPIVCVGETLEEREGDKFEEVIKTQVEGGLADLSADQVK
QLVIAYEPVWAIGTGKSADEADAQSSCKYVRDVVKGLYGEDVAAAVRIQYGGSVKPENIKEYMAQEDIDGALVGGASLEA
ASFLKLLEAI

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=254, Percent_Identity=42.1259842519685, Blast_Score=176, Evalue=1e-44,
Organism=Homo sapiens, GI226529917, Length=254, Percent_Identity=42.1259842519685, Blast_Score=176, Evalue=2e-44,
Organism=Escherichia coli, GI1790353, Length=249, Percent_Identity=45.3815261044177, Blast_Score=208, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17536593, Length=251, Percent_Identity=45.4183266932271, Blast_Score=186, Evalue=9e-48,
Organism=Saccharomyces cerevisiae, GI6320255, Length=239, Percent_Identity=41.8410041841004, Blast_Score=170, Evalue=2e-43,
Organism=Drosophila melanogaster, GI28572008, Length=251, Percent_Identity=44.6215139442231, Blast_Score=188, Evalue=3e-48,
Organism=Drosophila melanogaster, GI28572006, Length=251, Percent_Identity=44.6215139442231, Blast_Score=188, Evalue=3e-48,
Organism=Drosophila melanogaster, GI28572004, Length=251, Percent_Identity=44.6215139442231, Blast_Score=188, Evalue=3e-48,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 26802; Mature: 26802

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKPIIAGNWKMNKTLSEAVAFVEEVKNNIPSTDKVDAAIGAPALFLAPMVEAAKGSNLK
CCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCEE
LGAQNMYDKDSGAYTGEISPAMIADLGVTYVILGHSERREYFGESDAFINSKTKKAFEHG
ECCCCCCCCCCCCEECCCCHHHHHHCCEEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHC
LTPIVCVGETLEEREGDKFEEVIKTQVEGGLADLSADQVKQLVIAYEPVWAIGTGKSADE
CCEEEECCCHHHHHCCHHHHHHHHHHHCCCHHCCCHHHHHHHHHHCCCEEEECCCCCCCH
ADAQSSCKYVRDVVKGLYGEDVAAAVRIQYGGSVKPENIKEYMAQEDIDGALVGGASLEA
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEECCCHHHH
ASFLKLLEAI
HHHHHHHHHC
>Mature Secondary Structure
MRKPIIAGNWKMNKTLSEAVAFVEEVKNNIPSTDKVDAAIGAPALFLAPMVEAAKGSNLK
CCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCEE
LGAQNMYDKDSGAYTGEISPAMIADLGVTYVILGHSERREYFGESDAFINSKTKKAFEHG
ECCCCCCCCCCCCEECCCCHHHHHHCCEEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHC
LTPIVCVGETLEEREGDKFEEVIKTQVEGGLADLSADQVKQLVIAYEPVWAIGTGKSADE
CCEEEECCCHHHHHCCHHHHHHHHHHHCCCHHCCCHHHHHHHHHHCCCEEEECCCCCCCH
ADAQSSCKYVRDVVKGLYGEDVAAAVRIQYGGSVKPENIKEYMAQEDIDGALVGGASLEA
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEECCCHHHH
ASFLKLLEAI
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA