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The map label for this gene is ezrA [H]

Identifier: 229916419

GI number: 229916419

Start: 642784

End: 644514

Strand: Reverse

Name: ezrA [H]

Synonym: EAT1b_0689

Alternate gene names: 229916419

Gene position: 644514-642784 (Counterclockwise)

Preceding gene: 229916422

Following gene: 229916418

Centisome position: 21.48

GC content: 45.98

Gene sequence:

>1731_bases
ATGGATTACGGAATTTATGGATTAATCATTGGAATCATCGTCGTCGTATTAGGCGGCATGTTGGGGAGTATGCTCATTCG
AAGGAATTTTTACCAAAAAATTGACGACTTGGATATGAGGAAACAAAGTGTGCTCAGTGCGAGCATACCCGTCGAACTCC
AGAAATTCAAACAGTGGCCGATGGAAGGGGAAACGAAAGAAAAGTTTGATCGTTGGCATCAATCTTGGGATGAGTTAGTA
AGTGTACATGCAGGTCAAATCGATGAAGCGCTGTACCGGGCTGAGGAAGACTTGGACAAATATCGTTTCATGAAAGTCAA
AGCTGACTTGAATGCGACTGAACAACTCATTGAAGAACTCGAGACGATGGTACACGCCATGCTCGATGAGATGGATGAAT
TTACGACACATCACACCTCGCTTATGGACATCGTGAAGCAGGATGAAAAAGAGTTGTATCAGTTCCGCAAGACGTTGAAC
TCACAAAACCACGCGTTCGGTCCAACCTATGCATTGGTGGAACAAGAGATTGCCGCTGCCGAGGCGAAACGCAGTGAGAT
GATCAACTTAAAGCAGGTCGGTCAAGTTTCCGAGGCGTTTGAAACCGGACAAGCCTTATCGAATCAAGTAGGTCACATCC
GTGAACTGATTCGGGTCATTCCGCAATTCGTACGAACGGTTCAAGTGGAGTTGAAACAGCAGCTTCAACAACTCCGGGCT
GGACATAAGGAAATGCAAATGGACGGATATGCACTTGAACCACTAGGATTAATGGAAGAAATCGATCAAGCGGAAAATCG
TCGAGAAGAGCTGATGGTTCGAATTGAACGCTTGGAATTTGATCATTTCGAAGAGGACATGCAACAGCTGAGTTCGGATA
TCGACCAATTATTCGAAGCGTTCCGAACAGAGGTTGATGCCCGCCAATACGTGAAAAAAGAATTTGCGACGATACAAGAG
CGCGAATTGCAATCTAGCGAAATCATGAATCACTTACAGACGGAAATGTCTCGACTTGTAAGCAATTATGAGATCAATGC
ACGCGTCGGAGAAGAGTTCGAACAATTAGAACGTGAACGGGCGACGCTCACGGCGAATGTACTTGATATCGAACAAGCTC
TCGTCGCGCAAATGTTACCGTTCAGTATGATCAAATCAAAAGTGCAGGAAGCGAAACGGTCACTTGACCAATTCAGCGCC
ATGCATGAGCGTTTCATTGAAGATACGAATTCATTACGTAAAGAAGAGCTTGAGGTCCGTCACAAGTTAGAAACGTGGAA
GAAAGAACTGTCTGGGCATCGTCGCCTGTTAGCGAAAAGTGCGATGCCGGTTGTTCCGAATGATCTGTCGAACGACTTAC
GTCAGCTCCAAAAAGGTGTCCAATCGTTAGACGAACAGTTTGACAAAGCACCGTTCAACATGACGTATATCGTCGGGCTT
AGCCATGATGTCGAAGAGATGATGGACAACTTCCGTGACCGTGTCCATGCACTGATTCGTCAAGTGACGTATGCGGAACA
GTTGCTACAATATGCTAACCGTTTCCGACGCCGTGACAACGAGGTTCATATCGCCTTGACGCTTGCAGAAAACAAGTTTT
TGCATGGAGAGTATGGTACTGCGGTCGAGATCGGTGAGCGGGTGCTCGGTCGATTCGATGAGAACGGAGCCAATGAAATT
CGTCAACGAGTGGATAAAGGGTTGGAACAGCAGGAATTGCTAAAAAAATAA

Upstream 100 bases:

>100_bases
GGTTCTATAATATGATTAGGTATATCTATTCTTATAAAATACTTCTTTTTTATATAAAGGTACATAAGTCCACGAAAGCG
GCTTGGAGGTTGTGACAAAG

Downstream 100 bases:

>100_bases
ACGATGCATGAAGATTGACGGAAACGGGAAAAACGTAGACGTCAATCTTTTTTCAATCAAGGAGGAATCGTCAGATGGGT
ACACTATGGGTCAACGGGAA

Product: septation ring formation regulator EzrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MDYGIYGLIIGIIVVVLGGMLGSMLIRRNFYQKIDDLDMRKQSVLSASIPVELQKFKQWPMEGETKEKFDRWHQSWDELV
SVHAGQIDEALYRAEEDLDKYRFMKVKADLNATEQLIEELETMVHAMLDEMDEFTTHHTSLMDIVKQDEKELYQFRKTLN
SQNHAFGPTYALVEQEIAAAEAKRSEMINLKQVGQVSEAFETGQALSNQVGHIRELIRVIPQFVRTVQVELKQQLQQLRA
GHKEMQMDGYALEPLGLMEEIDQAENRREELMVRIERLEFDHFEEDMQQLSSDIDQLFEAFRTEVDARQYVKKEFATIQE
RELQSSEIMNHLQTEMSRLVSNYEINARVGEEFEQLERERATLTANVLDIEQALVAQMLPFSMIKSKVQEAKRSLDQFSA
MHERFIEDTNSLRKEELEVRHKLETWKKELSGHRRLLAKSAMPVVPNDLSNDLRQLQKGVQSLDEQFDKAPFNMTYIVGL
SHDVEEMMDNFRDRVHALIRQVTYAEQLLQYANRFRRRDNEVHIALTLAENKFLHGEYGTAVEIGERVLGRFDENGANEI
RQRVDKGLEQQELLKK

Sequences:

>Translated_576_residues
MDYGIYGLIIGIIVVVLGGMLGSMLIRRNFYQKIDDLDMRKQSVLSASIPVELQKFKQWPMEGETKEKFDRWHQSWDELV
SVHAGQIDEALYRAEEDLDKYRFMKVKADLNATEQLIEELETMVHAMLDEMDEFTTHHTSLMDIVKQDEKELYQFRKTLN
SQNHAFGPTYALVEQEIAAAEAKRSEMINLKQVGQVSEAFETGQALSNQVGHIRELIRVIPQFVRTVQVELKQQLQQLRA
GHKEMQMDGYALEPLGLMEEIDQAENRREELMVRIERLEFDHFEEDMQQLSSDIDQLFEAFRTEVDARQYVKKEFATIQE
RELQSSEIMNHLQTEMSRLVSNYEINARVGEEFEQLERERATLTANVLDIEQALVAQMLPFSMIKSKVQEAKRSLDQFSA
MHERFIEDTNSLRKEELEVRHKLETWKKELSGHRRLLAKSAMPVVPNDLSNDLRQLQKGVQSLDEQFDKAPFNMTYIVGL
SHDVEEMMDNFRDRVHALIRQVTYAEQLLQYANRFRRRDNEVHIALTLAENKFLHGEYGTAVEIGERVLGRFDENGANEI
RQRVDKGLEQQELLKK
>Mature_576_residues
MDYGIYGLIIGIIVVVLGGMLGSMLIRRNFYQKIDDLDMRKQSVLSASIPVELQKFKQWPMEGETKEKFDRWHQSWDELV
SVHAGQIDEALYRAEEDLDKYRFMKVKADLNATEQLIEELETMVHAMLDEMDEFTTHHTSLMDIVKQDEKELYQFRKTLN
SQNHAFGPTYALVEQEIAAAEAKRSEMINLKQVGQVSEAFETGQALSNQVGHIRELIRVIPQFVRTVQVELKQQLQQLRA
GHKEMQMDGYALEPLGLMEEIDQAENRREELMVRIERLEFDHFEEDMQQLSSDIDQLFEAFRTEVDARQYVKKEFATIQE
RELQSSEIMNHLQTEMSRLVSNYEINARVGEEFEQLERERATLTANVLDIEQALVAQMLPFSMIKSKVQEAKRSLDQFSA
MHERFIEDTNSLRKEELEVRHKLETWKKELSGHRRLLAKSAMPVVPNDLSNDLRQLQKGVQSLDEQFDKAPFNMTYIVGL
SHDVEEMMDNFRDRVHALIRQVTYAEQLLQYANRFRRRDNEVHIALTLAENKFLHGEYGTAVEIGERVLGRFDENGANEI
RQRVDKGLEQQELLKK

Specific function: Negative regulator of ftsZ ring formation; modulates the frequency and position of ftsZ ring formation. Inhibits ftsZ ring formation at polar sites. Interacts either with ftsZ or with one of its binding partners to promote depolymerization [H]

COG id: COG4477

COG function: function code D; Negative regulator of septation ring formation

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein. Note=Colocalized with ftsZ to the nascent septal site (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ezrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010379 [H]

Pfam domain/function: PF06160 EzrA [H]

EC number: NA

Molecular weight: Translated: 67351; Mature: 67351

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA