Click here to switch to the map view.

The map label for this gene is phoR [H]

Identifier: 229916393

GI number: 229916393

Start: 614502

End: 616229

Strand: Reverse

Name: phoR [H]

Synonym: EAT1b_0663

Alternate gene names: 229916393

Gene position: 616229-614502 (Counterclockwise)

Preceding gene: 229916394

Following gene: 229916392

Centisome position: 20.54

GC content: 48.96

Gene sequence:

>1728_bases
ATGAAGACGTATCGCTCTAGATTTATGACGACTCTCATTTTTCTTGTGACCGGTGTCTTGTTGACGCTCGGGATTGTCCT
TGGGCAACTCTTCAAAGACTTTTATCTGGATTCTGAACGAGACCGTCTAAAAGAAGATGCTCAATTGGCAGCCCTCTACC
TCGAAGGAGGCGAATTGGACGAGATTCGTGAGTATGTCGGTCAAATCGATGACGGGAGCAGTTTTGATATTCTCCTTCTG
AATAGTCGGATGGAGGTAATTGCTGGCACGCCGTTTCGCGTCGGGTCCATCGATTATAAAATCGACCCGAGTATGGTCCC
TGAGGAAGGGACGTTCGGTGAAGCGGATGAGGACGAGTTGATTCAATACACAAAACCGATTGAACTTGCGACGGGTGGGA
CAGTCTATTTAACATTCATCCGTTATGTATCGGATTTAGAAGGGGTGTACAATCGCATCTGGTTGACGATTGCCCTTGCG
CTCTTCTTCTCCTTCTTCATTATTTTGTTCGTGCTTCAACATTTGACGAATCAATTTATTCGACCAATTGATGAGGCGAC
GATCGTCTTGCGGGAACTAGCAGACGGGAATTACAGGGCCCGTGTGTATGAACTCAGAAATGATGAGGAGACAGGTAGCC
TAGCAGGGTCGATCAACGTACTTGCTCGGAATTTGGAGTCGATTTCTCTCGGGGAGTCTGTGCAACGGGCGAGACTCGAA
TCGTTAATCGAGTATATGGGGGCGGGTCTTCTGCTCGTCGACGAGCGTGGGATCGTCACGTTGGTCAACCGTTCTTACCG
TGAGATGTTCCAATACGATGATTTATCGATCGGACAGTTTTATCACGGGATTCTACCGAGTCCCGAGGTAGAAACACTGA
TCGAAGACGTCTATCTGACGGAGGAGGTCCACCGCCGTCAATTATCGATTCGAACGGGTTTCAATCAAAAAACGTATATG
GTATCCGCGGCACCGATTTTCAGTGACACCGGGATGCTTCGCGGCACGACGTTGTTGTTCAACGATATTACAGAATTGAA
GCGACTTGAGAAGATGCGGAAAGACTTCGTGGCGAACGTCAGCCATGAGTTGAAGACACCGCTCACGTCCATTCGTGGGT
TTAGTGAGACGCTTCTAGATGGGGCGAAAGAAGTCCCGGAACTTCGAGACCAGTTTTTAGACATCATCCAAAAAGAAGCG
ACGCGGATGCAGATGCTTGTTGAGGATCTCCTTGAATTGTCGAGATTGGAGCGGGATGACTTCCAAATGGAGTTGGTGTC
CGTCGACTTGAATCAACTCGTCGATGAGGTCTGCCTCCTGCTCAGTCAAAAGGCGAGCAAGAAGTCGATTCAGCTAGAAG
CGAAACACGAGGGGACGGTCGTCTTGCAGGCGGACCTGAACCGAATGAAGCAAGTTATCATGAACTTGGTTGCCAACGCC
ATCAACTATTCACCAGAAGGAAGTCGTGTCGAAATCGCCGTAGAAGCGAAGGCGGATTCCTACAAACTTCGTGTCAAGGA
CAACGGAATCGGGATTGCCGAAAAAGAAGTGAGTCGCATCTTTGAACGCTTCTATCGTGTCGATAAGGCAAGAAGTCGGA
ACTCGGGTGGAACTGGCCTCGGACTCGCCATCGTGAAACACATCATCGATTTGCATCATGCCACGATTGACGTCGAGAGT
GAGGAAGGCAAAGGAACAACGTTTACCATTACATTCCCTCGGGTTTAA

Upstream 100 bases:

>100_bases
TCAGTCACCTTCGTGAAAAAATTGAACCGGTAACGAAGAAACCGACCTATATTAAAACGATTCGTGGTCTTGGCTATAAG
ATGGAGGAGCCGACTTCGGA

Downstream 100 bases:

>100_bases
CAATGACTTTATCGTTCGTTCATATTTACTTTACAATACCTTGCTATCCTATGAATGAGACCTCTTCATCATCTCGTGAC
TCGATCGGTGCTCATCTCCA

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MKTYRSRFMTTLIFLVTGVLLTLGIVLGQLFKDFYLDSERDRLKEDAQLAALYLEGGELDEIREYVGQIDDGSSFDILLL
NSRMEVIAGTPFRVGSIDYKIDPSMVPEEGTFGEADEDELIQYTKPIELATGGTVYLTFIRYVSDLEGVYNRIWLTIALA
LFFSFFIILFVLQHLTNQFIRPIDEATIVLRELADGNYRARVYELRNDEETGSLAGSINVLARNLESISLGESVQRARLE
SLIEYMGAGLLLVDERGIVTLVNRSYREMFQYDDLSIGQFYHGILPSPEVETLIEDVYLTEEVHRRQLSIRTGFNQKTYM
VSAAPIFSDTGMLRGTTLLFNDITELKRLEKMRKDFVANVSHELKTPLTSIRGFSETLLDGAKEVPELRDQFLDIIQKEA
TRMQMLVEDLLELSRLERDDFQMELVSVDLNQLVDEVCLLLSQKASKKSIQLEAKHEGTVVLQADLNRMKQVIMNLVANA
INYSPEGSRVEIAVEAKADSYKLRVKDNGIGIAEKEVSRIFERFYRVDKARSRNSGGTGLGLAIVKHIIDLHHATIDVES
EEGKGTTFTITFPRV

Sequences:

>Translated_575_residues
MKTYRSRFMTTLIFLVTGVLLTLGIVLGQLFKDFYLDSERDRLKEDAQLAALYLEGGELDEIREYVGQIDDGSSFDILLL
NSRMEVIAGTPFRVGSIDYKIDPSMVPEEGTFGEADEDELIQYTKPIELATGGTVYLTFIRYVSDLEGVYNRIWLTIALA
LFFSFFIILFVLQHLTNQFIRPIDEATIVLRELADGNYRARVYELRNDEETGSLAGSINVLARNLESISLGESVQRARLE
SLIEYMGAGLLLVDERGIVTLVNRSYREMFQYDDLSIGQFYHGILPSPEVETLIEDVYLTEEVHRRQLSIRTGFNQKTYM
VSAAPIFSDTGMLRGTTLLFNDITELKRLEKMRKDFVANVSHELKTPLTSIRGFSETLLDGAKEVPELRDQFLDIIQKEA
TRMQMLVEDLLELSRLERDDFQMELVSVDLNQLVDEVCLLLSQKASKKSIQLEAKHEGTVVLQADLNRMKQVIMNLVANA
INYSPEGSRVEIAVEAKADSYKLRVKDNGIGIAEKEVSRIFERFYRVDKARSRNSGGTGLGLAIVKHIIDLHHATIDVES
EEGKGTTFTITFPRV
>Mature_575_residues
MKTYRSRFMTTLIFLVTGVLLTLGIVLGQLFKDFYLDSERDRLKEDAQLAALYLEGGELDEIREYVGQIDDGSSFDILLL
NSRMEVIAGTPFRVGSIDYKIDPSMVPEEGTFGEADEDELIQYTKPIELATGGTVYLTFIRYVSDLEGVYNRIWLTIALA
LFFSFFIILFVLQHLTNQFIRPIDEATIVLRELADGNYRARVYELRNDEETGSLAGSINVLARNLESISLGESVQRARLE
SLIEYMGAGLLLVDERGIVTLVNRSYREMFQYDDLSIGQFYHGILPSPEVETLIEDVYLTEEVHRRQLSIRTGFNQKTYM
VSAAPIFSDTGMLRGTTLLFNDITELKRLEKMRKDFVANVSHELKTPLTSIRGFSETLLDGAKEVPELRDQFLDIIQKEA
TRMQMLVEDLLELSRLERDDFQMELVSVDLNQLVDEVCLLLSQKASKKSIQLEAKHEGTVVLQADLNRMKQVIMNLVANA
INYSPEGSRVEIAVEAKADSYKLRVKDNGIGIAEKEVSRIFERFYRVDKARSRNSGGTGLGLAIVKHIIDLHHATIDVES
EEGKGTTFTITFPRV

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=239, Percent_Identity=38.4937238493724, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=35.3448275862069, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1788393, Length=236, Percent_Identity=29.6610169491525, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1789149, Length=225, Percent_Identity=33.7777777777778, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI145693157, Length=220, Percent_Identity=33.6363636363636, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI48994928, Length=269, Percent_Identity=29.7397769516729, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1788549, Length=382, Percent_Identity=28.0104712041885, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=30.3964757709251, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786783, Length=239, Percent_Identity=30.9623430962343, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1790861, Length=235, Percent_Identity=32.7659574468085, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790346, Length=238, Percent_Identity=32.3529411764706, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1787894, Length=235, Percent_Identity=28.5106382978723, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=31.0043668122271, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1788279, Length=230, Percent_Identity=30.8695652173913, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=30, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789808, Length=243, Percent_Identity=27.5720164609054, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789403, Length=218, Percent_Identity=27.9816513761468, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1790551, Length=219, Percent_Identity=30.1369863013699, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI87081816, Length=238, Percent_Identity=26.4705882352941, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790300, Length=231, Percent_Identity=28.1385281385281, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65206; Mature: 65206

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50885 HAMP ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYRSRFMTTLIFLVTGVLLTLGIVLGQLFKDFYLDSERDRLKEDAQLAALYLEGGELD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEEECCCCHH
EIREYVGQIDDGSSFDILLLNSRMEVIAGTPFRVGSIDYKIDPSMVPEEGTFGEADEDEL
HHHHHHCCCCCCCCEEEEEECCCCHHHCCCCEEECCCCEEECCCCCCCCCCCCCCCHHHH
IQYTKPIELATGGTVYLTFIRYVSDLEGVYNRIWLTIALALFFSFFIILFVLQHLTNQFI
HHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RPIDEATIVLRELADGNYRARVYELRNDEETGSLAGSINVLARNLESISLGESVQRARLE
CCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLIEYMGAGLLLVDERGIVTLVNRSYREMFQYDDLSIGQFYHGILPSPEVETLIEDVYLT
HHHHHHCCCEEEEECCCEEEHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHH
EEVHRRQLSIRTGFNQKTYMVSAAPIFSDTGMLRGTTLLFNDITELKRLEKMRKDFVANV
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SHELKTPLTSIRGFSETLLDGAKEVPELRDQFLDIIQKEATRMQMLVEDLLELSRLERDD
HHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FQMELVSVDLNQLVDEVCLLLSQKASKKSIQLEAKHEGTVVLQADLNRMKQVIMNLVANA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHH
INYSPEGSRVEIAVEAKADSYKLRVKDNGIGIAEKEVSRIFERFYRVDKARSRNSGGTGL
HCCCCCCCEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHH
GLAIVKHIIDLHHATIDVESEEGKGTTFTITFPRV
HHHHHHHHHHHHHHEEEEECCCCCCCEEEEECCCC
>Mature Secondary Structure
MKTYRSRFMTTLIFLVTGVLLTLGIVLGQLFKDFYLDSERDRLKEDAQLAALYLEGGELD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEEECCCCHH
EIREYVGQIDDGSSFDILLLNSRMEVIAGTPFRVGSIDYKIDPSMVPEEGTFGEADEDEL
HHHHHHCCCCCCCCEEEEEECCCCHHHCCCCEEECCCCEEECCCCCCCCCCCCCCCHHHH
IQYTKPIELATGGTVYLTFIRYVSDLEGVYNRIWLTIALALFFSFFIILFVLQHLTNQFI
HHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RPIDEATIVLRELADGNYRARVYELRNDEETGSLAGSINVLARNLESISLGESVQRARLE
CCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLIEYMGAGLLLVDERGIVTLVNRSYREMFQYDDLSIGQFYHGILPSPEVETLIEDVYLT
HHHHHHCCCEEEEECCCEEEHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHH
EEVHRRQLSIRTGFNQKTYMVSAAPIFSDTGMLRGTTLLFNDITELKRLEKMRKDFVANV
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SHELKTPLTSIRGFSETLLDGAKEVPELRDQFLDIIQKEATRMQMLVEDLLELSRLERDD
HHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FQMELVSVDLNQLVDEVCLLLSQKASKKSIQLEAKHEGTVVLQADLNRMKQVIMNLVANA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHH
INYSPEGSRVEIAVEAKADSYKLRVKDNGIGIAEKEVSRIFERFYRVDKARSRNSGGTGL
HCCCCCCCEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHH
GLAIVKHIIDLHHATIDVESEEGKGTTFTITFPRV
HHHHHHHHHHHHHHEEEEECCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]