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The map label for this gene is phoP [H]

Identifier: 229916394

GI number: 229916394

Start: 616226

End: 616927

Strand: Reverse

Name: phoP [H]

Synonym: EAT1b_0664

Alternate gene names: 229916394

Gene position: 616927-616226 (Counterclockwise)

Preceding gene: 229916395

Following gene: 229916393

Centisome position: 20.56

GC content: 45.73

Gene sequence:

>702_bases
GTGGCTGATAAAGTAATTGTTGTCGACGATGAAGTGTCGATTGCGACATTATTGAAATTTAATTTAGAACAGGCTGGCTT
TGAAGTAGAGACGGCGCACGACGGCAAAACCGGATTGGAATTGGCTGAGAAAAAGGACGCCGTGCTCATTGTGCTCGATT
TGATGCTACCGGAGATGGATGGACTTGAAGTGTGCAAACGACTTCGTCAGCAAAAAGTCAATACACCGATTTTAATGCTC
ACGGCAAAAGATGATGAGTTTGATAAAGTATTGGGGCTCGAGCTCGGAGCGGACGATTATTTGACGAAACCGTTCAGCCC
ACGTGAAGTAGTCGCCCGTGTCAAAGCGATTCTTAGACGTTCTGCCCCGCAAGAATCGGCGGTTGAAGAGGACATCATTC
AAATCGGTGATGTTAAAATCGTCGCTTCAAACTACGAAGTGTTCAAGCAAGGAGAGCGCCTCGAATTGACGCCGAAAGAA
TTCGAATTGTTAGCCTATCTGGCGAAAAATAAAGGACGCGTGTTGACGCGAGACCAATTGTTATCGGCCATTTGGAATTA
TGACTTTGTGGGTGATACCCGGATCGTTGATGTCCATATCAGTCACCTTCGTGAAAAAATTGAACCGGTAACGAAGAAAC
CGACCTATATTAAAACGATTCGTGGTCTTGGCTATAAGATGGAGGAGCCGACTTCGGAATGA

Upstream 100 bases:

>100_bases
TTGTTTTGTTTTTGTAAAGATTTGCTTTGAGGTTGGTCGTTTCAAGCATTGATTTGTAAAATAGAAAGTGACATTTGATG
GTTTAAGAGGAGGAAGCAGT

Downstream 100 bases:

>100_bases
AGACGTATCGCTCTAGATTTATGACGACTCTCATTTTTCTTGTGACCGGTGTCTTGTTGACGCTCGGGATTGTCCTTGGG
CAACTCTTCAAAGACTTTTA

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MADKVIVVDDEVSIATLLKFNLEQAGFEVETAHDGKTGLELAEKKDAVLIVLDLMLPEMDGLEVCKRLRQQKVNTPILML
TAKDDEFDKVLGLELGADDYLTKPFSPREVVARVKAILRRSAPQESAVEEDIIQIGDVKIVASNYEVFKQGERLELTPKE
FELLAYLAKNKGRVLTRDQLLSAIWNYDFVGDTRIVDVHISHLREKIEPVTKKPTYIKTIRGLGYKMEEPTSE

Sequences:

>Translated_233_residues
MADKVIVVDDEVSIATLLKFNLEQAGFEVETAHDGKTGLELAEKKDAVLIVLDLMLPEMDGLEVCKRLRQQKVNTPILML
TAKDDEFDKVLGLELGADDYLTKPFSPREVVARVKAILRRSAPQESAVEEDIIQIGDVKIVASNYEVFKQGERLELTPKE
FELLAYLAKNKGRVLTRDQLLSAIWNYDFVGDTRIVDVHISHLREKIEPVTKKPTYIKTIRGLGYKMEEPTSE
>Mature_232_residues
ADKVIVVDDEVSIATLLKFNLEQAGFEVETAHDGKTGLELAEKKDAVLIVLDLMLPEMDGLEVCKRLRQQKVNTPILMLT
AKDDEFDKVLGLELGADDYLTKPFSPREVVARVKAILRRSAPQESAVEEDIIQIGDVKIVASNYEVFKQGERLELTPKEF
ELLAYLAKNKGRVLTRDQLLSAIWNYDFVGDTRIVDVHISHLREKIEPVTKKPTYIKTIRGLGYKMEEPTSE

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=40.8888888888889, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=40.174672489083, Blast_Score=170, Evalue=8e-44,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=39.5652173913043, Blast_Score=166, Evalue=9e-43,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=40.2654867256637, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=39.1304347826087, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=39.5555555555556, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=40.6113537117904, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=36.1607142857143, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=36.1607142857143, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=35.3982300884956, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=32.7510917030568, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1787229, Length=211, Percent_Identity=31.2796208530806, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=29.8701298701299, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788550, Length=103, Percent_Identity=33.0097087378641, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=36.9369369369369, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790437, Length=101, Percent_Identity=33.6633663366337, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26342; Mature: 26211

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKVIVVDDEVSIATLLKFNLEQAGFEVETAHDGKTGLELAEKKDAVLIVLDLMLPEMD
CCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHCCCCEEEEEEEHHCCCCC
GLEVCKRLRQQKVNTPILMLTAKDDEFDKVLGLELGADDYLTKPFSPREVVARVKAILRR
HHHHHHHHHHHHCCCCEEEEEECCCCHHHHHCEEECCCHHCCCCCCHHHHHHHHHHHHHH
SAPQESAVEEDIIQIGDVKIVASNYEVFKQGERLELTPKEFELLAYLAKNKGRVLTRDQL
CCCCHHHHHHHHHHHCCEEEEECCHHHHHCCCCEEECHHHHHHHHHHHHCCCCEEEHHHH
LSAIWNYDFVGDTRIVDVHISHLREKIEPVTKKPTYIKTIRGLGYKMEEPTSE
HHHHHCCCCCCCCEEEEHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ADKVIVVDDEVSIATLLKFNLEQAGFEVETAHDGKTGLELAEKKDAVLIVLDLMLPEMD
CCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHCCCCEEEEEEEHHCCCCC
GLEVCKRLRQQKVNTPILMLTAKDDEFDKVLGLELGADDYLTKPFSPREVVARVKAILRR
HHHHHHHHHHHHCCCCEEEEEECCCCHHHHHCEEECCCHHCCCCCCHHHHHHHHHHHHHH
SAPQESAVEEDIIQIGDVKIVASNYEVFKQGERLELTPKEFELLAYLAKNKGRVLTRDQL
CCCCHHHHHHHHHHHCCEEEEECCHHHHHCCCCEEECHHHHHHHHHHHHCCCCEEEHHHH
LSAIWNYDFVGDTRIVDVHISHLREKIEPVTKKPTYIKTIRGLGYKMEEPTSE
HHHHHCCCCCCCCEEEEHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]