Click here to switch to the map view.

The map label for this gene is coaE [H]

Identifier: 229916390

GI number: 229916390

Start: 610232

End: 610837

Strand: Reverse

Name: coaE [H]

Synonym: EAT1b_0660

Alternate gene names: 229916390

Gene position: 610837-610232 (Counterclockwise)

Preceding gene: 229916391

Following gene: 229916388

Centisome position: 20.36

GC content: 47.85

Gene sequence:

>606_bases
ATGTTGAAGATTGGTTTGACTGGTGGGATCGCAACCGGAAAGTCTACGGTATCGCGACTGTTTCGAGAGCGAGGTATTCC
GATTATCGATGCCGATTTGATTGCCAGGACTGTCGTTGAACCAGGAGGAAAGGCGATTGAAGGGGTGAGGGCCGCATTTC
CAAAGTGTTTTGTGGGCGACGTGCTGAACCGTCCTGCCCTCGGTCGGGAAATCTTCCATGATGAAGCAAAGCGTCAGCAA
TTGAATCAATTGATGCATCCAGCGATTCGAGAAGAAATGAACGAGCAGATGCGAACGTATGAGGCATCGGGGGAACCGGT
CGTCATTTTTGATATTCCGTTACTGTTTGAAGGGACGATGCTTGATTTGGTTGATTATTCTGTGGTCGTCTACTGCCGTG
AAGAGATTCAACTAATGCGTCTCATGGAACGGAATGGATTGACGAAAGAAGAGGCGCTCGCCCGTATTCGCTCACAGATT
CCAATCGAAGATAAAAAACATCAGGCTGATTTCCTCATAAACAATAATGGGGCATTGGGGGACCTTCCTCCGCAAATCAA
TCGTCTGGTTGAGCAGTTTCAAACGATACAAAAAGAAGGCGACTGA

Upstream 100 bases:

>100_bases
CCGTGCCGTCGATGCGGACATGAAATTGAAAAGATGAAATTGGGCGGGCGAGGCACGCATTACTGTCCGCACTGTCAACA
ACGTTAAGGGGTGGGCGTGT

Downstream 100 bases:

>100_bases
TAATCGCCTTCTTTTTAGTTTAATGGATCGGATTCTGGAGACCCTTTTTTCCATGTATCATAAATCGCACGCCCATCGCT
CGGATGCCCGTTCGAATAAT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MLKIGLTGGIATGKSTVSRLFRERGIPIIDADLIARTVVEPGGKAIEGVRAAFPKCFVGDVLNRPALGREIFHDEAKRQQ
LNQLMHPAIREEMNEQMRTYEASGEPVVIFDIPLLFEGTMLDLVDYSVVVYCREEIQLMRLMERNGLTKEEALARIRSQI
PIEDKKHQADFLINNNGALGDLPPQINRLVEQFQTIQKEGD

Sequences:

>Translated_201_residues
MLKIGLTGGIATGKSTVSRLFRERGIPIIDADLIARTVVEPGGKAIEGVRAAFPKCFVGDVLNRPALGREIFHDEAKRQQ
LNQLMHPAIREEMNEQMRTYEASGEPVVIFDIPLLFEGTMLDLVDYSVVVYCREEIQLMRLMERNGLTKEEALARIRSQI
PIEDKKHQADFLINNNGALGDLPPQINRLVEQFQTIQKEGD
>Mature_201_residues
MLKIGLTGGIATGKSTVSRLFRERGIPIIDADLIARTVVEPGGKAIEGVRAAFPKCFVGDVLNRPALGREIFHDEAKRQQ
LNQLMHPAIREEMNEQMRTYEASGEPVVIFDIPLLFEGTMLDLVDYSVVVYCREEIQLMRLMERNGLTKEEALARIRSQI
PIEDKKHQADFLINNNGALGDLPPQINRLVEQFQTIQKEGD

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=181, Percent_Identity=43.646408839779, Blast_Score=143, Evalue=1e-34,
Organism=Homo sapiens, GI191252795, Length=181, Percent_Identity=43.646408839779, Blast_Score=143, Evalue=1e-34,
Organism=Homo sapiens, GI110227607, Length=174, Percent_Identity=28.1609195402299, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI110227605, Length=159, Percent_Identity=30.188679245283, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI110227603, Length=159, Percent_Identity=30.188679245283, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI110227601, Length=159, Percent_Identity=30.188679245283, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI205277394, Length=159, Percent_Identity=30.188679245283, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1786292, Length=192, Percent_Identity=35.4166666666667, Blast_Score=108, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17554944, Length=202, Percent_Identity=40.5940594059406, Blast_Score=160, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI25143409, Length=192, Percent_Identity=27.6041666666667, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320402, Length=201, Percent_Identity=43.2835820895522, Blast_Score=154, Evalue=8e-39,
Organism=Drosophila melanogaster, GI24644728, Length=182, Percent_Identity=40.6593406593407, Blast_Score=147, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24658602, Length=166, Percent_Identity=31.3253012048193, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22628; Mature: 22628

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIGLTGGIATGKSTVSRLFRERGIPIIDADLIARTVVEPGGKAIEGVRAAFPKCFVGD
CEEECCCCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VLNRPALGREIFHDEAKRQQLNQLMHPAIREEMNEQMRTYEASGEPVVIFDIPLLFEGTM
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHCCHH
LDLVDYSVVVYCREEIQLMRLMERNGLTKEEALARIRSQIPIEDKKHQADFLINNNGALG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCC
DLPPQINRLVEQFQTIQKEGD
CCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKIGLTGGIATGKSTVSRLFRERGIPIIDADLIARTVVEPGGKAIEGVRAAFPKCFVGD
CEEECCCCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VLNRPALGREIFHDEAKRQQLNQLMHPAIREEMNEQMRTYEASGEPVVIFDIPLLFEGTM
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHCCHH
LDLVDYSVVVYCREEIQLMRLMERNGLTKEEALARIRSQIPIEDKKHQADFLINNNGALG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCC
DLPPQINRLVEQFQTIQKEGD
CCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]