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The map label for this gene is yqhT [H]

Identifier: 229916258

GI number: 229916258

Start: 480924

End: 481994

Strand: Reverse

Name: yqhT [H]

Synonym: EAT1b_0527

Alternate gene names: 229916258

Gene position: 481994-480924 (Counterclockwise)

Preceding gene: 229916259

Following gene: 229916257

Centisome position: 16.07

GC content: 49.11

Gene sequence:

>1071_bases
ATGATTGAACGCGTAAACAAACTGCAAGCACAGTTAGAAGAAAACGAAATTGATGCGTTGCTCGTCACAAAACGTGAGAA
TATCCGCTACTTATCTGGTTTCACAGGATCGAGCGGTGTCATCGTCATCACGTCGAATTCGGCAAGTTTTATCACGGACT
TCCGTTACACGGAACAGGCGAACGATCAAGTGAAAGGGTATGACATCATCGAGCTTGATACGTCACTCATCAAGTCGGTA
GCAGATGTCGTGTCACGTGAATCCATCAAGCGCCTTGGCATTGAGCAGGATGCGATGACAGTGGGGCAATATCGTGCCTA
TGAAAAAGAAGTGGACGCTCAACTTATTGAAACGTCTGGAATCGTAGAAAAACTGCGCTTGATTAAGGATGAATCAGAGA
TTAAGATTATGAAGGAAGCTGCGGCAATCGCTGATGCGGCGTATGCCCATATCCAGACGTTCATCCGTCCTGGTCGTACC
GAAAGAGAAGTCGCGAACGAACTTGAAATGTTCATGCGTTCAAAAGGTGCCGACTCGTCATCGTTCGACATGATTGTCGC
CTCGGGTCTCCGTTCGGCGCTACCGCACGGTGTGGCCAGCGATAAAGTCATCGAAACTGGAGAATTGGTTACGCTTGATT
TCGGGGCTTACTATAAAGGGTACTGCTCAGATATCACGCGTACGCTTGCAATCGGTCCGATTTCGGATGAGTTGCGTCAA
ATCTACGATACGGTACTCCGTGCTCAACTTGCTGGCGTAGAAGGCACACGAGCCGGAATCACTGGCATTGAGGCGGATGC
GTTGACACGCGATATTATTAAAGAAGCTGGATATGGCGAATACTTCGGCCACTCGACAGGACATGGTCTCGGAATGGAAG
TGCATGAGGCCCCAGGATTATCGTTCCGTTCGGAAACGGTGCTCGAACCTGGTATGGTCGTGACGATCGAGCCGGGTATT
TACATCAATGGCGTCGGTGGTTGCCGAATTGAAGACGATGTCGTCATCACAGAAGACGGATGCTACCGTCTGACACAGTC
GCCAAAAGAGTTAATTACGATTGAGGCATAA

Upstream 100 bases:

>100_bases
TCAAAACTTGCTGCCGTCTGTATCGGTGTCATTACCGGTTTTGGACTCACGAGCTATACGTTAGCGATGCATGCACTAAT
CGAACATTGGAGGAATCGAC

Downstream 100 bases:

>100_bases
GCTTCATCTGAATTTAGGAGGAAATCAACATGGTATCAGTTAACGATTTAAAAACAGGATTGACGGTTAAAACGTCTGAC
GGTTCGATTTGGCAAGTCAT

Product: peptidase M24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MIERVNKLQAQLEENEIDALLVTKRENIRYLSGFTGSSGVIVITSNSASFITDFRYTEQANDQVKGYDIIELDTSLIKSV
ADVVSRESIKRLGIEQDAMTVGQYRAYEKEVDAQLIETSGIVEKLRLIKDESEIKIMKEAAAIADAAYAHIQTFIRPGRT
EREVANELEMFMRSKGADSSSFDMIVASGLRSALPHGVASDKVIETGELVTLDFGAYYKGYCSDITRTLAIGPISDELRQ
IYDTVLRAQLAGVEGTRAGITGIEADALTRDIIKEAGYGEYFGHSTGHGLGMEVHEAPGLSFRSETVLEPGMVVTIEPGI
YINGVGGCRIEDDVVITEDGCYRLTQSPKELITIEA

Sequences:

>Translated_356_residues
MIERVNKLQAQLEENEIDALLVTKRENIRYLSGFTGSSGVIVITSNSASFITDFRYTEQANDQVKGYDIIELDTSLIKSV
ADVVSRESIKRLGIEQDAMTVGQYRAYEKEVDAQLIETSGIVEKLRLIKDESEIKIMKEAAAIADAAYAHIQTFIRPGRT
EREVANELEMFMRSKGADSSSFDMIVASGLRSALPHGVASDKVIETGELVTLDFGAYYKGYCSDITRTLAIGPISDELRQ
IYDTVLRAQLAGVEGTRAGITGIEADALTRDIIKEAGYGEYFGHSTGHGLGMEVHEAPGLSFRSETVLEPGMVVTIEPGI
YINGVGGCRIEDDVVITEDGCYRLTQSPKELITIEA
>Mature_356_residues
MIERVNKLQAQLEENEIDALLVTKRENIRYLSGFTGSSGVIVITSNSASFITDFRYTEQANDQVKGYDIIELDTSLIKSV
ADVVSRESIKRLGIEQDAMTVGQYRAYEKEVDAQLIETSGIVEKLRLIKDESEIKIMKEAAAIADAAYAHIQTFIRPGRT
EREVANELEMFMRSKGADSSSFDMIVASGLRSALPHGVASDKVIETGELVTLDFGAYYKGYCSDITRTLAIGPISDELRQ
IYDTVLRAQLAGVEGTRAGITGIEADALTRDIIKEAGYGEYFGHSTGHGLGMEVHEAPGLSFRSETVLEPGMVVTIEPGI
YINGVGGCRIEDDVVITEDGCYRLTQSPKELITIEA

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=379, Percent_Identity=28.2321899736148, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI260593665, Length=352, Percent_Identity=26.9886363636364, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI149589008, Length=355, Percent_Identity=26.7605633802817, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI260593663, Length=252, Percent_Identity=29.7619047619048, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI93141226, Length=185, Percent_Identity=33.5135135135135, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI264681563, Length=211, Percent_Identity=31.2796208530806, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI264681565, Length=372, Percent_Identity=26.0752688172043, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788728, Length=357, Percent_Identity=43.6974789915966, Blast_Score=292, Evalue=2e-80,
Organism=Escherichia coli, GI1789275, Length=264, Percent_Identity=32.5757575757576, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790282, Length=310, Percent_Identity=26.1290322580645, Blast_Score=81, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17508215, Length=314, Percent_Identity=26.7515923566879, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71989583, Length=272, Percent_Identity=26.4705882352941, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17509539, Length=237, Percent_Identity=30.8016877637131, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320922, Length=248, Percent_Identity=31.8548387096774, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6321118, Length=283, Percent_Identity=27.208480565371, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6322999, Length=295, Percent_Identity=25.4237288135593, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323273, Length=209, Percent_Identity=29.1866028708134, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357079, Length=303, Percent_Identity=30.03300330033, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI19920384, Length=261, Percent_Identity=29.1187739463602, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17137632, Length=368, Percent_Identity=26.6304347826087, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 38999; Mature: 38999

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIERVNKLQAQLEENEIDALLVTKRENIRYLSGFTGSSGVIVITSNSASFITDFRYTEQA
CCCHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCCCEEEEECCCCCEEEEEEHHHCC
NDQVKGYDIIELDTSLIKSVADVVSRESIKRLGIEQDAMTVGQYRAYEKEVDAQLIETSG
CCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IVEKLRLIKDESEIKIMKEAAAIADAAYAHIQTFIRPGRTEREVANELEMFMRSKGADSS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCC
SFDMIVASGLRSALPHGVASDKVIETGELVTLDFGAYYKGYCSDITRTLAIGPISDELRQ
CHHHHHHHHHHHHCCCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHH
IYDTVLRAQLAGVEGTRAGITGIEADALTRDIIKEAGYGEYFGHSTGHGLGMEVHEAPGL
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCC
SFRSETVLEPGMVVTIEPGIYINGVGGCRIEDDVVITEDGCYRLTQSPKELITIEA
CCCCCCCCCCCEEEEECCCEEEECCCCCEECCCEEEECCCCEECCCCCCCEEEECC
>Mature Secondary Structure
MIERVNKLQAQLEENEIDALLVTKRENIRYLSGFTGSSGVIVITSNSASFITDFRYTEQA
CCCHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCCCEEEEECCCCCEEEEEEHHHCC
NDQVKGYDIIELDTSLIKSVADVVSRESIKRLGIEQDAMTVGQYRAYEKEVDAQLIETSG
CCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IVEKLRLIKDESEIKIMKEAAAIADAAYAHIQTFIRPGRTEREVANELEMFMRSKGADSS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCC
SFDMIVASGLRSALPHGVASDKVIETGELVTLDFGAYYKGYCSDITRTLAIGPISDELRQ
CHHHHHHHHHHHHCCCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHH
IYDTVLRAQLAGVEGTRAGITGIEADALTRDIIKEAGYGEYFGHSTGHGLGMEVHEAPGL
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCC
SFRSETVLEPGMVVTIEPGIYINGVGGCRIEDDVVITEDGCYRLTQSPKELITIEA
CCCCCCCCCCCEEEEECCCEEEECCCCCEECCCEEEECCCCEECCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]