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The map label for this gene is aroQ

Identifier: 229916259

GI number: 229916259

Start: 481987

End: 482424

Strand: Reverse

Name: aroQ

Synonym: EAT1b_0528

Alternate gene names: 229916259

Gene position: 482424-481987 (Counterclockwise)

Preceding gene: 229916262

Following gene: 229916258

Centisome position: 16.08

GC content: 47.03

Gene sequence:

>438_bases
TTGCGGATTTTAGTTTTAAATGGACCGAATTTAAATCTACTGGGTCGTCGTGAACCGGATGTATATGGCGATGTGTCGTT
GAAAGGATTGGCGGCAGAACTGATGTTGCGCGCTCCAGAAGACGTTGAACTCACCTTTAAACAATCGAATCATGAGGGAG
ATTTAATTGATGCGCTACATGACGCTTTTGATTATGAGGGTGTCATATTGAATGCGGGTGCCTATACGCATACATCGATT
GCGATCCGGGATGCCATATCCGCTATCGCTGCCCCGGTCGTTGAAGTACATATCTCGAACGTGCATGCGCGCGAGACCTT
TCGGCATGAGTCAAAACTTGCTGCCGTCTGTATCGGTGTCATTACCGGTTTTGGACTCACGAGCTATACGTTAGCGATGC
ATGCACTAATCGAACATTGGAGGAATCGACATGATTGA

Upstream 100 bases:

>100_bases
CGTGATTTGTAAAAAAAACGAAAGGGCAGAAGGCTCGATTCACGTTCTTTCGATAAATTTGTTACAATAGATAAGACTTG
ACGAACGAGGGGGAAGAAGG

Downstream 100 bases:

>100_bases
ACGCGTAAACAAACTGCAAGCACAGTTAGAAGAAAACGAAATTGATGCGTTGCTCGTCACAAAACGTGAGAATATCCGCT
ACTTATCTGGTTTCACAGGA

Product: 3-dehydroquinate dehydratase, type II

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MRILVLNGPNLNLLGRREPDVYGDVSLKGLAAELMLRAPEDVELTFKQSNHEGDLIDALHDAFDYEGVILNAGAYTHTSI
AIRDAISAIAAPVVEVHISNVHARETFRHESKLAAVCIGVITGFGLTSYTLAMHALIEHWRNRHD

Sequences:

>Translated_145_residues
MRILVLNGPNLNLLGRREPDVYGDVSLKGLAAELMLRAPEDVELTFKQSNHEGDLIDALHDAFDYEGVILNAGAYTHTSI
AIRDAISAIAAPVVEVHISNVHARETFRHESKLAAVCIGVITGFGLTSYTLAMHALIEHWRNRHD
>Mature_145_residues
MRILVLNGPNLNLLGRREPDVYGDVSLKGLAAELMLRAPEDVELTFKQSNHEGDLIDALHDAFDYEGVILNAGAYTHTSI
AIRDAISAIAAPVVEVHISNVHARETFRHESKLAAVCIGVITGFGLTSYTLAMHALIEHWRNRHD

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_EXISA (C4L3G2)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002884905.1
- GeneID:   7871262
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_0528
- OMA:   IMVINGP
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15964; Mature: 15964

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 22-22 ACT_SITE 97-97 BINDING 71-71 BINDING 77-77 BINDING 84-84 BINDING 108-108

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVLNGPNLNLLGRREPDVYGDVSLKGLAAELMLRAPEDVELTFKQSNHEGDLIDALH
CEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
DAFDYEGVILNAGAYTHTSIAIRDAISAIAAPVVEVHISNVHARETFRHESKLAAVCIGV
HHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHH
ITGFGLTSYTLAMHALIEHWRNRHD
HHHCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRILVLNGPNLNLLGRREPDVYGDVSLKGLAAELMLRAPEDVELTFKQSNHEGDLIDALH
CEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
DAFDYEGVILNAGAYTHTSIAIRDAISAIAAPVVEVHISNVHARETFRHESKLAAVCIGV
HHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHH
ITGFGLTSYTLAMHALIEHWRNRHD
HHHCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA