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The map label for this gene is efp

Identifier: 229916257

GI number: 229916257

Start: 480328

End: 480894

Strand: Reverse

Name: efp

Synonym: EAT1b_0526

Alternate gene names: 229916257

Gene position: 480894-480328 (Counterclockwise)

Preceding gene: 229916258

Following gene: 229916256

Centisome position: 16.03

GC content: 47.09

Gene sequence:

>567_bases
ATGGTATCAGTTAACGATTTAAAAACAGGATTGACGGTTAAAACGTCTGACGGTTCGATTTGGCAAGTCATCGAGTTTCA
ACACGTAAAACCGGGTAAAGGCGCGGCATTCGTTCGTACGAAAATGCGTAACTTGCGTAACGGGGCAATCCAAGAAACGA
CGTTCCGTGGTGGAGAGAAAATCGAACGCGCACACATCGAGCGTAAACGCATGCAATATCTCTATCCAATGGGCGACACG
TATGTCTTCATGGACAATGAATCATACGAGCAACTTGAATTGACAAGCGCTCAAGTCAAGTCAGCACTTCCATATTTGCT
TGAGAACATGGAAGTCAGCATCGCGGACTACGAAGGGGAGATTCTTGGAATCGAGCTTCCAACGAGCGTTGTCTTGACGA
TCGTCGAAGCAGACCCGGGTGTAAAAGGTGACACGGCCTCGAACGTGAAGAAAAACGCGACAGTGGAAACAGGACACGTC
ATTCAAGTGCCACTTTTCATCGAACCAGGTGAAAAAGTGACAGTCGATACACGTACTGGAGAGTTCATGGGTCGTTATAA
CGGTTAA

Upstream 100 bases:

>100_bases
TCGTCATCACAGAAGACGGATGCTACCGTCTGACACAGTCGCCAAAAGAGTTAATTACGATTGAGGCATAAGCTTCATCT
GAATTTAGGAGGAAATCAAC

Downstream 100 bases:

>100_bases
TCCTTACGAGTGCTCATTCGAATGAATGGGTGCTCTTTTTTTCTCGTTGCATTCATTGGTCTGACCAGTTATAGTGAAGG
AGAGATTAGTACCAGGTATA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MVSVNDLKTGLTVKTSDGSIWQVIEFQHVKPGKGAAFVRTKMRNLRNGAIQETTFRGGEKIERAHIERKRMQYLYPMGDT
YVFMDNESYEQLELTSAQVKSALPYLLENMEVSIADYEGEILGIELPTSVVLTIVEADPGVKGDTASNVKKNATVETGHV
IQVPLFIEPGEKVTVDTRTGEFMGRYNG

Sequences:

>Translated_188_residues
MVSVNDLKTGLTVKTSDGSIWQVIEFQHVKPGKGAAFVRTKMRNLRNGAIQETTFRGGEKIERAHIERKRMQYLYPMGDT
YVFMDNESYEQLELTSAQVKSALPYLLENMEVSIADYEGEILGIELPTSVVLTIVEADPGVKGDTASNVKKNATVETGHV
IQVPLFIEPGEKVTVDTRTGEFMGRYNG
>Mature_188_residues
MVSVNDLKTGLTVKTSDGSIWQVIEFQHVKPGKGAAFVRTKMRNLRNGAIQETTFRGGEKIERAHIERKRMQYLYPMGDT
YVFMDNESYEQLELTSAQVKSALPYLLENMEVSIADYEGEILGIELPTSVVLTIVEADPGVKGDTASNVKKNATVETGHV
IQVPLFIEPGEKVTVDTRTGEFMGRYNG

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=181, Percent_Identity=39.7790055248619, Blast_Score=137, Evalue=3e-34,
Organism=Escherichia coli, GI87082061, Length=189, Percent_Identity=33.8624338624339, Blast_Score=107, Evalue=6e-25,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_EXISA (C4L3G0)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002884903.1
- GeneID:   7871260
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_0526
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20919; Mature: 20919

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSVNDLKTGLTVKTSDGSIWQVIEFQHVKPGKGAAFVRTKMRNLRNGAIQETTFRGGEK
CCCCCCCCCCCEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCHH
IERAHIERKRMQYLYPMGDTYVFMDNESYEQLELTSAQVKSALPYLLENMEVSIADYEGE
HHHHHHHHHHHHEECCCCCEEEEECCCCCHHEEHHHHHHHHHHHHHHCCCEEEEEECCCC
ILGIELPTSVVLTIVEADPGVKGDTASNVKKNATVETGHVIQVPLFIEPGEKVTVDTRTG
EEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCEEEEECCCC
EFMGRYNG
CEEEECCC
>Mature Secondary Structure
MVSVNDLKTGLTVKTSDGSIWQVIEFQHVKPGKGAAFVRTKMRNLRNGAIQETTFRGGEK
CCCCCCCCCCCEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCHH
IERAHIERKRMQYLYPMGDTYVFMDNESYEQLELTSAQVKSALPYLLENMEVSIADYEGE
HHHHHHHHHHHHEECCCCCEEEEECCCCCHHEEHHHHHHHHHHHHHHCCCEEEEEECCCC
ILGIELPTSVVLTIVEADPGVKGDTASNVKKNATVETGHVIQVPLFIEPGEKVTVDTRTG
EEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCEEEEECCCC
EFMGRYNG
CEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA