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The map label for this gene is fur [H]

Identifier: 229916187

GI number: 229916187

Start: 417627

End: 418106

Strand: Reverse

Name: fur [H]

Synonym: EAT1b_0456

Alternate gene names: 229916187

Gene position: 418106-417627 (Counterclockwise)

Preceding gene: 229916188

Following gene: 229916183

Centisome position: 13.94

GC content: 45.42

Gene sequence:

>480_bases
ATGGAAACGCGAATTGAACGAATTAAACAGCAATTGAGCGCCAAAGGATATAAATTAACACCACAACGTGAATCGACGGT
ACGAATCTTACTTGAGAATGAGAGTGACCATCTGAGTGCGGAGAACGTCTTCATGCTCGTGAAAAGCATCGCACCAGAAA
TTGGACTCGCAACGGTTTATCGCACATTAGAATTATTGACAGAGCTCGGCGTGGTCGATAAAGTCAACTTCGGTGACGGA
GTTGCACGATTTGACTTACGTCCTGAAGGGGCGAATCATTCGCACCACCATCTCGTCTGCGTCGAATGCGGCTCGGTCGA
GGAAATCATGGAAGACTTGCTCGTCGATGTTGAGAAAAAAGTCGAGAGCAAATATGAATTTTTGATTAAAGACCATCGCT
TGACGTTTCACGGGATTTGTAAAGTATGCCAAGCAAAAGGCGTCACGCTCGAAGGTCATAAAGCAGTCATCAACGGTTAA

Upstream 100 bases:

>100_bases
TACTTATATGATAAACTTACATAGTAATGATTTTAAATTGAAAATTGAGTAAAACTTCGGTATGCTTTCAGTAGTGAACT
ATGTAAAGAGGGGGCGCCTT

Downstream 100 bases:

>100_bases
TGTAGAAAGGACAGACGACCCCAACAGGTCATCTGTCCTTTTTCAATGTGTGATAGATCGCTTAGGAATCTACTTAGATT
GTCAATTCGATGATGTTGCC

Product: ferric uptake regulator, Fur family

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
METRIERIKQQLSAKGYKLTPQRESTVRILLENESDHLSAENVFMLVKSIAPEIGLATVYRTLELLTELGVVDKVNFGDG
VARFDLRPEGANHSHHHLVCVECGSVEEIMEDLLVDVEKKVESKYEFLIKDHRLTFHGICKVCQAKGVTLEGHKAVING

Sequences:

>Translated_159_residues
METRIERIKQQLSAKGYKLTPQRESTVRILLENESDHLSAENVFMLVKSIAPEIGLATVYRTLELLTELGVVDKVNFGDG
VARFDLRPEGANHSHHHLVCVECGSVEEIMEDLLVDVEKKVESKYEFLIKDHRLTFHGICKVCQAKGVTLEGHKAVING
>Mature_159_residues
METRIERIKQQLSAKGYKLTPQRESTVRILLENESDHLSAENVFMLVKSIAPEIGLATVYRTLELLTELGVVDKVNFGDG
VARFDLRPEGANHSHHHLVCVECGSVEEIMEDLLVDVEKKVESKYEFLIKDHRLTFHGICKVCQAKGVTLEGHKAVING

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=129, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17881; Mature: 17881

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METRIERIKQQLSAKGYKLTPQRESTVRILLENESDHLSAENVFMLVKSIAPEIGLATVY
CCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHH
RTLELLTELGVVDKVNFGDGVARFDLRPEGANHSHHHLVCVECGSVEEIMEDLLVDVEKK
HHHHHHHHCCCCEECCCCCCEEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
VESKYEFLIKDHRLTFHGICKVCQAKGVTLEGHKAVING
HHHHHHHHHHCCCCHHHHHHHHHHHCCCEECCCEEEECC
>Mature Secondary Structure
METRIERIKQQLSAKGYKLTPQRESTVRILLENESDHLSAENVFMLVKSIAPEIGLATVY
CCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHH
RTLELLTELGVVDKVNFGDGVARFDLRPEGANHSHHHLVCVECGSVEEIMEDLLVDVEKK
HHHHHHHHCCCCEECCCCCCEEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
VESKYEFLIKDHRLTFHGICKVCQAKGVTLEGHKAVING
HHHHHHHHHHCCCCHHHHHHHHHHHCCCEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]