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The map label for this gene is xerD [H]

Identifier: 229916183

GI number: 229916183

Start: 413889

End: 414776

Strand: Reverse

Name: xerD [H]

Synonym: EAT1b_0452

Alternate gene names: 229916183

Gene position: 414776-413889 (Counterclockwise)

Preceding gene: 229916187

Following gene: 229916182

Centisome position: 13.83

GC content: 50.9

Gene sequence:

>888_bases
ATGATGCGTTCGCATATCGAGTCATTTCTTCAATATATGACAGTTGAAAAGCGGATGTCCGCGAATACGAGACAGGCGTA
TGCGAGCGATTTGACGCAGTACGCATCGACCTTGACCCAACTTGGGGTAGAAGAGTGGAATGAGGTGACACGTTCGCATA
TCGTCAAACATATCGAAGAGCTGTCGCAAGCGGGGCGAGCCTCGTCTTCATTGAGACGAGCAGTCAGTTCAATCCGGATG
TTCCATCATCATCTAAAAATGACCGGAGTCACGACGACTGATCCGTCACTTTACCTAGAATCTCCAAAAGCAGAAAAGCA
ACTTCCGGACACGTGGTCACAAACGGAAGTCGAGCGACTGTTGGACAGCGTCCCGACGTCGGACCCGCTCTCACTACGAG
ACCGGGCTATGCTGGAGTTGCTTTACGGGACGGGGATGCGGGTCAGTGAACTTTTAGGTTTGGATTTGGATGATTTGCAG
TTCGAATTGGGGTATCTACAATGTGAAGGGAAAGGCGAGCGCGCACGAATCATCCCGGTATCCTCGGTCGCCCAAAGTTT
CGTCGAGCGTTACATCCAACAAGCTCGTAACGGACTTGGCGGTAGAGAGACCGAAGCGCTCTTTTTAAACGGCCGAGGAG
GACGGCTCAGTCGTCAAGGATTTTGGAAGATGATCAAACGACGAGCCAAACTTGCTGGAATTGAAAAAGAGATCACACCT
CACGTACTCCGTCATTCCTTTGCGACACACCTTCTCGAGAACGGTGCGGATTTACGCGCCATTCAACAGATGCTCGGTCA
TGCGGATTTAGCGACGACGCAAGTGTATACACACGTCAACAAATCGCGTCTACATGATGTGTATCGTAAGCATCACCCTC
GTGCCTAG

Upstream 100 bases:

>100_bases
ACAAAAAAGTGAATAAAAAATGAGGTCAGACATCTTCACAACAGTTTACATAAGTGATATGCTGTAAGCGTATTCAGGTG
AAACGAGGAAGGAGGAGGGT

Downstream 100 bases:

>100_bases
ACACCGAAAAGGAGGAATTTTTTGTGAAGAAGTTTAAACGTATTTTCTTAGTCGTCATGGACTCGGTCGGGATCGGTGAA
GCACCAGATGCCGAACAGTT

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MMRSHIESFLQYMTVEKRMSANTRQAYASDLTQYASTLTQLGVEEWNEVTRSHIVKHIEELSQAGRASSSLRRAVSSIRM
FHHHLKMTGVTTTDPSLYLESPKAEKQLPDTWSQTEVERLLDSVPTSDPLSLRDRAMLELLYGTGMRVSELLGLDLDDLQ
FELGYLQCEGKGERARIIPVSSVAQSFVERYIQQARNGLGGRETEALFLNGRGGRLSRQGFWKMIKRRAKLAGIEKEITP
HVLRHSFATHLLENGADLRAIQQMLGHADLATTQVYTHVNKSRLHDVYRKHHPRA

Sequences:

>Translated_295_residues
MMRSHIESFLQYMTVEKRMSANTRQAYASDLTQYASTLTQLGVEEWNEVTRSHIVKHIEELSQAGRASSSLRRAVSSIRM
FHHHLKMTGVTTTDPSLYLESPKAEKQLPDTWSQTEVERLLDSVPTSDPLSLRDRAMLELLYGTGMRVSELLGLDLDDLQ
FELGYLQCEGKGERARIIPVSSVAQSFVERYIQQARNGLGGRETEALFLNGRGGRLSRQGFWKMIKRRAKLAGIEKEITP
HVLRHSFATHLLENGADLRAIQQMLGHADLATTQVYTHVNKSRLHDVYRKHHPRA
>Mature_295_residues
MMRSHIESFLQYMTVEKRMSANTRQAYASDLTQYASTLTQLGVEEWNEVTRSHIVKHIEELSQAGRASSSLRRAVSSIRM
FHHHLKMTGVTTTDPSLYLESPKAEKQLPDTWSQTEVERLLDSVPTSDPLSLRDRAMLELLYGTGMRVSELLGLDLDDLQ
FELGYLQCEGKGERARIIPVSSVAQSFVERYIQQARNGLGGRETEALFLNGRGGRLSRQGFWKMIKRRAKLAGIEKEITP
HVLRHSFATHLLENGADLRAIQQMLGHADLATTQVYTHVNKSRLHDVYRKHHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=41.4383561643836, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1790244, Length=294, Percent_Identity=35.3741496598639, Blast_Score=194, Evalue=6e-51,
Organism=Escherichia coli, GI1790768, Length=178, Percent_Identity=33.7078651685393, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790767, Length=192, Percent_Identity=29.6875, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33580; Mature: 33580

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRSHIESFLQYMTVEKRMSANTRQAYASDLTQYASTLTQLGVEEWNEVTRSHIVKHIEE
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQAGRASSSLRRAVSSIRMFHHHLKMTGVTTTDPSLYLESPKAEKQLPDTWSQTEVERL
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHCCCCCCHHHHHHHH
LDSVPTSDPLSLRDRAMLELLYGTGMRVSELLGLDLDDLQFELGYLQCEGKGERARIIPV
HHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHCEEEECCCCCCEEEEEH
SSVAQSFVERYIQQARNGLGGRETEALFLNGRGGRLSRQGFWKMIKRRAKLAGIEKEITP
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
HVLRHSFATHLLENGADLRAIQQMLGHADLATTQVYTHVNKSRLHDVYRKHHPRA
HHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMRSHIESFLQYMTVEKRMSANTRQAYASDLTQYASTLTQLGVEEWNEVTRSHIVKHIEE
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQAGRASSSLRRAVSSIRMFHHHLKMTGVTTTDPSLYLESPKAEKQLPDTWSQTEVERL
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHCCCCCCHHHHHHHH
LDSVPTSDPLSLRDRAMLELLYGTGMRVSELLGLDLDDLQFELGYLQCEGKGERARIIPV
HHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHCEEEECCCCCCEEEEEH
SSVAQSFVERYIQQARNGLGGRETEALFLNGRGGRLSRQGFWKMIKRRAKLAGIEKEITP
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
HVLRHSFATHLLENGADLRAIQQMLGHADLATTQVYTHVNKSRLHDVYRKHHPRA
HHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10537218; 10498718 [H]