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The map label for this gene is yclF [H]

Identifier: 229916031

GI number: 229916031

Start: 267490

End: 268983

Strand: Direct

Name: yclF [H]

Synonym: EAT1b_0299

Alternate gene names: 229916031

Gene position: 267490-268983 (Clockwise)

Preceding gene: 229916030

Following gene: 229916033

Centisome position: 8.92

GC content: 49.46

Gene sequence:

>1494_bases
ATGGAAAGGATCGATAAACAGACAATCGTGGACAGTGTTCCACAAAAAGGATTCTTCGGACAACCGAAAGGGTTGTTCAC
TTTATTCTTCACTGAGTTTTGGGAACGTTTCTCGTACTATGGCATGCGGGCCATCCTCGTATTCTATATGTACTATGAAG
TCTCTGAGGGAGGACTCGGTCTAGACCGAAACGTCGCACTCTCAATCATGTCCGTCTATGGCGCGCTCGTTTATATGTCT
GGGGTCATTGGGGGATGGCTTGCAGACCGGATTTTCGGGACGTCTCGCGCGGTATTCTACGGTGGTGTGTTCATCATGCT
CGGACACATCGTCCTCTCGATTCCAGGTAGTGTCGTCTTCTTGTTCATCTCGATGGCGTTGATCGTCATTGGTACCGGAT
TATTGAAACCAAACGTATCAAGTATCGTCGGAGACATGTACAGCGAGACGGATCGCCGTCGTGACGCTGGATTCAGTATC
TTCTACATGGGTATCAACTTGGGTGCGTTCATTTCACCACTCATCGTCGGTCAAGTACAAAAAGACTATGGATTCCACTG
GGGCTTTGCGCTCGCGGCAATCGGGATGTTCGTTGGACTCGTCGTCTTCGTATTGACACGAAAAACGAACCTCGGCTTAG
CTGGTTCGTATGTACCGAATCCGTTGACGCCTGATGAGAAAAAGAAAACGATAAAAATCGTCAGCATCGTCACCATTGGA
ATCGCTGTTTTACTCGCAATCTTGATTCCACTTGGATGGTTCACAATCAATACGTTCATCTCACTCGTCGGAGTGTTCGG
TATCGCGATTCCGACCATCTACTTCATTATCATGTATCGTAGTCCGAAAACGACTGAGGTCGAGCGTTCGCGAATCATCG
CCTACATTCCGCTCTTCATCGCCTCCGTCATGTTCTGGGCAATCCAAGAGCAAGGCGCAACGATTTTAGCGAGCTATGCC
GATACACGGACTGACTTAGAGTTCTTTGGATTCACGTTGTCACCAGCGTGGTTCCAATCACTGAACCCACTGTTCATCAT
CTTACTGGCACCGGTCTTCGCTTGGTTATGGGTCCGACTTGGTGACCGCGAACCGAGCATTCCGACGAAGTTTGCTTTCG
GGATCTTGTTTGCGGGGATCAGTTTCTTGGTCATCCTGCTCCCTGCATACTTCAGTGGTCCGGATGCCCTCGTCAGCCCA
CTCTGGCTCGTCTTGAGCTATTTCATCGTCGTTTTAGGAGAACTCAGTTTGTCACCGGTCGGTTTGTCGGCCACGACAAA
ACTCGCACCAGCTGCCTTCTCGGCTCAAACGATGTCGCTCTGGTTCTTATCAAACGCTGCTGCACAAGGGATCAACGCAC
AGCTCGTCAAGTTCTACACACCTGAGAATGAGACGCTATACTTCGGGATTATCGGTGGCGTCGCCATCGTCTTAAGTTTG
ATTCTGTTCGCACTCGCACCAAAAATCAAAGTGTACATGCGTGGAATCCATTAA

Upstream 100 bases:

>100_bases
TCATTCTTTTCATCTTTATTAAAATTTGAAATTATCATTCAATTCACTTTACAATCATAATAATCCTTTTTATGATAAAA
CGGTTAAGGAGGGATCTTTC

Downstream 100 bases:

>100_bases
TCATCAAAAACGCCAGCCGATTGAATCGGCTGGCGTCATTTTTATTTTCGCACTTGAATGAGTGACAAGTAGCGATCGAT
CATATTGTGGTTAAAGTAGT

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MERIDKQTIVDSVPQKGFFGQPKGLFTLFFTEFWERFSYYGMRAILVFYMYYEVSEGGLGLDRNVALSIMSVYGALVYMS
GVIGGWLADRIFGTSRAVFYGGVFIMLGHIVLSIPGSVVFLFISMALIVIGTGLLKPNVSSIVGDMYSETDRRRDAGFSI
FYMGINLGAFISPLIVGQVQKDYGFHWGFALAAIGMFVGLVVFVLTRKTNLGLAGSYVPNPLTPDEKKKTIKIVSIVTIG
IAVLLAILIPLGWFTINTFISLVGVFGIAIPTIYFIIMYRSPKTTEVERSRIIAYIPLFIASVMFWAIQEQGATILASYA
DTRTDLEFFGFTLSPAWFQSLNPLFIILLAPVFAWLWVRLGDREPSIPTKFAFGILFAGISFLVILLPAYFSGPDALVSP
LWLVLSYFIVVLGELSLSPVGLSATTKLAPAAFSAQTMSLWFLSNAAAQGINAQLVKFYTPENETLYFGIIGGVAIVLSL
ILFALAPKIKVYMRGIH

Sequences:

>Translated_497_residues
MERIDKQTIVDSVPQKGFFGQPKGLFTLFFTEFWERFSYYGMRAILVFYMYYEVSEGGLGLDRNVALSIMSVYGALVYMS
GVIGGWLADRIFGTSRAVFYGGVFIMLGHIVLSIPGSVVFLFISMALIVIGTGLLKPNVSSIVGDMYSETDRRRDAGFSI
FYMGINLGAFISPLIVGQVQKDYGFHWGFALAAIGMFVGLVVFVLTRKTNLGLAGSYVPNPLTPDEKKKTIKIVSIVTIG
IAVLLAILIPLGWFTINTFISLVGVFGIAIPTIYFIIMYRSPKTTEVERSRIIAYIPLFIASVMFWAIQEQGATILASYA
DTRTDLEFFGFTLSPAWFQSLNPLFIILLAPVFAWLWVRLGDREPSIPTKFAFGILFAGISFLVILLPAYFSGPDALVSP
LWLVLSYFIVVLGELSLSPVGLSATTKLAPAAFSAQTMSLWFLSNAAAQGINAQLVKFYTPENETLYFGIIGGVAIVLSL
ILFALAPKIKVYMRGIH
>Mature_497_residues
MERIDKQTIVDSVPQKGFFGQPKGLFTLFFTEFWERFSYYGMRAILVFYMYYEVSEGGLGLDRNVALSIMSVYGALVYMS
GVIGGWLADRIFGTSRAVFYGGVFIMLGHIVLSIPGSVVFLFISMALIVIGTGLLKPNVSSIVGDMYSETDRRRDAGFSI
FYMGINLGAFISPLIVGQVQKDYGFHWGFALAAIGMFVGLVVFVLTRKTNLGLAGSYVPNPLTPDEKKKTIKIVSIVTIG
IAVLLAILIPLGWFTINTFISLVGVFGIAIPTIYFIIMYRSPKTTEVERSRIIAYIPLFIASVMFWAIQEQGATILASYA
DTRTDLEFFGFTLSPAWFQSLNPLFIILLAPVFAWLWVRLGDREPSIPTKFAFGILFAGISFLVILLPAYFSGPDALVSP
LWLVLSYFIVVLGELSLSPVGLSATTKLAPAAFSAQTMSLWFLSNAAAQGINAQLVKFYTPENETLYFGIIGGVAIVLSL
ILFALAPKIKVYMRGIH

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI226371746, Length=351, Percent_Identity=28.4900284900285, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI4827008, Length=407, Percent_Identity=27.027027027027, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI226371748, Length=342, Percent_Identity=27.7777777777778, Blast_Score=100, Evalue=5e-21,
Organism=Escherichia coli, GI1790572, Length=463, Percent_Identity=30.0215982721382, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI1787922, Length=497, Percent_Identity=28.9738430583501, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1786927, Length=415, Percent_Identity=30.8433734939759, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1789911, Length=499, Percent_Identity=27.0541082164329, Blast_Score=194, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI71987453, Length=384, Percent_Identity=26.0416666666667, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17569141, Length=357, Percent_Identity=24.3697478991597, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17541704, Length=396, Percent_Identity=25, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322946, Length=474, Percent_Identity=22.7848101265823, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24639585, Length=366, Percent_Identity=26.775956284153, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24639581, Length=366, Percent_Identity=26.775956284153, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24639583, Length=366, Percent_Identity=26.775956284153, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28571102, Length=223, Percent_Identity=30.0448430493274, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28571100, Length=223, Percent_Identity=30.0448430493274, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28571098, Length=223, Percent_Identity=30.0448430493274, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 54747; Mature: 54747

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50850 MFS ; PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCHHHHHHCCCC
>Mature Secondary Structure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HHHHHCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]