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The map label for this gene is scoA [H]

Identifier: 229586934

GI number: 229586934

Start: 859213

End: 859854

Strand: Direct

Name: scoA [H]

Synonym: RAF_ORF0820

Alternate gene names: 229586934

Gene position: 859213-859854 (Clockwise)

Preceding gene: 229586931

Following gene: 229586935

Centisome position: 67.2

GC content: 35.05

Gene sequence:

>642_bases
ATGACTATAATGTCGGGCGGATTCGGTCTATGCGGTATTCCTGAAAATTTAATAAATGCACTTCTTAAAAGCAATGTTCA
AAATTTAACAGTTATAAGCAATAATTGCGGTGTTGACAACTTCGGACTTGGGCTTCTTCTTCAAACTAAACAAATAAAAA
AAATGATTTCTTCGTATGTCGGAGAAAATAAGATTTTTGAGCAACAATATCTTGATAAGGTTTTAGAGCTTGAGCTAAAC
CCACAAGGAACTTTAGCTGAACGAATTAGGGCTGCTTGTATGGGAATTCCGGCTTTTTATACTAAAACAGGTATAGGTAC
AATTGTAGAGGAAGGTAAAGAAACAAAGGAGTTTAACGGCAAAAAATATATAATGGAAACTGCCCTTCAAGCTGACCTTA
CTATTACTAAAGGCTTTAAAGCTGATAAAAGCGGCAACGTGATTTATAATAAAACTGCACGAAATTTTAATGCAGTCATG
GCAGGTGCCGCTAAAGTTACAGTTTGTGAAGTAGAGGAAATAGTTAAGGTGGGAGAGCTTGACCCTAACAATATTCACAC
ACCTAATATTTTCATACAGCGATTAATAGTAGGTGAAAAATATGAGAAACGTATTGAGCAATTAACTGTCAGGGAAAAAT
AA

Upstream 100 bases:

>100_bases
TCCTAATGTCTTAAATAATAGATATTAAATAATTTAAAATTTATGAATAAAAAATCTATCCTTCGGCTGAAGCTGCTCTT
GAAGACTTCTTTATGACAGC

Downstream 100 bases:

>100_bases
GATATGCCTTGGAGCAAAGAAGAAATTTATCAAATAACCGCAGAGGAACTTAAAGACGGATTATATGTCAATCTTGGTAT
AGGTATGCCTACGCATGTAG

Product: Succinyl-CoA:3-ketoacid-coenzyme A transferase

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTIMSGGFGLCGIPENLINALLKSNVQNLTVISNNCGVDNFGLGLLLQTKQIKKMISSYVGENKIFEQQYLDKVLELELN
PQGTLAERIRAACMGIPAFYTKTGIGTIVEEGKETKEFNGKKYIMETALQADLTITKGFKADKSGNVIYNKTARNFNAVM
AGAAKVTVCEVEEIVKVGELDPNNIHTPNIFIQRLIVGEKYEKRIEQLTVREK

Sequences:

>Translated_213_residues
MTIMSGGFGLCGIPENLINALLKSNVQNLTVISNNCGVDNFGLGLLLQTKQIKKMISSYVGENKIFEQQYLDKVLELELN
PQGTLAERIRAACMGIPAFYTKTGIGTIVEEGKETKEFNGKKYIMETALQADLTITKGFKADKSGNVIYNKTARNFNAVM
AGAAKVTVCEVEEIVKVGELDPNNIHTPNIFIQRLIVGEKYEKRIEQLTVREK
>Mature_212_residues
TIMSGGFGLCGIPENLINALLKSNVQNLTVISNNCGVDNFGLGLLLQTKQIKKMISSYVGENKIFEQQYLDKVLELELNP
QGTLAERIRAACMGIPAFYTKTGIGTIVEEGKETKEFNGKKYIMETALQADLTITKGFKADKSGNVIYNKTARNFNAVMA
GAAKVTVCEVEEIVKVGELDPNNIHTPNIFIQRLIVGEKYEKRIEQLTVREK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=230, Percent_Identity=58.2608695652174, Blast_Score=283, Evalue=8e-77,
Organism=Homo sapiens, GI11545841, Length=227, Percent_Identity=55.0660792951542, Blast_Score=254, Evalue=4e-68,
Organism=Escherichia coli, GI1788551, Length=200, Percent_Identity=41, Blast_Score=170, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17531517, Length=225, Percent_Identity=53.3333333333333, Blast_Score=244, Evalue=2e-65,
Organism=Drosophila melanogaster, GI21358325, Length=228, Percent_Identity=52.6315789473684, Blast_Score=240, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24655794, Length=228, Percent_Identity=52.6315789473684, Blast_Score=240, Evalue=4e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 23567; Mature: 23436

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIMSGGFGLCGIPENLINALLKSNVQNLTVISNNCGVDNFGLGLLLQTKQIKKMISSYV
CEEECCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHEEEHHHHHHHHHHHH
GENKIFEQQYLDKVLELELNPQGTLAERIRAACMGIPAFYTKTGIGTIVEEGKETKEFNG
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHCCHHHHHHCCCHHHHCCC
KKYIMETALQADLTITKGFKADKSGNVIYNKTARNFNAVMAGAAKVTVCEVEEIVKVGEL
HHHHHHHHHHHCEEEECCCCCCCCCCEEEECCCCCHHHHHHCCCEEEHHHHHHHHHHCCC
DPNNIHTPNIFIQRLIVGEKYEKRIEQLTVREK
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TIMSGGFGLCGIPENLINALLKSNVQNLTVISNNCGVDNFGLGLLLQTKQIKKMISSYV
EEECCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHEEEHHHHHHHHHHHH
GENKIFEQQYLDKVLELELNPQGTLAERIRAACMGIPAFYTKTGIGTIVEEGKETKEFNG
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHCCHHHHHHCCCHHHHCCC
KKYIMETALQADLTITKGFKADKSGNVIYNKTARNFNAVMAGAAKVTVCEVEEIVKVGEL
HHHHHHHHHHHCEEEECCCCCCCCCCEEEECCCCCHHHHHHCCCEEEHHHHHHHHHHCCC
DPNNIHTPNIFIQRLIVGEKYEKRIEQLTVREK
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]