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The map label for this gene is iscU [H]

Identifier: 229586811

GI number: 229586811

Start: 708948

End: 709343

Strand: Direct

Name: iscU [H]

Synonym: RAF_ORF0677

Alternate gene names: 229586811

Gene position: 708948-709343 (Clockwise)

Preceding gene: 229586810

Following gene: 229586812

Centisome position: 55.45

GC content: 37.12

Gene sequence:

>396_bases
ATGGCTTATAGCAAAAAAGTGATAGATCATTATGAAAATCCTCGTAATGTTGGATCGCTTGATAAAGAAAATAAAAATGT
TGGTACAGGACTAGTTGGAGCTCCTGCTTGCGGTGACGTTATGAAGTTACAAATCGCAGTTGATGATGACGGGATTATTA
CAGATGCTAAATTTAAAACATTCGGCTGCGGTTCAGCTATTGCTTCAAGTTCTTTAGTAACGGAGTGGGTTAAAGGAAGA
TCGGTAGAAGATGCCGAGACTATTAAAAATACCGAAATAGCAAAAGAATTGTCACTTCCACCGGTCAAATTACATTGCTC
ACTACTTGCTGAAGATGCAATAAAAGCAGCTATAGCCGATTACAAACAGAAAAAAGAAAGCAAAAAAGACTCTTAA

Upstream 100 bases:

>100_bases
TCCTGAGATTGCTTCGTCAAAACTTGCAGTTTTTCCTCGCAATGACGGCTCAGGTATTCACGCAAGTATAACATACAAAA
CCAAATTTTAGGGAATAACA

Downstream 100 bases:

>100_bases
AATATGAAAAATGTTATTTCATTAACCGATTCTGCTGCAAAACAAGTAAAATTGCTAATAGAAAAACGCGCCAAGCCTAC
CTTTGGTATTAGGGTAGGGG

Product: scaffold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 130

Protein sequence:

>131_residues
MAYSKKVIDHYENPRNVGSLDKENKNVGTGLVGAPACGDVMKLQIAVDDDGIITDAKFKTFGCGSAIASSSLVTEWVKGR
SVEDAETIKNTEIAKELSLPPVKLHCSLLAEDAIKAAIADYKQKKESKKDS

Sequences:

>Translated_131_residues
MAYSKKVIDHYENPRNVGSLDKENKNVGTGLVGAPACGDVMKLQIAVDDDGIITDAKFKTFGCGSAIASSSLVTEWVKGR
SVEDAETIKNTEIAKELSLPPVKLHCSLLAEDAIKAAIADYKQKKESKKDS
>Mature_130_residues
AYSKKVIDHYENPRNVGSLDKENKNVGTGLVGAPACGDVMKLQIAVDDDGIITDAKFKTFGCGSAIASSSLVTEWVKGRS
VEDAETIKNTEIAKELSLPPVKLHCSLLAEDAIKAAIADYKQKKESKKDS

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=127, Percent_Identity=82.6771653543307, Blast_Score=221, Evalue=9e-59,
Organism=Homo sapiens, GI24307953, Length=126, Percent_Identity=81.7460317460317, Blast_Score=216, Evalue=6e-57,
Organism=Escherichia coli, GI1788878, Length=128, Percent_Identity=78.125, Blast_Score=218, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI17543474, Length=127, Percent_Identity=74.8031496062992, Blast_Score=201, Evalue=8e-53,
Organism=Saccharomyces cerevisiae, GI6325122, Length=126, Percent_Identity=74.6031746031746, Blast_Score=196, Evalue=8e-52,
Organism=Saccharomyces cerevisiae, GI6324800, Length=124, Percent_Identity=75.8064516129032, Blast_Score=193, Evalue=8e-51,
Organism=Drosophila melanogaster, GI21355597, Length=126, Percent_Identity=76.1904761904762, Blast_Score=206, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011339
- InterPro:   IPR002871 [H]

Pfam domain/function: PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 14070; Mature: 13939

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSKKVIDHYENPRNVGSLDKENKNVGTGLVGAPACGDVMKLQIAVDDDGIITDAKFKT
CCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEECCCCCC
FGCGSAIASSSLVTEWVKGRSVEDAETIKNTEIAKELSLPPVKLHCSLLAEDAIKAAIAD
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
YKQKKESKKDS
HHHHHHCCCCC
>Mature Secondary Structure 
AYSKKVIDHYENPRNVGSLDKENKNVGTGLVGAPACGDVMKLQIAVDDDGIITDAKFKT
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEECCCCCC
FGCGSAIASSSLVTEWVKGRSVEDAETIKNTEIAKELSLPPVKLHCSLLAEDAIKAAIAD
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
YKQKKESKKDS
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]