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The map label for this gene is iscA2 [C]

Identifier: 229586812

GI number: 229586812

Start: 709347

End: 709679

Strand: Direct

Name: iscA2 [C]

Synonym: RAF_ORF0678

Alternate gene names: 229586812

Gene position: 709347-709679 (Clockwise)

Preceding gene: 229586811

Following gene: 229586814

Centisome position: 55.48

GC content: 38.44

Gene sequence:

>333_bases
ATGAAAAATGTTATTTCATTAACCGATTCTGCTGCAAAACAAGTAAAATTGCTAATAGAAAAACGCGCCAAGCCTACCTT
TGGTATTAGGGTAGGGGTTAAGTCAGGCGGTTGTGCCGGTCAGACTTATTACGTGGAATATGCCGATAGTAAAAATCAAT
TCGATGAAGTAGTTGAAGAAAAGGGCGTACGGATACTAATCGACCCAAAGGCATTAATGTATATTCTAGGTTCTGAAATG
GACTATGTAGAGACTAAATTCAAATCCCAATTCACTTTCACCAATCCTAATGAAAAAGCTAATTGCGGCTGCGGCAAATC
TTTTAGCGTGTAA

Upstream 100 bases:

>100_bases
ACCGGTCAAATTACATTGCTCACTACTTGCTGAAGATGCAATAAAAGCAGCTATAGCCGATTACAAACAGAAAAAAGAAA
GCAAAAAAGACTCTTAAAAT

Downstream 100 bases:

>100_bases
CACTTTAGAATCAATAAAGGTTTTAAAATATGTTTAACTGGGTTTATAATAAAAGATTCTCTTATCCTTCACCTAATATT
GAAAGCTTACGAAAAGCACT

Product: Iron-sulfur cluster assembly accessory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MKNVISLTDSAAKQVKLLIEKRAKPTFGIRVGVKSGGCAGQTYYVEYADSKNQFDEVVEEKGVRILIDPKALMYILGSEM
DYVETKFKSQFTFTNPNEKANCGCGKSFSV

Sequences:

>Translated_110_residues
MKNVISLTDSAAKQVKLLIEKRAKPTFGIRVGVKSGGCAGQTYYVEYADSKNQFDEVVEEKGVRILIDPKALMYILGSEM
DYVETKFKSQFTFTNPNEKANCGCGKSFSV
>Mature_110_residues
MKNVISLTDSAAKQVKLLIEKRAKPTFGIRVGVKSGGCAGQTYYVEYADSKNQFDEVVEEKGVRILIDPKALMYILGSEM
DYVETKFKSQFTFTNPNEKANCGCGKSFSV

Specific function: Unknown

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI52426768, Length=109, Percent_Identity=44.0366972477064, Blast_Score=104, Evalue=1e-23,
Organism=Homo sapiens, GI160420328, Length=107, Percent_Identity=33.6448598130841, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788877, Length=106, Percent_Identity=43.3962264150943, Blast_Score=102, Evalue=5e-24,
Organism=Escherichia coli, GI1786351, Length=106, Percent_Identity=41.5094339622642, Blast_Score=98, Evalue=1e-22,
Organism=Escherichia coli, GI1787974, Length=106, Percent_Identity=33.9622641509434, Blast_Score=77, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193209025, Length=109, Percent_Identity=44.0366972477064, Blast_Score=111, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI25146411, Length=109, Percent_Identity=44.0366972477064, Blast_Score=111, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6323001, Length=107, Percent_Identity=46.7289719626168, Blast_Score=105, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24642263, Length=110, Percent_Identity=44.5454545454545, Blast_Score=106, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 12201; Mature: 12201

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVISLTDSAAKQVKLLIEKRAKPTFGIRVGVKSGGCAGQTYYVEYADSKNQFDEVVEE
CCCEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHH
KGVRILIDPKALMYILGSEMDYVETKFKSQFTFTNPNEKANCGCGKSFSV
CCCEEEECCHHEEHHHCCCCCHHHHHHCCEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKNVISLTDSAAKQVKLLIEKRAKPTFGIRVGVKSGGCAGQTYYVEYADSKNQFDEVVEE
CCCEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHH
KGVRILIDPKALMYILGSEMDYVETKFKSQFTFTNPNEKANCGCGKSFSV
CCCEEEECCHHEEHHHCCCCCHHHHHHCCEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]