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The map label for this gene is yleA [C]

Identifier: 229586694

GI number: 229586694

Start: 567132

End: 568397

Strand: Direct

Name: yleA [C]

Synonym: RAF_ORF0541

Alternate gene names: 229586694

Gene position: 567132-568397 (Clockwise)

Preceding gene: 229586693

Following gene: 229586695

Centisome position: 44.36

GC content: 35.62

Gene sequence:

>1266_bases
GTGGGGAATATTATTGTGAGCAATAATTTAAGACAAAACGTAGTAACATTTGGCTGTAGACTTAATATTTACGAAAGTGA
GATAATACGAAAAAACTTGGAATTGTCGGGTATCGATAATGTAGCAATATTCAATACTTGTGCGGTAACTAAAGCAGCTG
AGAAACAAGCAAGACAAGCTATACGCAAGGCTAAAAAAAATAATCCTGATTTAAAAATTATTGTTACCGGCTGTAGTGCT
CAAACAAGTCCGCAAATGTACGGTAATATGCCGGAAGTTGACAAAGTTATAGGTAATGAAGAGAAGTTATTACCTAATTA
CTACCAAATTACCGATGCAAAAATAACAGTTAACGATATAATGTCGGTGAAAGAGACGGCAAGTCATTTAGTAAGTAGCT
TTGACTGTAAGTCTCGTGCTTTTATTCAGGTACAAAACGGTTGTGATCATTTTTGTACTTTCTGTATTATCCCTTATGGT
AGAGGAAAAAGTAGATCAGTAGCAATAGGAGCTATAGTAGAGCAGGTAAAGCATTTGGTATTAAACGGCTTTAAAGAAGT
AGTTTTTACCGGTGTCGATGTCACGGCTTATGGTAGTGATTTGCCAGGAAGTCCAACATTCGCACAAATGATTAAACGAG
TGTTGAATTTAGTCCCTGAATTAAAGAGGCTTAGATTATCTTCAATAGATGTTGCAGAAATAGATGATGAACTTTTTGAG
CTTATAGCTTATAGTGAAAGGATAATGCCGCATTTTCATATTAGCTTGCAAGCAGGTGATGATATGATATTAAAACGTAT
GAAAAGACGTCATAATAGAGCAAGCGTAATAGAGTTTTGTCGGAAGCTGCGGGCAATAAGACCGGAAGTATCTTTTGGTG
CGGATATTATAGCTGGTTTCCCGACTGAAACCCCTGAAATGTTTGAAAATACAAGACAATTAATTTCAGAAGCGGAATTA
CAATATTTACATGTTTTTCCTTATTCGGAAAGAGAAGGAACGCCTGCAGCACGTATGCCACAAGTACCTAAAAATATAAG
AAAAGAAAGGGCAGCAATTTTAAGGCAAGAAGGGCAAAACCAGTTGACCGAATTCTTTAAAAAACATATAGGACAGAAAG
TGGAGTTATTAGTAGAGAATAATAATATTGCCCATACCGAAAATTTTATTCCGGTAAAGCTAGATAAACCTTTAGAAATA
GGGCAGATATTTAAAGCGAAGTTGGTGGCGATAGAAGAGAATTATATGAAGTGTATGTTGGTTTAA

Upstream 100 bases:

>100_bases
ATTCATTCACCAAGTACTATAGTCTTTAAGCACGGTAACCTTACTATGAAAGAAGAAAACGGTAATATAATAATGCAAGG
GGCAGCTACGCTTGTAGCAC

Downstream 100 bases:

>100_bases
CGTCATTGCAGGGAGGTATTGTTGTGTAGATACTGAAGGTCGTCATTGCGAGGAGCCGTAGGTGACGCGGCAATCCAGAA
AATAATTAAAAAAATTCTGA

Product: MiaB-like tRNA modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MGNIIVSNNLRQNVVTFGCRLNIYESEIIRKNLELSGIDNVAIFNTCAVTKAAEKQARQAIRKAKKNNPDLKIIVTGCSA
QTSPQMYGNMPEVDKVIGNEEKLLPNYYQITDAKITVNDIMSVKETASHLVSSFDCKSRAFIQVQNGCDHFCTFCIIPYG
RGKSRSVAIGAIVEQVKHLVLNGFKEVVFTGVDVTAYGSDLPGSPTFAQMIKRVLNLVPELKRLRLSSIDVAEIDDELFE
LIAYSERIMPHFHISLQAGDDMILKRMKRRHNRASVIEFCRKLRAIRPEVSFGADIIAGFPTETPEMFENTRQLISEAEL
QYLHVFPYSEREGTPAARMPQVPKNIRKERAAILRQEGQNQLTEFFKKHIGQKVELLVENNNIAHTENFIPVKLDKPLEI
GQIFKAKLVAIEENYMKCMLV

Sequences:

>Translated_421_residues
MGNIIVSNNLRQNVVTFGCRLNIYESEIIRKNLELSGIDNVAIFNTCAVTKAAEKQARQAIRKAKKNNPDLKIIVTGCSA
QTSPQMYGNMPEVDKVIGNEEKLLPNYYQITDAKITVNDIMSVKETASHLVSSFDCKSRAFIQVQNGCDHFCTFCIIPYG
RGKSRSVAIGAIVEQVKHLVLNGFKEVVFTGVDVTAYGSDLPGSPTFAQMIKRVLNLVPELKRLRLSSIDVAEIDDELFE
LIAYSERIMPHFHISLQAGDDMILKRMKRRHNRASVIEFCRKLRAIRPEVSFGADIIAGFPTETPEMFENTRQLISEAEL
QYLHVFPYSEREGTPAARMPQVPKNIRKERAAILRQEGQNQLTEFFKKHIGQKVELLVENNNIAHTENFIPVKLDKPLEI
GQIFKAKLVAIEENYMKCMLV
>Mature_420_residues
GNIIVSNNLRQNVVTFGCRLNIYESEIIRKNLELSGIDNVAIFNTCAVTKAAEKQARQAIRKAKKNNPDLKIIVTGCSAQ
TSPQMYGNMPEVDKVIGNEEKLLPNYYQITDAKITVNDIMSVKETASHLVSSFDCKSRAFIQVQNGCDHFCTFCIIPYGR
GKSRSVAIGAIVEQVKHLVLNGFKEVVFTGVDVTAYGSDLPGSPTFAQMIKRVLNLVPELKRLRLSSIDVAEIDDELFEL
IAYSERIMPHFHISLQAGDDMILKRMKRRHNRASVIEFCRKLRAIRPEVSFGADIIAGFPTETPEMFENTRQLISEAELQ
YLHVFPYSEREGTPAARMPQVPKNIRKERAAILRQEGQNQLTEFFKKHIGQKVELLVENNNIAHTENFIPVKLDKPLEIG
QIFKAKLVAIEENYMKCMLV

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI28872784, Length=392, Percent_Identity=26.530612244898, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI28872782, Length=364, Percent_Identity=26.9230769230769, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI93277076, Length=438, Percent_Identity=25.5707762557078, Blast_Score=136, Evalue=5e-32,
Organism=Escherichia coli, GI1786882, Length=436, Percent_Identity=28.6697247706422, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1787057, Length=388, Percent_Identity=30.1546391752577, Blast_Score=150, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17553146, Length=424, Percent_Identity=26.1792452830189, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71996771, Length=282, Percent_Identity=25.531914893617, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21356207, Length=412, Percent_Identity=28.3980582524272, Blast_Score=165, Evalue=6e-41,
Organism=Drosophila melanogaster, GI19922432, Length=365, Percent_Identity=27.3972602739726, Blast_Score=132, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 47605; Mature: 47474

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNIIVSNNLRQNVVTFGCRLNIYESEIIRKNLELSGIDNVAIFNTCAVTKAAEKQARQA
CCCEEECCCCHHHHEEEEEEEEEHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHH
IRKAKKNNPDLKIIVTGCSAQTSPQMYGNMPEVDKVIGNEEKLLPNYYQITDAKITVNDI
HHHHHCCCCCEEEEEECCCCCCCHHHCCCCCHHHHHHCCCHHCCCCEEEEECCEEEHHHH
MSVKETASHLVSSFDCKSRAFIQVQNGCDHFCTFCIIPYGRGKSRSVAIGAIVEQVKHLV
HHHHHHHHHHHHHCCCCCCEEEEECCCCHHEEHEEEEECCCCCCCCCHHHHHHHHHHHHH
LNGFKEVVFTGVDVTAYGSDLPGSPTFAQMIKRVLNLVPELKRLRLSSIDVAEIDDELFE
HHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LIAYSERIMPHFHISLQAGDDMILKRMKRRHNRASVIEFCRKLRAIRPEVSFGADIIAGF
HHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHEECC
PTETPEMFENTRQLISEAELQYLHVFPYSEREGTPAARMPQVPKNIRKERAAILRQEGQN
CCCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHH
QLTEFFKKHIGQKVELLVENNNIAHTENFIPVKLDKPLEIGQIFKAKLVAIEENYMKCML
HHHHHHHHHCCCEEEEEEECCCEEECCCEEEEEECCCCCHHHHHHHHHHEEECCCEEEEC
V
C
>Mature Secondary Structure 
GNIIVSNNLRQNVVTFGCRLNIYESEIIRKNLELSGIDNVAIFNTCAVTKAAEKQARQA
CCEEECCCCHHHHEEEEEEEEEHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHH
IRKAKKNNPDLKIIVTGCSAQTSPQMYGNMPEVDKVIGNEEKLLPNYYQITDAKITVNDI
HHHHHCCCCCEEEEEECCCCCCCHHHCCCCCHHHHHHCCCHHCCCCEEEEECCEEEHHHH
MSVKETASHLVSSFDCKSRAFIQVQNGCDHFCTFCIIPYGRGKSRSVAIGAIVEQVKHLV
HHHHHHHHHHHHHCCCCCCEEEEECCCCHHEEHEEEEECCCCCCCCCHHHHHHHHHHHHH
LNGFKEVVFTGVDVTAYGSDLPGSPTFAQMIKRVLNLVPELKRLRLSSIDVAEIDDELFE
HHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LIAYSERIMPHFHISLQAGDDMILKRMKRRHNRASVIEFCRKLRAIRPEVSFGADIIAGF
HHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHEECC
PTETPEMFENTRQLISEAELQYLHVFPYSEREGTPAARMPQVPKNIRKERAAILRQEGQN
CCCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHH
QLTEFFKKHIGQKVELLVENNNIAHTENFIPVKLDKPLEIGQIFKAKLVAIEENYMKCML
HHHHHHHHHCCCEEEEEEECCCEEECCCEEEEEECCCCCHHHHHHHHHHEEECCCEEEEC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]