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The map label for this gene is mltE1 [H]

Identifier: 229586672

GI number: 229586672

Start: 537754

End: 539715

Strand: Direct

Name: mltE1 [H]

Synonym: RAF_ORF0509

Alternate gene names: 229586672

Gene position: 537754-539715 (Clockwise)

Preceding gene: 229586671

Following gene: 229586673

Centisome position: 42.06

GC content: 31.04

Gene sequence:

>1962_bases
ATGAAAATCATAATAAAATTGTTAACCTCTATATTGTTGTTATTAGCTTTGAAAGTAAATGCTAATTCTGATGCTGTAGA
TAATGTTAAGCAAGTTTTTACCTATATCGATCAAAAAAATTGGTCACAAGCCGAAGATTTAGCTTTAGAAGTAAATAATA
AAATTTTAACAAAAATTGTACTTTCTCAGAAATATTTAGATAATAAATATTCAGATAATAGTTTTGAACATGTAATAAGG
TTTTTATGCAATAACCCGGATTGGCCTCAAAATAAGCTGCTTGAGGAAATAGCAGAAGAATATCTAAATAATAATACAAA
TAAAAAAGTAATTGTTGATTGGTTTAGTAAACATTCTCCTCTTACCGGCAAAGGTTATAAATTTTATGCAGCAGCTGCAA
GTAGTTTAATCAAAGATCAGAAGATATTACTACCTATTATTAAAGAGGCTTGGGTATACGCCAATTTCACTCCTGAAGAA
GAAAATGCATATTACAATAAGTGGCATAAATATTTAACTGCGAGTGATCATTTAGAGCGAATAGAAGAACATTTATGGAA
AAATGATATTAGATCTGCTGAGCAATCCCTGAAATATGTAGAGCAAGGTTACCGTAATTCTTTTAAAGTCCAAATTGCGA
TTATAGGTAAATCGCCAAATGCTGAAAAGCTTTTTAAAAGTGTTCCTGAAAAATACTATACTTCCGGTTTATTATATCGT
TATTTAGATTTTAAAAAAATGCAAAAGCCGACAAAGGAAATTATTACTTTGTTTAAGAAAGCTAAAAATAACCGTAAACA
TTTTGCTAAATGGTGTCGTATTCAGTCCTATTATGCTCGTGAATTCATCGAGTACAAAGATTTTGCTAATAGCTATAGAA
TGGCAACGCTTCCTTTTGCTACTTGTCCTGAAACTATAAGGGAGCAGGAGTGGCTTGCGGGCTGGCTTTCTTTAAGTTTT
TTAAAAAAGCCTGATCAAGCATTAGTACATTTTAATAAGTTTATTAAAGTTGTTAAGACTCCGATTAGTTTGGCACGTGG
GTTTTATTGGCTCGGTCGTACTTATGCAGCAAAAGGCGATAAGCAAATGGCTAGAAAATTTTACGAGCAGGCAGCTAAAT
ATTCTTTTACCTTTTATGGGCAGGTAGCAAATATTGAATTAAATAGGACAAAGTTAGTTTTACCTTCTATTCCCGTAATA
ACTTCTGAAGAAAGGAAAATTATAGAAAATAAAGAGATTATTAAAGCAATAAGGTTATTGGTTAAATATAATAAAAACTA
CTTAGCCCTTATATATTCCAAAGCAGCAATGAAAAATACTAAAAATTCTGCAGAAATTCAAGTAATTGCGAATATTATTA
AAGCCAATAATAATACTAATCATATGGTTGAGGTGGCAAAAATTGCTGCCCAAAATAATGCTTTTATTCTGGATTGTGCT
TTTCCAACGCCTTATAATCTAGTAGGTTTGCCTATCCCACCTCATTTAACTTATGGAATAATTAGACAAGAATCGGTTTT
TGATCATAAAGCAGTAAGTTATGCAAATGCTATGGGTCTCATGCAACTTATTAAAGGTACTGCTTGTGATACCGCAAGAT
CCATAAATGTTAAATGTAATGTAGCAGACTTAACTAGAAATCCGGTATATAATATTAAACTTGGTGCGCATCATTTCAAA
AAATTATTAGATAATCATAAAGGTTCTTATATTCTATCCATTGCTTCTTACAATGCCGGAAGTCATAATGTAGTAAAATG
GATAGATAGGTTTGGTGATCCAAGGGATATAAAAGATACAAGAAAAGTTATTGACTGGATAGAACTTATACCTTATCGAG
AAACAAGAGATTACGTTCAAAGAGTACTTGAAAATGTTCAGATTTATCGGGTAATCTTAAATAAGAATAGTAGTTTGTAC
TTTAAGCGTGACTTACATGCTTGTGATATAGCAAAAAGTTAA

Upstream 100 bases:

>100_bases
GATTCCTGCTTTCGCGGGAATGACATTAACGAGCCATGCAACAACGCTTTTAGTAGCTCGTAATGACTATTAGGTATCCA
CGCAACAAATCATAAAACTT

Downstream 100 bases:

>100_bases
TTTCTATTAGTGTTTTATTTTGACATATAGTAATATGTAAGTATAACACCGACACTAATTAAAAACTATGAATTAAGGAG
GAGAGTATGAAAAAATTAGA

Product: Soluble lytic murein transglycosylase precursor

Products: 1,6-Anhydrobond [C]

Alternate protein names: Peptidoglycan lytic exotransglycosylase [H]

Number of amino acids: Translated: 653; Mature: 653

Protein sequence:

>653_residues
MKIIIKLLTSILLLLALKVNANSDAVDNVKQVFTYIDQKNWSQAEDLALEVNNKILTKIVLSQKYLDNKYSDNSFEHVIR
FLCNNPDWPQNKLLEEIAEEYLNNNTNKKVIVDWFSKHSPLTGKGYKFYAAAASSLIKDQKILLPIIKEAWVYANFTPEE
ENAYYNKWHKYLTASDHLERIEEHLWKNDIRSAEQSLKYVEQGYRNSFKVQIAIIGKSPNAEKLFKSVPEKYYTSGLLYR
YLDFKKMQKPTKEIITLFKKAKNNRKHFAKWCRIQSYYAREFIEYKDFANSYRMATLPFATCPETIREQEWLAGWLSLSF
LKKPDQALVHFNKFIKVVKTPISLARGFYWLGRTYAAKGDKQMARKFYEQAAKYSFTFYGQVANIELNRTKLVLPSIPVI
TSEERKIIENKEIIKAIRLLVKYNKNYLALIYSKAAMKNTKNSAEIQVIANIIKANNNTNHMVEVAKIAAQNNAFILDCA
FPTPYNLVGLPIPPHLTYGIIRQESVFDHKAVSYANAMGLMQLIKGTACDTARSINVKCNVADLTRNPVYNIKLGAHHFK
KLLDNHKGSYILSIASYNAGSHNVVKWIDRFGDPRDIKDTRKVIDWIELIPYRETRDYVQRVLENVQIYRVILNKNSSLY
FKRDLHACDIAKS

Sequences:

>Translated_653_residues
MKIIIKLLTSILLLLALKVNANSDAVDNVKQVFTYIDQKNWSQAEDLALEVNNKILTKIVLSQKYLDNKYSDNSFEHVIR
FLCNNPDWPQNKLLEEIAEEYLNNNTNKKVIVDWFSKHSPLTGKGYKFYAAAASSLIKDQKILLPIIKEAWVYANFTPEE
ENAYYNKWHKYLTASDHLERIEEHLWKNDIRSAEQSLKYVEQGYRNSFKVQIAIIGKSPNAEKLFKSVPEKYYTSGLLYR
YLDFKKMQKPTKEIITLFKKAKNNRKHFAKWCRIQSYYAREFIEYKDFANSYRMATLPFATCPETIREQEWLAGWLSLSF
LKKPDQALVHFNKFIKVVKTPISLARGFYWLGRTYAAKGDKQMARKFYEQAAKYSFTFYGQVANIELNRTKLVLPSIPVI
TSEERKIIENKEIIKAIRLLVKYNKNYLALIYSKAAMKNTKNSAEIQVIANIIKANNNTNHMVEVAKIAAQNNAFILDCA
FPTPYNLVGLPIPPHLTYGIIRQESVFDHKAVSYANAMGLMQLIKGTACDTARSINVKCNVADLTRNPVYNIKLGAHHFK
KLLDNHKGSYILSIASYNAGSHNVVKWIDRFGDPRDIKDTRKVIDWIELIPYRETRDYVQRVLENVQIYRVILNKNSSLY
FKRDLHACDIAKS
>Mature_653_residues
MKIIIKLLTSILLLLALKVNANSDAVDNVKQVFTYIDQKNWSQAEDLALEVNNKILTKIVLSQKYLDNKYSDNSFEHVIR
FLCNNPDWPQNKLLEEIAEEYLNNNTNKKVIVDWFSKHSPLTGKGYKFYAAAASSLIKDQKILLPIIKEAWVYANFTPEE
ENAYYNKWHKYLTASDHLERIEEHLWKNDIRSAEQSLKYVEQGYRNSFKVQIAIIGKSPNAEKLFKSVPEKYYTSGLLYR
YLDFKKMQKPTKEIITLFKKAKNNRKHFAKWCRIQSYYAREFIEYKDFANSYRMATLPFATCPETIREQEWLAGWLSLSF
LKKPDQALVHFNKFIKVVKTPISLARGFYWLGRTYAAKGDKQMARKFYEQAAKYSFTFYGQVANIELNRTKLVLPSIPVI
TSEERKIIENKEIIKAIRLLVKYNKNYLALIYSKAAMKNTKNSAEIQVIANIIKANNNTNHMVEVAKIAAQNNAFILDCA
FPTPYNLVGLPIPPHLTYGIIRQESVFDHKAVSYANAMGLMQLIKGTACDTARSINVKCNVADLTRNPVYNIKLGAHHFK
KLLDNHKGSYILSIASYNAGSHNVVKWIDRFGDPRDIKDTRKVIDWIELIPYRETRDYVQRVLENVQIYRVILNKNSSLY
FKRDLHACDIAKS

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87082441, Length=170, Percent_Identity=30, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011989
- InterPro:   IPR016026
- InterPro:   IPR008258
- InterPro:   IPR012289
- InterPro:   IPR008939
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 75787; Mature: 75787

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS00037 MYB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIIKLLTSILLLLALKVNANSDAVDNVKQVFTYIDQKNWSQAEDLALEVNNKILTKIV
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHHH
LSQKYLDNKYSDNSFEHVIRFLCNNPDWPQNKLLEEIAEEYLNNNTNKKVIVDWFSKHSP
HHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCC
LTGKGYKFYAAAASSLIKDQKILLPIIKEAWVYANFTPEEENAYYNKWHKYLTASDHLER
CCCCCEEEHHHHHHHHHCCCHHHHHHHHHCEEEECCCCCCCCHHHHHHHHHHCHHHHHHH
IEEHLWKNDIRSAEQSLKYVEQGYRNSFKVQIAIIGKSPNAEKLFKSVPEKYYTSGLLYR
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHCCHHHHHHHHHHH
YLDFKKMQKPTKEIITLFKKAKNNRKHFAKWCRIQSYYAREFIEYKDFANSYRMATLPFA
HHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
TCPETIREQEWLAGWLSLSFLKKPDQALVHFNKFIKVVKTPISLARGFYWLGRTYAAKGD
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
KQMARKFYEQAAKYSFTFYGQVANIELNRTKLVLPSIPVITSEERKIIENKEIIKAIRLL
HHHHHHHHHHHHHCEEEEEEEEEEEEECCEEEEECCCCCEECCHHHHHHHHHHHHHHHHH
VKYNKNYLALIYSKAAMKNTKNSAEIQVIANIIKANNNTNHMVEVAKIAAQNNAFILDCA
HHHCCCEEEEEEEHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEC
FPTPYNLVGLPIPPHLTYGIIRQESVFDHKAVSYANAMGLMQLIKGTACDTARSINVKCN
CCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
VADLTRNPVYNIKLGAHHFKKLLDNHKGSYILSIASYNAGSHNVVKWIDRFGDPRDIKDT
EEECCCCCEEEEEECHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHH
RKVIDWIELIPYRETRDYVQRVLENVQIYRVILNKNSSLYFKRDLHACDIAKS
HHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEECCCCCEEEEECCCHHCCCCC
>Mature Secondary Structure
MKIIIKLLTSILLLLALKVNANSDAVDNVKQVFTYIDQKNWSQAEDLALEVNNKILTKIV
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHHH
LSQKYLDNKYSDNSFEHVIRFLCNNPDWPQNKLLEEIAEEYLNNNTNKKVIVDWFSKHSP
HHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCC
LTGKGYKFYAAAASSLIKDQKILLPIIKEAWVYANFTPEEENAYYNKWHKYLTASDHLER
CCCCCEEEHHHHHHHHHCCCHHHHHHHHHCEEEECCCCCCCCHHHHHHHHHHCHHHHHHH
IEEHLWKNDIRSAEQSLKYVEQGYRNSFKVQIAIIGKSPNAEKLFKSVPEKYYTSGLLYR
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHCCHHHHHHHHHHH
YLDFKKMQKPTKEIITLFKKAKNNRKHFAKWCRIQSYYAREFIEYKDFANSYRMATLPFA
HHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
TCPETIREQEWLAGWLSLSFLKKPDQALVHFNKFIKVVKTPISLARGFYWLGRTYAAKGD
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
KQMARKFYEQAAKYSFTFYGQVANIELNRTKLVLPSIPVITSEERKIIENKEIIKAIRLL
HHHHHHHHHHHHHCEEEEEEEEEEEEECCEEEEECCCCCEECCHHHHHHHHHHHHHHHHH
VKYNKNYLALIYSKAAMKNTKNSAEIQVIANIIKANNNTNHMVEVAKIAAQNNAFILDCA
HHHCCCEEEEEEEHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEC
FPTPYNLVGLPIPPHLTYGIIRQESVFDHKAVSYANAMGLMQLIKGTACDTARSINVKCN
CCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
VADLTRNPVYNIKLGAHHFKKLLDNHKGSYILSIASYNAGSHNVVKWIDRFGDPRDIKDT
EEECCCCCEEEEEECHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHH
RKVIDWIELIPYRETRDYVQRVLENVQIYRVILNKNSSLYFKRDLHACDIAKS
HHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEECCCCCEEEEECCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]