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The map label for this gene is hupA [H]

Identifier: 229586413

GI number: 229586413

Start: 223648

End: 224064

Strand: Direct

Name: hupA [H]

Synonym: RAF_ORF0204

Alternate gene names: 229586413

Gene position: 223648-224064 (Clockwise)

Preceding gene: 229586410

Following gene: 229586414

Centisome position: 17.49

GC content: 30.7

Gene sequence:

>417_bases
ATGTATATTATTGCCAGTTGTATATATTGTTTTAGAAAAAAACATCAATACATATTAACCTATCAAAGGAGAATTGATTT
TATTATGAGTACACATAACACAAAAGAACCAAAAAAAATGAATAAAACCGAGTTTATAGCATTTATGACCGATCATGGTC
ATAATCATAAACATGCTTCACATAAAACATTAACAAAAGCTGAAGCCGAGAAAGCACTTAATTTAGTTCTTGATAGTGTG
ATTAGTGCTATAAAGAGCCACCATAATATTAATATAACAGGTTTCGGTTCATTTGAAATACATCATAGAAAAGCACGTGA
GGGTCGTAACCCAAAAACCGGAGCAAAAATGCAAATAGATGCTTACAATCAACCTACTTTTAGAGCCGGAAGAAAAATGA
AAGAAGCTTGTAATTAA

Upstream 100 bases:

>100_bases
AAATTAATATAATAACGTATATATTTTAAATTTTGTAAATAACTGGCATTTGCAGTATGTGGGTAGTTTGTTATAATTAA
CTTACATAAAAAATATATTG

Downstream 100 bases:

>100_bases
AAGAAGTAACGTATTTACAGTACTAATAATTTCCGAACCCCGTTACACGCTTGCGGGGTGACACTAGAAAAACCAGCTCA
TGCAATAATGCTCTGCAAAA

Product: DNA-binding protein HU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MYIIASCIYCFRKKHQYILTYQRRIDFIMSTHNTKEPKKMNKTEFIAFMTDHGHNHKHASHKTLTKAEAEKALNLVLDSV
ISAIKSHHNINITGFGSFEIHHRKAREGRNPKTGAKMQIDAYNQPTFRAGRKMKEACN

Sequences:

>Translated_138_residues
MYIIASCIYCFRKKHQYILTYQRRIDFIMSTHNTKEPKKMNKTEFIAFMTDHGHNHKHASHKTLTKAEAEKALNLVLDSV
ISAIKSHHNINITGFGSFEIHHRKAREGRNPKTGAKMQIDAYNQPTFRAGRKMKEACN
>Mature_138_residues
MYIIASCIYCFRKKHQYILTYQRRIDFIMSTHNTKEPKKMNKTEFIAFMTDHGHNHKHASHKTLTKAEAEKALNLVLDSV
ISAIKSHHNINITGFGSFEIHHRKAREGRNPKTGAKMQIDAYNQPTFRAGRKMKEACN

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=99, Percent_Identity=37.3737373737374, Blast_Score=80, Evalue=5e-17,
Organism=Escherichia coli, GI1790433, Length=98, Percent_Identity=33.6734693877551, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1787141, Length=99, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=9e-12,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 16016; Mature: 16016

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIIASCIYCFRKKHQYILTYQRRIDFIMSTHNTKEPKKMNKTEFIAFMTDHGHNHKHAS
CCHHHHHHHHHHHCCHHEEHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCC
HKTLTKAEAEKALNLVLDSVISAIKSHHNINITGFGSFEIHHRKAREGRNPKTGAKMQID
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEHHHHHHCCCCCCCCCEEEEE
AYNQPTFRAGRKMKEACN
CCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MYIIASCIYCFRKKHQYILTYQRRIDFIMSTHNTKEPKKMNKTEFIAFMTDHGHNHKHAS
CCHHHHHHHHHHHCCHHEEHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCC
HKTLTKAEAEKALNLVLDSVISAIKSHHNINITGFGSFEIHHRKAREGRNPKTGAKMQID
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEHHHHHHCCCCCCCCCEEEEE
AYNQPTFRAGRKMKEACN
CCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]