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The map label for this gene is yyaJ [H]

Identifier: 227826712

GI number: 227826712

Start: 267913

End: 269379

Strand: Direct

Name: yyaJ [H]

Synonym: M1425_0304

Alternate gene names: 227826712

Gene position: 267913-269379 (Clockwise)

Preceding gene: 227826709

Following gene: 227826714

Centisome position: 10.27

GC content: 38.51

Gene sequence:

>1467_bases
ATGTATAAGTCTAAAAAATTAACTTTCATAAGATATTTTTATGAATTTATTGATCTAAGTAACCTCATGAGTAATAAGTT
AGATGAATATCTAGCTAGGATAGATAGATTACCAACCTGGGGACTATCATATGCGCTACTATGGGCATTAGGGATAGGGT
ATTTTGCCACCCTATATGATGCAGTATCGAATTTAGGTTACGCTTTACCATTTATCCCTTTCATAAACGCAACTCAAGCT
TCAATTATTGTATCTGTGGGATTAGTAGGTTACATAGTAGGTTCGATGGGATTTGGTATCACTTCAGATAGGATAGGTAG
AAGACCAATACTGATTGTCACGTTTGCGCTTCTAGGAATTGGCAGTTTAGGTATGGGTTTAGCTACTAACTATTTTACGC
TTTTTATTTTTAGAGTACTAGAGGGCATAGGTATCGGAGCAGCTCTCAATTTAGCTATGGTCTATGTTGCAGAGTTTTCT
CCTAGTACGAAAAGGGGAAAATATGCAAATTGGATTTTCATTTCAGGGTGGACAGCAGTGGGGGCAGGTACAGTGGTTGC
AGCGTTCATTGTCACTATTAGCCCTACAATAGGTTGGAGAATAATTTTCCTTTTGCCTGGAGTCTTAGCTCTTATAACTA
CTGTCATTTTAGCTATTTCATCGCCAGAAAGTGTTAGAATATTGGTGAAGAAAGGAAAGATACAAGATGTGGAAAGGATT
GTAAATAGAATGGAAGAGATAAGTATGAGGAGAGCTAAAATGGAATCGCTTCCACAGCCTAAGATAGTTCATTACGAAGA
GATTCCATCCTATAGTCAACTGAAAATACTAAGAGAGCCGAAATATCTTAAGCGTCTAATTTCGCTTACAGTTTTCTGGT
TCTTCATTTACTTTATACAATACACATCCACTGGACTCGGTCCTACATTCGTAAAAGTAGTGGTAGGATTTTCTCCGGCC
CAATATGCAGAGTACATTAGATTATCAGGGTTTGCAGCGATAGGAGCCACCATAATCTCATTTATATTGCTAGGCATAGT
GGAAAGGACTGATAGAAGGTTATTAACCCAGATTGGAGGAATAGGGTTCCTAGTTAGCTCTTTCGTTTCCACTTACTTAT
TGCTCAACAAGGAACTTATAACTTGGTTTATAACATATTTTCTCCTTGAATTCATTCTTAACCCGCCATACCTAGCTGGA
TATTTAATGAGTAGTGAAGCCTTCCCAACGGCAGTTAGATCAACAAGCTTCGCCATAACTGATGGTATAGGGCATTTAGG
TGGAGTTGTTGGGCCTTTGCTCTTATTTCCCTTAATAGGGATAATAGGTCCATTACCAGCATGGATAGTTCTAGGTCTTC
CAGTTCCTTTTGCTGCTGCATTGTTATGGTTTACAATTCCAAACACAGTAGGGGTTAGACTTGAGGAGGTCAATGAAGCT
TACAGAGAGGGTGCTACACAAAGATAA

Upstream 100 bases:

>100_bases
TTTGCCCTTTGCTCTAATTAGGAATTAAACTCATTCGAATTTTGTATCAAATTTCTCTATGATATATATTATTGATAGCT
AATATCTAATTATACAATTT

Downstream 100 bases:

>100_bases
GTCATAGCTAAATAATTATTAGCGAAACTTTAGAGAATTAATAGTGAAAGTTTCTTAAAATTAAATAGTAAACTATATAT
GGAGTCAAAAATATAAGATT

Product: major facilitator superfamily MFS_1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MYKSKKLTFIRYFYEFIDLSNLMSNKLDEYLARIDRLPTWGLSYALLWALGIGYFATLYDAVSNLGYALPFIPFINATQA
SIIVSVGLVGYIVGSMGFGITSDRIGRRPILIVTFALLGIGSLGMGLATNYFTLFIFRVLEGIGIGAALNLAMVYVAEFS
PSTKRGKYANWIFISGWTAVGAGTVVAAFIVTISPTIGWRIIFLLPGVLALITTVILAISSPESVRILVKKGKIQDVERI
VNRMEEISMRRAKMESLPQPKIVHYEEIPSYSQLKILREPKYLKRLISLTVFWFFIYFIQYTSTGLGPTFVKVVVGFSPA
QYAEYIRLSGFAAIGATIISFILLGIVERTDRRLLTQIGGIGFLVSSFVSTYLLLNKELITWFITYFLLEFILNPPYLAG
YLMSSEAFPTAVRSTSFAITDGIGHLGGVVGPLLLFPLIGIIGPLPAWIVLGLPVPFAAALLWFTIPNTVGVRLEEVNEA
YREGATQR

Sequences:

>Translated_488_residues
MYKSKKLTFIRYFYEFIDLSNLMSNKLDEYLARIDRLPTWGLSYALLWALGIGYFATLYDAVSNLGYALPFIPFINATQA
SIIVSVGLVGYIVGSMGFGITSDRIGRRPILIVTFALLGIGSLGMGLATNYFTLFIFRVLEGIGIGAALNLAMVYVAEFS
PSTKRGKYANWIFISGWTAVGAGTVVAAFIVTISPTIGWRIIFLLPGVLALITTVILAISSPESVRILVKKGKIQDVERI
VNRMEEISMRRAKMESLPQPKIVHYEEIPSYSQLKILREPKYLKRLISLTVFWFFIYFIQYTSTGLGPTFVKVVVGFSPA
QYAEYIRLSGFAAIGATIISFILLGIVERTDRRLLTQIGGIGFLVSSFVSTYLLLNKELITWFITYFLLEFILNPPYLAG
YLMSSEAFPTAVRSTSFAITDGIGHLGGVVGPLLLFPLIGIIGPLPAWIVLGLPVPFAAALLWFTIPNTVGVRLEEVNEA
YREGATQR
>Mature_488_residues
MYKSKKLTFIRYFYEFIDLSNLMSNKLDEYLARIDRLPTWGLSYALLWALGIGYFATLYDAVSNLGYALPFIPFINATQA
SIIVSVGLVGYIVGSMGFGITSDRIGRRPILIVTFALLGIGSLGMGLATNYFTLFIFRVLEGIGIGAALNLAMVYVAEFS
PSTKRGKYANWIFISGWTAVGAGTVVAAFIVTISPTIGWRIIFLLPGVLALITTVILAISSPESVRILVKKGKIQDVERI
VNRMEEISMRRAKMESLPQPKIVHYEEIPSYSQLKILREPKYLKRLISLTVFWFFIYFIQYTSTGLGPTFVKVVVGFSPA
QYAEYIRLSGFAAIGATIISFILLGIVERTDRRLLTQIGGIGFLVSSFVSTYLLLNKELITWFITYFLLEFILNPPYLAG
YLMSSEAFPTAVRSTSFAITDGIGHLGGVVGPLLLFPLIGIIGPLPAWIVLGLPVPFAAALLWFTIPNTVGVRLEEVNEA
YREGATQR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI216548223, Length=253, Percent_Identity=23.3201581027668, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI90669191, Length=366, Percent_Identity=25.1366120218579, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI24497497, Length=366, Percent_Identity=25.1366120218579, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI21553331, Length=355, Percent_Identity=25.3521126760563, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI302148518, Length=370, Percent_Identity=23.2432432432432, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1788074, Length=452, Percent_Identity=24.1150442477876, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1788068, Length=483, Percent_Identity=26.7080745341615, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082231, Length=391, Percent_Identity=25.0639386189258, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082159, Length=421, Percent_Identity=26.3657957244656, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786229, Length=354, Percent_Identity=23.1638418079096, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789207, Length=443, Percent_Identity=24.3792325056433, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789312, Length=453, Percent_Identity=25.60706401766, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17555228, Length=402, Percent_Identity=25.3731343283582, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI32565921, Length=361, Percent_Identity=26.8698060941828, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17554160, Length=362, Percent_Identity=23.2044198895028, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17565978, Length=216, Percent_Identity=29.1666666666667, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71985447, Length=362, Percent_Identity=25.1381215469613, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32564663, Length=380, Percent_Identity=24.2105263157895, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI25145172, Length=437, Percent_Identity=22.4256292906178, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17542342, Length=416, Percent_Identity=25.4807692307692, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 54036; Mature: 54036

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKSKKLTFIRYFYEFIDLSNLMSNKLDEYLARIDRLPTWGLSYALLWALGIGYFATLYD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AVSNLGYALPFIPFINATQASIIVSVGLVGYIVGSMGFGITSDRIGRRPILIVTFALLGI
HHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
GSLGMGLATNYFTLFIFRVLEGIGIGAALNLAMVYVAEFSPSTKRGKYANWIFISGWTAV
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCHHH
GAGTVVAAFIVTISPTIGWRIIFLLPGVLALITTVILAISSPESVRILVKKGKIQDVERI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHH
VNRMEEISMRRAKMESLPQPKIVHYEEIPSYSQLKILREPKYLKRLISLTVFWFFIYFIQ
HHHHHHHHHHHHHHHCCCCCCEEEHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
YTSTGLGPTFVKVVVGFSPAQYAEYIRLSGFAAIGATIISFILLGIVERTDRRLLTQIGG
HHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGFLVSSFVSTYLLLNKELITWFITYFLLEFILNPPYLAGYLMSSEAFPTAVRSTSFAIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHCCCCEEE
DGIGHLGGVVGPLLLFPLIGIIGPLPAWIVLGLPVPFAAALLWFTIPNTVGVRLEEVNEA
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHCCCHHCHHHHHHHHH
YREGATQR
HHCCCCCC
>Mature Secondary Structure
MYKSKKLTFIRYFYEFIDLSNLMSNKLDEYLARIDRLPTWGLSYALLWALGIGYFATLYD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AVSNLGYALPFIPFINATQASIIVSVGLVGYIVGSMGFGITSDRIGRRPILIVTFALLGI
HHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
GSLGMGLATNYFTLFIFRVLEGIGIGAALNLAMVYVAEFSPSTKRGKYANWIFISGWTAV
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCHHH
GAGTVVAAFIVTISPTIGWRIIFLLPGVLALITTVILAISSPESVRILVKKGKIQDVERI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHH
VNRMEEISMRRAKMESLPQPKIVHYEEIPSYSQLKILREPKYLKRLISLTVFWFFIYFIQ
HHHHHHHHHHHHHHHCCCCCCEEEHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
YTSTGLGPTFVKVVVGFSPAQYAEYIRLSGFAAIGATIISFILLGIVERTDRRLLTQIGG
HHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGFLVSSFVSTYLLLNKELITWFITYFLLEFILNPPYLAGYLMSSEAFPTAVRSTSFAIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHCCCCEEE
DGIGHLGGVVGPLLLFPLIGIIGPLPAWIVLGLPVPFAAALLWFTIPNTVGVRLEEVNEA
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHCCCHHCHHHHHHHHH
YREGATQR
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]