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The map label for this gene is bcd [H]

Identifier: 227826709

GI number: 227826709

Start: 263560

End: 264672

Strand: Direct

Name: bcd [H]

Synonym: M1425_0301

Alternate gene names: 227826709

Gene position: 263560-264672 (Clockwise)

Preceding gene: 227826708

Following gene: 227826712

Centisome position: 10.1

GC content: 39.44

Gene sequence:

>1113_bases
ATGAGTAAAAATGAGGATGAATTGGAAGAGTACAGAAGTAAGATAAGGGAGTGGATAAGGAATAATGTACCGGAGGAGAT
GAGCTCTAAAGGAGATATGGCTCCTCCTGAGATCTTAAGGGAGTGGCAAAGGAGAATATATGAGGCAGGATATTTAGGGG
TTTCTTGGCCAAAGGAATATGGTGGATGGGGAGAAAATCCGATTAAGGAGATAATAGTTAGAGAGGAGTTCGCCAAGGCA
GGAGTACCTTATGCAACAGTTGGATTAGGAGTATCTGTAGTTGGTCCAGCAATAATTCTCAACGGTACTGAAGAACAGAA
GAGGAAATACATAAGGAGAATACTAACGGCTGAGGATATATGGTGTCAAGGTTTTTCTGAACCACAAGCTGGTTCAGATT
TAGCTGGAATAAAGACTAAAGCTGAGGATAAGGGGGATCACTTTCTAGTTAATGGACAGAAGATATGGAGTAGTTATGCA
CATTTGGCTAACTATTGTCTTCTTCTAACTAGAACTGGTGATGTATCGGAGAGACATAAGGGGCTTACTATGCTTATAGT
TGATATGAAAAGTGAGGGAATAAGAATAAGCCCAATAAAGCAAATTACTGGGAGGTCAGAATTTAACACATTGTATTTTA
GTAACGTAAAGGTTCCTAAGGAGAACGTTGTTGGTAAGGTCGGTGAAGGATGGAAAGTGGCAATGTCCACGCTAAATTAT
GAGAGGCTTAATATAGGAACAATATTATTTACAGTAGAGAGGCTTATAAGGGAATTATCTATTAACAATGAGCAATTGTT
CAATACCGCTGAGGATATAGTAGCACTAAAGTCATTTTATAAGAGGATATTGGAGCGGCTTAAGAAGGGATATGTTGCAG
GTCCAGAGGCTGCAGTGATAAAGTTGGTAGCTTCAGAGGCCATACAGAGAGTTTATGAAAATGCAGTAGCTAATGCTGGA
ATAGAAGGACTAGTAATGGAAAATGGAGCCGAATTTAGACCAGAGATGATATATGGCTTATTAGCCTCTAGAGCTATAAC
AATAGCTGGCGGGACTTCAGAGATATTAAGGAATTTATTAGGAGAGGTTGTTCTAGGATTACCGAAAGGATAA

Upstream 100 bases:

>100_bases
TGGGGAAATTTGATAAGAAGGTTTTAAGGGAAAAATATAGAGATTTCTTTACTAGTGGTAGAAAAGAAAGTATTTAAAGT
GAAGAGGAGGTATTAAAATT

Downstream 100 bases:

>100_bases
AGAAAGAAAATAAAGTTACTAAAAAATTATTCTCCTTTAAATTGTGGTTTTCTTTTCTCCAAGAAAGCTTTTACTCCTTC
TTCCACATCTTTAGTTGTAA

Product: acyl-CoA dehydrogenase domain protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSKNEDELEEYRSKIREWIRNNVPEEMSSKGDMAPPEILREWQRRIYEAGYLGVSWPKEYGGWGENPIKEIIVREEFAKA
GVPYATVGLGVSVVGPAIILNGTEEQKRKYIRRILTAEDIWCQGFSEPQAGSDLAGIKTKAEDKGDHFLVNGQKIWSSYA
HLANYCLLLTRTGDVSERHKGLTMLIVDMKSEGIRISPIKQITGRSEFNTLYFSNVKVPKENVVGKVGEGWKVAMSTLNY
ERLNIGTILFTVERLIRELSINNEQLFNTAEDIVALKSFYKRILERLKKGYVAGPEAAVIKLVASEAIQRVYENAVANAG
IEGLVMENGAEFRPEMIYGLLASRAITIAGGTSEILRNLLGEVVLGLPKG

Sequences:

>Translated_370_residues
MSKNEDELEEYRSKIREWIRNNVPEEMSSKGDMAPPEILREWQRRIYEAGYLGVSWPKEYGGWGENPIKEIIVREEFAKA
GVPYATVGLGVSVVGPAIILNGTEEQKRKYIRRILTAEDIWCQGFSEPQAGSDLAGIKTKAEDKGDHFLVNGQKIWSSYA
HLANYCLLLTRTGDVSERHKGLTMLIVDMKSEGIRISPIKQITGRSEFNTLYFSNVKVPKENVVGKVGEGWKVAMSTLNY
ERLNIGTILFTVERLIRELSINNEQLFNTAEDIVALKSFYKRILERLKKGYVAGPEAAVIKLVASEAIQRVYENAVANAG
IEGLVMENGAEFRPEMIYGLLASRAITIAGGTSEILRNLLGEVVLGLPKG
>Mature_369_residues
SKNEDELEEYRSKIREWIRNNVPEEMSSKGDMAPPEILREWQRRIYEAGYLGVSWPKEYGGWGENPIKEIIVREEFAKAG
VPYATVGLGVSVVGPAIILNGTEEQKRKYIRRILTAEDIWCQGFSEPQAGSDLAGIKTKAEDKGDHFLVNGQKIWSSYAH
LANYCLLLTRTGDVSERHKGLTMLIVDMKSEGIRISPIKQITGRSEFNTLYFSNVKVPKENVVGKVGEGWKVAMSTLNYE
RLNIGTILFTVERLIRELSINNEQLFNTAEDIVALKSFYKRILERLKKGYVAGPEAAVIKLVASEAIQRVYENAVANAGI
EGLVMENGAEFRPEMIYGLLASRAITIAGGTSEILRNLLGEVVLGLPKG

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557231, Length=245, Percent_Identity=34.6938775510204, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI187960098, Length=245, Percent_Identity=34.6938775510204, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI21361497, Length=383, Percent_Identity=29.7650130548303, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI226958412, Length=348, Percent_Identity=26.1494252873563, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4501859, Length=244, Percent_Identity=30.7377049180328, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI226958414, Length=347, Percent_Identity=26.5129682997118, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4557233, Length=338, Percent_Identity=28.9940828402367, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI76496475, Length=351, Percent_Identity=29.0598290598291, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4557235, Length=351, Percent_Identity=29.0598290598291, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI4501857, Length=381, Percent_Identity=23.0971128608924, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI7656849, Length=253, Percent_Identity=24.901185770751, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI48976061, Length=296, Percent_Identity=25.3378378378378, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI211971008, Length=296, Percent_Identity=25.3378378378378, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI38505218, Length=287, Percent_Identity=26.1324041811847, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87081958, Length=241, Percent_Identity=29.4605809128631, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786223, Length=382, Percent_Identity=21.9895287958115, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=377, Percent_Identity=26.790450928382, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17508101, Length=341, Percent_Identity=30.791788856305, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17570075, Length=390, Percent_Identity=27.6923076923077, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17534899, Length=397, Percent_Identity=27.7078085642317, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17506239, Length=250, Percent_Identity=32.8, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI32563615, Length=199, Percent_Identity=36.1809045226131, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17569725, Length=359, Percent_Identity=27.5766016713092, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71990804, Length=226, Percent_Identity=33.1858407079646, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71985184, Length=352, Percent_Identity=26.9886363636364, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71985192, Length=218, Percent_Identity=33.0275229357798, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17505929, Length=216, Percent_Identity=26.3888888888889, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17551932, Length=216, Percent_Identity=26.3888888888889, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71982178, Length=213, Percent_Identity=30.0469483568075, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17533517, Length=231, Percent_Identity=26.4069264069264, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531909, Length=113, Percent_Identity=33.6283185840708, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17534353, Length=204, Percent_Identity=27.9411764705882, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=27.154046997389, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI21356377, Length=389, Percent_Identity=29.0488431876607, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281363737, Length=388, Percent_Identity=29.3814432989691, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24666513, Length=288, Percent_Identity=30.2083333333333, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24660351, Length=257, Percent_Identity=31.5175097276265, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24646207, Length=381, Percent_Identity=26.7716535433071, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI19920834, Length=253, Percent_Identity=28.0632411067194, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 41344; Mature: 41213

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNEDELEEYRSKIREWIRNNVPEEMSSKGDMAPPEILREWQRRIYEAGYLGVSWPKEY
CCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHH
GGWGENPIKEIIVREEFAKAGVPYATVGLGVSVVGPAIILNGTEEQKRKYIRRILTAEDI
CCCCCCHHHHHHHHHHHHHCCCCEEHHHCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHH
WCQGFSEPQAGSDLAGIKTKAEDKGDHFLVNGQKIWSSYAHLANYCLLLTRTGDVSERHK
HHCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHEEEEECCCCHHHHHC
GLTMLIVDMKSEGIRISPIKQITGRSEFNTLYFSNVKVPKENVVGKVGEGWKVAMSTLNY
CEEEEEEEECCCCEEECHHHHHCCCCCCCEEEEECCCCCHHHHCCCCCCCHHHHHHHCCC
ERLNIGTILFTVERLIRELSINNEQLFNTAEDIVALKSFYKRILERLKKGYVAGPEAAVI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
KLVASEAIQRVYENAVANAGIEGLVMENGAEFRPEMIYGLLASRAITIAGGTSEILRNLL
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCEEEEECCHHHHHHHHH
GEVVLGLPKG
HHHHHCCCCC
>Mature Secondary Structure 
SKNEDELEEYRSKIREWIRNNVPEEMSSKGDMAPPEILREWQRRIYEAGYLGVSWPKEY
CCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHH
GGWGENPIKEIIVREEFAKAGVPYATVGLGVSVVGPAIILNGTEEQKRKYIRRILTAEDI
CCCCCCHHHHHHHHHHHHHCCCCEEHHHCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHH
WCQGFSEPQAGSDLAGIKTKAEDKGDHFLVNGQKIWSSYAHLANYCLLLTRTGDVSERHK
HHCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHEEEEECCCCHHHHHC
GLTMLIVDMKSEGIRISPIKQITGRSEFNTLYFSNVKVPKENVVGKVGEGWKVAMSTLNY
CEEEEEEEECCCCEEECHHHHHCCCCCCCEEEEECCCCCHHHHCCCCCCCHHHHHHHCCC
ERLNIGTILFTVERLIRELSINNEQLFNTAEDIVALKSFYKRILERLKKGYVAGPEAAVI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
KLVASEAIQRVYENAVANAGIEGLVMENGAEFRPEMIYGLLASRAITIAGGTSEILRNLL
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCEEEEECCHHHHHHHHH
GEVVLGLPKG
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]