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The map label for this gene is dsbB

Identifier: 227082032

GI number: 227082032

Start: 1988241

End: 1988762

Strand: Direct

Name: dsbB

Synonym: VCM66_1826

Alternate gene names: 227082032

Gene position: 1988241-1988762 (Clockwise)

Preceding gene: 227082031

Following gene: 227082035

Centisome position: 68.74

GC content: 48.85

Gene sequence:

>522_bases
GTGCGTATATTATCCTCCCTTAAAACCTTTTCTCAGTCGCGATTATCTTGGCTGTTGCTGCTGGCATTTGTCGTTTTCTT
TACCTTGTGTGCCATGTACTTTCAACATGTGATGCTACTTGCACCTTGTGTCATGTGTATCTATGAACGTATCGCTATGC
TGGGGATTGGTGTCGCCGCCTTGATTGGCGCAATTGCACCACAAAACCCTGTCGTACGTTGGCTCGGTTTTGCTGCTTGG
GGTGCCAGCAGCTACAAAGGTTTGATGCTGGCGATCGAGCATGTCAACTACCAGTTTAACCCTTCGCCTTTTGCTACTTG
CGATCTGTTTGTCACCTTCCCGGCTTGGGCTCCGCTCAACCAATGGGCTCCCAATCTGTTTGAAGCGTATGGTGACTGTA
GCAAGGTGGTATGGCAGTTTTTGACGCTCTCTATGCCACAGTGGCTTGTCGTTATCTTCGCGGCAAACTTACTCGCATTA
GCGATTTTTGTCGTCGCACAACTGGCTAAAACCTCACGCTAA

Upstream 100 bases:

>100_bases
CTACTGCAAAGTGGCCACTAAATTTCAATTGAAACTGAAACTAATCCAAGATACAAAGCTCTGAGTATTCAGAGCTTTTC
TTTTTAACAAGGATCTATCT

Downstream 100 bases:

>100_bases
GCCAATCGCATCGCTCAATCCGGTTGATAAAAAAGGCGCTTAAAGCGCCTTTTTTACTTTTGTTGTTTCTGCTGTTTAAT
CTCGTATAGGTGCAGGAGCC

Product: disulfide bond formation protein B

Products: NA

Alternate protein names: Disulfide oxidoreductase

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MRILSSLKTFSQSRLSWLLLLAFVVFFTLCAMYFQHVMLLAPCVMCIYERIAMLGIGVAALIGAIAPQNPVVRWLGFAAW
GASSYKGLMLAIEHVNYQFNPSPFATCDLFVTFPAWAPLNQWAPNLFEAYGDCSKVVWQFLTLSMPQWLVVIFAANLLAL
AIFVVAQLAKTSR

Sequences:

>Translated_173_residues
MRILSSLKTFSQSRLSWLLLLAFVVFFTLCAMYFQHVMLLAPCVMCIYERIAMLGIGVAALIGAIAPQNPVVRWLGFAAW
GASSYKGLMLAIEHVNYQFNPSPFATCDLFVTFPAWAPLNQWAPNLFEAYGDCSKVVWQFLTLSMPQWLVVIFAANLLAL
AIFVVAQLAKTSR
>Mature_173_residues
MRILSSLKTFSQSRLSWLLLLAFVVFFTLCAMYFQHVMLLAPCVMCIYERIAMLGIGVAALIGAIAPQNPVVRWLGFAAW
GASSYKGLMLAIEHVNYQFNPSPFATCDLFVTFPAWAPLNQWAPNLFEAYGDCSKVVWQFLTLSMPQWLVVIFAANLLAL
AIFVVAQLAKTSR

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family

Homologues:

Organism=Escherichia coli, GI1787433, Length=171, Percent_Identity=47.953216374269, Blast_Score=165, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBB_VIBCH (Q9KQU6)

Other databases:

- EMBL:   AE003852
- PIR:   H82141
- RefSeq:   NP_231536.1
- ProteinModelPortal:   Q9KQU6
- SMR:   Q9KQU6
- GeneID:   2613531
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC1902
- TIGR:   VC_1902
- HOGENOM:   HBG637909
- OMA:   ALYFQHV
- ProtClustDB:   PRK01749
- GO:   GO:0006810
- HAMAP:   MF_00286
- InterPro:   IPR003752
- InterPro:   IPR022920

Pfam domain/function: PF02600 DsbB

EC number: NA

Molecular weight: Translated: 19334; Mature: 19334

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x27bb431c)-; HASH(0x26a4cd08)-; HASH(0x23cc9138)-; HASH(0x40a74d9c)-;

Cys/Met content:

2.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILSSLKTFSQSRLSWLLLLAFVVFFTLCAMYFQHVMLLAPCVMCIYERIAMLGIGVAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIGAIAPQNPVVRWLGFAAWGASSYKGLMLAIEHVNYQFNPSPFATCDLFVTFPAWAPLN
HHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCEECCCCCCHHHHEEECCCCCCHH
QWAPNLFEAYGDCSKVVWQFLTLSMPQWLVVIFAANLLALAIFVVAQLAKTSR
HCCHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MRILSSLKTFSQSRLSWLLLLAFVVFFTLCAMYFQHVMLLAPCVMCIYERIAMLGIGVAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIGAIAPQNPVVRWLGFAAWGASSYKGLMLAIEHVNYQFNPSPFATCDLFVTFPAWAPLN
HHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCEECCCCCCHHHHEEECCCCCCHH
QWAPNLFEAYGDCSKVVWQFLTLSMPQWLVVIFAANLLALAIFVVAQLAKTSR
HCCHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301