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The map label for this gene is sapC [H]

Identifier: 227081833

GI number: 227081833

Start: 1763520

End: 1764407

Strand: Direct

Name: sapC [H]

Synonym: VCM66_1622

Alternate gene names: 227081833

Gene position: 1763520-1764407 (Clockwise)

Preceding gene: 227081832

Following gene: 227081834

Centisome position: 60.97

GC content: 48.99

Gene sequence:

>888_bases
ATGTTAAGCGATAGTATTTATCAAGAAGAACATATTCCAACCCAGTTTGAGCGTTTCTGGCGAAGCTTTCGCGCGAACAA
TCTCGCCATGTTTGGCTTGTGGTCTTTGCTCTTTATTGCATTGGTGACCATTTTGTCGCCTTGGATTGCACCTTACGACC
CGCAAATGCACTCCAGCGTATTGCTCCTGCCCCCTTCTTGGGAGCCCGAAGGTACCGTTGATTATTTCCTTGGCACCGAT
GATCTGGGGCGAGATATCTTGTCTCGCCTGATTGATGGTTCGCTGTTTAGCATAGGTGCTGCCGTCCTGATTACACTGAT
TGCAACCCTAGTCGGTGGAACCATTGGTGCACTGGCTGGCATGACCAAAGGACTGCTTTCTAGTACCTTAAACCATATTC
TCGATACGGTGATGTCTATCCCCTCACTGCTATTGGCGATCATTTTTGTGGCCTTTCTGGGTGCCGGTGAGTTCAACATT
TTACTGGCGATTGGTCTGGCACTGATCCCGCGCTTTATTCGCTCCGTGTATGTTGCGGTACACAATGAAGTGGAAAAAGA
TTATGTCATGGCAGCGCGATTAGACGGAGCGAATGAATTTTATCTGCTCTGGCATTCCATTTTTCCTAATATTCTGCCCA
TTATCGTAGCGGAAATTACCATGGCACTCTCGATTGCGATTCTGGATATCACCGCGCTCGGATTTTTAGGGCTTGGTGCT
CAATCGCCCAGTACAGAGTGGGGAGCGATGCTCGGTGATTCAGTCGAGCTCATCTATATTGCCCCTTGGACAGTGACTCT
CCCCGGCTTAGCCATTATGTTTACGGTGGTAGTGATTAACTTGGTCGGCGATGGTGCACGCCAAGCCCTCAATGCGGGAG
TCGAATAA

Upstream 100 bases:

>100_bases
CAAGCAGGCGTTATCGTTGTCGGTACTCTGGTCTTAACGGCCAATATCCTCTCTGATTTGATTGGCGCAGCAGCTAACCC
CTTGGTAAGGAAAGAGTGGT

Downstream 100 bases:

>100_bases
TGCCGTTACTTGATATTCGTCACTTGACGATTGAGATTGATACTCCACAAGGTCTTGTGAAAGCGGTTGATCGTATGAGC
TTGACCATGAATGAAGGGGA

Product: peptide ABC transporter, permease protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MLSDSIYQEEHIPTQFERFWRSFRANNLAMFGLWSLLFIALVTILSPWIAPYDPQMHSSVLLLPPSWEPEGTVDYFLGTD
DLGRDILSRLIDGSLFSIGAAVLITLIATLVGGTIGALAGMTKGLLSSTLNHILDTVMSIPSLLLAIIFVAFLGAGEFNI
LLAIGLALIPRFIRSVYVAVHNEVEKDYVMAARLDGANEFYLLWHSIFPNILPIIVAEITMALSIAILDITALGFLGLGA
QSPSTEWGAMLGDSVELIYIAPWTVTLPGLAIMFTVVVINLVGDGARQALNAGVE

Sequences:

>Translated_295_residues
MLSDSIYQEEHIPTQFERFWRSFRANNLAMFGLWSLLFIALVTILSPWIAPYDPQMHSSVLLLPPSWEPEGTVDYFLGTD
DLGRDILSRLIDGSLFSIGAAVLITLIATLVGGTIGALAGMTKGLLSSTLNHILDTVMSIPSLLLAIIFVAFLGAGEFNI
LLAIGLALIPRFIRSVYVAVHNEVEKDYVMAARLDGANEFYLLWHSIFPNILPIIVAEITMALSIAILDITALGFLGLGA
QSPSTEWGAMLGDSVELIYIAPWTVTLPGLAIMFTVVVINLVGDGARQALNAGVE
>Mature_295_residues
MLSDSIYQEEHIPTQFERFWRSFRANNLAMFGLWSLLFIALVTILSPWIAPYDPQMHSSVLLLPPSWEPEGTVDYFLGTD
DLGRDILSRLIDGSLFSIGAAVLITLIATLVGGTIGALAGMTKGLLSSTLNHILDTVMSIPSLLLAIIFVAFLGAGEFNI
LLAIGLALIPRFIRSVYVAVHNEVEKDYVMAARLDGANEFYLLWHSIFPNILPIIVAEITMALSIAILDITALGFLGLGA
QSPSTEWGAMLGDSVELIYIAPWTVTLPGLAIMFTVVVINLVGDGARQALNAGVE

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=296, Percent_Identity=55.0675675675676, Blast_Score=317, Evalue=6e-88,
Organism=Escherichia coli, GI1789964, Length=283, Percent_Identity=39.9293286219081, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI1787054, Length=288, Percent_Identity=34.375, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1787760, Length=258, Percent_Identity=37.5968992248062, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1789889, Length=251, Percent_Identity=32.6693227091633, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787498, Length=294, Percent_Identity=29.5918367346939, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31975; Mature: 31975

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSDSIYQEEHIPTQFERFWRSFRANNLAMFGLWSLLFIALVTILSPWIAPYDPQMHSSV
CCCCHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
LLLPPSWEPEGTVDYFLGTDDLGRDILSRLIDGSLFSIGAAVLITLIATLVGGTIGALAG
EEECCCCCCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTKGLLSSTLNHILDTVMSIPSLLLAIIFVAFLGAGEFNILLAIGLALIPRFIRSVYVAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
HNEVEKDYVMAARLDGANEFYLLWHSIFPNILPIIVAEITMALSIAILDITALGFLGLGA
HHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QSPSTEWGAMLGDSVELIYIAPWTVTLPGLAIMFTVVVINLVGDGARQALNAGVE
CCCCCHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCC
>Mature Secondary Structure
MLSDSIYQEEHIPTQFERFWRSFRANNLAMFGLWSLLFIALVTILSPWIAPYDPQMHSSV
CCCCHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
LLLPPSWEPEGTVDYFLGTDDLGRDILSRLIDGSLFSIGAAVLITLIATLVGGTIGALAG
EEECCCCCCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTKGLLSSTLNHILDTVMSIPSLLLAIIFVAFLGAGEFNILLAIGLALIPRFIRSVYVAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
HNEVEKDYVMAARLDGANEFYLLWHSIFPNILPIIVAEITMALSIAILDITALGFLGLGA
HHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QSPSTEWGAMLGDSVELIYIAPWTVTLPGLAIMFTVVVINLVGDGARQALNAGVE
CCCCCHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]