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The map label for this gene is sapB [H]

Identifier: 227081832

GI number: 227081832

Start: 1762571

End: 1763533

Strand: Direct

Name: sapB [H]

Synonym: VCM66_1621

Alternate gene names: 227081832

Gene position: 1762571-1763533 (Clockwise)

Preceding gene: 227081831

Following gene: 227081833

Centisome position: 60.94

GC content: 47.98

Gene sequence:

>963_bases
ATGTTCGTCTATACGGTCCGTAAATTTAACTTATTTATCATCACCTTGCTTATCTTGACCATGGTCGGCTACAGCTTAGC
CAGATTTGACCCGCACTCGCCTTGGACGCTGATCGGCTTTTGGCAAGGATGGTCAAGCTATTTGGTGCAACTGATGGAAT
TCAACTTTGGCCTCAATAAAAATGGGGTACCGATTCTCCATGAGTTACTGGTGGTATTTCCGGCCACCATTGAGCTGTGT
ACCATCGCGTTTATCCTCTCTTTGCTCGTAGGAATTCCTATCGGAACACTGGCGGGAATGCGACAAGGGAAATGGTTAGA
CACTATTATCTCGTTCATTTCGATGTCGGGATATTCTGCCCCTATTTTCTGGCTGGCGCTGATGATGATCATGGCGTTTT
CACTGCATTTCCCGGTATTTCCTGTGGCGGGACGCTATGACTTGCTGTATCAAATTGATCACGTTACCGGCTTTGCCCTG
ATTGATGCCTTTTTGTCTCAATCCCCCTACCGCAGCCAAGCGCTGCAAAGTGTGATAGAGCATTTAACGCTGCCCTGCTT
AGTGCTGGCGCTGGCGCCGACCACGCAAGTCATCGGCCAAATGCGCGCTTCGGTTGCCGAAGTCATGAACCAAAACTATA
TCCGTGCCGCCAAAATTAAAGGCTTGTCTAACTATCAAATCGTCACTCAGCACGTTTTACGCAATGCGATTCCGCCGATG
ATCCCGAAATTTGGCGTTCAACTTTCCAGCATGCTGACCTTAGCCATTATTACTGAATCGATCTTTAACTGGCCGGGTAT
CGGCCGTTGGTTATTGGATGCATTAGCCAACCGTGATTTTATGTCGATTCAAGCAGGCGTTATCGTTGTCGGTACTCTGG
TCTTAACGGCCAATATCCTCTCTGATTTGATTGGCGCAGCAGCTAACCCCTTGGTAAGGAAAGAGTGGTATGTTAAGCGA
TAG

Upstream 100 bases:

>100_bases
ACGGCATACAGTTTACCGCTTATAGCAAATCATTAACGGGCATTCGCATTAGTCCATTTAATGTCCAACCGTTTAATACT
GTCGAGAGGGTGGCCGAGTA

Downstream 100 bases:

>100_bases
TATTTATCAAGAAGAACATATTCCAACCCAGTTTGAGCGTTTCTGGCGAAGCTTTCGCGCGAACAATCTCGCCATGTTTG
GCTTGTGGTCTTTGCTCTTT

Product: peptide ABC transporter, permease protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MFVYTVRKFNLFIITLLILTMVGYSLARFDPHSPWTLIGFWQGWSSYLVQLMEFNFGLNKNGVPILHELLVVFPATIELC
TIAFILSLLVGIPIGTLAGMRQGKWLDTIISFISMSGYSAPIFWLALMMIMAFSLHFPVFPVAGRYDLLYQIDHVTGFAL
IDAFLSQSPYRSQALQSVIEHLTLPCLVLALAPTTQVIGQMRASVAEVMNQNYIRAAKIKGLSNYQIVTQHVLRNAIPPM
IPKFGVQLSSMLTLAIITESIFNWPGIGRWLLDALANRDFMSIQAGVIVVGTLVLTANILSDLIGAAANPLVRKEWYVKR

Sequences:

>Translated_320_residues
MFVYTVRKFNLFIITLLILTMVGYSLARFDPHSPWTLIGFWQGWSSYLVQLMEFNFGLNKNGVPILHELLVVFPATIELC
TIAFILSLLVGIPIGTLAGMRQGKWLDTIISFISMSGYSAPIFWLALMMIMAFSLHFPVFPVAGRYDLLYQIDHVTGFAL
IDAFLSQSPYRSQALQSVIEHLTLPCLVLALAPTTQVIGQMRASVAEVMNQNYIRAAKIKGLSNYQIVTQHVLRNAIPPM
IPKFGVQLSSMLTLAIITESIFNWPGIGRWLLDALANRDFMSIQAGVIVVGTLVLTANILSDLIGAAANPLVRKEWYVKR
>Mature_320_residues
MFVYTVRKFNLFIITLLILTMVGYSLARFDPHSPWTLIGFWQGWSSYLVQLMEFNFGLNKNGVPILHELLVVFPATIELC
TIAFILSLLVGIPIGTLAGMRQGKWLDTIISFISMSGYSAPIFWLALMMIMAFSLHFPVFPVAGRYDLLYQIDHVTGFAL
IDAFLSQSPYRSQALQSVIEHLTLPCLVLALAPTTQVIGQMRASVAEVMNQNYIRAAKIKGLSNYQIVTQHVLRNAIPPM
IPKFGVQLSSMLTLAIITESIFNWPGIGRWLLDALANRDFMSIQAGVIVVGTLVLTANILSDLIGAAANPLVRKEWYVKR

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4168

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787550, Length=321, Percent_Identity=49.5327102803738, Blast_Score=329, Evalue=2e-91,
Organism=Escherichia coli, GI1789965, Length=341, Percent_Identity=32.8445747800587, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1787761, Length=246, Percent_Identity=36.5853658536585, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789888, Length=340, Percent_Identity=27.3529411764706, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1787053, Length=277, Percent_Identity=28.158844765343, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787497, Length=334, Percent_Identity=25.1497005988024, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788504, Length=246, Percent_Identity=26.4227642276423, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35727; Mature: 35727

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVYTVRKFNLFIITLLILTMVGYSLARFDPHSPWTLIGFWQGWSSYLVQLMEFNFGLNK
CEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCC
NGVPILHELLVVFPATIELCTIAFILSLLVGIPIGTLAGMRQGKWLDTIISFISMSGYSA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHCCCCCC
PIFWLALMMIMAFSLHFPVFPVAGRYDLLYQIDHVTGFALIDAFLSQSPYRSQALQSVIE
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
HLTLPCLVLALAPTTQVIGQMRASVAEVMNQNYIRAAKIKGLSNYQIVTQHVLRNAIPPM
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCC
IPKFGVQLSSMLTLAIITESIFNWPGIGRWLLDALANRDFMSIQAGVIVVGTLVLTANIL
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
SDLIGAAANPLVRKEWYVKR
HHHHHHHCCCHHHHHHCCCC
>Mature Secondary Structure
MFVYTVRKFNLFIITLLILTMVGYSLARFDPHSPWTLIGFWQGWSSYLVQLMEFNFGLNK
CEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCC
NGVPILHELLVVFPATIELCTIAFILSLLVGIPIGTLAGMRQGKWLDTIISFISMSGYSA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHCCCCCC
PIFWLALMMIMAFSLHFPVFPVAGRYDLLYQIDHVTGFALIDAFLSQSPYRSQALQSVIE
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
HLTLPCLVLALAPTTQVIGQMRASVAEVMNQNYIRAAKIKGLSNYQIVTQHVLRNAIPPM
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCC
IPKFGVQLSSMLTLAIITESIFNWPGIGRWLLDALANRDFMSIQAGVIVVGTLVLTANIL
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
SDLIGAAANPLVRKEWYVKR
HHHHHHHCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]