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The map label for this gene is sapD [H]

Identifier: 227081834

GI number: 227081834

Start: 1764407

End: 1765402

Strand: Direct

Name: sapD [H]

Synonym: VCM66_1623

Alternate gene names: 227081834

Gene position: 1764407-1765402 (Clockwise)

Preceding gene: 227081833

Following gene: 227081835

Centisome position: 61.0

GC content: 50.0

Gene sequence:

>996_bases
ATGCCGTTACTTGATATTCGTCACTTGACGATTGAGATTGATACTCCACAAGGTCTTGTGAAAGCGGTTGATCGTATGAG
CTTGACCATGAATGAAGGGGAAATTCGTGGCTTAGTGGGTGAATCAGGCTCAGGTAAGAGCTTGGTTGCGAAAGCGATTG
TTGGTATCTGTAAAGAAAACTGGCGCGTCACGGCTGACCGTATGCGTCTTGGCAATATTGATTTGTTGCAGCTCACCCCG
CGTGAACGCCGACGCGTGATCGCACGCGATGTGGCAATGATTTTCCAAGAGCCTTCCACCTGTCTTGATCCATCTGAAGA
GGTTGGACGACAACTGATTGAGTCCATCCCATTTCGCACCTTCGAAGGACGCTGGTGGGAGCGTTTCACATGGCGGAAAA
AGCAGGCGATTGCTTTGCTGCACAAAGTCGGCATCAAAGATCACAAAGACATCATGTCTAGCTACCCTTATGAGCTGACG
GATGGCGAGTGTCAGAAAGTGATGATTGCGATGGCCATTGCCGCTAAACCGAAATTGCTGATCGCAGATGAACCCACCAA
CGACGTGGATCCCATCACTCAATCGCAAATTTTGCGTTTGCTGAGTCGCATGAATCAGGTCAATAACACCTCGATCCTGC
TCATCGGCCATGACTTAACCACCATTACTCAGTGGGCGGATCGCATTACGGTTATGTATTGCGGGCAATCGGTGGAATCG
GCGGAAACTGCAAAAATTGTGGCAGAGCCAAAGCACCCCTACACCGCAGCGCTGCTGAAAGCCATGCCAGATTTTAGTGA
CTGGATCCCGCACAAACAGAAATTACAATCTCTCCCCGGCTCAATTCCGCCACTGCAACACTTACCGATTGGCTGCCGCT
TAGGGCCACGTTGCCCTTACGCTCAGCGTCAGTGTGTTGAAGTCCCTCATTCACGCTGGGTAAAAAACCATAAATTTTCT
TGCCATTTCCCGCTCAATATGGAGTCGCCACAATGA

Upstream 100 bases:

>100_bases
GGACAGTGACTCTCCCCGGCTTAGCCATTATGTTTACGGTGGTAGTGATTAACTTGGTCGGCGATGGTGCACGCCAAGCC
CTCAATGCGGGAGTCGAATA

Downstream 100 bases:

>100_bases
GTGCGCTGTTAGAAGTCACCAATCTGCACAAAGACTTTGTCACTCGCTCAGGCTTTTTACGCAAACAGATCCAACATGCG
GTAAAGCCAGTCAGCTTTAC

Product: peptide ABC transporter, ATP-binding protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MPLLDIRHLTIEIDTPQGLVKAVDRMSLTMNEGEIRGLVGESGSGKSLVAKAIVGICKENWRVTADRMRLGNIDLLQLTP
RERRRVIARDVAMIFQEPSTCLDPSEEVGRQLIESIPFRTFEGRWWERFTWRKKQAIALLHKVGIKDHKDIMSSYPYELT
DGECQKVMIAMAIAAKPKLLIADEPTNDVDPITQSQILRLLSRMNQVNNTSILLIGHDLTTITQWADRITVMYCGQSVES
AETAKIVAEPKHPYTAALLKAMPDFSDWIPHKQKLQSLPGSIPPLQHLPIGCRLGPRCPYAQRQCVEVPHSRWVKNHKFS
CHFPLNMESPQ

Sequences:

>Translated_331_residues
MPLLDIRHLTIEIDTPQGLVKAVDRMSLTMNEGEIRGLVGESGSGKSLVAKAIVGICKENWRVTADRMRLGNIDLLQLTP
RERRRVIARDVAMIFQEPSTCLDPSEEVGRQLIESIPFRTFEGRWWERFTWRKKQAIALLHKVGIKDHKDIMSSYPYELT
DGECQKVMIAMAIAAKPKLLIADEPTNDVDPITQSQILRLLSRMNQVNNTSILLIGHDLTTITQWADRITVMYCGQSVES
AETAKIVAEPKHPYTAALLKAMPDFSDWIPHKQKLQSLPGSIPPLQHLPIGCRLGPRCPYAQRQCVEVPHSRWVKNHKFS
CHFPLNMESPQ
>Mature_330_residues
PLLDIRHLTIEIDTPQGLVKAVDRMSLTMNEGEIRGLVGESGSGKSLVAKAIVGICKENWRVTADRMRLGNIDLLQLTPR
ERRRVIARDVAMIFQEPSTCLDPSEEVGRQLIESIPFRTFEGRWWERFTWRKKQAIALLHKVGIKDHKDIMSSYPYELTD
GECQKVMIAMAIAAKPKLLIADEPTNDVDPITQSQILRLLSRMNQVNNTSILLIGHDLTTITQWADRITVMYCGQSVESA
ETAKIVAEPKHPYTAALLKAMPDFSDWIPHKQKLQSLPGSIPPLQHLPIGCRLGPRCPYAQRQCVEVPHSRWVKNHKFSC
HFPLNMESPQ

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4170

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9665248, Length=238, Percent_Identity=28.1512605042017, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787548, Length=328, Percent_Identity=66.1585365853659, Blast_Score=482, Evalue=1e-137,
Organism=Escherichia coli, GI1789963, Length=328, Percent_Identity=42.0731707317073, Blast_Score=264, Evalue=6e-72,
Organism=Escherichia coli, GI1787759, Length=328, Percent_Identity=38.719512195122, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI48994883, Length=307, Percent_Identity=36.4820846905537, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1787500, Length=307, Percent_Identity=34.8534201954397, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI145693107, Length=270, Percent_Identity=36.6666666666667, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1788506, Length=269, Percent_Identity=36.4312267657993, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789962, Length=319, Percent_Identity=29.7805642633229, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1787758, Length=292, Percent_Identity=30.1369863013699, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789890, Length=263, Percent_Identity=30.7984790874525, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787547, Length=268, Percent_Identity=29.4776119402985, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789891, Length=253, Percent_Identity=30.4347826086957, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786398, Length=261, Percent_Identity=28.3524904214559, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994997, Length=263, Percent_Identity=29.277566539924, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789032, Length=266, Percent_Identity=27.4436090225564, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI87081791, Length=290, Percent_Identity=27.9310344827586, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1789873, Length=217, Percent_Identity=30.4147465437788, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788450, Length=240, Percent_Identity=27.0833333333333, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1788225, Length=238, Percent_Identity=28.1512605042017, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786703, Length=240, Percent_Identity=27.9166666666667, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787089, Length=243, Percent_Identity=28.3950617283951, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787029, Length=234, Percent_Identity=26.0683760683761, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789672, Length=245, Percent_Identity=28.1632653061224, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790162, Length=241, Percent_Identity=23.6514522821577, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87081834, Length=211, Percent_Identity=27.9620853080569, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787370, Length=247, Percent_Identity=26.7206477732794, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI48995001, Length=238, Percent_Identity=28.9915966386555, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790544, Length=233, Percent_Identity=26.6094420600858, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787792, Length=242, Percent_Identity=29.3388429752066, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786345, Length=229, Percent_Identity=29.2576419213974, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790467, Length=237, Percent_Identity=24.8945147679325, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082267, Length=244, Percent_Identity=23.3606557377049, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081709, Length=237, Percent_Identity=22.3628691983122, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788644, Length=129, Percent_Identity=26.3565891472868, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786872, Length=215, Percent_Identity=26.046511627907, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1786253, Length=214, Percent_Identity=25.7009345794392, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 37528; Mature: 37397

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDIRHLTIEIDTPQGLVKAVDRMSLTMNEGEIRGLVGESGSGKSLVAKAIVGICKEN
CCCEEEEEEEEEEECCHHHHHHHHHHHEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCC
WRVTADRMRLGNIDLLQLTPRERRRVIARDVAMIFQEPSTCLDPSEEVGRQLIESIPFRT
CEEEHHHEEECCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCC
FEGRWWERFTWRKKQAIALLHKVGIKDHKDIMSSYPYELTDGECQKVMIAMAIAAKPKLL
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEE
IADEPTNDVDPITQSQILRLLSRMNQVNNTSILLIGHDLTTITQWADRITVMYCGQSVES
EECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHEEEEEECCCCCC
AETAKIVAEPKHPYTAALLKAMPDFSDWIPHKQKLQSLPGSIPPLQHLPIGCRLGPRCPY
CHHHEEEECCCCCHHHHHHHHCCCHHHHCCCHHHHHHCCCCCCCHHCCCCCCCCCCCCCH
AQRQCVEVPHSRWVKNHKFSCHFPLNMESPQ
HHHHHHHCCHHHHHHCCCEEEEECCCCCCCC
>Mature Secondary Structure 
PLLDIRHLTIEIDTPQGLVKAVDRMSLTMNEGEIRGLVGESGSGKSLVAKAIVGICKEN
CCEEEEEEEEEEECCHHHHHHHHHHHEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCC
WRVTADRMRLGNIDLLQLTPRERRRVIARDVAMIFQEPSTCLDPSEEVGRQLIESIPFRT
CEEEHHHEEECCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCC
FEGRWWERFTWRKKQAIALLHKVGIKDHKDIMSSYPYELTDGECQKVMIAMAIAAKPKLL
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEE
IADEPTNDVDPITQSQILRLLSRMNQVNNTSILLIGHDLTTITQWADRITVMYCGQSVES
EECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHEEEEEECCCCCC
AETAKIVAEPKHPYTAALLKAMPDFSDWIPHKQKLQSLPGSIPPLQHLPIGCRLGPRCPY
CHHHEEEECCCCCHHHHHHHHCCCHHHHCCCHHHHHHCCCCCCCHHCCCCCCCCCCCCCH
AQRQCVEVPHSRWVKNHKFSCHFPLNMESPQ
HHHHHHHCCHHHHHHCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]