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The map label for this gene is 227081516

Identifier: 227081516

GI number: 227081516

Start: 1390005

End: 1391141

Strand: Direct

Name: 227081516

Synonym: VCM66_1300

Alternate gene names: NA

Gene position: 1390005-1391141 (Clockwise)

Preceding gene: 227081515

Following gene: 227081517

Centisome position: 48.06

GC content: 52.07

Gene sequence:

>1137_bases
ATGCATAAATGGATCACTTTTCCGCATCGTGAAGGCACTTGTTCAAGGCAGGCGCATGCGGATTTCCCAGAGCAGGCGAT
TTACGAACGTGAAGCGGGGCGCAGTGGCTTTTTTGGCCCCGCAGCGCATTTTCATCATCAACATGCACCGACAGGTTGGA
GCGAGTGGGAAGGCGAACTGCGTCCACGCGCCTTCAACTTCAATCATGTGGAGGGAGTGAATGCTTTGTCTCCTTGGCAA
GTGCCCCTGTTACTGCACAACCATGAAGTGAAAGTGCGGGTGTGGAAGCTAGAGCAAGCTATGCCAGCGTTGGCGCGCAA
TGCCGATGGTGATGAGCTGCTGTTTATCCATCAAGGTAAAGCGGATCTCTATTGTGACTATGGCCATATGGTCGTCAGTG
AGGGCGACTATGCGCTGATCCCGCGCTCGACCAACTGGCGTCTAGAGCCGATTGAGCCCTTGTTTATTTTGATGATTGAA
AACACCGATGCCGCTTATGCGTTACCCGAAAAAGGCTTAGTCGGCAATCACGCGGTGTTTGATCCTGCCGTGTTGGACGT
GCCTTCGATCAATGATCAATTCCGCGCGCAATACTCTGAGCAGCAGACGCAAGTGCAGGTAAAACGTCATGGGCAGCTAA
GCACCATCACCTTCCCGTTTAATCCTTTGGATGCGGTGGGTTGGCATGGCGATCTCTCTGTTGTGCGCCTCAACTGGCGT
GATATTCGCCCGCTGATGTCGCATCGCTACCATCTTCCGCCTTCGGCACATACCACCTTTGTCGGCCAAGGTTTTGTGGT
GTGTACTTTTGTCCCTCGTCCCATTGAAAGTGATCCCGGCGCGCTGAAAGTGCCGTTTTATCACAACAATGATGATTATG
ATGAAGTGCTGTTTTACCACGCTGGCGATTTTTTCAGCCGTGACAATATTGAAGCGGGCATGGTGACCTTCCACCCAGCC
GGTTTTACTCACGGGCCGCATCCGAAAGCGTTCCAAGCCGGCTTGGAATATCGCAAAAAATTCACTGATGAAGTGGCAGT
AATGATTGATACCCGCCATGCGCTACAGTTTAGTGACGCAGCGCAGCAGGTGGAAAATCGTCAGTATGTTTACAGTTGGC
AGAGCAAAGTGGAGTAG

Upstream 100 bases:

>100_bases
ATCATTCAGCGCAAAGGTAATCAAGGATTTGGTGAAGGTAACTTCAAAGCGCTGTTTGAATCGATTGAAGAAGATCAGAT
CCGCCGTGGAGTATTGACTG

Downstream 100 bases:

>100_bases
GGCGATATGAAATTAGCGACTCTGAAAAATGGAATGCGTGATGGTCAACTGGTGGTGGTGAGCCGAGATTTAACCCTGTG
TGTTGCAGTACCTGACATTG

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MHKWITFPHREGTCSRQAHADFPEQAIYEREAGRSGFFGPAAHFHHQHAPTGWSEWEGELRPRAFNFNHVEGVNALSPWQ
VPLLLHNHEVKVRVWKLEQAMPALARNADGDELLFIHQGKADLYCDYGHMVVSEGDYALIPRSTNWRLEPIEPLFILMIE
NTDAAYALPEKGLVGNHAVFDPAVLDVPSINDQFRAQYSEQQTQVQVKRHGQLSTITFPFNPLDAVGWHGDLSVVRLNWR
DIRPLMSHRYHLPPSAHTTFVGQGFVVCTFVPRPIESDPGALKVPFYHNNDDYDEVLFYHAGDFFSRDNIEAGMVTFHPA
GFTHGPHPKAFQAGLEYRKKFTDEVAVMIDTRHALQFSDAAQQVENRQYVYSWQSKVE

Sequences:

>Translated_378_residues
MHKWITFPHREGTCSRQAHADFPEQAIYEREAGRSGFFGPAAHFHHQHAPTGWSEWEGELRPRAFNFNHVEGVNALSPWQ
VPLLLHNHEVKVRVWKLEQAMPALARNADGDELLFIHQGKADLYCDYGHMVVSEGDYALIPRSTNWRLEPIEPLFILMIE
NTDAAYALPEKGLVGNHAVFDPAVLDVPSINDQFRAQYSEQQTQVQVKRHGQLSTITFPFNPLDAVGWHGDLSVVRLNWR
DIRPLMSHRYHLPPSAHTTFVGQGFVVCTFVPRPIESDPGALKVPFYHNNDDYDEVLFYHAGDFFSRDNIEAGMVTFHPA
GFTHGPHPKAFQAGLEYRKKFTDEVAVMIDTRHALQFSDAAQQVENRQYVYSWQSKVE
>Mature_378_residues
MHKWITFPHREGTCSRQAHADFPEQAIYEREAGRSGFFGPAAHFHHQHAPTGWSEWEGELRPRAFNFNHVEGVNALSPWQ
VPLLLHNHEVKVRVWKLEQAMPALARNADGDELLFIHQGKADLYCDYGHMVVSEGDYALIPRSTNWRLEPIEPLFILMIE
NTDAAYALPEKGLVGNHAVFDPAVLDVPSINDQFRAQYSEQQTQVQVKRHGQLSTITFPFNPLDAVGWHGDLSVVRLNWR
DIRPLMSHRYHLPPSAHTTFVGQGFVVCTFVPRPIESDPGALKVPFYHNNDDYDEVLFYHAGDFFSRDNIEAGMVTFHPA
GFTHGPHPKAFQAGLEYRKKFTDEVAVMIDTRHALQFSDAAQQVENRQYVYSWQSKVE

Specific function: Unknown

COG id: COG3508

COG function: function code Q; Homogentisate 1,2-dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the homogentisate dioxygenase family

Homologues:

Organism=Drosophila melanogaster, GI24583650, Length=280, Percent_Identity=23.9285714285714, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1345_VIBCH (Q9KSB4)

Other databases:

- EMBL:   AE003852
- PIR:   D82211
- RefSeq:   NP_230989.1
- ProteinModelPortal:   Q9KSB4
- GeneID:   2614799
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC1345
- TIGR:   VC_1345
- HOGENOM:   HBG564210
- OMA:   PYCERDL
- ProtClustDB:   CLSK874326
- InterPro:   IPR011051
- InterPro:   IPR005708
- InterPro:   IPR014710
- Gene3D:   G3DSA:2.60.120.10
- PANTHER:   PTHR11056

Pfam domain/function: PF04209 HgmA; SSF51182 RmlC_like_cupin

EC number: NA

Molecular weight: Translated: 43247; Mature: 43247

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKWITFPHREGTCSRQAHADFPEQAIYEREAGRSGFFGPAAHFHHQHAPTGWSEWEGEL
CCCCEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHHCCCCC
RPRAFNFNHVEGVNALSPWQVPLLLHNHEVKVRVWKLEQAMPALARNADGDELLFIHQGK
CCEEECCCCCCCCCCCCCCEEEEEEECCEEEEEEEEEHHHHHHHHCCCCCCEEEEEECCC
ADLYCDYGHMVVSEGDYALIPRSTNWRLEPIEPLFILMIENTDAAYALPEKGLVGNHAVF
CCEEEECCEEEEECCCEEEEECCCCCEECCCCEEEEEEEECCCCEEECCCCCCCCCCCCC
DPAVLDVPSINDQFRAQYSEQQTQVQVKRHGQLSTITFPFNPLDAVGWHGDLSVVRLNWR
CCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEEECHH
DIRPLMSHRYHLPPSAHTTFVGQGFVVCTFVPRPIESDPGALKVPFYHNNDDYDEVLFYH
HHHHHHHCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCCEEEEEEECCCCCHHHEEEEE
AGDFFSRDNIEAGMVTFHPAGFTHGPHPKAFQAGLEYRKKFTDEVAVMIDTRHALQFSDA
CCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHH
AQQVENRQYVYSWQSKVE
HHHHHCCEEEEEECCCCC
>Mature Secondary Structure
MHKWITFPHREGTCSRQAHADFPEQAIYEREAGRSGFFGPAAHFHHQHAPTGWSEWEGEL
CCCCEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHHCCCCC
RPRAFNFNHVEGVNALSPWQVPLLLHNHEVKVRVWKLEQAMPALARNADGDELLFIHQGK
CCEEECCCCCCCCCCCCCCEEEEEEECCEEEEEEEEEHHHHHHHHCCCCCCEEEEEECCC
ADLYCDYGHMVVSEGDYALIPRSTNWRLEPIEPLFILMIENTDAAYALPEKGLVGNHAVF
CCEEEECCEEEEECCCEEEEECCCCCEECCCCEEEEEEEECCCCEEECCCCCCCCCCCCC
DPAVLDVPSINDQFRAQYSEQQTQVQVKRHGQLSTITFPFNPLDAVGWHGDLSVVRLNWR
CCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEEECHH
DIRPLMSHRYHLPPSAHTTFVGQGFVVCTFVPRPIESDPGALKVPFYHNNDDYDEVLFYH
HHHHHHHCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCCEEEEEEECCCCCHHHEEEEE
AGDFFSRDNIEAGMVTFHPAGFTHGPHPKAFQAGLEYRKKFTDEVAVMIDTRHALQFSDA
CCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHH
AQQVENRQYVYSWQSKVE
HHHHHCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301