Click here to switch to the map view.

The map label for this gene is nudL [H]

Identifier: 227081473

GI number: 227081473

Start: 1340472

End: 1341086

Strand: Reverse

Name: nudL [H]

Synonym: VCM66_1257

Alternate gene names: 227081473

Gene position: 1341086-1340472 (Counterclockwise)

Preceding gene: 227081474

Following gene: 227081472

Centisome position: 46.36

GC content: 46.18

Gene sequence:

>615_bases
TTGCAAAACATTAGCCGTCACGAGTTTATCCAGCAGTTTCAGCTCCATTTACCCGCCGCCTATCCTCAGGAAAGCTTGCG
GCGCGTCGCACATTTAGCGCCAGAGAAGCTACGTAAAGCGTCGGTATTGATTGGCGTAGTAGAACGCCCGCAAGGCCTAC
AAGTGATCATGACCAAGCGCGCAGCACATTTGAGGCATCATCCCGGGCAAATCAGTTTTCCCGGCGGAAAGTACGAAGAG
AGCGACCACTCGTTACAGCAGACGGCAAAGCGAGAAGCACGAGAAGAGATTGGCATCCCAGAAGAGAAAATTCGTATTGT
TGGTCAGTTGCCTGAGTTAGTGACCGTAAGCCAATTTGCCGTGACGCCTTTTTTAGCTTTTGTCGAATCCGACTACCCGA
TTCAGCTCGATCACAACGAAGTCGATGAAGTGTTTGAAGTGCCGATCAGTTTTTTGCTTGATCGAAAAAAGATCTACAGC
GGGACTTTTCAGTTAAAAAAACACCGTCATAAACTGTTCGCCCTCTCCTATAAACAACATTTTATATGGGGTATGACCGC
ACAAATCATCCAATCCCTTCAAAAACAATTTATTAATTACAATGAGTTAGTTTGA

Upstream 100 bases:

>100_bases
GGGGATATCATATCTGGCAAATGTGCAGTAACCGACAGCGCATCCTTTTGAAACACGCTATAACAGGTGTTATACGTTAA
TCACGGTATAGAGGCCTGCT

Downstream 100 bases:

>100_bases
AGGCCTATTTTTCTCACTTTGGGCAAGGCAATACAAATCATTAGAAAATCTAATCAAAAAAACAAGCAAACGTTTTCCTG
ACCATTCACTGAGAATTTTT

Product: MutT/nudix family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MQNISRHEFIQQFQLHLPAAYPQESLRRVAHLAPEKLRKASVLIGVVERPQGLQVIMTKRAAHLRHHPGQISFPGGKYEE
SDHSLQQTAKREAREEIGIPEEKIRIVGQLPELVTVSQFAVTPFLAFVESDYPIQLDHNEVDEVFEVPISFLLDRKKIYS
GTFQLKKHRHKLFALSYKQHFIWGMTAQIIQSLQKQFINYNELV

Sequences:

>Translated_204_residues
MQNISRHEFIQQFQLHLPAAYPQESLRRVAHLAPEKLRKASVLIGVVERPQGLQVIMTKRAAHLRHHPGQISFPGGKYEE
SDHSLQQTAKREAREEIGIPEEKIRIVGQLPELVTVSQFAVTPFLAFVESDYPIQLDHNEVDEVFEVPISFLLDRKKIYS
GTFQLKKHRHKLFALSYKQHFIWGMTAQIIQSLQKQFINYNELV
>Mature_204_residues
MQNISRHEFIQQFQLHLPAAYPQESLRRVAHLAPEKLRKASVLIGVVERPQGLQVIMTKRAAHLRHHPGQISFPGGKYEE
SDHSLQQTAKREAREEIGIPEEKIRIVGQLPELVTVSQFAVTPFLAFVESDYPIQLDHNEVDEVFEVPISFLLDRKKIYS
GTFQLKKHRHKLFALSYKQHFIWGMTAQIIQSLQKQFINYNELV

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=116, Percent_Identity=33.6206896551724, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1788115, Length=197, Percent_Identity=35.0253807106599, Blast_Score=113, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17536993, Length=136, Percent_Identity=34.5588235294118, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17510677, Length=105, Percent_Identity=34.2857142857143, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI18859683, Length=168, Percent_Identity=30.3571428571429, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 23673; Mature: 23673

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNISRHEFIQQFQLHLPAAYPQESLRRVAHLAPEKLRKASVLIGVVERPQGLQVIMTKR
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHH
AAHLRHHPGQISFPGGKYEESDHSLQQTAKREAREEIGIPEEKIRIVGQLPELVTVSQFA
HHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHH
VTPFLAFVESDYPIQLDHNEVDEVFEVPISFLLDRKKIYSGTFQLKKHRHKLFALSYKQH
HHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIWGMTAQIIQSLQKQFINYNELV
HHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MQNISRHEFIQQFQLHLPAAYPQESLRRVAHLAPEKLRKASVLIGVVERPQGLQVIMTKR
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHH
AAHLRHHPGQISFPGGKYEESDHSLQQTAKREAREEIGIPEEKIRIVGQLPELVTVSQFA
HHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHH
VTPFLAFVESDYPIQLDHNEVDEVFEVPISFLLDRKKIYSGTFQLKKHRHKLFALSYKQH
HHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIWGMTAQIIQSLQKQFINYNELV
HHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA