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The map label for this gene is yidC

Identifier: 227080241

GI number: 227080241

Start: 2271

End: 3896

Strand: Reverse

Name: yidC

Synonym: VCM66_0004

Alternate gene names: 227080241

Gene position: 3896-2271 (Counterclockwise)

Preceding gene: 227080242

Following gene: 227080240

Centisome position: 0.13

GC content: 49.2

Gene sequence:

>1626_bases
ATGGATTCTCAACGTAATATCTTGTTAATCGCTCTGGCGCTGGTTTCTTTCCTACTGTTTCAACAATGGCAAGTAGCGAA
GAACCCTGCACCGCAAGCGACACAGCAGGCCCAATCCACAGGCGCAGCTCCTGCTCCTTCATTTTCCGATGAGTTAGATC
CAACGCCTGCACAAAATGTGGCGGCGAAGGCCAAGACCATTACCGTCTCAACCGATGTACTGACTCTGTCTATTGATACG
CTCGGCGGCGATGTGGTTAGCGCAAAACTGAATCAATACTCAGAAGAGCTCAATTCGCCTGAGTCTTTTGTCTTGTTGCA
AAACACCCAAGGCCATCAGTTTATTGCTCAAAGTGGTTTAGTCGGCCCACAAGGCATTGACGTCACCAGCAATAATCGTC
CCGCTTACCAAGTGAGTGCGGATAGTTTCACTCTGGCCGAAGGCCAAGATGAACTGCGCATTCCTATGACCTATCAAGCC
AATGGCATTGACTACACGAAAACCTTCATTCTTAAGCGTGGTAGCTACGCCGTGGATGTGGTGTTTGACGTCGCCAATAA
TTCAGGTAGCGAAGCCACACTAGGTATGTATGCTCACCTGCGCCAAAATCTGCTGGATTCTGGTGGCAACCTCGCCATGC
CAACTTACCGTGGTGGTGCTTACTCAACCAGCGATGTGCGTTACAAGAAGTACAGCTTCGACGACATGAAAGATCGCAAC
CTCAGTGCACCAAACGATGTGACGGTAAACTGGGTCGCGATGATCCAGCACTACTTCGCTTCAGCATGGATCCCACGTGA
TGAGCCGCAAGCACAGCTTTACTCACGCGTTATCAATAATTTAGGTGATATGGGTATCCGTACACCAAACAAAACCATTG
CCAACGGTGATAAAGCAGAGTTTGAAGCAACCTTATGGGTAGGCCCAAAACTGCAAGACCAAATGGCCGCAACAGCCCCT
AATCTTGATCTGGTGGTTGATTATGGTTGGTTGTGGTTCATTGCTAAGCCACTGCACTGGTTGCTGTCTGTGATTCAGAC
CTTTGTTGGCAACTGGGGTGTGGCCATCATCTGCTTAACCTTTATTGTTCGTGGTGCGATGTACCCACTGACCAAAGCAC
AGTACACCTCAATGGCGAAAATGCGCATGCTGCAACCTAAACTGCAAGCGATGCGTGAGCGGATTGGCGATGATCGCCAG
CGCATGAGCCAAGAGATGATGGAGCTGTATAAGAAAGAGAAAGTAAACCCACTGGGTGGCTGTCTCCCTATCCTTCTGCA
AATGCCGATTTTCATTGCGCTGTACTGGGCACTGATGGAGTCGGTAGAGCTGCGTCACTCTCCATTCTTTGGTTGGATTC
ATGACTTGTCCGCGCAAGATCCTTACTACATCTTGCCACTGCTGATGGGTGCGAGCATGTTCGTTATCCAGAAGATGAGC
CCGACCACGATCACCGATCCAATGCAACAGAAGATCATGACCTTCATGCCAGTCATGTTCACTTTCTTCTTCCTGTGGTT
CCCATCAGGTCTGGTTCTGTACTGGTTGGTGTCGAACATCGTAACGCTAATCCAGCAAACGCTGATCTACAAAGCGCTAG
AGAAAAAAGGCTTACACTCCAAGTAA

Upstream 100 bases:

>100_bases
GTTGGTTATCCACCAAACGTCTATTAAAATGCCACCCTTTGAACGAAGGGGGCTTTGACCCCGTTCCACCAGTCCAAAAA
CAAGACAGAGATAAATAACG

Downstream 100 bases:

>100_bases
GTTTGATTGAGTAATAAAGAGGCGGCCAAAAGGTCGCCTTTTTGTTGGCTGCTGATTACAATGGCGCTAATTCAATCCTG
TTCAGGTAACACTATGACAA

Product: putative inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MDSQRNILLIALALVSFLLFQQWQVAKNPAPQATQQAQSTGAAPAPSFSDELDPTPAQNVAAKAKTITVSTDVLTLSIDT
LGGDVVSAKLNQYSEELNSPESFVLLQNTQGHQFIAQSGLVGPQGIDVTSNNRPAYQVSADSFTLAEGQDELRIPMTYQA
NGIDYTKTFILKRGSYAVDVVFDVANNSGSEATLGMYAHLRQNLLDSGGNLAMPTYRGGAYSTSDVRYKKYSFDDMKDRN
LSAPNDVTVNWVAMIQHYFASAWIPRDEPQAQLYSRVINNLGDMGIRTPNKTIANGDKAEFEATLWVGPKLQDQMAATAP
NLDLVVDYGWLWFIAKPLHWLLSVIQTFVGNWGVAIICLTFIVRGAMYPLTKAQYTSMAKMRMLQPKLQAMRERIGDDRQ
RMSQEMMELYKKEKVNPLGGCLPILLQMPIFIALYWALMESVELRHSPFFGWIHDLSAQDPYYILPLLMGASMFVIQKMS
PTTITDPMQQKIMTFMPVMFTFFFLWFPSGLVLYWLVSNIVTLIQQTLIYKALEKKGLHSK

Sequences:

>Translated_541_residues
MDSQRNILLIALALVSFLLFQQWQVAKNPAPQATQQAQSTGAAPAPSFSDELDPTPAQNVAAKAKTITVSTDVLTLSIDT
LGGDVVSAKLNQYSEELNSPESFVLLQNTQGHQFIAQSGLVGPQGIDVTSNNRPAYQVSADSFTLAEGQDELRIPMTYQA
NGIDYTKTFILKRGSYAVDVVFDVANNSGSEATLGMYAHLRQNLLDSGGNLAMPTYRGGAYSTSDVRYKKYSFDDMKDRN
LSAPNDVTVNWVAMIQHYFASAWIPRDEPQAQLYSRVINNLGDMGIRTPNKTIANGDKAEFEATLWVGPKLQDQMAATAP
NLDLVVDYGWLWFIAKPLHWLLSVIQTFVGNWGVAIICLTFIVRGAMYPLTKAQYTSMAKMRMLQPKLQAMRERIGDDRQ
RMSQEMMELYKKEKVNPLGGCLPILLQMPIFIALYWALMESVELRHSPFFGWIHDLSAQDPYYILPLLMGASMFVIQKMS
PTTITDPMQQKIMTFMPVMFTFFFLWFPSGLVLYWLVSNIVTLIQQTLIYKALEKKGLHSK
>Mature_541_residues
MDSQRNILLIALALVSFLLFQQWQVAKNPAPQATQQAQSTGAAPAPSFSDELDPTPAQNVAAKAKTITVSTDVLTLSIDT
LGGDVVSAKLNQYSEELNSPESFVLLQNTQGHQFIAQSGLVGPQGIDVTSNNRPAYQVSADSFTLAEGQDELRIPMTYQA
NGIDYTKTFILKRGSYAVDVVFDVANNSGSEATLGMYAHLRQNLLDSGGNLAMPTYRGGAYSTSDVRYKKYSFDDMKDRN
LSAPNDVTVNWVAMIQHYFASAWIPRDEPQAQLYSRVINNLGDMGIRTPNKTIANGDKAEFEATLWVGPKLQDQMAATAP
NLDLVVDYGWLWFIAKPLHWLLSVIQTFVGNWGVAIICLTFIVRGAMYPLTKAQYTSMAKMRMLQPKLQAMRERIGDDRQ
RMSQEMMELYKKEKVNPLGGCLPILLQMPIFIALYWALMESVELRHSPFFGWIHDLSAQDPYYILPLLMGASMFVIQKMS
PTTITDPMQQKIMTFMPVMFTFFFLWFPSGLVLYWLVSNIVTLIQQTLIYKALEKKGLHSK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Homo sapiens, GI223718097, Length=194, Percent_Identity=26.8041237113402, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790140, Length=553, Percent_Identity=57.6853526220615, Blast_Score=605, Evalue=1e-174,
Organism=Drosophila melanogaster, GI24662345, Length=216, Percent_Identity=26.3888888888889, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21356443, Length=216, Percent_Identity=26.3888888888889, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_VIBC3 (A5F484)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F484
- SMR:   A5F484
- STRING:   A5F484
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A2514
- eggNOG:   COG0706
- HOGENOM:   HBG507812
- OMA:   NVEKEAF
- ProtClustDB:   PRK01318
- BioCyc:   VCHO345073:VC0395_A2514-MONOMER
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 60622; Mature: 60622

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x22cd2d90)-; HASH(0x245e8de4)-; HASH(0x245e7170)-; HASH(0x245eab20)-; HASH(0x245ea8bc)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSQRNILLIALALVSFLLFQQWQVAKNPAPQATQQAQSTGAAPAPSFSDELDPTPAQNV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
AAKAKTITVSTDVLTLSIDTLGGDVVSAKLNQYSEELNSPESFVLLQNTQGHQFIAQSGL
HHHCEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCC
VGPQGIDVTSNNRPAYQVSADSFTLAEGQDELRIPMTYQANGIDYTKTFILKRGSYAVDV
CCCCCCEECCCCCCCEEECCCCEEECCCCCCEEEEEEEECCCCCHHHHHEEECCCEEEEE
VFDVANNSGSEATLGMYAHLRQNLLDSGGNLAMPTYRGGAYSTSDVRYKKYSFDDMKDRN
EEEECCCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCEEEECCCCCCCCCC
LSAPNDVTVNWVAMIQHYFASAWIPRDEPQAQLYSRVINNLGDMGIRTPNKTIANGDKAE
CCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
FEATLWVGPKLQDQMAATAPNLDLVVDYGWLWFIAKPLHWLLSVIQTFVGNWGVAIICLT
EEEEEEECCCHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FIVRGAMYPLTKAQYTSMAKMRMLQPKLQAMRERIGDDRQRMSQEMMELYKKEKVNPLGG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCH
CLPILLQMPIFIALYWALMESVELRHSPFFGWIHDLSAQDPYYILPLLMGASMFVIQKMS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHCCCEEEHCCCC
PTTITDPMQQKIMTFMPVMFTFFFLWFPSGLVLYWLVSNIVTLIQQTLIYKALEKKGLHS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
K
H
>Mature Secondary Structure
MDSQRNILLIALALVSFLLFQQWQVAKNPAPQATQQAQSTGAAPAPSFSDELDPTPAQNV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
AAKAKTITVSTDVLTLSIDTLGGDVVSAKLNQYSEELNSPESFVLLQNTQGHQFIAQSGL
HHHCEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCC
VGPQGIDVTSNNRPAYQVSADSFTLAEGQDELRIPMTYQANGIDYTKTFILKRGSYAVDV
CCCCCCEECCCCCCCEEECCCCEEECCCCCCEEEEEEEECCCCCHHHHHEEECCCEEEEE
VFDVANNSGSEATLGMYAHLRQNLLDSGGNLAMPTYRGGAYSTSDVRYKKYSFDDMKDRN
EEEECCCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCEEEECCCCCCCCCC
LSAPNDVTVNWVAMIQHYFASAWIPRDEPQAQLYSRVINNLGDMGIRTPNKTIANGDKAE
CCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
FEATLWVGPKLQDQMAATAPNLDLVVDYGWLWFIAKPLHWLLSVIQTFVGNWGVAIICLT
EEEEEEECCCHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FIVRGAMYPLTKAQYTSMAKMRMLQPKLQAMRERIGDDRQRMSQEMMELYKKEKVNPLGG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCH
CLPILLQMPIFIALYWALMESVELRHSPFFGWIHDLSAQDPYYILPLLMGASMFVIQKMS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHCCCEEEHCCCC
PTTITDPMQQKIMTFMPVMFTFFFLWFPSGLVLYWLVSNIVTLIQQTLIYKALEKKGLHS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
K
H

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA