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The map label for this gene is apeB [H]

Identifier: 226950772

GI number: 226950772

Start: 3817423

End: 3818721

Strand: Reverse

Name: apeB [H]

Synonym: CLM_3783

Alternate gene names: 226950772

Gene position: 3818721-3817423 (Counterclockwise)

Preceding gene: 226950775

Following gene: 226950771

Centisome position: 91.9

GC content: 29.87

Gene sequence:

>1299_bases
GTGGATAAAATAAAGATATCTAATGAATTAATAGATTTTATATATGATAGTCCATCTCCATATCATGTGGTGCATAATTT
AAAAAATGTATTAACAAAGAAAGGCTTTACAGAGATTAAAGAAAGTGAAGCTTGGAAGTTGAAAAAAGGTGGCAAATATT
TTACTACTAAAAATCATTCTGCTATAATAGCATTTTTTATAGGGGAGGATGAAATAGAAAATTCAGGTTTTAGAATAGTG
GCCTCTCATACAGATTCACCAACTTTTAAAGTAAAGCCTGCTCCGGAAATTTTTGCAGAGGGTAATTATATTAAACTTAA
TACAGAAGTATATGGAGGACCTATACTAAATACCTGGATGGATAGACCTTTATCTTTAGCAGGGAGAGTAGTTTTAAAAG
GGCAAAATCCATTAAAACCTAAAATAAAACTTATAAATATAAAAAGACCTATACTTATAATTCCTAATTTAGCTATTCAT
ATGAATAGAAATGTAAATAAGGGTGTAGAGTTAAATAAACAAAAAGATATGTTGCCTATAATATCAATGATTAAGGATAA
ATTAGAAAAAGAAAATTATTTGGCTAATATAATATGTAAAGAACTTGATGTTAATATAGACGAAATATTAGATTTTGAAT
TGGTCTTATATGAATTTGAAAAGGGATGCCTAATTGGAGACAAAAATGAATTTATATCTATAGGTAAATTAGATGATTTA
TCTATGGTGCATGCGTCCCTTAAGGCGTTGCTTTCTTCCACCAATAATAAATCTACAAAAGTTATGGTATGTTTTGATAA
TGAAGAGGTAGGAAGTGCAACAAAACAAGGAGCAGATTCACCATTTTTGTCTCAAACATTAGAAAGGATAACCTTATGTT
TAAATAAAAATAAAGAAGAGTACTTTAGAACCCTTTCAAAATCATTTATGATATCTTGTGATTCGGCCCATGCTATACAT
CCTAATGTAGGTGAAAAATCAGATCCTACTAATAAGGTTATTATGAATAATGGTCCGGTTATAAAAATTAGCGCTAGTCA
GAGTTATACTTCAGATGCCTATTCTTCTTCTGTATATGAAGAAATATGCCATAGAGCTAAAGTACCAGTACAGAAATTTG
TAAATAGATCTGACGAAAGAGGGGGATCTACTATAGGTCCTATATCTGGAACTCATATAAACATACCATCAGTAGATATA
GGAACAGCATTACTTGCCATGCATTCTATTAGAGAGTTAGGAGGAGTAGAGGATCAAGTTTATGCTATAAAATCCTTTGT
AGAATTTTTTAACATTTAA

Upstream 100 bases:

>100_bases
TAGTAAAATTTTCTATATTAAAATATTTTATAGCATATAATATATTGATATACTTTGATATAATAAGCTTATAAAATATT
ATGAAAAGTAGGTGTTTTAT

Downstream 100 bases:

>100_bases
ATAAAAAGTATTGATTTATTTCATAATTCATGTTAAACTAGTAAAAATTTAATTAAATGAAAGCTACTTATGGAGAGGTG
CTGTAATTAATAGTATTTAT

Product: putative aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MDKIKISNELIDFIYDSPSPYHVVHNLKNVLTKKGFTEIKESEAWKLKKGGKYFTTKNHSAIIAFFIGEDEIENSGFRIV
ASHTDSPTFKVKPAPEIFAEGNYIKLNTEVYGGPILNTWMDRPLSLAGRVVLKGQNPLKPKIKLINIKRPILIIPNLAIH
MNRNVNKGVELNKQKDMLPIISMIKDKLEKENYLANIICKELDVNIDEILDFELVLYEFEKGCLIGDKNEFISIGKLDDL
SMVHASLKALLSSTNNKSTKVMVCFDNEEVGSATKQGADSPFLSQTLERITLCLNKNKEEYFRTLSKSFMISCDSAHAIH
PNVGEKSDPTNKVIMNNGPVIKISASQSYTSDAYSSSVYEEICHRAKVPVQKFVNRSDERGGSTIGPISGTHINIPSVDI
GTALLAMHSIRELGGVEDQVYAIKSFVEFFNI

Sequences:

>Translated_432_residues
MDKIKISNELIDFIYDSPSPYHVVHNLKNVLTKKGFTEIKESEAWKLKKGGKYFTTKNHSAIIAFFIGEDEIENSGFRIV
ASHTDSPTFKVKPAPEIFAEGNYIKLNTEVYGGPILNTWMDRPLSLAGRVVLKGQNPLKPKIKLINIKRPILIIPNLAIH
MNRNVNKGVELNKQKDMLPIISMIKDKLEKENYLANIICKELDVNIDEILDFELVLYEFEKGCLIGDKNEFISIGKLDDL
SMVHASLKALLSSTNNKSTKVMVCFDNEEVGSATKQGADSPFLSQTLERITLCLNKNKEEYFRTLSKSFMISCDSAHAIH
PNVGEKSDPTNKVIMNNGPVIKISASQSYTSDAYSSSVYEEICHRAKVPVQKFVNRSDERGGSTIGPISGTHINIPSVDI
GTALLAMHSIRELGGVEDQVYAIKSFVEFFNI
>Mature_432_residues
MDKIKISNELIDFIYDSPSPYHVVHNLKNVLTKKGFTEIKESEAWKLKKGGKYFTTKNHSAIIAFFIGEDEIENSGFRIV
ASHTDSPTFKVKPAPEIFAEGNYIKLNTEVYGGPILNTWMDRPLSLAGRVVLKGQNPLKPKIKLINIKRPILIIPNLAIH
MNRNVNKGVELNKQKDMLPIISMIKDKLEKENYLANIICKELDVNIDEILDFELVLYEFEKGCLIGDKNEFISIGKLDDL
SMVHASLKALLSSTNNKSTKVMVCFDNEEVGSATKQGADSPFLSQTLERITLCLNKNKEEYFRTLSKSFMISCDSAHAIH
PNVGEKSDPTNKVIMNNGPVIKISASQSYTSDAYSSSVYEEICHRAKVPVQKFVNRSDERGGSTIGPISGTHINIPSVDI
GTALLAMHSIRELGGVEDQVYAIKSFVEFFNI

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=450, Percent_Identity=36.2222222222222, Blast_Score=306, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI17552916, Length=452, Percent_Identity=33.8495575221239, Blast_Score=262, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6321905, Length=459, Percent_Identity=37.4727668845316, Blast_Score=318, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6322746, Length=454, Percent_Identity=28.1938325991189, Blast_Score=192, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 48291; Mature: 48291

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIKISNELIDFIYDSPSPYHVVHNLKNVLTKKGFTEIKESEAWKLKKGGKYFTTKNHS
CCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCEEECCCCEEEEECCCC
AIIAFFIGEDEIENSGFRIVASHTDSPTFKVKPAPEIFAEGNYIKLNTEVYGGPILNTWM
EEEEEEECCCCCCCCCCEEEEECCCCCEEEECCCHHHHCCCCEEEEECEECCCCHHHHHH
DRPLSLAGRVVLKGQNPLKPKIKLINIKRPILIIPNLAIHMNRNVNKGVELNKQKDMLPI
CCCHHHCCEEEEECCCCCCCCEEEEEECCCEEEECCEEEEECCCCCCCCCCCCCCCHHHH
ISMIKDKLEKENYLANIICKELDVNIDEILDFELVLYEFEKGCLIGDKNEFISIGKLDDL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEEECCCCCEECCCCCEEEECCCCHH
SMVHASLKALLSSTNNKSTKVMVCFDNEEVGSATKQGADSPFLSQTLERITLCLNKNKEE
HHHHHHHHHHHHCCCCCCEEEEEEECCCHHCCHHHCCCCCHHHHHHHHHHHHHHCCCHHH
YFRTLSKSFMISCDSAHAIHPNVGEKSDPTNKVIMNNGPVIKISASQSYTSDAYSSSVYE
HHHHHHHHHEEEECCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHH
EICHRAKVPVQKFVNRSDERGGSTIGPISGTHINIPSVDIGTALLAMHSIRELGGVEDQV
HHHHHCCCCHHHHHCCCCCCCCCEECCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHH
YAIKSFVEFFNI
HHHHHHHHHHCC
>Mature Secondary Structure
MDKIKISNELIDFIYDSPSPYHVVHNLKNVLTKKGFTEIKESEAWKLKKGGKYFTTKNHS
CCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCEEECCCCEEEEECCCC
AIIAFFIGEDEIENSGFRIVASHTDSPTFKVKPAPEIFAEGNYIKLNTEVYGGPILNTWM
EEEEEEECCCCCCCCCCEEEEECCCCCEEEECCCHHHHCCCCEEEEECEECCCCHHHHHH
DRPLSLAGRVVLKGQNPLKPKIKLINIKRPILIIPNLAIHMNRNVNKGVELNKQKDMLPI
CCCHHHCCEEEEECCCCCCCCEEEEEECCCEEEECCEEEEECCCCCCCCCCCCCCCHHHH
ISMIKDKLEKENYLANIICKELDVNIDEILDFELVLYEFEKGCLIGDKNEFISIGKLDDL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEEECCCCCEECCCCCEEEECCCCHH
SMVHASLKALLSSTNNKSTKVMVCFDNEEVGSATKQGADSPFLSQTLERITLCLNKNKEE
HHHHHHHHHHHHCCCCCCEEEEEEECCCHHCCHHHCCCCCHHHHHHHHHHHHHHCCCHHH
YFRTLSKSFMISCDSAHAIHPNVGEKSDPTNKVIMNNGPVIKISASQSYTSDAYSSSVYE
HHHHHHHHHEEEECCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHH
EICHRAKVPVQKFVNRSDERGGSTIGPISGTHINIPSVDIGTALLAMHSIRELGGVEDQV
HHHHHCCCCHHHHHCCCCCCCCCEECCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHH
YAIKSFVEFFNI
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA