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The map label for this gene is helD [H]

Identifier: 226950775

GI number: 226950775

Start: 3821541

End: 3823670

Strand: Reverse

Name: helD [H]

Synonym: CLM_3786

Alternate gene names: 226950775

Gene position: 3823670-3821541 (Counterclockwise)

Preceding gene: 226950776

Following gene: 226950772

Centisome position: 92.02

GC content: 25.87

Gene sequence:

>2130_bases
ATGGATAATAATCAGATAAATAATTCCATGGATAAATATATAGAACTAAGTATGGAAAGAGAATATTTAGATTTTATAAT
AGATAAAGTAAGAAAAGAAACAGGAATATATTTAGATAAAAGAAAAGATATAGTAAAAGATATAGTAGAATATAGGAAAG
AATTTTTAGAAGAAGATAAAAATGATGAAGATAAAGTAGCAGAGTACTTTGATCATGAAAGATACTTAAAAGAAAAGCTT
TATGGTTTTACAGATAAAAAACTAAAAGAGCTCACAATTTTAGAACAGAATCCTTACTTTGGAAAAGTTAATTTTATAGA
TGAAGGGGATGAAGATTCTATCTATATAGGTAGATACGGATTTTTAGAAACAGGTAATTATAAACCTTTTATTGTAGATT
GGAGAGCTCCTATATGCCAAATATTTTATCAGGGGAAATTAGGAAATATAGCATATGAATCACCAGATGGTAAAATAGAG
GTAGATGTAAAATCTAAAAGGCAATATGTTATCCGTAAGGGTATATTAAAAGGTATGTTTGATTCTGCTTTAGATGTAAA
AGATGAAGTTCTTCAAATGATTTTAAGTGAAAATACCAAAGAAAAATTAAAGGATATAGTTATGACTATACAAGAAGAGC
AAGATAACTTAATTAGACAGCCTAAAGACAAAGCTATGATTGTTAATGGAGTTGCAGGTAGTGGTAAGACTACCATCGCT
CTTCATAGAGTAGCATACTTATTATATAATTATAGGAACCAAATACAAGATAAAGTACTAATACTAGGACCTAATAATAT
TTTCGTGGATTATATATCAGAAGTGTTACCGAGTCTAGGTGAAAATGGAGTTAAACAAACTACCTTTAAGGATTTTATAG
AAGACTTGCTACCTACAAATAATTTCCTAGAATATGATAACTATATAGAAAGATTTATAAAAAAAGATAATGAATTTATA
GAAGATATAGCATATAAACAATCTAAAGCATATATGGAAGATTTAGATAGCTTTATGGAAGATCTAGAACGAAACATATT
TATTACAGAAGATGTAATATTAATGGAAGAAGTTGCTATAGATAAAAAAGAAATAGACGAAATGCTTCATTCCTATTATA
AATATATGCCTTTATTTAAAAGAAGTAGGAAGATAAAAAGAATAGTATTTTCTAAAATAAGAGATGTGAGAAACAAAAAA
GTTTATGAAACTCAAAGACAATATGAAGAAAAACTAAAAAAATTATCAGAGGAAGAACTACAACTAAATAAAAATAATTT
AGAGTTTGAAAGAAAAAATAATATAAGAAACATAGTGAGAAAATCTATGGAGTTAAAGAAATCATTAGTATGGTTAGATA
ATCCACAGGTTTTGGATATATATAATGAGTTTAATAATAACAATAAGCTTACTGTAGATGATATTATAGCTATATTATAT
TTAAAAATAAAATTAGAGGGTTTAAGATATAGGAATGAAATAAAACATATAGTAATAGACGAAGCACAGGATTATTCATT
TTTACAGTTTGTAGTATTAAAAGAACTTACAGATTGTCAATCTATAACTATAGTAGGAGATGTTAATCAAAGAACATTAC
CTTGCAAGGATGAAGTTCCTATGTTATGCTTAGATTCTGTCTTTAATAGAGTCGATGTAGAGTATTTTAATTTAGATAAA
AGTTATAGATCAACAAAAGAGATTATAGAGTACGCTAATAAACATTTAAAAACAAATAAAATTGTTCCTTTGGTGAGAGA
AGGAGACCCTGTAAAAGAAGTAACAGTGAAGAATTCAAGGGAAGCAATAGATAAGGTTAATTATTATTTAAGTTACTTAG
AAAATAAAGGGTATGAAAATATTGCAATTATAACAACTACACTAGAACAGGGGAAAGTTATAGGATCAGAATTAAAAAAG
CAAATGTATATTAATTTAATAGAAAGAGAAGATATAATTTATTCTGGAGGTAAGATAATAATTCCATCTTATTTATCAAA
AGGTTTAGAATTTGATGCTACTATTTTAATATTAGATGATAATAATATAGGAGAAAATTTAAAATATATAATGGCTACAA
GAGCTTTACATGAAATGATAGTTGTACACAAAGAAGGTAAAAAGTTATAA

Upstream 100 bases:

>100_bases
AAATATTAGATAAAAAGGCTGTAGATGAACTTGTAATGGATACAAAGGAAACAAGTGATAAATCACCTATAGAAGAATAA
ACCGGAATGGAGAGAGGTTT

Downstream 100 bases:

>100_bases
ACAGTGTGGATAACTTTTTACTAATAATGGGGACTATTTGTACAAAAATATTACACCATAAGTTGTAATTAATGATATTT
AAATAAAATTAATAAAAAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 709; Mature: 709

Protein sequence:

>709_residues
MDNNQINNSMDKYIELSMEREYLDFIIDKVRKETGIYLDKRKDIVKDIVEYRKEFLEEDKNDEDKVAEYFDHERYLKEKL
YGFTDKKLKELTILEQNPYFGKVNFIDEGDEDSIYIGRYGFLETGNYKPFIVDWRAPICQIFYQGKLGNIAYESPDGKIE
VDVKSKRQYVIRKGILKGMFDSALDVKDEVLQMILSENTKEKLKDIVMTIQEEQDNLIRQPKDKAMIVNGVAGSGKTTIA
LHRVAYLLYNYRNQIQDKVLILGPNNIFVDYISEVLPSLGENGVKQTTFKDFIEDLLPTNNFLEYDNYIERFIKKDNEFI
EDIAYKQSKAYMEDLDSFMEDLERNIFITEDVILMEEVAIDKKEIDEMLHSYYKYMPLFKRSRKIKRIVFSKIRDVRNKK
VYETQRQYEEKLKKLSEEELQLNKNNLEFERKNNIRNIVRKSMELKKSLVWLDNPQVLDIYNEFNNNNKLTVDDIIAILY
LKIKLEGLRYRNEIKHIVIDEAQDYSFLQFVVLKELTDCQSITIVGDVNQRTLPCKDEVPMLCLDSVFNRVDVEYFNLDK
SYRSTKEIIEYANKHLKTNKIVPLVREGDPVKEVTVKNSREAIDKVNYYLSYLENKGYENIAIITTTLEQGKVIGSELKK
QMYINLIEREDIIYSGGKIIIPSYLSKGLEFDATILILDDNNIGENLKYIMATRALHEMIVVHKEGKKL

Sequences:

>Translated_709_residues
MDNNQINNSMDKYIELSMEREYLDFIIDKVRKETGIYLDKRKDIVKDIVEYRKEFLEEDKNDEDKVAEYFDHERYLKEKL
YGFTDKKLKELTILEQNPYFGKVNFIDEGDEDSIYIGRYGFLETGNYKPFIVDWRAPICQIFYQGKLGNIAYESPDGKIE
VDVKSKRQYVIRKGILKGMFDSALDVKDEVLQMILSENTKEKLKDIVMTIQEEQDNLIRQPKDKAMIVNGVAGSGKTTIA
LHRVAYLLYNYRNQIQDKVLILGPNNIFVDYISEVLPSLGENGVKQTTFKDFIEDLLPTNNFLEYDNYIERFIKKDNEFI
EDIAYKQSKAYMEDLDSFMEDLERNIFITEDVILMEEVAIDKKEIDEMLHSYYKYMPLFKRSRKIKRIVFSKIRDVRNKK
VYETQRQYEEKLKKLSEEELQLNKNNLEFERKNNIRNIVRKSMELKKSLVWLDNPQVLDIYNEFNNNNKLTVDDIIAILY
LKIKLEGLRYRNEIKHIVIDEAQDYSFLQFVVLKELTDCQSITIVGDVNQRTLPCKDEVPMLCLDSVFNRVDVEYFNLDK
SYRSTKEIIEYANKHLKTNKIVPLVREGDPVKEVTVKNSREAIDKVNYYLSYLENKGYENIAIITTTLEQGKVIGSELKK
QMYINLIEREDIIYSGGKIIIPSYLSKGLEFDATILILDDNNIGENLKYIMATRALHEMIVVHKEGKKL
>Mature_709_residues
MDNNQINNSMDKYIELSMEREYLDFIIDKVRKETGIYLDKRKDIVKDIVEYRKEFLEEDKNDEDKVAEYFDHERYLKEKL
YGFTDKKLKELTILEQNPYFGKVNFIDEGDEDSIYIGRYGFLETGNYKPFIVDWRAPICQIFYQGKLGNIAYESPDGKIE
VDVKSKRQYVIRKGILKGMFDSALDVKDEVLQMILSENTKEKLKDIVMTIQEEQDNLIRQPKDKAMIVNGVAGSGKTTIA
LHRVAYLLYNYRNQIQDKVLILGPNNIFVDYISEVLPSLGENGVKQTTFKDFIEDLLPTNNFLEYDNYIERFIKKDNEFI
EDIAYKQSKAYMEDLDSFMEDLERNIFITEDVILMEEVAIDKKEIDEMLHSYYKYMPLFKRSRKIKRIVFSKIRDVRNKK
VYETQRQYEEKLKKLSEEELQLNKNNLEFERKNNIRNIVRKSMELKKSLVWLDNPQVLDIYNEFNNNNKLTVDDIIAILY
LKIKLEGLRYRNEIKHIVIDEAQDYSFLQFVVLKELTDCQSITIVGDVNQRTLPCKDEVPMLCLDSVFNRVDVEYFNLDK
SYRSTKEIIEYANKHLKTNKIVPLVREGDPVKEVTVKNSREAIDKVNYYLSYLENKGYENIAIITTTLEQGKVIGSELKK
QMYINLIEREDIIYSGGKIIIPSYLSKGLEFDATILILDDNNIGENLKYIMATRALHEMIVVHKEGKKL

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 83627; Mature: 83627

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNNQINNSMDKYIELSMEREYLDFIIDKVRKETGIYLDKRKDIVKDIVEYRKEFLEEDK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHCCC
NDEDKVAEYFDHERYLKEKLYGFTDKKLKELTILEQNPYFGKVNFIDEGDEDSIYIGRYG
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEEECCCCEEEEEECCCCCCCCEEEEEEE
FLETGNYKPFIVDWRAPICQIFYQGKLGNIAYESPDGKIEVDVKSKRQYVIRKGILKGMF
EEECCCCCCEEEECCCHHHHHHHCCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHHHHH
DSALDVKDEVLQMILSENTKEKLKDIVMTIQEEQDNLIRQPKDKAMIVNGVAGSGKTTIA
HHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
LHRVAYLLYNYRNQIQDKVLILGPNNIFVDYISEVLPSLGENGVKQTTFKDFIEDLLPTN
HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
NFLEYDNYIERFIKKDNEFIEDIAYKQSKAYMEDLDSFMEDLERNIFITEDVILMEEVAI
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHC
DKKEIDEMLHSYYKYMPLFKRSRKIKRIVFSKIRDVRNKKVYETQRQYEEKLKKLSEEEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHH
QLNKNNLEFERKNNIRNIVRKSMELKKSLVWLDNPQVLDIYNEFNNNNKLTVDDIIAILY
HCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHHCCCCCEEHHHHHHHHH
LKIKLEGLRYRNEIKHIVIDEAQDYSFLQFVVLKELTDCQSITIVGDVNQRTLPCKDEVP
HHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
MLCLDSVFNRVDVEYFNLDKSYRSTKEIIEYANKHLKTNKIVPLVREGDPVKEVTVKNSR
HHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHCCCCHH
EAIDKVNYYLSYLENKGYENIAIITTTLEQGKVIGSELKKQMYINLIEREDIIYSGGKII
HHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHCCCEEECCCCEE
IPSYLSKGLEFDATILILDDNNIGENLKYIMATRALHEMIVVHKEGKKL
ECHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHEECCCCCC
>Mature Secondary Structure
MDNNQINNSMDKYIELSMEREYLDFIIDKVRKETGIYLDKRKDIVKDIVEYRKEFLEEDK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHCCC
NDEDKVAEYFDHERYLKEKLYGFTDKKLKELTILEQNPYFGKVNFIDEGDEDSIYIGRYG
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEEECCCCEEEEEECCCCCCCCEEEEEEE
FLETGNYKPFIVDWRAPICQIFYQGKLGNIAYESPDGKIEVDVKSKRQYVIRKGILKGMF
EEECCCCCCEEEECCCHHHHHHHCCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHHHHH
DSALDVKDEVLQMILSENTKEKLKDIVMTIQEEQDNLIRQPKDKAMIVNGVAGSGKTTIA
HHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
LHRVAYLLYNYRNQIQDKVLILGPNNIFVDYISEVLPSLGENGVKQTTFKDFIEDLLPTN
HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
NFLEYDNYIERFIKKDNEFIEDIAYKQSKAYMEDLDSFMEDLERNIFITEDVILMEEVAI
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHC
DKKEIDEMLHSYYKYMPLFKRSRKIKRIVFSKIRDVRNKKVYETQRQYEEKLKKLSEEEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHH
QLNKNNLEFERKNNIRNIVRKSMELKKSLVWLDNPQVLDIYNEFNNNNKLTVDDIIAILY
HCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHHCCCCCEEHHHHHHHHH
LKIKLEGLRYRNEIKHIVIDEAQDYSFLQFVVLKELTDCQSITIVGDVNQRTLPCKDEVP
HHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
MLCLDSVFNRVDVEYFNLDKSYRSTKEIIEYANKHLKTNKIVPLVREGDPVKEVTVKNSR
HHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHCCCCHH
EAIDKVNYYLSYLENKGYENIAIITTTLEQGKVIGSELKKQMYINLIEREDIIYSGGKII
HHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHCCCEEECCCCEE
IPSYLSKGLEFDATILILDDNNIGENLKYIMATRALHEMIVVHKEGKKL
ECHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]