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The map label for this gene is treC [H]

Identifier: 226949286

GI number: 226949286

Start: 2271774

End: 2273441

Strand: Direct

Name: treC [H]

Synonym: CLM_2205

Alternate gene names: 226949286

Gene position: 2271774-2273441 (Clockwise)

Preceding gene: 226949285

Following gene: 226949287

Centisome position: 54.67

GC content: 28.18

Gene sequence:

>1668_bases
ATGAAAGATTTTAAAAAAAGTGTAGTCTATCAAATCTACCCAAAATCCTTTAATGATACTAATGGTGATGGATTGGGAGA
TTTAAAAGGAATTACAGTTAAATTGGATTATTTAAAAACATTAGGTATAGATTATATATGGTTAACTCCTTTTTATATCT
CCCCTCAAAGGGATAATGGATATGATGTAGCGGATTATTGCAATATTGATCCTCTATTTGGTACCATGGAAGATTTTGAA
AATCTAGTTAGAGAAGCAAATAAAAGAGGAATTGATGTTATGCTTGATATGGTATTTAATCATACCTCTACAGAACATAA
ATGGTTTAAAAATGCTCTAAGCGGCGATAAAAAATATAAAAATTATTATATATTCAAAGAACCTAAAGATGGACAGCTCC
CTACTAACTGGAAATCTAAATTTGGAGGTCCCGCTTGGGAATATGTTAAAGAGCTTGATGAATATTACCTACATTTATTT
GATGCTACTCAAGCAGACCTTAACTGGGAAAATGAAGAAGTTAGAACAGAAGTTTTTGATATTGTGAATTTTTGGATAAA
AAAAGGTGTAAAAGGCTTTCGCTTCGATGTTATTAACCTAATTTCAAAACCAATGGAATATAAGGATGACAATAATGGAG
ATGGTCGTTCATTCTACACAGATGGTCCTAATATTCATAACCATATAAAGCAACTAAATAAAAAAACCTTTGGCAGATAT
AAAGATATAATTACTGTAGGTGAAATGTCCTCTACCACCATAGATAATTGCATTAAATATTCAAATCCTAAAGAAGAAGA
ATTGTCTATGGTATTTAATTTTCATCATCTAAAAGTAGATTATAAAGATGGTGATAAATGGAGCTTAATGAATTTTGATT
TTATAAAATTAAAAAATATCTTTAATCATTGGCAGGCTGGAATGGAAGAAGGTAATGGCTGGAATGCAGTATTTTGGTGC
AACCATGACCAACCTCGTATTGTATCTCGCTTTGGAGATGATAATAAATACCATAAAGAATCTGCAAAAATGTTAGCTAC
ATCAATACATTTACTTAGAGGGACTCCTTATATTTATCAGGGAGAAGAAATCGGTATGACAAATTGTTATTATGATACAA
TTAATTCCTATAGGGATGTGGAATCAATTAATTTTTATAATATACTAAAGTCTGAAGGTAAAACTGAAGAAGAAATAATT
AAAATTTTACAGGCAAAATCAAGAGATAATTCCCGTAGTCCAATGCAATGGGATAACTCAAACAATGCTGGTTTTACTAA
AGAAGATCCTTGGATAAAAGTATGCAAAAACTATAAAGATATCAATGTAGAAAATTCCTTAAAAGATAAAGATTCAGTTT
TTTATCATTATCAAAAACTGATTAAGTTAAGAAAGGAATATGATATTATATCTTATGGAAATTTTGAATTAATACTAAAA
GAAGACAAAAGTATATTTGCTTATTTAAGAAACTACAAAAATGAAAAACTACTTGTAATAAATAATTTTTATGGAAAAGA
AATCTTATTTAAATCGCCTATAGAATTTAAATTAGGTGAATATAAAAACAAAATTTTAATTTCTAATTATAAGGATTCCC
CTATAGACTTTAGAAAAATTAATTTAAGACCTTATGAGTCTATAGTTTACCATCTTGAGAGAAAATAA

Upstream 100 bases:

>100_bases
GAGTAAAAAAATACAATAAACCAATTATATCCTAAAATAGAAAAGGAGGATTAAATTCCTTCCTTTTCTAATTCATATTT
AAACAAAAGGAGCAAATTAC

Downstream 100 bases:

>100_bases
AAAAAATGTTAAAATGTTTCTGGTGATAAGATATGGAAAGCAAATATTTGACTATTTATAATGAGATTTCAAATAAAATA
GAAAATAATAAAATTCAATC

Product: alpha,alpha-phosphotrehalase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MKDFKKSVVYQIYPKSFNDTNGDGLGDLKGITVKLDYLKTLGIDYIWLTPFYISPQRDNGYDVADYCNIDPLFGTMEDFE
NLVREANKRGIDVMLDMVFNHTSTEHKWFKNALSGDKKYKNYYIFKEPKDGQLPTNWKSKFGGPAWEYVKELDEYYLHLF
DATQADLNWENEEVRTEVFDIVNFWIKKGVKGFRFDVINLISKPMEYKDDNNGDGRSFYTDGPNIHNHIKQLNKKTFGRY
KDIITVGEMSSTTIDNCIKYSNPKEEELSMVFNFHHLKVDYKDGDKWSLMNFDFIKLKNIFNHWQAGMEEGNGWNAVFWC
NHDQPRIVSRFGDDNKYHKESAKMLATSIHLLRGTPYIYQGEEIGMTNCYYDTINSYRDVESINFYNILKSEGKTEEEII
KILQAKSRDNSRSPMQWDNSNNAGFTKEDPWIKVCKNYKDINVENSLKDKDSVFYHYQKLIKLRKEYDIISYGNFELILK
EDKSIFAYLRNYKNEKLLVINNFYGKEILFKSPIEFKLGEYKNKILISNYKDSPIDFRKINLRPYESIVYHLERK

Sequences:

>Translated_555_residues
MKDFKKSVVYQIYPKSFNDTNGDGLGDLKGITVKLDYLKTLGIDYIWLTPFYISPQRDNGYDVADYCNIDPLFGTMEDFE
NLVREANKRGIDVMLDMVFNHTSTEHKWFKNALSGDKKYKNYYIFKEPKDGQLPTNWKSKFGGPAWEYVKELDEYYLHLF
DATQADLNWENEEVRTEVFDIVNFWIKKGVKGFRFDVINLISKPMEYKDDNNGDGRSFYTDGPNIHNHIKQLNKKTFGRY
KDIITVGEMSSTTIDNCIKYSNPKEEELSMVFNFHHLKVDYKDGDKWSLMNFDFIKLKNIFNHWQAGMEEGNGWNAVFWC
NHDQPRIVSRFGDDNKYHKESAKMLATSIHLLRGTPYIYQGEEIGMTNCYYDTINSYRDVESINFYNILKSEGKTEEEII
KILQAKSRDNSRSPMQWDNSNNAGFTKEDPWIKVCKNYKDINVENSLKDKDSVFYHYQKLIKLRKEYDIISYGNFELILK
EDKSIFAYLRNYKNEKLLVINNFYGKEILFKSPIEFKLGEYKNKILISNYKDSPIDFRKINLRPYESIVYHLERK
>Mature_555_residues
MKDFKKSVVYQIYPKSFNDTNGDGLGDLKGITVKLDYLKTLGIDYIWLTPFYISPQRDNGYDVADYCNIDPLFGTMEDFE
NLVREANKRGIDVMLDMVFNHTSTEHKWFKNALSGDKKYKNYYIFKEPKDGQLPTNWKSKFGGPAWEYVKELDEYYLHLF
DATQADLNWENEEVRTEVFDIVNFWIKKGVKGFRFDVINLISKPMEYKDDNNGDGRSFYTDGPNIHNHIKQLNKKTFGRY
KDIITVGEMSSTTIDNCIKYSNPKEEELSMVFNFHHLKVDYKDGDKWSLMNFDFIKLKNIFNHWQAGMEEGNGWNAVFWC
NHDQPRIVSRFGDDNKYHKESAKMLATSIHLLRGTPYIYQGEEIGMTNCYYDTINSYRDVESINFYNILKSEGKTEEEII
KILQAKSRDNSRSPMQWDNSNNAGFTKEDPWIKVCKNYKDINVENSLKDKDSVFYHYQKLIKLRKEYDIISYGNFELILK
EDKSIFAYLRNYKNEKLLVINNFYGKEILFKSPIEFKLGEYKNKILISNYKDSPIDFRKINLRPYESIVYHLERK

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=534, Percent_Identity=30.1498127340824, Blast_Score=228, Evalue=9e-60,
Organism=Escherichia coli, GI1790687, Length=549, Percent_Identity=51.3661202185792, Blast_Score=613, Evalue=1e-177,
Organism=Escherichia coli, GI1786604, Length=217, Percent_Identity=26.2672811059908, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1789995, Length=179, Percent_Identity=29.608938547486, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25147709, Length=593, Percent_Identity=23.7774030354132, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI32565753, Length=201, Percent_Identity=26.865671641791, Blast_Score=87, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322245, Length=578, Percent_Identity=39.4463667820069, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321726, Length=580, Percent_Identity=37.9310344827586, Blast_Score=360, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6322241, Length=580, Percent_Identity=37.2413793103448, Blast_Score=347, Evalue=4e-96,
Organism=Saccharomyces cerevisiae, GI6322021, Length=580, Percent_Identity=37.2413793103448, Blast_Score=347, Evalue=4e-96,
Organism=Saccharomyces cerevisiae, GI6324416, Length=580, Percent_Identity=37.2413793103448, Blast_Score=346, Evalue=4e-96,
Organism=Saccharomyces cerevisiae, GI6321731, Length=576, Percent_Identity=38.0208333333333, Blast_Score=343, Evalue=3e-95,
Organism=Saccharomyces cerevisiae, GI6319776, Length=576, Percent_Identity=37.8472222222222, Blast_Score=342, Evalue=8e-95,
Organism=Drosophila melanogaster, GI24583745, Length=527, Percent_Identity=33.5863377609108, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24583747, Length=532, Percent_Identity=34.7744360902256, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24583749, Length=532, Percent_Identity=34.5864661654135, Blast_Score=258, Evalue=7e-69,
Organism=Drosophila melanogaster, GI24586593, Length=536, Percent_Identity=30.9701492537313, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24586599, Length=589, Percent_Identity=30.0509337860781, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI221330053, Length=591, Percent_Identity=30.9644670050761, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24586591, Length=593, Percent_Identity=31.8718381112985, Blast_Score=250, Evalue=2e-66,
Organism=Drosophila melanogaster, GI45549022, Length=524, Percent_Identity=33.587786259542, Blast_Score=248, Evalue=8e-66,
Organism=Drosophila melanogaster, GI24586589, Length=495, Percent_Identity=34.7474747474747, Blast_Score=247, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24586597, Length=489, Percent_Identity=32.5153374233129, Blast_Score=241, Evalue=8e-64,
Organism=Drosophila melanogaster, GI24586587, Length=589, Percent_Identity=29.3718166383701, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI281360393, Length=479, Percent_Identity=28.39248434238, Blast_Score=191, Evalue=9e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 65711; Mature: 65711

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDFKKSVVYQIYPKSFNDTNGDGLGDLKGITVKLDYLKTLGIDYIWLTPFYISPQRDNG
CCCHHHCCEEEECCCCCCCCCCCCCCCCCEEEEEEEEHHHCCCCEEEEEEEEECCCCCCC
YDVADYCNIDPLFGTMEDFENLVREANKRGIDVMLDMVFNHTSTEHKWFKNALSGDKKYK
CCHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
NYYIFKEPKDGQLPTNWKSKFGGPAWEYVKELDEYYLHLFDATQADLNWENEEVRTEVFD
CEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
IVNFWIKKGVKGFRFDVINLISKPMEYKDDNNGDGRSFYTDGPNIHNHIKQLNKKTFGRY
HHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHH
KDIITVGEMSSTTIDNCIKYSNPKEEELSMVFNFHHLKVDYKDGDKWSLMNFDFIKLKNI
HHEEEECCCCCHHHHHHHHCCCCCHHHHHHEEEEEEEEEEECCCCEEEECCCHHHHHHHH
FNHWQAGMEEGNGWNAVFWCNHDQPRIVSRFGDDNKYHKESAKMLATSIHLLRGTPYIYQ
HHHHHHHHCCCCCCEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
GEEIGMTNCYYDTINSYRDVESINFYNILKSEGKTEEEIIKILQAKSRDNSRSPMQWDNS
CCCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
NNAGFTKEDPWIKVCKNYKDINVENSLKDKDSVFYHYQKLIKLRKEYDIISYGNFELILK
CCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCEEEEEE
EDKSIFAYLRNYKNEKLLVINNFYGKEILFKSPIEFKLGEYKNKILISNYKDSPIDFRKI
CCHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCEECCCCCCEEEEECCCCCCCCEEEE
NLRPYESIVYHLERK
CCCHHHHHHHHHCCC
>Mature Secondary Structure
MKDFKKSVVYQIYPKSFNDTNGDGLGDLKGITVKLDYLKTLGIDYIWLTPFYISPQRDNG
CCCHHHCCEEEECCCCCCCCCCCCCCCCCEEEEEEEEHHHCCCCEEEEEEEEECCCCCCC
YDVADYCNIDPLFGTMEDFENLVREANKRGIDVMLDMVFNHTSTEHKWFKNALSGDKKYK
CCHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
NYYIFKEPKDGQLPTNWKSKFGGPAWEYVKELDEYYLHLFDATQADLNWENEEVRTEVFD
CEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
IVNFWIKKGVKGFRFDVINLISKPMEYKDDNNGDGRSFYTDGPNIHNHIKQLNKKTFGRY
HHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHH
KDIITVGEMSSTTIDNCIKYSNPKEEELSMVFNFHHLKVDYKDGDKWSLMNFDFIKLKNI
HHEEEECCCCCHHHHHHHHCCCCCHHHHHHEEEEEEEEEEECCCCEEEECCCHHHHHHHH
FNHWQAGMEEGNGWNAVFWCNHDQPRIVSRFGDDNKYHKESAKMLATSIHLLRGTPYIYQ
HHHHHHHHCCCCCCEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
GEEIGMTNCYYDTINSYRDVESINFYNILKSEGKTEEEIIKILQAKSRDNSRSPMQWDNS
CCCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
NNAGFTKEDPWIKVCKNYKDINVENSLKDKDSVFYHYQKLIKLRKEYDIISYGNFELILK
CCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCEEEEEE
EDKSIFAYLRNYKNEKLLVINNFYGKEILFKSPIEFKLGEYKNKILISNYKDSPIDFRKI
CCHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCEECCCCCCEEEEECCCCCCCCEEEE
NLRPYESIVYHLERK
CCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7651129; 8969503; 9384377; 7751281 [H]