| Definition | Clostridium botulinum A2 str. Kyoto chromosome, complete genome. |
|---|---|
| Accession | NC_012563 |
| Length | 4,155,278 |
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The map label for this gene is treP [H]
Identifier: 226949285
GI number: 226949285
Start: 2270265
End: 2271692
Strand: Direct
Name: treP [H]
Synonym: CLM_2204
Alternate gene names: 226949285
Gene position: 2270265-2271692 (Clockwise)
Preceding gene: 226949284
Following gene: 226949286
Centisome position: 54.64
GC content: 33.54
Gene sequence:
>1428_bases ATGTCTAAGTTTTCAAATGACGTACAGCAATTATTAGAATATATTGGGGGAAAAGAGAATATTTCCGCAGTAACCCATTG TGCAACCCGTATGCGTTTTGTACTACAGGATGTTAAAAAAGCAGATATTAAAAACATTGAAAAAATTAAATCTGTAAAGG GAGTTTTTACACAGGCTGGTCAATTTCAGGTCATTGTAGGAAATGAAGTTTCAACATTTTATAATGAATTTGTAAAAATA GCTAAAGTAGACGGCGTTAGTAAAGATCAAGCCAAAGTAGCTGCTAAAAACAATATGAATTTTATGCAAAAGCTACTAGC TAATTTAGCAGAAATATTCGCTCCTATTATACCTGCTCTTATAGTTGGAGGCCTAATATTAGGATTCCGTAATATTATTG GAGATATTAAATTAGTGGAAAATGGAACTAAAACTTTAATACAAGTATCTCAATTTTGGCAAGGTGTTCATTCCTTCTTA TGGTTAATTGGCGAAGCAATATTCTTCTTCTTACCTGTTGGAATAACTTGGTCTATTTCTAAAAAGATGGGCACCACACA AATTTTAGGAATCATATTAGGACTTACTCTAGTTTCTCCTCAACTATTAAATGCTTATTCTGCTGCAGGTACTCCTGTAG ATAAAATTCCAGTATGGAACTTCGGTTTTGCAAAAATTCAAATGATTGGTTATCAAGCACAAGTAATTCCATCAATGCTA GCAGGATTCCTTTTAGCCTGGTTAGAAAAATCTATGCGAAAAATTGTACCAGAATATATTTCCATGATTTTAGTACCTTT TCTTTCGCTAGTACCTACTGTATTAATAGCTCATACTATTTTAGGACCAGTAGGCTGGAAAATAGGTACAGTTATAGCAA ACGTAGTATATTCAAGTTTAACTTCAACCTTTGGCTGGCTATTTGCGGCTGTATTTGGATTTACCTATGCGCCTTTAGTT ATTACAGGATTACATCATATGACTAACGCTATTGATCTACAAATAATGGCCGAACTTGGTGGAACTAATTTATGGCCAAT GATTGCCCTATCCAATATAGCTCAGGGCTCTGCAGTTTTAGCAATGATTTATTTAAATAAAAATAACGAAGAAGAAAAAC AGGTATCTATTCCCGCAGCAATCTCCTGTTATCTAGGGGTAACGGAGCCAGCTATATTTGGTATAAATCTAAAGTATATA TTCCCTTTTTTAGCTGCTATGATAGGTTCTTCAATAGCCGCAGTAATATCAGTAGGTTCAAACGTTATGGCTAATTCAAT TGGAGTTGGTGGTCTACCAGGTATACTGTCAATAAAACCACAATACATGTTATCTTTTGCATTAGCAATGTTAGTAGCTA TTGTTGTACCTTTTATACTTACAATTGTGTTTTCTAAGAAAAAAAAGTGGAGTAAAAAAATACAATAA
Upstream 100 bases:
>100_bases TACGTACAAGATATAATTTATTTATCGCACTTGTACGTACATCTTTCTGATAAATAAAAATATTTACGAAAGTATAAATA ATAAAGGGGGATTATTTAAT
Downstream 100 bases:
>100_bases ACCAATTATATCCTAAAATAGAAAAGGAGGATTAAATTCCTTCCTTTTCTAATTCATATTTAAACAAAAGGAGCAAATTA CATGAAAGATTTTAAAAAAA
Product: PTS system trehalose-specific transporter subunit IIBC
Products: NA
Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]
Number of amino acids: Translated: 475; Mature: 474
Protein sequence:
>475_residues MSKFSNDVQQLLEYIGGKENISAVTHCATRMRFVLQDVKKADIKNIEKIKSVKGVFTQAGQFQVIVGNEVSTFYNEFVKI AKVDGVSKDQAKVAAKNNMNFMQKLLANLAEIFAPIIPALIVGGLILGFRNIIGDIKLVENGTKTLIQVSQFWQGVHSFL WLIGEAIFFFLPVGITWSISKKMGTTQILGIILGLTLVSPQLLNAYSAAGTPVDKIPVWNFGFAKIQMIGYQAQVIPSML AGFLLAWLEKSMRKIVPEYISMILVPFLSLVPTVLIAHTILGPVGWKIGTVIANVVYSSLTSTFGWLFAAVFGFTYAPLV ITGLHHMTNAIDLQIMAELGGTNLWPMIALSNIAQGSAVLAMIYLNKNNEEEKQVSIPAAISCYLGVTEPAIFGINLKYI FPFLAAMIGSSIAAVISVGSNVMANSIGVGGLPGILSIKPQYMLSFALAMLVAIVVPFILTIVFSKKKKWSKKIQ
Sequences:
>Translated_475_residues MSKFSNDVQQLLEYIGGKENISAVTHCATRMRFVLQDVKKADIKNIEKIKSVKGVFTQAGQFQVIVGNEVSTFYNEFVKI AKVDGVSKDQAKVAAKNNMNFMQKLLANLAEIFAPIIPALIVGGLILGFRNIIGDIKLVENGTKTLIQVSQFWQGVHSFL WLIGEAIFFFLPVGITWSISKKMGTTQILGIILGLTLVSPQLLNAYSAAGTPVDKIPVWNFGFAKIQMIGYQAQVIPSML AGFLLAWLEKSMRKIVPEYISMILVPFLSLVPTVLIAHTILGPVGWKIGTVIANVVYSSLTSTFGWLFAAVFGFTYAPLV ITGLHHMTNAIDLQIMAELGGTNLWPMIALSNIAQGSAVLAMIYLNKNNEEEKQVSIPAAISCYLGVTEPAIFGINLKYI FPFLAAMIGSSIAAVISVGSNVMANSIGVGGLPGILSIKPQYMLSFALAMLVAIVVPFILTIVFSKKKKWSKKIQ >Mature_474_residues SKFSNDVQQLLEYIGGKENISAVTHCATRMRFVLQDVKKADIKNIEKIKSVKGVFTQAGQFQVIVGNEVSTFYNEFVKIA KVDGVSKDQAKVAAKNNMNFMQKLLANLAEIFAPIIPALIVGGLILGFRNIIGDIKLVENGTKTLIQVSQFWQGVHSFLW LIGEAIFFFLPVGITWSISKKMGTTQILGIILGLTLVSPQLLNAYSAAGTPVDKIPVWNFGFAKIQMIGYQAQVIPSMLA GFLLAWLEKSMRKIVPEYISMILVPFLSLVPTVLIAHTILGPVGWKIGTVIANVVYSSLTSTFGWLFAAVFGFTYAPLVI TGLHHMTNAIDLQIMAELGGTNLWPMIALSNIAQGSAVLAMIYLNKNNEEEKQVSIPAAISCYLGVTEPAIFGINLKYIF PFLAAMIGSSIAAVISVGSNVMANSIGVGGLPGILSIKPQYMLSFALAMLVAIVVPFILTIVFSKKKKWSKKIQ
Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This
COG id: COG1263
COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIC type-1 domain [H]
Homologues:
Organism=Escherichia coli, GI2367362, Length=470, Percent_Identity=52.3404255319149, Blast_Score=462, Evalue=1e-131, Organism=Escherichia coli, GI48994906, Length=467, Percent_Identity=28.9079229122056, Blast_Score=166, Evalue=2e-42, Organism=Escherichia coli, GI1790159, Length=415, Percent_Identity=25.7831325301205, Blast_Score=149, Evalue=4e-37, Organism=Escherichia coli, GI1788769, Length=494, Percent_Identity=24.4939271255061, Blast_Score=118, Evalue=7e-28,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR018113 - InterPro: IPR004719 - InterPro: IPR001996 - InterPro: IPR003352 - InterPro: IPR013013 - InterPro: IPR011535 - InterPro: IPR011296 [H]
Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 51687; Mature: 51556
Theoretical pI: Translated: 10.10; Mature: 10.10
Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.6 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 3.4 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSKFSNDVQQLLEYIGGKENISAVTHCATRMRFVLQDVKKADIKNIEKIKSVKGVFTQAG CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC QFQVIVGNEVSTFYNEFVKIAKVDGVSKDQAKVAAKNNMNFMQKLLANLAEIFAPIIPAL CEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH IVGGLILGFRNIIGDIKLVENGTKTLIQVSQFWQGVHSFLWLIGEAIFFFLPVGITWSIS HHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEH KKMGTTQILGIILGLTLVSPQLLNAYSAAGTPVDKIPVWNFGFAKIQMIGYQAQVIPSML HHCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCHHHHHEECHHHHHHHHHH AGFLLAWLEKSMRKIVPEYISMILVPFLSLVPTVLIAHTILGPVGWKIGTVIANVVYSSL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH TSTFGWLFAAVFGFTYAPLVITGLHHMTNAIDLQIMAELGGTNLWPMIALSNIAQGSAVL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEE AMIYLNKNNEEEKQVSIPAAISCYLGVTEPAIFGINLKYIFPFLAAMIGSSIAAVISVGS EEEEECCCCCHHHHCCCCHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCC NVMANSIGVGGLPGILSIKPQYMLSFALAMLVAIVVPFILTIVFSKKKKWSKKIQ HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure SKFSNDVQQLLEYIGGKENISAVTHCATRMRFVLQDVKKADIKNIEKIKSVKGVFTQAG CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC QFQVIVGNEVSTFYNEFVKIAKVDGVSKDQAKVAAKNNMNFMQKLLANLAEIFAPIIPAL CEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH IVGGLILGFRNIIGDIKLVENGTKTLIQVSQFWQGVHSFLWLIGEAIFFFLPVGITWSIS HHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEH KKMGTTQILGIILGLTLVSPQLLNAYSAAGTPVDKIPVWNFGFAKIQMIGYQAQVIPSML HHCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCHHHHHEECHHHHHHHHHH AGFLLAWLEKSMRKIVPEYISMILVPFLSLVPTVLIAHTILGPVGWKIGTVIANVVYSSL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH TSTFGWLFAAVFGFTYAPLVITGLHHMTNAIDLQIMAELGGTNLWPMIALSNIAQGSAVL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEE AMIYLNKNNEEEKQVSIPAAISCYLGVTEPAIFGINLKYIFPFLAAMIGSSIAAVISVGS EEEEECCCCCHHHHCCCCHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCC NVMANSIGVGGLPGILSIKPQYMLSFALAMLVAIVVPFILTIVFSKKKKWSKKIQ HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7608078; 7610040; 9278503 [H]