Click here to switch to the map view.

The map label for this gene is ywjB [H]

Identifier: 226225119

GI number: 226225119

Start: 2621544

End: 2622068

Strand: Reverse

Name: ywjB [H]

Synonym: Lm4b_02540

Alternate gene names: 226225119

Gene position: 2622068-2621544 (Counterclockwise)

Preceding gene: 226225120

Following gene: 226225118

Centisome position: 90.02

GC content: 40.38

Gene sequence:

>525_bases
ATGAGTGAAAAACAAGTTGCGCTATATATCGCGGTTAGTTTGGACGGTTATATTGCAGATGAAAACGGAAGTGTCGAATG
GTTAGAATCTATTGATAGTGAAGGGGATGCGGGTTATGAAGCTTTCTTTGACAACGTAGATACAGTTGTAATGGGCCGGA
CGACGTATCAACAAATTTTCTCGCTTACTGACACGTTCCCTTACAGTAAAAAAGATGTCTACGTTTTTTCCAACACGAAA
GCTGGGACAAAAGATGAGTACGCTGACTTTGTAGCTGGGACTGTTGATACATGGCTGAATAACATTGATGGTGAAAAAAT
CTGGCTTGTAGGTGGCGCAAAATTAGTGCAACAATTTTTAAAAGAGAAGGCGATAGATCGGTTTGTGATAACGATTGCGC
CCATTATTTTAGGAAAAGGAATTCCACTCTTTGAAGAAGATAGAGAGCACGCGCTAGAGCTAGAAGAAGTAACTCGTTTC
GGCCAGTTTGCCCAACTAACGTATAAAAACTTGGAGGAAAATTAA

Upstream 100 bases:

>100_bases
TTTTATCACCCGTGAACGCGGCGACAATAGAAGAAGCTCACAAAATTATCTCATCCGGAAAAATGATTGGAAAATTAGTA
GTGAAAGGATTTGAGTAATA

Downstream 100 bases:

>100_bases
ATGAAAATTGCTGCTTTTGATATTGATGCACAAAAAGGTTTTACGCCGCTTTGTCCCGATGAATTACCGGTTTCGGGCGG
AGACAAAATTGTGCCAGAAC

Product: Chain A, Dihydrofolate Reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MSEKQVALYIAVSLDGYIADENGSVEWLESIDSEGDAGYEAFFDNVDTVVMGRTTYQQIFSLTDTFPYSKKDVYVFSNTK
AGTKDEYADFVAGTVDTWLNNIDGEKIWLVGGAKLVQQFLKEKAIDRFVITIAPIILGKGIPLFEEDREHALELEEVTRF
GQFAQLTYKNLEEN

Sequences:

>Translated_174_residues
MSEKQVALYIAVSLDGYIADENGSVEWLESIDSEGDAGYEAFFDNVDTVVMGRTTYQQIFSLTDTFPYSKKDVYVFSNTK
AGTKDEYADFVAGTVDTWLNNIDGEKIWLVGGAKLVQQFLKEKAIDRFVITIAPIILGKGIPLFEEDREHALELEEVTRF
GQFAQLTYKNLEEN
>Mature_173_residues
SEKQVALYIAVSLDGYIADENGSVEWLESIDSEGDAGYEAFFDNVDTVVMGRTTYQQIFSLTDTFPYSKKDVYVFSNTKA
GTKDEYADFVAGTVDTWLNNIDGEKIWLVGGAKLVQQFLKEKAIDRFVITIAPIILGKGIPLFEEDREHALELEEVTRFG
QFAQLTYKNLEEN

Specific function: Unknown

COG id: COG0262

COG function: function code H; Dihydrofolate reductase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis yyaP [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002734 [H]

Pfam domain/function: PF01872 RibD_C [H]

EC number: NA

Molecular weight: Translated: 19634; Mature: 19503

Theoretical pI: Translated: 4.05; Mature: 4.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKQVALYIAVSLDGYIADENGSVEWLESIDSEGDAGYEAFFDNVDTVVMGRTTYQQIF
CCCCEEEEEEEEEECCEEECCCCCHHHHHHCCCCCCCCHHHHHCCCCEEEECCHHHHHHH
SLTDTFPYSKKDVYVFSNTKAGTKDEYADFVAGTVDTWLNNIDGEKIWLVGGAKLVQQFL
HHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHH
KEKAIDRFVITIAPIILGKGIPLFEEDREHALELEEVTRFGQFAQLTYKNLEEN
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SEKQVALYIAVSLDGYIADENGSVEWLESIDSEGDAGYEAFFDNVDTVVMGRTTYQQIF
CCCEEEEEEEEEECCEEECCCCCHHHHHHCCCCCCCCHHHHHCCCCEEEECCHHHHHHH
SLTDTFPYSKKDVYVFSNTKAGTKDEYADFVAGTVDTWLNNIDGEKIWLVGGAKLVQQFL
HHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHH
KEKAIDRFVITIAPIILGKGIPLFEEDREHALELEEVTRFGQFAQLTYKNLEEN
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]