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The map label for this gene is rpoE

Identifier: 226225107

GI number: 226225107

Start: 2611243

End: 2611779

Strand: Reverse

Name: rpoE

Synonym: Lm4b_02528

Alternate gene names: 226225107

Gene position: 2611779-2611243 (Counterclockwise)

Preceding gene: 226225108

Following gene: 226225106

Centisome position: 89.67

GC content: 37.99

Gene sequence:

>537_bases
TTGGATTTAAAGAACTTAACGCAAGAAGAACGTAGTGAACTATCTTTAATTGATGTTGCACATTTTATTTTGGAACAGCG
GAAAGAAACTATTCTTTTCCCTGAATTAGTGAAAGAGATTCAAGCGTTCCTAGGTTTGAAAGATGCAGAAATAAGGGAGC
GTCTTGTTCAATTTTATACAGATATGAATATTGATGGAAACTTTATTTCACTAGGAAACAACACGTGGGGACTTCGTGCA
TGGTATCCAATGGATGCGATTGATGAAGAAGTTCAAACACAAACAACACCGAAGAAAAAACGTAAATCAGACGATGATGA
CGATGAAGATGAAGAAATCTTGGATGATGACGTGGACTACGATGATGAAGAAATCGTGGAAGAGCTTGGTGAAGAAGAAA
TTTCTCTTGCAGATGTCTTACTTGATGAAGACGAAGATGACGATGATCACTTGCCAGACGGAATCGAAGGCGACTTAGCA
ACTGTAGAAGATGATTATACGGACGGGGATTATACAGAAGACCCAGAAGATAAATAA

Upstream 100 bases:

>100_bases
TTGTACTTGCCAGAAATAACATGTAAAATAGTGAAGTTGGGCTGAACGAAAAAATAACAGCTAAATAAATTGGAATTACG
ATAGAAAGGGCGTGCCAGTT

Downstream 100 bases:

>100_bases
TAACTAATTTTAATCAGATAGATGCGTCCATTTTTGTGGAAAAGTGTCTGTCTGATTTTTTTTAGCCTACTTAATGGATT
GATGGCGGTTTCATAAAATA

Product: DNA-directed RNA polymerase subunit delta

Products: diphosphate; RNAn+1

Alternate protein names: RNAP delta factor

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MDLKNLTQEERSELSLIDVAHFILEQRKETILFPELVKEIQAFLGLKDAEIRERLVQFYTDMNIDGNFISLGNNTWGLRA
WYPMDAIDEEVQTQTTPKKKRKSDDDDDEDEEILDDDVDYDDEEIVEELGEEEISLADVLLDEDEDDDDHLPDGIEGDLA
TVEDDYTDGDYTEDPEDK

Sequences:

>Translated_178_residues
MDLKNLTQEERSELSLIDVAHFILEQRKETILFPELVKEIQAFLGLKDAEIRERLVQFYTDMNIDGNFISLGNNTWGLRA
WYPMDAIDEEVQTQTTPKKKRKSDDDDDEDEEILDDDVDYDDEEIVEELGEEEISLADVLLDEDEDDDDHLPDGIEGDLA
TVEDDYTDGDYTEDPEDK
>Mature_178_residues
MDLKNLTQEERSELSLIDVAHFILEQRKETILFPELVKEIQAFLGLKDAEIRERLVQFYTDMNIDGNFISLGNNTWGLRA
WYPMDAIDEEVQTQTTPKKKRKSDDDDDEDEEILDDDVDYDDEEIVEELGEEEISLADVLLDEDEDDDDHLPDGIEGDLA
TVEDDYTDGDYTEDPEDK

Specific function: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis

COG id: COG3343

COG function: function code K; DNA-directed RNA polymerase, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rpoE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOE_LISIN (Q927T3)

Other databases:

- EMBL:   AL596173
- PIR:   AC1770
- RefSeq:   NP_472034.1
- GeneID:   1131551
- GenomeReviews:   AL592022_GR
- KEGG:   lin:lin2705
- GenoList:   LIN2705
- HOGENOM:   HBG535252
- OMA:   TDMNTDG
- ProtClustDB:   PRK02363
- BioCyc:   LINN272626:LIN2705-MONOMER
- HAMAP:   MF_00357
- InterPro:   IPR007759
- PANTHER:   PTHR23405:SF1

Pfam domain/function: PF05066 RNA_pol_delta

EC number: 2.7.7.6

Molecular weight: Translated: 20626; Mature: 20626

Theoretical pI: Translated: 3.59; Mature: 3.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKNLTQEERSELSLIDVAHFILEQRKETILFPELVKEIQAFLGLKDAEIRERLVQFYT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
DMNIDGNFISLGNNTWGLRAWYPMDAIDEEVQTQTTPKKKRKSDDDDDEDEEILDDDVDY
CCCCCCCEEEECCCCCCEEEECCHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHCCCCCC
DDEEIVEELGEEEISLADVLLDEDEDDDDHLPDGIEGDLATVEDDYTDGDYTEDPEDK
CHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDLKNLTQEERSELSLIDVAHFILEQRKETILFPELVKEIQAFLGLKDAEIRERLVQFYT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
DMNIDGNFISLGNNTWGLRAWYPMDAIDEEVQTQTTPKKKRKSDDDDDEDEEILDDDVDY
CCCCCCCEEEECCCCCCEEEECCHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHCCCCCC
DDEEIVEELGEEEISLADVLLDEDEDDDDHLPDGIEGDLATVEDDYTDGDYTEDPEDK
CHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nucleoside triphosphate; RNAn

Specific reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669