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The map label for this gene is fbaA

Identifier: 226225103

GI number: 226225103

Start: 2604656

End: 2605510

Strand: Reverse

Name: fbaA

Synonym: Lm4b_02524

Alternate gene names: 226225103

Gene position: 2605510-2604656 (Counterclockwise)

Preceding gene: 226225104

Following gene: 226225102

Centisome position: 89.45

GC content: 41.17

Gene sequence:

>855_bases
ATGCCTATCGTTAACATGACAGACATGCTGAAAAAAGCATTAGCTGGAAAATATGCTGTTGGTCAATTCAACATCAACAA
CCTTGAATGGACTCAAGCTATTTTGAAAGCTGCAGAAGCAGAAAAAGCACCAGTTATTTTAGGGGTTTCTGAAGGAGCTG
CTAAATACATGGGAGGATTCAAAACAGTTGTAAAAATGACTGAAGGACTTGTAGAAGACCTGAAAATCACTGTACCTGTT
GCGATTCATCTTGATCATGGTTCAAGCTTTGATTCTTGTAAAGCGGCTATCGATGCAGGATTCTCTTCTGTAATGATCGA
CGGCTCTCACCACCCAATCGACGAAAACATTGCAATGACTAAACAAGTTGTTGACTATGCGCATGCTAAAGGCGTATCTG
TTGAAGCTGAAATTGGAACTGTTGGTGGAGACGAAGACGGAGTTACTGGCGGAATCAACTATGCTGATCCACAAGAATGT
TTACGTGTAGTTAAAGAAGCTAACATTGATGCACTAGCTGCAGCATTAGGTTCTGTTCACGGTCCTTACCACGGCGAACC
TGTTCTTGGTTTTGACGAAATGAAAGAAATCTCCGAACTTACAGGTGCTCCACTTGTACTTCACGGTGGTTCTGGAATTC
CTGAACACCAAATCAAAAAAGCAATTGAACTAGGTCACAGTAAAATCAACGTTAACACTGAATGCCAAATCGTTTGGACT
GCAGCTGTTCGCGAAAAATTAGCTACTGATGACAAAGTTTATGATCCACGTAAAGTAATCGGCCCTGGTGTGGACGCGAT
TATCAAAACTGTAACAGAAAAAATTCAAGAGTTTGGTTCTAACGGTAAAGCGTAA

Upstream 100 bases:

>100_bases
GTTAGGGGAAAATAGCTGCCACTATTTTTCACGGCGGAAATTCAAATCTTAGGGAAAATCAAAATGGTTTTCCTAAATTC
CTGAGGGAGGAAATTGTATT

Downstream 100 bases:

>100_bases
GACGAACTTTATGATGATATAAAAATAACTGGTAGGATCACTTGTTGATTTTACCAGTTATTTTTTATGTATCGCGAGGG
TTAGTATAGAGGGAATTTAA

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MPIVNMTDMLKKALAGKYAVGQFNINNLEWTQAILKAAEAEKAPVILGVSEGAAKYMGGFKTVVKMTEGLVEDLKITVPV
AIHLDHGSSFDSCKAAIDAGFSSVMIDGSHHPIDENIAMTKQVVDYAHAKGVSVEAEIGTVGGDEDGVTGGINYADPQEC
LRVVKEANIDALAAALGSVHGPYHGEPVLGFDEMKEISELTGAPLVLHGGSGIPEHQIKKAIELGHSKINVNTECQIVWT
AAVREKLATDDKVYDPRKVIGPGVDAIIKTVTEKIQEFGSNGKA

Sequences:

>Translated_284_residues
MPIVNMTDMLKKALAGKYAVGQFNINNLEWTQAILKAAEAEKAPVILGVSEGAAKYMGGFKTVVKMTEGLVEDLKITVPV
AIHLDHGSSFDSCKAAIDAGFSSVMIDGSHHPIDENIAMTKQVVDYAHAKGVSVEAEIGTVGGDEDGVTGGINYADPQEC
LRVVKEANIDALAAALGSVHGPYHGEPVLGFDEMKEISELTGAPLVLHGGSGIPEHQIKKAIELGHSKINVNTECQIVWT
AAVREKLATDDKVYDPRKVIGPGVDAIIKTVTEKIQEFGSNGKA
>Mature_283_residues
PIVNMTDMLKKALAGKYAVGQFNINNLEWTQAILKAAEAEKAPVILGVSEGAAKYMGGFKTVVKMTEGLVEDLKITVPVA
IHLDHGSSFDSCKAAIDAGFSSVMIDGSHHPIDENIAMTKQVVDYAHAKGVSVEAEIGTVGGDEDGVTGGINYADPQECL
RVVKEANIDALAAALGSVHGPYHGEPVLGFDEMKEISELTGAPLVLHGGSGIPEHQIKKAIELGHSKINVNTECQIVWTA
AVREKLATDDKVYDPRKVIGPGVDAIIKTVTEKIQEFGSNGKA

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=286, Percent_Identity=38.4615384615385, Blast_Score=201, Evalue=3e-53,
Organism=Escherichia coli, GI87082041, Length=287, Percent_Identity=36.2369337979094, Blast_Score=183, Evalue=8e-48,
Organism=Escherichia coli, GI1788072, Length=272, Percent_Identity=37.8676470588235, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789293, Length=339, Percent_Identity=24.7787610619469, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322790, Length=337, Percent_Identity=26.4094955489614, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 30068; Mature: 29936

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIVNMTDMLKKALAGKYAVGQFNINNLEWTQAILKAAEAEKAPVILGVSEGAAKYMGGF
CCCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHH
KTVVKMTEGLVEDLKITVPVAIHLDHGSSFDSCKAAIDAGFSSVMIDGSHHPIDENIAMT
HHHHHHHHHHHHHCEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCHHHHH
KQVVDYAHAKGVSVEAEIGTVGGDEDGVTGGINYADPQECLRVVKEANIDALAAALGSVH
HHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCC
GPYHGEPVLGFDEMKEISELTGAPLVLHGGSGIPEHQIKKAIELGHSKINVNTECQIVWT
CCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCEECCCCCEEEEEH
AAVREKLATDDKVYDPRKVIGPGVDAIIKTVTEKIQEFGSNGKA
HHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PIVNMTDMLKKALAGKYAVGQFNINNLEWTQAILKAAEAEKAPVILGVSEGAAKYMGGF
CCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHH
KTVVKMTEGLVEDLKITVPVAIHLDHGSSFDSCKAAIDAGFSSVMIDGSHHPIDENIAMT
HHHHHHHHHHHHHCEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCHHHHH
KQVVDYAHAKGVSVEAEIGTVGGDEDGVTGGINYADPQECLRVVKEANIDALAAALGSVH
HHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCC
GPYHGEPVLGFDEMKEISELTGAPLVLHGGSGIPEHQIKKAIELGHSKINVNTECQIVWT
CCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCEECCCCCEEEEEH
AAVREKLATDDKVYDPRKVIGPGVDAIIKTVTEKIQEFGSNGKA
HHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA