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The map label for this gene is mgtA [H]

Identifier: 226225102

GI number: 226225102

Start: 2603052

End: 2604335

Strand: Reverse

Name: mgtA [H]

Synonym: Lm4b_02523

Alternate gene names: 226225102

Gene position: 2604335-2603052 (Counterclockwise)

Preceding gene: 226225103

Following gene: 226225101

Centisome position: 89.41

GC content: 37.93

Gene sequence:

>1284_bases
ATGAATATAGGGATTTTTACGGATACCTACAGTCCGCAAATTAGCGGTGTAGCTACATCGATAATGATTATGGAAAACGA
ACTAAGAAAACAAGGGCACACTGTGTATATATTTACAACAACCGACCCAAACGCTGATAGAGAGAGCGAAGAGGGCCGTG
TGTTTCGTTTACCAAGTATTCCGTTTGTCTTTTTCCCAGAACGTCGCGTAGCAATTGCTGGAATGAATAAGTTTATTAAG
CTAGTAGGGCGCTTGGATTTAGATATAATTCACACACATACGGAGTTTTCATTAGGTCTATTAGGTAAGCGAATTGCTAA
AAAATATCATATTCCATCTATCCATACCTACCACACAATGTATGTCGATTACTTGCATTATATTGCGAAAGGTAAAATTT
TGACACCTTCTATGGTGGGTAAAATGACAAAATCGTTCTGTGATAGCTATGATGCCATAATCACTCCAACTGCAAAAGTA
AGGCATCACTTAGAAGAGCAAGGTATCCACAAATTAATGTACACTGTTCCAACAGGCACAGATATTTCATCGTTCGCGCC
AGTTGAAAAACAGCGAATTCTAAACTTGAAGAAACTACTTGGTATTGGAGAAAATGATCCAGTGATACTATCACTTGGAA
GAATTGCGCATGAAAAAAATATCGATGCGATTATTAATGCAATGCCAGAAGTCCTTCAAACCAAAACCACAGCCAAATTG
GTTATTGTTGGCGATGGTCCTGTGCGCAAAGACTTAGAAAAATTAGTAGAAGAAAAACAATTAGCAGATCATGTTATTTT
CACTGGTGCAGTAGACTGGGAAAATATTAGTTTATATTATCAATTAGGGGATCTGTTTGTGAGTGCTTCAACGACAGAAA
CACAAGGTTTGACTTATGCAGAAGCAATGGCCGCTTCTTTACCAGTTGTTGCCAAACGTGATGAAAGTATTGAAGGCTTT
TTAAGCGACAGAGAAACAGCCTTTTTATTCAATGAAGATGATGAGCTTGCATCACTGTTAATAAATATACTTTCAGACAA
AAATACAGCCACATTGGTCGCTACGAATGGCCGAGTAAAAGTGGAATCCATTTCTGCGGATCAATTTGGAATCAACATTG
AATCTACATACAATGAAGTTCGTGAAATATACCGAGTAAAGCGCCAAAATGGGACGATTAAAGTAAAGCCCACGCTGATA
AAAAGTAAAATAGCTTCACAAGTATTTTCACTATCATCTTCTACACACGTTCAAAGGAAAGAGAGGTCATCGCGGCGTGA
TTAA

Upstream 100 bases:

>100_bases
CCATAATGTAGTTAGTTATGTGATACGACTTACTATAGTTATGTTATAATAATATATTAAATGATGAATGAACCAACGAG
GAAGAGAGTAGGCGATAGTA

Downstream 100 bases:

>100_bases
GTTGACAATGCTATCTTCGGCAGAAAAAGTAAAAGGTCAGGGTGTGGCATCAGCTTACCGCGAACTTGTGAATTTGCTAG
AAGAACGATATAAGAATGAA

Product: human N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein

Products: NA

Alternate protein names: Guanosine diphosphomannose-dependent alpha-mannosyltransferase [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MNIGIFTDTYSPQISGVATSIMIMENELRKQGHTVYIFTTTDPNADRESEEGRVFRLPSIPFVFFPERRVAIAGMNKFIK
LVGRLDLDIIHTHTEFSLGLLGKRIAKKYHIPSIHTYHTMYVDYLHYIAKGKILTPSMVGKMTKSFCDSYDAIITPTAKV
RHHLEEQGIHKLMYTVPTGTDISSFAPVEKQRILNLKKLLGIGENDPVILSLGRIAHEKNIDAIINAMPEVLQTKTTAKL
VIVGDGPVRKDLEKLVEEKQLADHVIFTGAVDWENISLYYQLGDLFVSASTTETQGLTYAEAMAASLPVVAKRDESIEGF
LSDRETAFLFNEDDELASLLINILSDKNTATLVATNGRVKVESISADQFGINIESTYNEVREIYRVKRQNGTIKVKPTLI
KSKIASQVFSLSSSTHVQRKERSSRRD

Sequences:

>Translated_427_residues
MNIGIFTDTYSPQISGVATSIMIMENELRKQGHTVYIFTTTDPNADRESEEGRVFRLPSIPFVFFPERRVAIAGMNKFIK
LVGRLDLDIIHTHTEFSLGLLGKRIAKKYHIPSIHTYHTMYVDYLHYIAKGKILTPSMVGKMTKSFCDSYDAIITPTAKV
RHHLEEQGIHKLMYTVPTGTDISSFAPVEKQRILNLKKLLGIGENDPVILSLGRIAHEKNIDAIINAMPEVLQTKTTAKL
VIVGDGPVRKDLEKLVEEKQLADHVIFTGAVDWENISLYYQLGDLFVSASTTETQGLTYAEAMAASLPVVAKRDESIEGF
LSDRETAFLFNEDDELASLLINILSDKNTATLVATNGRVKVESISADQFGINIESTYNEVREIYRVKRQNGTIKVKPTLI
KSKIASQVFSLSSSTHVQRKERSSRRD
>Mature_427_residues
MNIGIFTDTYSPQISGVATSIMIMENELRKQGHTVYIFTTTDPNADRESEEGRVFRLPSIPFVFFPERRVAIAGMNKFIK
LVGRLDLDIIHTHTEFSLGLLGKRIAKKYHIPSIHTYHTMYVDYLHYIAKGKILTPSMVGKMTKSFCDSYDAIITPTAKV
RHHLEEQGIHKLMYTVPTGTDISSFAPVEKQRILNLKKLLGIGENDPVILSLGRIAHEKNIDAIINAMPEVLQTKTTAKL
VIVGDGPVRKDLEKLVEEKQLADHVIFTGAVDWENISLYYQLGDLFVSASTTETQGLTYAEAMAASLPVVAKRDESIEGF
LSDRETAFLFNEDDELASLLINILSDKNTATLVATNGRVKVESISADQFGINIESTYNEVREIYRVKRQNGTIKVKPTLI
KSKIASQVFSLSSSTHVQRKERSSRRD

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to GlcAGroAc2 to generate 1,2-di-O-C16/C18:1-(alpha-D- mannopyranosyl)-(1-4)-(alpha-D-glucopyranosyluronic acid)-(1-3)- glycerol(ManGlcAGroAc2) [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=335, Percent_Identity=24.4776119402985, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17532709, Length=326, Percent_Identity=24.5398773006135, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI9755344, Length=343, Percent_Identity=23.3236151603499, Blast_Score=73, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: 2.-.-.- [C]

Molecular weight: Translated: 47882; Mature: 47882

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGIFTDTYSPQISGVATSIMIMENELRKQGHTVYIFTTTDPNADRESEEGRVFRLPSI
CCCEEEECCCCCCCCCHHHEEEEEEHHHHHCCCEEEEEECCCCCCCCCCCCCCEEECCCC
PFVFFPERRVAIAGMNKFIKLVGRLDLDIIHTHTEFSLGLLGKRIAKKYHIPSIHTYHTM
CEEEECCCEEEEHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHH
YVDYLHYIAKGKILTPSMVGKMTKSFCDSYDAIITPTAKVRHHLEEQGIHKLMYTVPTGT
HHHHHHHHHCCCEECHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHCHHEEEEECCCCC
DISSFAPVEKQRILNLKKLLGIGENDPVILSLGRIAHEKNIDAIINAMPEVLQTKTTAKL
CCHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHCCHHHHHHHHHHHHCCCCCEEE
VIVGDGPVRKDLEKLVEEKQLADHVIFTGAVDWENISLYYQLGDLFVSASTTETQGLTYA
EEECCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEEEEEEEEECCCCCCCCCHHH
EAMAASLPVVAKRDESIEGFLSDRETAFLFNEDDELASLLINILSDKNTATLVATNGRVK
HHHHHCCCEEECCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCEEE
VESISADQFGINIESTYNEVREIYRVKRQNGTIKVKPTLIKSKIASQVFSLSSSTHVQRK
EEEECCCCCCCEEHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHH
ERSSRRD
HHHCCCC
>Mature Secondary Structure
MNIGIFTDTYSPQISGVATSIMIMENELRKQGHTVYIFTTTDPNADRESEEGRVFRLPSI
CCCEEEECCCCCCCCCHHHEEEEEEHHHHHCCCEEEEEECCCCCCCCCCCCCCEEECCCC
PFVFFPERRVAIAGMNKFIKLVGRLDLDIIHTHTEFSLGLLGKRIAKKYHIPSIHTYHTM
CEEEECCCEEEEHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHH
YVDYLHYIAKGKILTPSMVGKMTKSFCDSYDAIITPTAKVRHHLEEQGIHKLMYTVPTGT
HHHHHHHHHCCCEECHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHCHHEEEEECCCCC
DISSFAPVEKQRILNLKKLLGIGENDPVILSLGRIAHEKNIDAIINAMPEVLQTKTTAKL
CCHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHCCHHHHHHHHHHHHCCCCCEEE
VIVGDGPVRKDLEKLVEEKQLADHVIFTGAVDWENISLYYQLGDLFVSASTTETQGLTYA
EEECCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEEEEEEEEECCCCCCCCCHHH
EAMAASLPVVAKRDESIEGFLSDRETAFLFNEDDELASLLINILSDKNTATLVATNGRVK
HHHHHCCCEEECCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCEEE
VESISADQFGINIESTYNEVREIYRVKRQNGTIKVKPTLIKSKIASQVFSLSSSTHVQRK
EEEECCCCCCCEEHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHH
ERSSRRD
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10531370; 9634230; 12218036 [H]