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The map label for this gene is pgm

Identifier: 226225004

GI number: 226225004

Start: 2500381

End: 2501913

Strand: Reverse

Name: pgm

Synonym: Lm4b_02425

Alternate gene names: 226225004

Gene position: 2501913-2500381 (Counterclockwise)

Preceding gene: 226225005

Following gene: 226225003

Centisome position: 85.9

GC content: 40.31

Gene sequence:

>1533_bases
ATGAGTAAATCACCTGTAGCAATTATTATCCTCGATGGTTTTGGTAAACGTGCAGAAACAGTAGGTAATGCTGTAGCTCA
AGCAAACAAACCAAATTTCGACCGTTATTGGGCTAATTTTCCTCACGGGGAACTTAAAGCTGCCGGCCTTGATGTTGGTC
TTCCAGAAGGTCAAATGGGTAACTCTGAAGTTGGCCATACAAACATCGGAGCTGGACGTATTGTCTACCAAAGCTTAACT
CGTATTGACAAAGCTATTGAAGAAGGCGAATTCCAAGAGAATAAAGCCCTAAACAATGCTTTCACTCATACAAAAGAAAA
CAACTCGGACTTACATCTTTTCGGTTTACTATCAGACGGCGGCGTGCATAGTCACATTAATCACCTCGTTGCACTTTTAG
AAACTGCGAAAGATAAAGGCGTGAAAAACGTTTATATCCATGCATTCCTTGATGGACGTGACGTGGCACCACAATCCTCA
CTAGAATATTTAGAAACACTACAAAAAGCTATTAGTGACTTAAACTATGGCGCGATTGCTACTGTTTCTGGACGTTTCTA
CGCGATGGATCGTGATAAACGCTGGGAACGTGTTGAAAAAGCATACAAAGCAATCGTAAACGCTGAAGGTGAAAAATTTG
AAGATCCAATCGAACTTGTCAAAGCTTCTTATGCTAATGACAAAAATGATGAATTCGTTGTTCCAGCTATCATTACTAAA
GATGGCAAACCTGTTGCAACAGTTAAAGACAACGATGCAGTTATTTTCTTCAATTTCCGTCCTGACCGTGCGATTCAACT
TTCTAATGCATTCACTGATAAAGAATGGGATCATTTCGACCGCGGGGCTAACCACCCTAAAAACATCAAATTCGTTACAA
TGACTCTTTACAACCCAAGCATTGATGCTGAAGTTGCTTTTGAGCCAATTGAAATGAAAAATGTTATCGGCGAAGTACTT
TCTAATGAAGGCTTATCGCAACTGCGTATCGCTGAAACAGAAAAATATCCACATGTAACATTCTTTATGAATGGTGGACG
AAATGAAGAATTCCCTGGTGAAAACCGGATTCTAATCAATTCGCCAAAAGTAGAAACATACGATTTGCAACCTGAAATGA
GCGCATATGAAGTAACAGATGCACTTGTTGAAGACATTAAAAACGACAAACACGATGCGATCATCTTAAACTTCGCAAAC
CCAGATATGGTTGGTCACTCAGGTATGCTTGAGCCAACGATTAAGGCAATCGAAGCAGTAGATGAAAATCTTGGTCGTGT
AGTAGACCTTATTTTAGAAAAAGGTGGATCAGCTATTATCTTTGCGGACCATGGTAACTCTGAAACAATGTCTACTCCAG
AAGGAAAACCGCACACTGCGCACACTACTGTTCCAGTTCCAGTAATTGTAACGAAAAAAGGTGTAACGCTTCGTGAAGGT
GGTCGTCTGGCTGACGTTGCGCCAACTATGCTTGATTTACTTGGCGTTAAAAAACCTGCCGAAATGACAGGTGAAAGTTT
AATTCAAAAATAA

Upstream 100 bases:

>100_bases
GCTGATTATCTTGCAGAGTCCGACATTGACGGCGCTCTTGTAGGTGGAGCAAGCTTAGAACCAGCATCGTTCTTAGCATT
ATTGGAGGCAGTAAAATAAA

Downstream 100 bases:

>100_bases
TTTTAGTTATTACTTTAGTTTTTTTGCAAACAGAGCTACAATAAATACGAATTTAAAAACGGATGGGTCTTTGAATATGA
AGTGAATTTTTTGTTCATTT

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM [H]

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MSKSPVAIIILDGFGKRAETVGNAVAQANKPNFDRYWANFPHGELKAAGLDVGLPEGQMGNSEVGHTNIGAGRIVYQSLT
RIDKAIEEGEFQENKALNNAFTHTKENNSDLHLFGLLSDGGVHSHINHLVALLETAKDKGVKNVYIHAFLDGRDVAPQSS
LEYLETLQKAISDLNYGAIATVSGRFYAMDRDKRWERVEKAYKAIVNAEGEKFEDPIELVKASYANDKNDEFVVPAIITK
DGKPVATVKDNDAVIFFNFRPDRAIQLSNAFTDKEWDHFDRGANHPKNIKFVTMTLYNPSIDAEVAFEPIEMKNVIGEVL
SNEGLSQLRIAETEKYPHVTFFMNGGRNEEFPGENRILINSPKVETYDLQPEMSAYEVTDALVEDIKNDKHDAIILNFAN
PDMVGHSGMLEPTIKAIEAVDENLGRVVDLILEKGGSAIIFADHGNSETMSTPEGKPHTAHTTVPVPVIVTKKGVTLREG
GRLADVAPTMLDLLGVKKPAEMTGESLIQK

Sequences:

>Translated_510_residues
MSKSPVAIIILDGFGKRAETVGNAVAQANKPNFDRYWANFPHGELKAAGLDVGLPEGQMGNSEVGHTNIGAGRIVYQSLT
RIDKAIEEGEFQENKALNNAFTHTKENNSDLHLFGLLSDGGVHSHINHLVALLETAKDKGVKNVYIHAFLDGRDVAPQSS
LEYLETLQKAISDLNYGAIATVSGRFYAMDRDKRWERVEKAYKAIVNAEGEKFEDPIELVKASYANDKNDEFVVPAIITK
DGKPVATVKDNDAVIFFNFRPDRAIQLSNAFTDKEWDHFDRGANHPKNIKFVTMTLYNPSIDAEVAFEPIEMKNVIGEVL
SNEGLSQLRIAETEKYPHVTFFMNGGRNEEFPGENRILINSPKVETYDLQPEMSAYEVTDALVEDIKNDKHDAIILNFAN
PDMVGHSGMLEPTIKAIEAVDENLGRVVDLILEKGGSAIIFADHGNSETMSTPEGKPHTAHTTVPVPVIVTKKGVTLREG
GRLADVAPTMLDLLGVKKPAEMTGESLIQK
>Mature_509_residues
SKSPVAIIILDGFGKRAETVGNAVAQANKPNFDRYWANFPHGELKAAGLDVGLPEGQMGNSEVGHTNIGAGRIVYQSLTR
IDKAIEEGEFQENKALNNAFTHTKENNSDLHLFGLLSDGGVHSHINHLVALLETAKDKGVKNVYIHAFLDGRDVAPQSSL
EYLETLQKAISDLNYGAIATVSGRFYAMDRDKRWERVEKAYKAIVNAEGEKFEDPIELVKASYANDKNDEFVVPAIITKD
GKPVATVKDNDAVIFFNFRPDRAIQLSNAFTDKEWDHFDRGANHPKNIKFVTMTLYNPSIDAEVAFEPIEMKNVIGEVLS
NEGLSQLRIAETEKYPHVTFFMNGGRNEEFPGENRILINSPKVETYDLQPEMSAYEVTDALVEDIKNDKHDAIILNFANP
DMVGHSGMLEPTIKAIEAVDENLGRVVDLILEKGGSAIIFADHGNSETMSTPEGKPHTAHTTVPVPVIVTKKGVTLREGG
RLADVAPTMLDLLGVKKPAEMTGESLIQK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1790041, Length=511, Percent_Identity=49.3150684931507, Blast_Score=508, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI17507741, Length=516, Percent_Identity=44.1860465116279, Blast_Score=447, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI32564249, Length=516, Percent_Identity=44.1860465116279, Blast_Score=446, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995 [H]

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 56165; Mature: 56034

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSPVAIIILDGFGKRAETVGNAVAQANKPNFDRYWANFPHGELKAAGLDVGLPEGQMG
CCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEECCCCCCCCCCCCC
NSEVGHTNIGAGRIVYQSLTRIDKAIEEGEFQENKALNNAFTHTKENNSDLHLFGLLSDG
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCC
GVHSHINHLVALLETAKDKGVKNVYIHAFLDGRDVAPQSSLEYLETLQKAISDLNYGAIA
CHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
TVSGRFYAMDRDKRWERVEKAYKAIVNAEGEKFEDPIELVKASYANDKNDEFVVPAIITK
EECCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEEEEC
DGKPVATVKDNDAVIFFNFRPDRAIQLSNAFTDKEWDHFDRGANHPKNIKFVTMTLYNPS
CCCEEEEEECCCEEEEEEECCCCEEEECCCCCCCCCHHHHCCCCCCCCEEEEEEEEECCC
IDAEVAFEPIEMKNVIGEVLSNEGLSQLRIAETEKYPHVTFFMNGGRNEEFPGENRILIN
CCCEEEECCHHHHHHHHHHHCCCCCHHEEEECCCCCCEEEEEEECCCCCCCCCCCEEEEE
SPKVETYDLQPEMSAYEVTDALVEDIKNDKHDAIILNFANPDMVGHSGMLEPTIKAIEAV
CCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
DENLGRVVDLILEKGGSAIIFADHGNSETMSTPEGKPHTAHTTVPVPVIVTKKGVTLREG
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEECC
GRLADVAPTMLDLLGVKKPAEMTGESLIQK
CCCHHHHHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SKSPVAIIILDGFGKRAETVGNAVAQANKPNFDRYWANFPHGELKAAGLDVGLPEGQMG
CCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEECCCCCCCCCCCCC
NSEVGHTNIGAGRIVYQSLTRIDKAIEEGEFQENKALNNAFTHTKENNSDLHLFGLLSDG
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCC
GVHSHINHLVALLETAKDKGVKNVYIHAFLDGRDVAPQSSLEYLETLQKAISDLNYGAIA
CHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
TVSGRFYAMDRDKRWERVEKAYKAIVNAEGEKFEDPIELVKASYANDKNDEFVVPAIITK
EECCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEEEEC
DGKPVATVKDNDAVIFFNFRPDRAIQLSNAFTDKEWDHFDRGANHPKNIKFVTMTLYNPS
CCCEEEEEECCCEEEEEEECCCCEEEECCCCCCCCCHHHHCCCCCCCCEEEEEEEEECCC
IDAEVAFEPIEMKNVIGEVLSNEGLSQLRIAETEKYPHVTFFMNGGRNEEFPGENRILIN
CCCEEEECCHHHHHHHHHHHCCCCCHHEEEECCCCCCEEEEEEECCCCCCCCCCCEEEEE
SPKVETYDLQPEMSAYEVTDALVEDIKNDKHDAIILNFANPDMVGHSGMLEPTIKAIEAV
CCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
DENLGRVVDLILEKGGSAIIFADHGNSETMSTPEGKPHTAHTTVPVPVIVTKKGVTLREG
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEECC
GRLADVAPTMLDLLGVKKPAEMTGESLIQK
CCCHHHHHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]