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The map label for this gene is arsC [H]

Identifier: 226224838

GI number: 226224838

Start: 2326360

End: 2326785

Strand: Direct

Name: arsC [H]

Synonym: Lm4b_02257

Alternate gene names: 226224838

Gene position: 2326360-2326785 (Clockwise)

Preceding gene: 226224827

Following gene: 226224839

Centisome position: 79.87

GC content: 37.09

Gene sequence:

>426_bases
ATGACGCAAAAGCTGATCTACTTTTTATCACAAACGCATATTCGAAGTGCCATTGCTGAAGCTTGGGCGAAAAGACTTTC
ACTTAGCAATGTCAAATTCATTAGCGGTTCTTGGCATAAATCTAAATCAACACCGTTTATTGCAGAAGCGTTGAATGAGT
TTGCAATCGAGCCACCTGAAAGTTTGTCTTATTCCCCTAGCTCAGAACTACTGGCAGATGCTGATCTCATTGTAACAATT
TATGATTCTGCACATGAAACTGCACCAAAATTTCCAGCTAACATACAAGAAAAAATTATTTATTGGGACATTGATGATCC
GGAACAAGAAATAGCGTTACCAAAAAAATGGGCGAGTTATCAAGAAGTATGTGATAACATTGCCTTATCAGTAAAAAATT
TAGAGCATGTATTGATAGAGGCTTAG

Upstream 100 bases:

>100_bases
TTGTGTCTTTGGTAATAATTATCACCTATATACTGTGTACAACAAGTAATGGCAGCAAGTTTTACATGGGTACATTAATA
CGCCGGAAAGGAATTGGAAT

Downstream 100 bases:

>100_bases
ATTTCGTTGTCCCGCCATTCGTAGGCGGGACTTTTATGTTAAAAAGAAAGGAGTACATACATAATGGATGGATACAACGA
TTTAAAAAAGGCTGAAAAAG

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MTQKLIYFLSQTHIRSAIAEAWAKRLSLSNVKFISGSWHKSKSTPFIAEALNEFAIEPPESLSYSPSSELLADADLIVTI
YDSAHETAPKFPANIQEKIIYWDIDDPEQEIALPKKWASYQEVCDNIALSVKNLEHVLIEA

Sequences:

>Translated_141_residues
MTQKLIYFLSQTHIRSAIAEAWAKRLSLSNVKFISGSWHKSKSTPFIAEALNEFAIEPPESLSYSPSSELLADADLIVTI
YDSAHETAPKFPANIQEKIIYWDIDDPEQEIALPKKWASYQEVCDNIALSVKNLEHVLIEA
>Mature_140_residues
TQKLIYFLSQTHIRSAIAEAWAKRLSLSNVKFISGSWHKSKSTPFIAEALNEFAIEPPESLSYSPSSELLADADLIVTIY
DSAHETAPKFPANIQEKIIYWDIDDPEQEIALPKKWASYQEVCDNIALSVKNLEHVLIEA

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15921; Mature: 15790

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKLIYFLSQTHIRSAIAEAWAKRLSLSNVKFISGSWHKSKSTPFIAEALNEFAIEPPE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCC
SLSYSPSSELLADADLIVTIYDSAHETAPKFPANIQEKIIYWDIDDPEQEIALPKKWASY
CCCCCCCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCHHHHHH
QEVCDNIALSVKNLEHVLIEA
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQKLIYFLSQTHIRSAIAEAWAKRLSLSNVKFISGSWHKSKSTPFIAEALNEFAIEPPE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCC
SLSYSPSSELLADADLIVTIYDSAHETAPKFPANIQEKIIYWDIDDPEQEIALPKKWASY
CCCCCCCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCHHHHHH
QEVCDNIALSVKNLEHVLIEA
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]