Click here to switch to the map view.

The map label for this gene is prsA2 [H]

Identifier: 226224827

GI number: 226224827

Start: 2312776

End: 2313657

Strand: Direct

Name: prsA2 [H]

Synonym: Lm4b_02246

Alternate gene names: 226224827

Gene position: 2312776-2313657 (Clockwise)

Preceding gene: 226224826

Following gene: 226224838

Centisome position: 79.4

GC content: 36.85

Gene sequence:

>882_bases
ATGAAGAAGAAATTAATTCTTGGACTTGTCATGATGATGGCATTGTTCAGTCTAGCAGCGTGCGGTGGCGGTGGAGATGT
CGTTAAGACAGACTCTGGCGATGTAACGCAAGATGAGCTTTACGACGCAATGAAAGATAAATATGGTTCTGAGTTTGTAC
AACAACTTACTTTCGAAAAAATTCTTGGAGATAAATACAAAGTAAGCGACGAAGATGTTGATAAGAAATTCAACGAGTAT
AAATCACAATACGGAGATCAATTCTCTGCAGTTTTAGCTCAAAGTGGCTTAACGGAGAAATCATTCAAAAGCCAACTTAA
GTACAACTTGTTAGTTCAAAAAGCTACTGAAGCCAATACTGATACTAGCGACAAAACACTTAAAAAATACTATGAAACAT
GGCAACCAGATATTACTGTAAGCCATATTCTTGTAGCTGATGAAAACAAAGCCAAAGAAGTTGAACAAAAACTGAAAGAC
GGCGCAAAATTTGCTGATTTAGCAAAAGAATACTCTACAGACACTGCTACTAAAGACAATGGTGGACAATTAGCTCCATT
CGGTCCTGGTAAGATGGATCCTGCATTTGAAAAAGCAGCTTATGCCCTTAAAAACAAAGGCGACATCAGCGCTCCAGTAA
AAACACAATACGGATACCACATCATCCAAATGGACAAACCTGCAACAAAAACAACTTTCGAAAAAGATAAAAAAGCTGTA
AAAGCTTCTTACCTTGAGTCTCAACTAACTACTGAGAACATGCAAAAAACGCTTAAAAAAGAATACAAAGATGCTAACGT
AAAAGTGGAAGATAAAGACTTGAAAGATGCTTTTAAAGATTTTGATGGCTCTTCATCCAGTGAAAGCGACTCATCTAAAT
AA

Upstream 100 bases:

>100_bases
TAAATTTCTTTCATCTTTTCTTTTTACCTTTAATTTATGTTATGATAGTTATTGTGTTAAGCGGGAATTATTCCAACAAC
TAAGGAGTGTGTTTTATTTA

Downstream 100 bases:

>100_bases
GCACTAAAAAACACGCTTGGAAATTTCCAAGCGTGTTTTTTATTCAAATATAGGATTATAAAACGAACGATTATCTAACC
CAAATACTCGTTCACTGAAT

Product: post-translocation molecular chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKKKLILGLVMMMALFSLAACGGGGDVVKTDSGDVTQDELYDAMKDKYGSEFVQQLTFEKILGDKYKVSDEDVDKKFNEY
KSQYGDQFSAVLAQSGLTEKSFKSQLKYNLLVQKATEANTDTSDKTLKKYYETWQPDITVSHILVADENKAKEVEQKLKD
GAKFADLAKEYSTDTATKDNGGQLAPFGPGKMDPAFEKAAYALKNKGDISAPVKTQYGYHIIQMDKPATKTTFEKDKKAV
KASYLESQLTTENMQKTLKKEYKDANVKVEDKDLKDAFKDFDGSSSSESDSSK

Sequences:

>Translated_293_residues
MKKKLILGLVMMMALFSLAACGGGGDVVKTDSGDVTQDELYDAMKDKYGSEFVQQLTFEKILGDKYKVSDEDVDKKFNEY
KSQYGDQFSAVLAQSGLTEKSFKSQLKYNLLVQKATEANTDTSDKTLKKYYETWQPDITVSHILVADENKAKEVEQKLKD
GAKFADLAKEYSTDTATKDNGGQLAPFGPGKMDPAFEKAAYALKNKGDISAPVKTQYGYHIIQMDKPATKTTFEKDKKAV
KASYLESQLTTENMQKTLKKEYKDANVKVEDKDLKDAFKDFDGSSSSESDSSK
>Mature_293_residues
MKKKLILGLVMMMALFSLAACGGGGDVVKTDSGDVTQDELYDAMKDKYGSEFVQQLTFEKILGDKYKVSDEDVDKKFNEY
KSQYGDQFSAVLAQSGLTEKSFKSQLKYNLLVQKATEANTDTSDKTLKKYYETWQPDITVSHILVADENKAKEVEQKLKD
GAKFADLAKEYSTDTATKDNGGQLAPFGPGKMDPAFEKAAYALKNKGDISAPVKTQYGYHIIQMDKPATKTTFEKDKKAV
KASYLESQLTTENMQKTLKKEYKDANVKVEDKDLKDAFKDFDGSSSSESDSSK

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 32624; Mature: 32624

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKLILGLVMMMALFSLAACGGGGDVVKTDSGDVTQDELYDAMKDKYGSEFVQQLTFEK
CCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ILGDKYKVSDEDVDKKFNEYKSQYGDQFSAVLAQSGLTEKSFKSQLKYNLLVQKATEANT
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
DTSDKTLKKYYETWQPDITVSHILVADENKAKEVEQKLKDGAKFADLAKEYSTDTATKDN
CCHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
GGQLAPFGPGKMDPAFEKAAYALKNKGDISAPVKTQYGYHIIQMDKPATKTTFEKDKKAV
CCEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
KASYLESQLTTENMQKTLKKEYKDANVKVEDKDLKDAFKDFDGSSSSESDSSK
HHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKKKLILGLVMMMALFSLAACGGGGDVVKTDSGDVTQDELYDAMKDKYGSEFVQQLTFEK
CCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ILGDKYKVSDEDVDKKFNEYKSQYGDQFSAVLAQSGLTEKSFKSQLKYNLLVQKATEANT
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
DTSDKTLKKYYETWQPDITVSHILVADENKAKEVEQKLKDGAKFADLAKEYSTDTATKDN
CCHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
GGQLAPFGPGKMDPAFEKAAYALKNKGDISAPVKTQYGYHIIQMDKPATKTTFEKDKKAV
CCEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
KASYLESQLTTENMQKTLKKEYKDANVKVEDKDLKDAFKDFDGSSSSESDSSK
HHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA