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The map label for this gene is aroK [H]

Identifier: 226224352

GI number: 226224352

Start: 1805170

End: 1805643

Strand: Direct

Name: aroK [H]

Synonym: Lm4b_01763

Alternate gene names: 226224352

Gene position: 1805170-1805643 (Clockwise)

Preceding gene: 226224338

Following gene: 226224364

Centisome position: 61.98

GC content: 36.71

Gene sequence:

>474_bases
ATGGGAGCTGGAAAAACAACGGTTGGAAATATACTCGCAAACTTAGCTGACTTACCGTACATCGATATTGACGAAGTAAT
TACAAGCGAACAAGGAATGAGTGTATCGGACATTTTTGCTAAATATGGTGAAAAAGAATTCCGCCGTCTAGAACATGAAA
AATTAAAAGAATTAGCAACAACCAAAGCCGTTATAGCAACAGGCGGTGGCATTGTTCTCAATCCTGAAAATAGAGAAGTT
TTAAAAAATACATATCCGGTTATTTATTTAGAAACGGATCCCGAAGTATTTATGAATCGCTTAAAAGGCGACACTACACG
ACCGCTTGTACAACAAAAAACAGCCGAAGAAATTCGCGCTATTTTTGAACCTAGAATTGCTCACTATCAAGATTCTGCAG
ACTTTATCGTTAATACGGATAATCGTAATCAAGAAGAAGTTGCTCGAGCTATTTTAACCATGTTAGATAAGTAA

Upstream 100 bases:

>100_bases
GGCATTTGTGATATAATTTCTTTAATGCTTTTAAGTAGTAAAATGTAATAATCCAATAAAGGAGGAGAACATCATCGATC
AAGTTATCTTAATAGGCTTC

Downstream 100 bases:

>100_bases
AAAAACAACGCTAATTTTAGCGTTGTTTTTTTATTCTGTACAATGTCTGCACCACATATCTGGTAACACAGATGTATAGT
CTTTTGTAAAGGTTAATAAG

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MGAGKTTVGNILANLADLPYIDIDEVITSEQGMSVSDIFAKYGEKEFRRLEHEKLKELATTKAVIATGGGIVLNPENREV
LKNTYPVIYLETDPEVFMNRLKGDTTRPLVQQKTAEEIRAIFEPRIAHYQDSADFIVNTDNRNQEEVARAILTMLDK

Sequences:

>Translated_157_residues
MGAGKTTVGNILANLADLPYIDIDEVITSEQGMSVSDIFAKYGEKEFRRLEHEKLKELATTKAVIATGGGIVLNPENREV
LKNTYPVIYLETDPEVFMNRLKGDTTRPLVQQKTAEEIRAIFEPRIAHYQDSADFIVNTDNRNQEEVARAILTMLDK
>Mature_156_residues
GAGKTTVGNILANLADLPYIDIDEVITSEQGMSVSDIFAKYGEKEFRRLEHEKLKELATTKAVIATGGGIVLNPENREVL
KNTYPVIYLETDPEVFMNRLKGDTTRPLVQQKTAEEIRAIFEPRIAHYQDSADFIVNTDNRNQEEVARAILTMLDK

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=159, Percent_Identity=35.8490566037736, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1786587, Length=144, Percent_Identity=34.7222222222222, Blast_Score=84, Evalue=6e-18,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 17656; Mature: 17525

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAGKTTVGNILANLADLPYIDIDEVITSEQGMSVSDIFAKYGEKEFRRLEHEKLKELAT
CCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHH
TKAVIATGGGIVLNPENREVLKNTYPVIYLETDPEVFMNRLKGDTTRPLVQQKTAEEIRA
HHHHEEECCCEEECCCCHHHHHCCCCEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHH
IFEPRIAHYQDSADFIVNTDNRNQEEVARAILTMLDK
HHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
GAGKTTVGNILANLADLPYIDIDEVITSEQGMSVSDIFAKYGEKEFRRLEHEKLKELAT
CCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHH
TKAVIATGGGIVLNPENREVLKNTYPVIYLETDPEVFMNRLKGDTTRPLVQQKTAEEIRA
HHHHEEECCCEEECCCCHHHHHCCCCEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHH
IFEPRIAHYQDSADFIVNTDNRNQEEVARAILTMLDK
HHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]