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The map label for this gene is yocR [H]

Identifier: 226224364

GI number: 226224364

Start: 1819561

End: 1820916

Strand: Direct

Name: yocR [H]

Synonym: Lm4b_01775

Alternate gene names: 226224364

Gene position: 1819561-1820916 (Clockwise)

Preceding gene: 226224352

Following gene: 226224381

Centisome position: 62.47

GC content: 39.97

Gene sequence:

>1356_bases
ATGCAAGAAAACAGAGAAGAATGGGGCTCAAAAGTCGGGTTTATATTAGCATCCGCTGGGTCCGCAATAGGAATTGGTGC
GATTTGGAAACTGCCTTATGTGGCTGCAACTGCAGGAGGTGGCGCATTTTTCTTATTGTTTTTAGTTTTAACTTTACTAG
TTGTGATGCCACTTTTAATTGCAGAATTTGTGATTGGACGAGGCTCTGGCGGAGATGCTGTTCAAGCTTATAAAACACTC
GCGCCCGGAACAAAGTGGAATTTACTTGGAAAATTAGGCGTTGTAGGCGCAAGTATTTTATTTTCGTTTTATAGCGTAGT
TGGTGGTTGGATTATCACTTACTTAATTAAAACACTTGCTGGCGGGATTGCTGGCGAAAATCAAGCAAGTCTGCTGCATG
ATTTCCAAGTGACGACAGCTAACCCGTGGATATCAGTTGGCGCAACGATTCTCTTTATTTTACTAAATGTCATTGTTATT
AGCCGCGGAGTTGTTAGTGGAATTGAAAAAATGAGTAAGTTTATGATGCCAGCTCTATTTATTTTATTTATTGTTTTAAT
TATCAGGTCCTTAACACTACCTGGTGCGATGGAAGGTGTCGCATTTTTCTTACGTCCAGATTTTAGTCATTTCACAGCGC
AAACGGTTCTTATAACGCTTGGTCAGGCCTTCTTCTCACTCAGTGTGGGGATTTCAGTAATGGTGACCTATAGTTCTTAT
TTAAATCGGTCGACTAGTTTACCGCAGTCTGCCATTTCGGTTTCGCTTATGAATGTGTTTGTGTCGCTTCTTGCGGGATT
GGCCATTTTCCCGGCAGCATTTTCGTTTAATATTACACCAGATGCGGGACCTGGATTGCTATTCGTTATTTTACCTTCGA
TTTTCAATCAAATGCCCTTTGGGATGTTGTTCTTTATTATTTTCTTGATTTTATTCTTATTCGCCGCATTAACCTCTAGT
TTCTCGATGCTTGAAGCAACGGTTGCGCCACTGATGAATGCGGGTGTTAATCGTAAAAAAGCAAGTCTTTGGATGGGGCT
CGTGATTGTCTTGATGGCTATTCCAAGTGCGCTTAGTTTTGGCGTTTGGAGCGATGTTCAGATTTTCGGACTAAGTATTT
TTGATGCTGCCGATTATCTTGTGTCGAATATTATCTTGCCAGTTGGTGCTTTATTTATCGCAATTTTCGTTGGTTACCGA
TTACCTCGTGAATTACTTTTAAAAGAATTTACCACAAGCAGCCATTTTGGAAAAAAAGTGTTTATTCTTTGGCTCTTTCT
TATTAAATATATTGCACCAATCGCGATTATTTTCGTCTTCCTCTCCGCAACTGGTTTAATCGATTTTCTGTTTTAA

Upstream 100 bases:

>100_bases
GTTGCTGTTGGGATAGCTTTTATTTTATGGTATGATGAGGAAAATTTGATTTTATTAAGACTTCTGAGTATTTACATAGA
AAAAAGGAAATGGGGATATT

Downstream 100 bases:

>100_bases
CAAAAAAAGCAATCCGCTAAGTTTTTAGCGAGATTGCTTTTCTTATATTGCCATAAGGACAATGCTTGTTACACAAATCA
AGATTCCACTAAGGCCAATC

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MQENREEWGSKVGFILASAGSAIGIGAIWKLPYVAATAGGGAFFLLFLVLTLLVVMPLLIAEFVIGRGSGGDAVQAYKTL
APGTKWNLLGKLGVVGASILFSFYSVVGGWIITYLIKTLAGGIAGENQASLLHDFQVTTANPWISVGATILFILLNVIVI
SRGVVSGIEKMSKFMMPALFILFIVLIIRSLTLPGAMEGVAFFLRPDFSHFTAQTVLITLGQAFFSLSVGISVMVTYSSY
LNRSTSLPQSAISVSLMNVFVSLLAGLAIFPAAFSFNITPDAGPGLLFVILPSIFNQMPFGMLFFIIFLILFLFAALTSS
FSMLEATVAPLMNAGVNRKKASLWMGLVIVLMAIPSALSFGVWSDVQIFGLSIFDAADYLVSNIILPVGALFIAIFVGYR
LPRELLLKEFTTSSHFGKKVFILWLFLIKYIAPIAIIFVFLSATGLIDFLF

Sequences:

>Translated_451_residues
MQENREEWGSKVGFILASAGSAIGIGAIWKLPYVAATAGGGAFFLLFLVLTLLVVMPLLIAEFVIGRGSGGDAVQAYKTL
APGTKWNLLGKLGVVGASILFSFYSVVGGWIITYLIKTLAGGIAGENQASLLHDFQVTTANPWISVGATILFILLNVIVI
SRGVVSGIEKMSKFMMPALFILFIVLIIRSLTLPGAMEGVAFFLRPDFSHFTAQTVLITLGQAFFSLSVGISVMVTYSSY
LNRSTSLPQSAISVSLMNVFVSLLAGLAIFPAAFSFNITPDAGPGLLFVILPSIFNQMPFGMLFFIIFLILFLFAALTSS
FSMLEATVAPLMNAGVNRKKASLWMGLVIVLMAIPSALSFGVWSDVQIFGLSIFDAADYLVSNIILPVGALFIAIFVGYR
LPRELLLKEFTTSSHFGKKVFILWLFLIKYIAPIAIIFVFLSATGLIDFLF
>Mature_451_residues
MQENREEWGSKVGFILASAGSAIGIGAIWKLPYVAATAGGGAFFLLFLVLTLLVVMPLLIAEFVIGRGSGGDAVQAYKTL
APGTKWNLLGKLGVVGASILFSFYSVVGGWIITYLIKTLAGGIAGENQASLLHDFQVTTANPWISVGATILFILLNVIVI
SRGVVSGIEKMSKFMMPALFILFIVLIIRSLTLPGAMEGVAFFLRPDFSHFTAQTVLITLGQAFFSLSVGISVMVTYSSY
LNRSTSLPQSAISVSLMNVFVSLLAGLAIFPAAFSFNITPDAGPGLLFVILPSIFNQMPFGMLFFIIFLILFLFAALTSS
FSMLEATVAPLMNAGVNRKKASLWMGLVIVLMAIPSALSFGVWSDVQIFGLSIFDAADYLVSNIILPVGALFIAIFVGYR
LPRELLLKEFTTSSHFGKKVFILWLFLIKYIAPIAIIFVFLSATGLIDFLF

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI21361581, Length=388, Percent_Identity=26.5463917525773, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI4507043, Length=380, Percent_Identity=26.3157894736842, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI197276623, Length=379, Percent_Identity=25.5936675461741, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI54607094, Length=379, Percent_Identity=25.5936675461741, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI171184408, Length=441, Percent_Identity=23.5827664399093, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI171184406, Length=441, Percent_Identity=23.5827664399093, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI171184404, Length=441, Percent_Identity=23.5827664399093, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI7657587, Length=488, Percent_Identity=23.7704918032787, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI188528618, Length=405, Percent_Identity=22.962962962963, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI134304856, Length=408, Percent_Identity=25, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI4507041, Length=499, Percent_Identity=23.2464929859719, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI289191351, Length=392, Percent_Identity=25.5102040816327, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4557046, Length=392, Percent_Identity=25.5102040816327, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI289191377, Length=392, Percent_Identity=25.5102040816327, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI51468073, Length=299, Percent_Identity=25.4180602006689, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI92859670, Length=411, Percent_Identity=23.8442822384428, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI194018524, Length=327, Percent_Identity=27.217125382263, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI11181770, Length=299, Percent_Identity=26.0869565217391, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI33354281, Length=303, Percent_Identity=23.1023102310231, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI58219014, Length=303, Percent_Identity=26.0726072607261, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI5032097, Length=386, Percent_Identity=24.3523316062176, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI12408638, Length=278, Percent_Identity=23.3812949640288, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI300360519, Length=204, Percent_Identity=27.4509803921569, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI218563756, Length=378, Percent_Identity=24.6031746031746, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI289191353, Length=198, Percent_Identity=28.7878787878788, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI197276625, Length=152, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI21361693, Length=145, Percent_Identity=25.5172413793103, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI25146584, Length=388, Percent_Identity=22.9381443298969, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17554804, Length=365, Percent_Identity=24.6575342465753, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI133952791, Length=204, Percent_Identity=29.4117647058824, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17555248, Length=164, Percent_Identity=29.8780487804878, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71998244, Length=295, Percent_Identity=26.7796610169492, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534083, Length=445, Percent_Identity=22.9213483146067, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71995588, Length=186, Percent_Identity=24.7311827956989, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17136952, Length=431, Percent_Identity=24.5939675174014, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281364394, Length=431, Percent_Identity=24.5939675174014, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28574704, Length=431, Percent_Identity=24.5939675174014, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI17136950, Length=431, Percent_Identity=24.5939675174014, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28574702, Length=431, Percent_Identity=24.5939675174014, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24762620, Length=414, Percent_Identity=25.3623188405797, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI221329674, Length=505, Percent_Identity=23.1683168316832, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24639514, Length=505, Percent_Identity=23.1683168316832, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45550877, Length=415, Percent_Identity=24.0963855421687, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI45551183, Length=415, Percent_Identity=24.0963855421687, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24582567, Length=485, Percent_Identity=24.3298969072165, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24639516, Length=525, Percent_Identity=22.0952380952381, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI45551088, Length=377, Percent_Identity=25.7294429708223, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24652942, Length=377, Percent_Identity=25.7294429708223, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19921936, Length=364, Percent_Identity=25.2747252747253, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI281365034, Length=511, Percent_Identity=24.6575342465753, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24661428, Length=394, Percent_Identity=25.8883248730964, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281364136, Length=517, Percent_Identity=22.2437137330754, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19921352, Length=517, Percent_Identity=24.1779497098646, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24584353, Length=517, Percent_Identity=24.1779497098646, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI281363702, Length=358, Percent_Identity=24.5810055865922, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281363700, Length=302, Percent_Identity=24.5033112582781, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24654186, Length=163, Percent_Identity=31.9018404907975, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24655079, Length=303, Percent_Identity=24.4224422442244, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24582569, Length=455, Percent_Identity=21.978021978022, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 48640; Mature: 48640

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQENREEWGSKVGFILASAGSAIGIGAIWKLPYVAATAGGGAFFLLFLVLTLLVVMPLLI
CCCCHHHHCHHHHHHEECCCCCCCHHHHHHCCHHHEECCCHHHHHHHHHHHHHHHHHHHH
AEFVIGRGSGGDAVQAYKTLAPGTKWNLLGKLGVVGASILFSFYSVVGGWIITYLIKTLA
HHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGIAGENQASLLHDFQVTTANPWISVGATILFILLNVIVISRGVVSGIEKMSKFMMPALF
CCCCCCCHHHHHHHCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILFIVLIIRSLTLPGAMEGVAFFLRPDFSHFTAQTVLITLGQAFFSLSVGISVMVTYSSY
HHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHH
LNRSTSLPQSAISVSLMNVFVSLLAGLAIFPAAFSFNITPDAGPGLLFVILPSIFNQMPF
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCH
GMLFFIIFLILFLFAALTSSFSMLEATVAPLMNAGVNRKKASLWMGLVIVLMAIPSALSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
GVWSDVQIFGLSIFDAADYLVSNIILPVGALFIAIFVGYRLPRELLLKEFTTSSHFGKKV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHCCHHH
FILWLFLIKYIAPIAIIFVFLSATGLIDFLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQENREEWGSKVGFILASAGSAIGIGAIWKLPYVAATAGGGAFFLLFLVLTLLVVMPLLI
CCCCHHHHCHHHHHHEECCCCCCCHHHHHHCCHHHEECCCHHHHHHHHHHHHHHHHHHHH
AEFVIGRGSGGDAVQAYKTLAPGTKWNLLGKLGVVGASILFSFYSVVGGWIITYLIKTLA
HHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGIAGENQASLLHDFQVTTANPWISVGATILFILLNVIVISRGVVSGIEKMSKFMMPALF
CCCCCCCHHHHHHHCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILFIVLIIRSLTLPGAMEGVAFFLRPDFSHFTAQTVLITLGQAFFSLSVGISVMVTYSSY
HHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHH
LNRSTSLPQSAISVSLMNVFVSLLAGLAIFPAAFSFNITPDAGPGLLFVILPSIFNQMPF
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCH
GMLFFIIFLILFLFAALTSSFSMLEATVAPLMNAGVNRKKASLWMGLVIVLMAIPSALSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
GVWSDVQIFGLSIFDAADYLVSNIILPVGALFIAIFVGYRLPRELLLKEFTTSSHFGKKV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHCCHHH
FILWLFLIKYIAPIAIIFVFLSATGLIDFLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]