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The map label for this gene is sftA [H]

Identifier: 226224207

GI number: 226224207

Start: 1633856

End: 1636207

Strand: Reverse

Name: sftA [H]

Synonym: Lm4b_01617

Alternate gene names: 226224207

Gene position: 1636207-1633856 (Counterclockwise)

Preceding gene: 226224208

Following gene: 226224206

Centisome position: 56.18

GC content: 39.75

Gene sequence:

>2352_bases
ATGGGATGGTTTAAAGATTTTTTCTTTGGCGATATGGATGAGGAAATAGATACATACGAAGATACGTCTTCACGAAAAGT
AGAAAAGAAAGCAAAACAACGAGCACCAGAAGTAGTGCAAAAATCAAATGTAACAGCAATTAAAACGAAAGAACGTACTA
TAAGGAACGAACGACCAGTTGCTTACAAAGCAGCTCCGAAACAAAAACATATGCAACCAGTGAAACGACAAATGAAAACG
CAAATGGTATACCAGTATCCAAAAGGCGAATTTCGTTTTCCGTTAATTCCAGATAAACAAAAAAGCCAACCAATTCAACC
AAAAAAACAACCAATAACAAAAAGACAAGCGGCAGAAACGCAACCAGTAAAAGAGGAAACAAGAAAACGACCTTTTACAG
CGACGGATGTACCTTCGCCTGTTTATGCCTTTAATAAACGACCAAGTAAATTTGAGTTTGCTGTAACAGAAGCAGAAGAA
CTTAGTACAATACAAGAAGATTTAACTATTACTCCAGTAGATTTATTAGATTCAGCAGAAGCGGAAACAATTGCTTTTGA
CACAGAGCTAAATCGTCAAATAGAAGAAGAGATTGTGTCAGTGCCAGTGACGGAAGAAGTCATTACGGAGCAACCAGAAG
TGAAAGTAACCCCAGAACCAGTAGAACAGCAAGAACCAGCACGCGTTTCCCTTATAACGGAAGAGCCGGCGCAAACGAAA
ACAACTACTAGAAGCAAACAAGTAGAATCAAATAGACAAGAACAATTGCTAAAAAGCAGAATTCCATTTAATGTCATGAT
GGTAAAGAAAGACAAACAAGCACTTCGAAAAGAAGAAGCACAGGAAATAAATGGGCAACAACCAGTTGAGGTAGAAGCAG
AACAAACGAATACTGTTCGAGAAGCGCAAGTAGCGACAGTCTCTTACCCAACGAACTATGAATTTCCGTCGTTTAGTTTG
CTCCATCCGCCAGTCTCCAAACGAGAAGACGACTCATGGCTACAAATGCAGCAAGAGATGCTAGATGAAACCTTGGAAAA
TTTCAACGTACAAGCTAGTGTAGTTAACCGTACACAAGGTCCAGCAGTAACTAGATTTGAAGTGCAACCTGAAAAAGGCG
TTAAAGTTAGCAAAATCACTAATTTAACGGATGATATTAAATTAAATTTAGCAGCGAAAGATATACGGATTGAGGCGCCG
ATACCTGGTAAGAGTACAGTAGGGATAGAAATTCCGAATCAGACAAGTCGTCCCGTAATGCTTTCTGAATTGATGAATAC
GGAAGCTTTTCAGTCATCTACATCACCGCTCACAGCGGCACTCGGGCTAGATATCTCGGGAACGCCAATTATTACTGATT
TACAAAAAATGCCCCACGGTTTAATCGCTGGAGCTACAGGGTCAGGGAAAAGTGTTTGTATCAATTCATTGCTAGTAAGT
TTACTTTACAAAGCAACGCCAGACCAATTGAAACTACTTTTGATTGACCCTAAGATGGTCGAATTAGCTCCGTACAACCG
GATACCACATCTTGTGAGTCCAGTTATTACGGATGCCAAAGCAGCTACTGTCGCTTTAAAATGGGCGGTAGAAGAAATGG
AACGTCGCTATCAATTATTTAGCCATACAGGCGTTAGGAATATGGAAAAATATAATGAATACGCTAGTCACCCAGATCAT
ACAGGGGAGAAATTACCTTATATTTTAATTGTGATTGATGAATTAGCTGATTTGATGATGGTTGCGCCAAATGATGTAGA
AGAATCCATTAGCCGCATCGCACAAAAAGCAAGAGCTTGTGGCATTCATATGATTGTAGCGACACAGCGCCCATCTGTAG
ACGTTATTACAGGTCTCATTAAGGCGAATATCCCTACACGTGTTTCGTTCTCTGTATCTTCTCAAATCGACTCTAGAACG
ATTTTAGATGCAAGCGGAGCAGAAAAATTACTCGGAAAAGGGGACATGCTCTTCTTACCAAGTGGTGCAAGTAAGCCAGT
GCGTTTACAAGGAACCTTCGTTAGTGATGAAGAGATTGATGCAGTTGTTGCTCATGTTCGGAGTCAAGGCGAGGCCGATT
ATATCTTTGAAGAACAAGAATTACTTGTAAAAGAAACGGCAAAAGAAAATACCGATGAATTATTTGAAGAAGCGTGTGAC
TTTGTTTTAAGCCAAAATGCTGCCTCAACATCCTTGTTGCAAAGACATTTTAGAATTGGTTATAACCGAGCGGCGAGATT
AATGGAATCCCTTGAAAATCATCAAATTGTTTCTGGGATAAATGGTTCCAAACCGCGAGATGTTATTATTACAAAGGACC
AATTAGCTAAGTTGCGAAACAAAGAATCTTAA

Upstream 100 bases:

>100_bases
AATATGGCTCGAAAAAAGGCGAATTCACAATTTTGTCATAGATTATTTTGTTTTTGTCTGTTAAAATCAAACAAGAAAAT
TAAATTTAGGGTGATAATGA

Downstream 100 bases:

>100_bases
TTTTGTAGTACTAAACTAACATATTACTTAATTAGTTTTACAAATAATGGCTATTTTCATGAGTAATTTCGCTTATATTC
GCTGAAAGATTTTTCTATTT

Product: cell division protein (DNA translocase) dnaK

Products: NA

Alternate protein names: Septum-associated ftsK-like translocase of DNA [H]

Number of amino acids: Translated: 783; Mature: 782

Protein sequence:

>783_residues
MGWFKDFFFGDMDEEIDTYEDTSSRKVEKKAKQRAPEVVQKSNVTAIKTKERTIRNERPVAYKAAPKQKHMQPVKRQMKT
QMVYQYPKGEFRFPLIPDKQKSQPIQPKKQPITKRQAAETQPVKEETRKRPFTATDVPSPVYAFNKRPSKFEFAVTEAEE
LSTIQEDLTITPVDLLDSAEAETIAFDTELNRQIEEEIVSVPVTEEVITEQPEVKVTPEPVEQQEPARVSLITEEPAQTK
TTTRSKQVESNRQEQLLKSRIPFNVMMVKKDKQALRKEEAQEINGQQPVEVEAEQTNTVREAQVATVSYPTNYEFPSFSL
LHPPVSKREDDSWLQMQQEMLDETLENFNVQASVVNRTQGPAVTRFEVQPEKGVKVSKITNLTDDIKLNLAAKDIRIEAP
IPGKSTVGIEIPNQTSRPVMLSELMNTEAFQSSTSPLTAALGLDISGTPIITDLQKMPHGLIAGATGSGKSVCINSLLVS
LLYKATPDQLKLLLIDPKMVELAPYNRIPHLVSPVITDAKAATVALKWAVEEMERRYQLFSHTGVRNMEKYNEYASHPDH
TGEKLPYILIVIDELADLMMVAPNDVEESISRIAQKARACGIHMIVATQRPSVDVITGLIKANIPTRVSFSVSSQIDSRT
ILDASGAEKLLGKGDMLFLPSGASKPVRLQGTFVSDEEIDAVVAHVRSQGEADYIFEEQELLVKETAKENTDELFEEACD
FVLSQNAASTSLLQRHFRIGYNRAARLMESLENHQIVSGINGSKPRDVIITKDQLAKLRNKES

Sequences:

>Translated_783_residues
MGWFKDFFFGDMDEEIDTYEDTSSRKVEKKAKQRAPEVVQKSNVTAIKTKERTIRNERPVAYKAAPKQKHMQPVKRQMKT
QMVYQYPKGEFRFPLIPDKQKSQPIQPKKQPITKRQAAETQPVKEETRKRPFTATDVPSPVYAFNKRPSKFEFAVTEAEE
LSTIQEDLTITPVDLLDSAEAETIAFDTELNRQIEEEIVSVPVTEEVITEQPEVKVTPEPVEQQEPARVSLITEEPAQTK
TTTRSKQVESNRQEQLLKSRIPFNVMMVKKDKQALRKEEAQEINGQQPVEVEAEQTNTVREAQVATVSYPTNYEFPSFSL
LHPPVSKREDDSWLQMQQEMLDETLENFNVQASVVNRTQGPAVTRFEVQPEKGVKVSKITNLTDDIKLNLAAKDIRIEAP
IPGKSTVGIEIPNQTSRPVMLSELMNTEAFQSSTSPLTAALGLDISGTPIITDLQKMPHGLIAGATGSGKSVCINSLLVS
LLYKATPDQLKLLLIDPKMVELAPYNRIPHLVSPVITDAKAATVALKWAVEEMERRYQLFSHTGVRNMEKYNEYASHPDH
TGEKLPYILIVIDELADLMMVAPNDVEESISRIAQKARACGIHMIVATQRPSVDVITGLIKANIPTRVSFSVSSQIDSRT
ILDASGAEKLLGKGDMLFLPSGASKPVRLQGTFVSDEEIDAVVAHVRSQGEADYIFEEQELLVKETAKENTDELFEEACD
FVLSQNAASTSLLQRHFRIGYNRAARLMESLENHQIVSGINGSKPRDVIITKDQLAKLRNKES
>Mature_782_residues
GWFKDFFFGDMDEEIDTYEDTSSRKVEKKAKQRAPEVVQKSNVTAIKTKERTIRNERPVAYKAAPKQKHMQPVKRQMKTQ
MVYQYPKGEFRFPLIPDKQKSQPIQPKKQPITKRQAAETQPVKEETRKRPFTATDVPSPVYAFNKRPSKFEFAVTEAEEL
STIQEDLTITPVDLLDSAEAETIAFDTELNRQIEEEIVSVPVTEEVITEQPEVKVTPEPVEQQEPARVSLITEEPAQTKT
TTRSKQVESNRQEQLLKSRIPFNVMMVKKDKQALRKEEAQEINGQQPVEVEAEQTNTVREAQVATVSYPTNYEFPSFSLL
HPPVSKREDDSWLQMQQEMLDETLENFNVQASVVNRTQGPAVTRFEVQPEKGVKVSKITNLTDDIKLNLAAKDIRIEAPI
PGKSTVGIEIPNQTSRPVMLSELMNTEAFQSSTSPLTAALGLDISGTPIITDLQKMPHGLIAGATGSGKSVCINSLLVSL
LYKATPDQLKLLLIDPKMVELAPYNRIPHLVSPVITDAKAATVALKWAVEEMERRYQLFSHTGVRNMEKYNEYASHPDHT
GEKLPYILIVIDELADLMMVAPNDVEESISRIAQKARACGIHMIVATQRPSVDVITGLIKANIPTRVSFSVSSQIDSRTI
LDASGAEKLLGKGDMLFLPSGASKPVRLQGTFVSDEEIDAVVAHVRSQGEADYIFEEQELLVKETAKENTDELFEEACDF
VLSQNAASTSLLQRHFRIGYNRAARLMESLENHQIVSGINGSKPRDVIITKDQLAKLRNKES

Specific function: Required for the accurate completion of chromosome partitioning, in part by promoting efficient resolution of chromosome dimers, before the formation of the division septum. Binds to DNA in a non-specific manner. Shows ATPase activity. Not required for cy

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cytoplasm. Note=Colocalizes with ftsZ at nascent division sites [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=481, Percent_Identity=46.985446985447, Blast_Score=440, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 87866; Mature: 87735

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGWFKDFFFGDMDEEIDTYEDTSSRKVEKKAKQRAPEVVQKSNVTAIKTKERTIRNERPV
CCCHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHCHHHHHHCCCEEEECHHHHHCCCCCE
AYKAAPKQKHMQPVKRQMKTQMVYQYPKGEFRFPLIPDKQKSQPIQPKKQPITKRQAAET
EEECCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHCC
QPVKEETRKRPFTATDVPSPVYAFNKRPSKFEFAVTEAEELSTIQEDLTITPVDLLDSAE
CCHHHHHHCCCCCCCCCCCCHHHHCCCCCCEEEEECCHHHHHHHHHCCEECCHHHHCCCC
AETIAFDTELNRQIEEEIVSVPVTEEVITEQPEVKVTPEPVEQQEPARVSLITEEPAQTK
CCEEEECHHHHHHHHHHHHCCCCCHHHHCCCCCEEECCCCCCCCCCCEEEEEECCCCCCH
TTTRSKQVESNRQEQLLKSRIPFNVMMVKKDKQALRKEEAQEINGQQPVEVEAEQTNTVR
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHCCCCCCEEEEHHHCCCHH
EAQVATVSYPTNYEFPSFSLLHPPVSKREDDSWLQMQQEMLDETLENFNVQASVVNRTQG
HHEEEEEECCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
PAVTRFEVQPEKGVKVSKITNLTDDIKLNLAAKDIRIEAPIPGKSTVGIEIPNQTSRPVM
CCEEEEEECCCCCCCHHHHCCCCCCEEEEEEEEEEEEECCCCCCCEEEEECCCCCCCCHH
LSELMNTEAFQSSTSPLTAALGLDISGTPIITDLQKMPHGLIAGATGSGKSVCINSLLVS
HHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHH
LLYKATPDQLKLLLIDPKMVELAPYNRIPHLVSPVITDAKAATVALKWAVEEMERRYQLF
HHHHCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SHTGVRNMEKYNEYASHPDHTGEKLPYILIVIDELADLMMVAPNDVEESISRIAQKARAC
HHCCHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHEEECCCCHHHHHHHHHHHHHHC
GIHMIVATQRPSVDVITGLIKANIPTRVSFSVSSQIDSRTILDASGAEKLLGKGDMLFLP
CEEEEEEECCCCHHHHHHHHHCCCCCEEEEEHHCCCCCCEEECCCCHHHHHCCCCEEEEC
SGASKPVRLQGTFVSDEEIDAVVAHVRSQGEADYIFEEQELLVKETAKENTDELFEEACD
CCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHCCCHHHHHHHHHH
FVLSQNAASTSLLQRHFRIGYNRAARLMESLENHQIVSGINGSKPRDVIITKDQLAKLRN
HHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEHHHHHHHHC
KES
CCC
>Mature Secondary Structure 
GWFKDFFFGDMDEEIDTYEDTSSRKVEKKAKQRAPEVVQKSNVTAIKTKERTIRNERPV
CCHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHCHHHHHHCCCEEEECHHHHHCCCCCE
AYKAAPKQKHMQPVKRQMKTQMVYQYPKGEFRFPLIPDKQKSQPIQPKKQPITKRQAAET
EEECCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHCC
QPVKEETRKRPFTATDVPSPVYAFNKRPSKFEFAVTEAEELSTIQEDLTITPVDLLDSAE
CCHHHHHHCCCCCCCCCCCCHHHHCCCCCCEEEEECCHHHHHHHHHCCEECCHHHHCCCC
AETIAFDTELNRQIEEEIVSVPVTEEVITEQPEVKVTPEPVEQQEPARVSLITEEPAQTK
CCEEEECHHHHHHHHHHHHCCCCCHHHHCCCCCEEECCCCCCCCCCCEEEEEECCCCCCH
TTTRSKQVESNRQEQLLKSRIPFNVMMVKKDKQALRKEEAQEINGQQPVEVEAEQTNTVR
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHCCCCCCEEEEHHHCCCHH
EAQVATVSYPTNYEFPSFSLLHPPVSKREDDSWLQMQQEMLDETLENFNVQASVVNRTQG
HHEEEEEECCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
PAVTRFEVQPEKGVKVSKITNLTDDIKLNLAAKDIRIEAPIPGKSTVGIEIPNQTSRPVM
CCEEEEEECCCCCCCHHHHCCCCCCEEEEEEEEEEEEECCCCCCCEEEEECCCCCCCCHH
LSELMNTEAFQSSTSPLTAALGLDISGTPIITDLQKMPHGLIAGATGSGKSVCINSLLVS
HHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHH
LLYKATPDQLKLLLIDPKMVELAPYNRIPHLVSPVITDAKAATVALKWAVEEMERRYQLF
HHHHCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SHTGVRNMEKYNEYASHPDHTGEKLPYILIVIDELADLMMVAPNDVEESISRIAQKARAC
HHCCHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHEEECCCCHHHHHHHHHHHHHHC
GIHMIVATQRPSVDVITGLIKANIPTRVSFSVSSQIDSRTILDASGAEKLLGKGDMLFLP
CEEEEEEECCCCHHHHHHHHHCCCCCEEEEEHHCCCCCCEEECCCCHHHHHCCCCEEEEC
SGASKPVRLQGTFVSDEEIDAVVAHVRSQGEADYIFEEQELLVKETAKENTDELFEEACD
CCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHCCCHHHHHHHHHH
FVLSQNAASTSLLQRHFRIGYNRAARLMESLENHQIVSGINGSKPRDVIITKDQLAKLRN
HHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEHHHHHHHHC
KES
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]