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The map label for this gene is aroA

Identifier: 226224201

GI number: 226224201

Start: 1627813

End: 1628898

Strand: Reverse

Name: aroA

Synonym: Lm4b_01611

Alternate gene names: 226224201

Gene position: 1628898-1627813 (Counterclockwise)

Preceding gene: 226224202

Following gene: 226224200

Centisome position: 55.92

GC content: 36.83

Gene sequence:

>1086_bases
ATGGTTAATACAAATTTAGAGGAACTTAGAACACAGGTGGATCAATTAAATATTGATTTGCTAGAATTAATTAGCAAACG
CGCTAATTTGGTACAAGAAATTGGCAAAATTAAAGGAACTCAAGGTTCTCTTCGTTTTGATCCATTACGTGAAAGAGAAA
TGCTTAACACGATTCTTGCAGCAAATGAAGGACCTTTTGAAGATAGTACGGTTCAAAAATTATTTAAAGAAATTTTTAAA
GCGGGATTAGAGCTTCAAGAAGAAGATCACTCTAAAGCATTACTCGTTTCTAGAAAAAACAAAAAAGAAGATACGATAGT
TACAGTAAAAGGATTGCCAATCGGGAATGGCGAACCAGTATTTGTTTTCGGTCCATGTTCAGTGGAATCTTATGAACAGG
TTGCTGCGGTCGCTGAATCCATTAAAGCGAAAGGCTTAAAACTTATTCGTGGCGGCGCATTTAAACCTCGTACTAGCCCA
TATGACTTCCAAGGATTAGGTTTAGAAGGACTGAAAATTTTAAAACGTGTATCTGATGAATACGGTTTAGGTGTTATTAG
TGAAATCGTTACGCCGGCTGATATTGAAGTTGCACTTGATTATGTAGATGTTATTCAAATTGGTGCAAGAAACATGCAAA
ACTTCGAATTACTAAAAGCGGCTGGCCGTGTGGACAAACCCATTTTACTAAAACGTGGTTTATCTGCTACAATCGAAGAA
TTCATTGGTGCTGCTGAATATATCATGTCACAAGGAAATGGCAAAATCATCTTATGCGAACGAGGTATCCGCACATATGA
AAAAGCGACAAGAAATACACTTGATATTTCTGCCGTTCCAATTTTGAAAAAAGAAACTCATTTACCAGTTATGGTTGATG
TGACGCATTCTACTGGTCGAAAAGATTTATTACTTCCATGCGCAAAAGCTGCTCTAGCTATCGAGGCAGATGGCGTGATG
GCTGAAGTTCATCCAGATCCTGCAGTTGCATTATCGGATTCTGCACAACAAATGGATATTCCTGAATTTGAAGAATTCTG
GAATGCAATTTTAGCAAGTAATTTAGTACCACATAAAATAAAGTAA

Upstream 100 bases:

>100_bases
AAAAGCGATTAAGTATAAAAGTGGATTCGTGACAAATTATCTGTTTTCCTCTATAATGAGAAATAATCTTGGAGCAGATT
TTTAGAAGGGTGGAAGTTAA

Downstream 100 bases:

>100_bases
CATCAAAAAACCTTGGGATTCCAAGGTTTTTTGTTTTGCTATTAACAACTCATATTCTATCGGCATTTAATTTTGTGTAA
TAATGCCGTTTTGATATGAA

Product: bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase

Products: NA

Alternate protein names: Phospho-2-dehydro-3-deoxyheptonate aldolase; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase; Chorismate mutase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MVNTNLEELRTQVDQLNIDLLELISKRANLVQEIGKIKGTQGSLRFDPLREREMLNTILAANEGPFEDSTVQKLFKEIFK
AGLELQEEDHSKALLVSRKNKKEDTIVTVKGLPIGNGEPVFVFGPCSVESYEQVAAVAESIKAKGLKLIRGGAFKPRTSP
YDFQGLGLEGLKILKRVSDEYGLGVISEIVTPADIEVALDYVDVIQIGARNMQNFELLKAAGRVDKPILLKRGLSATIEE
FIGAAEYIMSQGNGKIILCERGIRTYEKATRNTLDISAVPILKKETHLPVMVDVTHSTGRKDLLLPCAKAALAIEADGVM
AEVHPDPAVALSDSAQQMDIPEFEEFWNAILASNLVPHKIK

Sequences:

>Translated_361_residues
MVNTNLEELRTQVDQLNIDLLELISKRANLVQEIGKIKGTQGSLRFDPLREREMLNTILAANEGPFEDSTVQKLFKEIFK
AGLELQEEDHSKALLVSRKNKKEDTIVTVKGLPIGNGEPVFVFGPCSVESYEQVAAVAESIKAKGLKLIRGGAFKPRTSP
YDFQGLGLEGLKILKRVSDEYGLGVISEIVTPADIEVALDYVDVIQIGARNMQNFELLKAAGRVDKPILLKRGLSATIEE
FIGAAEYIMSQGNGKIILCERGIRTYEKATRNTLDISAVPILKKETHLPVMVDVTHSTGRKDLLLPCAKAALAIEADGVM
AEVHPDPAVALSDSAQQMDIPEFEEFWNAILASNLVPHKIK
>Mature_361_residues
MVNTNLEELRTQVDQLNIDLLELISKRANLVQEIGKIKGTQGSLRFDPLREREMLNTILAANEGPFEDSTVQKLFKEIFK
AGLELQEEDHSKALLVSRKNKKEDTIVTVKGLPIGNGEPVFVFGPCSVESYEQVAAVAESIKAKGLKLIRGGAFKPRTSP
YDFQGLGLEGLKILKRVSDEYGLGVISEIVTPADIEVALDYVDVIQIGARNMQNFELLKAAGRVDKPILLKRGLSATIEE
FIGAAEYIMSQGNGKIILCERGIRTYEKATRNTLDISAVPILKKETHLPVMVDVTHSTGRKDLLLPCAKAALAIEADGVM
AEVHPDPAVALSDSAQQMDIPEFEEFWNAILASNLVPHKIK

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 chorismate mutase domain [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=268, Percent_Identity=27.2388059701493, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002701
- InterPro:   IPR010954
- InterPro:   IPR020822
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF01817 CM_2; PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54; =5.4.99.5 [H]

Molecular weight: Translated: 39685; Mature: 39685

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNTNLEELRTQVDQLNIDLLELISKRANLVQEIGKIKGTQGSLRFDPLREREMLNTILA
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
ANEGPFEDSTVQKLFKEIFKAGLELQEEDHSKALLVSRKNKKEDTIVTVKGLPIGNGEPV
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEEEECEECCCCCEE
FVFGPCSVESYEQVAAVAESIKAKGLKLIRGGAFKPRTSPYDFQGLGLEGLKILKRVSDE
EEEECCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YGLGVISEIVTPADIEVALDYVDVIQIGARNMQNFELLKAAGRVDKPILLKRGLSATIEE
CCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHH
FIGAAEYIMSQGNGKIILCERGIRTYEKATRNTLDISAVPILKKETHLPVMVDVTHSTGR
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCEEEEEEEECCCCCCEEEEECCCCCC
KDLLLPCAKAALAIEADGVMAEVHPDPAVALSDSAQQMDIPEFEEFWNAILASNLVPHKI
CCHHHHHHHHHEEEECCCEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCC
K
C
>Mature Secondary Structure
MVNTNLEELRTQVDQLNIDLLELISKRANLVQEIGKIKGTQGSLRFDPLREREMLNTILA
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
ANEGPFEDSTVQKLFKEIFKAGLELQEEDHSKALLVSRKNKKEDTIVTVKGLPIGNGEPV
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEEEECEECCCCCEE
FVFGPCSVESYEQVAAVAESIKAKGLKLIRGGAFKPRTSPYDFQGLGLEGLKILKRVSDE
EEEECCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YGLGVISEIVTPADIEVALDYVDVIQIGARNMQNFELLKAAGRVDKPILLKRGLSATIEE
CCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHH
FIGAAEYIMSQGNGKIILCERGIRTYEKATRNTLDISAVPILKKETHLPVMVDVTHSTGR
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCEEEEEEEECCCCCCEEEEECCCCCC
KDLLLPCAKAALAIEADGVMAEVHPDPAVALSDSAQQMDIPEFEEFWNAILASNLVPHKI
CCHHHHHHHHHEEEECCCEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7496534; 9387221; 9384377 [H]