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The map label for this gene is udk

Identifier: 226224098

GI number: 226224098

Start: 1511800

End: 1512429

Strand: Reverse

Name: udk

Synonym: Lm4b_01507

Alternate gene names: 226224098

Gene position: 1512429-1511800 (Counterclockwise)

Preceding gene: 226224099

Following gene: 226224097

Centisome position: 51.93

GC content: 34.6

Gene sequence:

>630_bases
ATGACAAAAAAACCAATCGTAGTCGGCGTAACTGGCGGTTCAGGTTCTGGTAAAACTAGTGTAACGAAAGCCATTTGTGA
TCATTTTAGCGGACACTCGATTTTGATGATTGCTCAAGATGTCTATTATCACGATCAAGCCAATATTAGTTTTGAAGATA
GATTAAAAGTAAATTATGATCATCCACTAGCTTTTGATACGGACTTACTCATTTCACATATTGCCGCACTGCGTCGCTAT
GAAACCATAGAAAAGCCGATTTATGATTATGCCAAATATACGCGAAAAAAAGAAGTAGAAATCCAAGAACCTAGAGAAGT
TATTATTTTAGAAGGAATTTTAATTTTAGAAGATAAACGCCTTAGGGATTTGATGGATATTAAAGTATATGTGGATACCG
ATGATGATATTCGTTTTATTCGCAGACTTTTACGCGATATGAAAGAACGTGGTCGGACAATGGATTCTGTTATCGAGCAA
TATCTTTCTGTTGTTAAACCAATGCACAATGAATTTATAGAACCAACGAAAAAATTTGCCGATATTATTATTCCAGAAGG
CGGAGAGAATCACGTTGCAATCGACTTAATGACAACAAAAATTGAATCCATTTTGCAAAAACATGTATAA

Upstream 100 bases:

>100_bases
TTAACGATTTTTTAGTGACGCATCCTGATTTTGAAACAACGACCATTCCACTAGGGGACGGCCTATCTATTTCCAAAAGA
AAGAAAACTGGAGGCGTATC

Downstream 100 bases:

>100_bases
ACAACAGGTATCACTTGTCAAATAGAGAAATTTAAGGTAAAATTTTTCTAGTAAAAAGAGTGGCAATTGCTTGCTATTTC
TAACGTGGCGTGTTAATCTT

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MTKKPIVVGVTGGSGSGKTSVTKAICDHFSGHSILMIAQDVYYHDQANISFEDRLKVNYDHPLAFDTDLLISHIAALRRY
ETIEKPIYDYAKYTRKKEVEIQEPREVIILEGILILEDKRLRDLMDIKVYVDTDDDIRFIRRLLRDMKERGRTMDSVIEQ
YLSVVKPMHNEFIEPTKKFADIIIPEGGENHVAIDLMTTKIESILQKHV

Sequences:

>Translated_209_residues
MTKKPIVVGVTGGSGSGKTSVTKAICDHFSGHSILMIAQDVYYHDQANISFEDRLKVNYDHPLAFDTDLLISHIAALRRY
ETIEKPIYDYAKYTRKKEVEIQEPREVIILEGILILEDKRLRDLMDIKVYVDTDDDIRFIRRLLRDMKERGRTMDSVIEQ
YLSVVKPMHNEFIEPTKKFADIIIPEGGENHVAIDLMTTKIESILQKHV
>Mature_208_residues
TKKPIVVGVTGGSGSGKTSVTKAICDHFSGHSILMIAQDVYYHDQANISFEDRLKVNYDHPLAFDTDLLISHIAALRRYE
TIEKPIYDYAKYTRKKEVEIQEPREVIILEGILILEDKRLRDLMDIKVYVDTDDDIRFIRRLLRDMKERGRTMDSVIEQY
LSVVKPMHNEFIEPTKKFADIIIPEGGENHVAIDLMTTKIESILQKHV

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI301129207, Length=211, Percent_Identity=39.8104265402844, Blast_Score=170, Evalue=7e-43,
Organism=Homo sapiens, GI57863312, Length=211, Percent_Identity=39.8104265402844, Blast_Score=170, Evalue=8e-43,
Organism=Homo sapiens, GI18699734, Length=211, Percent_Identity=38.3886255924171, Blast_Score=167, Evalue=7e-42,
Organism=Homo sapiens, GI13899253, Length=216, Percent_Identity=36.1111111111111, Blast_Score=155, Evalue=3e-38,
Organism=Homo sapiens, GI209863022, Length=152, Percent_Identity=30.9210526315789, Blast_Score=95, Evalue=4e-20,
Organism=Escherichia coli, GI87082034, Length=209, Percent_Identity=44.9760765550239, Blast_Score=202, Evalue=9e-54,
Organism=Caenorhabditis elegans, GI17539894, Length=207, Percent_Identity=39.1304347826087, Blast_Score=166, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI17539892, Length=207, Percent_Identity=39.1304347826087, Blast_Score=166, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI71981181, Length=220, Percent_Identity=33.6363636363636, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6324339, Length=195, Percent_Identity=35.3846153846154, Blast_Score=114, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320223, Length=198, Percent_Identity=24.2424242424242, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28573516, Length=210, Percent_Identity=38.5714285714286, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28573514, Length=210, Percent_Identity=38.5714285714286, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28573512, Length=210, Percent_Identity=38.5714285714286, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI45550449, Length=210, Percent_Identity=38.5714285714286, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24649624, Length=213, Percent_Identity=39.4366197183099, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI221458995, Length=215, Percent_Identity=38.6046511627907, Blast_Score=159, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 24148; Mature: 24017

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKPIVVGVTGGSGSGKTSVTKAICDHFSGHSILMIAQDVYYHDQANISFEDRLKVNYD
CCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEEEHEECCCCCCCHHHCEEECCC
HPLAFDTDLLISHIAALRRYETIEKPIYDYAKYTRKKEVEIQEPREVIILEGILILEDKR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECEEEECCHH
LRDLMDIKVYVDTDDDIRFIRRLLRDMKERGRTMDSVIEQYLSVVKPMHNEFIEPTKKFA
HHHHEEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIIIPEGGENHVAIDLMTTKIESILQKHV
HEECCCCCCCEEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKKPIVVGVTGGSGSGKTSVTKAICDHFSGHSILMIAQDVYYHDQANISFEDRLKVNYD
CCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEEEHEECCCCCCCHHHCEEECCC
HPLAFDTDLLISHIAALRRYETIEKPIYDYAKYTRKKEVEIQEPREVIILEGILILEDKR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECEEEECCHH
LRDLMDIKVYVDTDDDIRFIRRLLRDMKERGRTMDSVIEQYLSVVKPMHNEFIEPTKKFA
HHHHEEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIIIPEGGENHVAIDLMTTKIESILQKHV
HEECCCCCCCEEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]