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The map label for this gene is yqhT [H]

Identifier: 226223955

GI number: 226223955

Start: 1362534

End: 1363595

Strand: Direct

Name: yqhT [H]

Synonym: Lm4b_01362

Alternate gene names: 226223955

Gene position: 1362534-1363595 (Clockwise)

Preceding gene: 226223951

Following gene: 226223956

Centisome position: 46.78

GC content: 36.63

Gene sequence:

>1062_bases
ATGTCTAAATTAACTAAAATTCAAGAAACGCTGGGCAAGGAAAAGATAGAAGCCGTTCTTGTCACAAGTGAGTTTAATAG
AAGGTATGTATCAGGTTTCACTGGAACAAGTGGTGTGGCGCTAATTTTACCTGAAAAAGCTTATTTTGTAACTGATTTCA
GATATACGGAACAAGCAGCAAAACAAGCAGAAGGATACGAAATTGTACAACATACTGGTCCGATTTTTGATACAGTAGAA
GATTTATTAATTAAAAATGATACAAAAACACTACATTTTGAAGCGGATTATGTGACCGTATCTGAATTTAAACAAATGGA
GCGCGTATTTAATCGTCAATTAATCCCACTTACTGGCTTCTTTGAAGAAATGCGTAAAGTGAAAACAGCAAGTGAACTAA
AAGCAATCCGCACAGCTTGTGATATTGCTGATGCAGCTTTTGCACATATCATTCAATTTATCAAACCAGGCATGGCTGAA
ATCGAAGTATCTAATGAACTAGAATTCTTTATGAGACGTGCGGGAGCTACTTCCTCGTCGTTTGATACAATTGTCGCATC
TGGTGTTCGTTCTGCGTTACCGCATGGTGTTGCTTCGGATAAAAAAATCGAAGTTGGCGATTTCGTTACAATGGATTACG
GCTGTTACTATGACGGTTATTGTTCAGATATGACAAGAACTATCGCGGTCGGTGAACCTGCTGAAAAATTAAAAGAAATT
TACCAAATTACGTTAGATGCGCAATTAAAAGTAATCGATAGCTTAAAACCAGGTATGACTGGAATTGAAGCAGATGCTAT
TGCACGTGATTATATTGCTTCTTTTGGCTATGGCGATGCATTTGGACATTCTTTAGGACATGGTATTGGACTAGAAATTC
ACGAAGGACCTAATTTATCCTTTAAGAGCCCTCAAAAACTAGAAGTCGGACATGTTGTGACGGATGAACCAGGAATTTAT
TTACCAGGAATCGGTGGCGTTAGAATTGAAGATGATCTCTTAATTACAGAAACAGGTAATGAGATTTTAATTCATTCACC
AAAAGAATTAATTATTTTATAA

Upstream 100 bases:

>100_bases
AAAAAAGTTATTTTTTCTAAATTGTGATAAAATAGTTTCGAACGCGTCTAATAATGCGATTTTTGCGCGCCTAAAATTTG
ATAAAAGTGGGGGAATAAAA

Downstream 100 bases:

>100_bases
AATTCCTTTGTAACTTTGTGTGTTTTATGGTTAAATAAGGAAGAATGAGCAGTTTTAATATGCTCCAAATAAAGATACTT
TGCAAATTACAGGAGGAAAA

Product: aminopeptidase P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSKLTKIQETLGKEKIEAVLVTSEFNRRYVSGFTGTSGVALILPEKAYFVTDFRYTEQAAKQAEGYEIVQHTGPIFDTVE
DLLIKNDTKTLHFEADYVTVSEFKQMERVFNRQLIPLTGFFEEMRKVKTASELKAIRTACDIADAAFAHIIQFIKPGMAE
IEVSNELEFFMRRAGATSSSFDTIVASGVRSALPHGVASDKKIEVGDFVTMDYGCYYDGYCSDMTRTIAVGEPAEKLKEI
YQITLDAQLKVIDSLKPGMTGIEADAIARDYIASFGYGDAFGHSLGHGIGLEIHEGPNLSFKSPQKLEVGHVVTDEPGIY
LPGIGGVRIEDDLLITETGNEILIHSPKELIIL

Sequences:

>Translated_353_residues
MSKLTKIQETLGKEKIEAVLVTSEFNRRYVSGFTGTSGVALILPEKAYFVTDFRYTEQAAKQAEGYEIVQHTGPIFDTVE
DLLIKNDTKTLHFEADYVTVSEFKQMERVFNRQLIPLTGFFEEMRKVKTASELKAIRTACDIADAAFAHIIQFIKPGMAE
IEVSNELEFFMRRAGATSSSFDTIVASGVRSALPHGVASDKKIEVGDFVTMDYGCYYDGYCSDMTRTIAVGEPAEKLKEI
YQITLDAQLKVIDSLKPGMTGIEADAIARDYIASFGYGDAFGHSLGHGIGLEIHEGPNLSFKSPQKLEVGHVVTDEPGIY
LPGIGGVRIEDDLLITETGNEILIHSPKELIIL
>Mature_352_residues
SKLTKIQETLGKEKIEAVLVTSEFNRRYVSGFTGTSGVALILPEKAYFVTDFRYTEQAAKQAEGYEIVQHTGPIFDTVED
LLIKNDTKTLHFEADYVTVSEFKQMERVFNRQLIPLTGFFEEMRKVKTASELKAIRTACDIADAAFAHIIQFIKPGMAEI
EVSNELEFFMRRAGATSSSFDTIVASGVRSALPHGVASDKKIEVGDFVTMDYGCYYDGYCSDMTRTIAVGEPAEKLKEIY
QITLDAQLKVIDSLKPGMTGIEADAIARDYIASFGYGDAFGHSLGHGIGLEIHEGPNLSFKSPQKLEVGHVVTDEPGIYL
PGIGGVRIEDDLLITETGNEILIHSPKELIIL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI149589008, Length=328, Percent_Identity=27.4390243902439, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI260593665, Length=328, Percent_Identity=27.4390243902439, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI11559925, Length=261, Percent_Identity=28.735632183908, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI264681563, Length=227, Percent_Identity=32.5991189427313, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI264681565, Length=224, Percent_Identity=33.0357142857143, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI164420681, Length=244, Percent_Identity=26.2295081967213, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI93141226, Length=170, Percent_Identity=34.7058823529412, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1788728, Length=359, Percent_Identity=42.3398328690808, Blast_Score=285, Evalue=2e-78,
Organism=Escherichia coli, GI1789275, Length=270, Percent_Identity=31.4814814814815, Blast_Score=121, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17508215, Length=294, Percent_Identity=27.891156462585, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17509539, Length=232, Percent_Identity=26.2931034482759, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71996291, Length=249, Percent_Identity=24.4979919678715, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321118, Length=295, Percent_Identity=27.4576271186441, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320922, Length=272, Percent_Identity=25.3676470588235, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6322999, Length=176, Percent_Identity=34.6590909090909, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323273, Length=244, Percent_Identity=29.0983606557377, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI19920384, Length=280, Percent_Identity=30, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357079, Length=295, Percent_Identity=27.4576271186441, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21355531, Length=185, Percent_Identity=26.4864864864865, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI161078230, Length=243, Percent_Identity=30.4526748971193, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357287, Length=243, Percent_Identity=30.4526748971193, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 38987; Mature: 38856

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLTKIQETLGKEKIEAVLVTSEFNRRYVSGFTGTSGVALILPEKAYFVTDFRYTEQAA
CCHHHHHHHHHCHHHEEEEEEECCCCCCEECCCCCCCCEEEEECCCEEEEECHHHHHHHH
KQAEGYEIVQHTGPIFDTVEDLLIKNDTKTLHFEADYVTVSEFKQMERVFNRQLIPLTGF
HHCCCCEEEHHCCCHHHHHHHHHCCCCCCEEEEEECEEEHHHHHHHHHHHCCCCCCHHHH
FEEMRKVKTASELKAIRTACDIADAAFAHIIQFIKPGMAEIEVSNELEFFMRRAGATSSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCC
FDTIVASGVRSALPHGVASDKKIEVGDFVTMDYGCYYDGYCSDMTRTIAVGEPAEKLKEI
HHHHHHHHHHHHCCCCCCCCCEEECCCEEEECCCCCCCCHHHCCHHEEECCCHHHHHHHH
YQITLDAQLKVIDSLKPGMTGIEADAIARDYIASFGYGDAFGHSLGHGIGLEIHEGPNLS
HHHHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEECCCCCC
FKSPQKLEVGHVVTDEPGIYLPGIGGVRIEDDLLITETGNEILIHSPKELIIL
CCCCCCEEECEEEECCCCEEECCCCCEEEECCEEEEECCCEEEEECCCEEEEC
>Mature Secondary Structure 
SKLTKIQETLGKEKIEAVLVTSEFNRRYVSGFTGTSGVALILPEKAYFVTDFRYTEQAA
CHHHHHHHHHCHHHEEEEEEECCCCCCEECCCCCCCCEEEEECCCEEEEECHHHHHHHH
KQAEGYEIVQHTGPIFDTVEDLLIKNDTKTLHFEADYVTVSEFKQMERVFNRQLIPLTGF
HHCCCCEEEHHCCCHHHHHHHHHCCCCCCEEEEEECEEEHHHHHHHHHHHCCCCCCHHHH
FEEMRKVKTASELKAIRTACDIADAAFAHIIQFIKPGMAEIEVSNELEFFMRRAGATSSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCC
FDTIVASGVRSALPHGVASDKKIEVGDFVTMDYGCYYDGYCSDMTRTIAVGEPAEKLKEI
HHHHHHHHHHHHCCCCCCCCCEEECCCEEEECCCCCCCCHHHCCHHEEECCCHHHHHHHH
YQITLDAQLKVIDSLKPGMTGIEADAIARDYIASFGYGDAFGHSLGHGIGLEIHEGPNLS
HHHHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEECCCCCC
FKSPQKLEVGHVVTDEPGIYLPGIGGVRIEDDLLITETGNEILIHSPKELIIL
CCCCCCEEECEEEECCCCEEECCCCCEEEECCEEEEECCCEEEEECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]