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The map label for this gene is clpQ

Identifier: 226223881

GI number: 226223881

Start: 1288795

End: 1289334

Strand: Direct

Name: clpQ

Synonym: Lm4b_01288

Alternate gene names: 226223881

Gene position: 1288795-1289334 (Clockwise)

Preceding gene: 226223880

Following gene: 226223882

Centisome position: 44.25

GC content: 40.37

Gene sequence:

>540_bases
ATGGAATTGCACGCTACAACGATATTTGCGGTTCAACATGACGGAAAAGCAGCGATGGCTGGAGACGGTCAAGTGACGCT
TGGTGAATCGGTCGTAATGAAACATACCGCCAAAAAAGTTCGCCGTCTTTTTCATGATAAAGTAATTGCTGGATTTGCAG
GTTCAGTCGCAGATGCTTTTACTTTATTTGAAAAATTTGAAGCGAAATTGAATGAATATAATGGTAACTTAGAAAGAGCA
TCAGTCGAACTTGCTCAACAATGGCGCAGTGACAGTGTTTTAAGAAAATTAGAAGCTATGCTAATCGTGATGGACAAAGA
TACACTACTTTTAGTTTCAGGGACAGGAGAAGTTATTGAACCAGACGATGGTATTTTAGCTATCGGTTCTGGAGGTAATT
ATGCGCTAGCCGCTGGGCGAGCACTTAAAAGACATAATGGTGGTCAAATGGAAGCAAAGGATATCGCTCGTCATGCGCTA
GAAATCGCTTCTGAAATTTGTGTGTTTACAAATGATCATATTACAGTAGAAGAGCTTTGA

Upstream 100 bases:

>100_bases
TATCATCCACCCAGATCTATACGCACGTGACAAAAGAGCATTTAAAGTCTACTTATATGAAACATCATCCTAGGGCTTAA
ATTTGGAGGAGGTTAAAGAA

Downstream 100 bases:

>100_bases
AGGAGTGGTTAATTTGACAAATATAACGTTAATGAACCAGTTGACACCAAAGCAAATTGTTGAAAAACTGGATCAATATA
TTATTGGACAAACCGGAGCG

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MELHATTIFAVQHDGKAAMAGDGQVTLGESVVMKHTAKKVRRLFHDKVIAGFAGSVADAFTLFEKFEAKLNEYNGNLERA
SVELAQQWRSDSVLRKLEAMLIVMDKDTLLLVSGTGEVIEPDDGILAIGSGGNYALAAGRALKRHNGGQMEAKDIARHAL
EIASEICVFTNDHITVEEL

Sequences:

>Translated_179_residues
MELHATTIFAVQHDGKAAMAGDGQVTLGESVVMKHTAKKVRRLFHDKVIAGFAGSVADAFTLFEKFEAKLNEYNGNLERA
SVELAQQWRSDSVLRKLEAMLIVMDKDTLLLVSGTGEVIEPDDGILAIGSGGNYALAAGRALKRHNGGQMEAKDIARHAL
EIASEICVFTNDHITVEEL
>Mature_179_residues
MELHATTIFAVQHDGKAAMAGDGQVTLGESVVMKHTAKKVRRLFHDKVIAGFAGSVADAFTLFEKFEAKLNEYNGNLERA
SVELAQQWRSDSVLRKLEAMLIVMDKDTLLLVSGTGEVIEPDDGILAIGSGGNYALAAGRALKRHNGGQMEAKDIARHAL
EIASEICVFTNDHITVEEL

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery [H]

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790367, Length=174, Percent_Identity=54.5977011494253, Blast_Score=188, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022281
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: 3.4.25.-

Molecular weight: Translated: 19406; Mature: 19406

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELHATTIFAVQHDGKAAMAGDGQVTLGESVVMKHTAKKVRRLFHDKVIAGFAGSVADAF
CCEEEEEEEEEEECCCEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLFEKFEAKLNEYNGNLERASVELAQQWRSDSVLRKLEAMLIVMDKDTLLLVSGTGEVIE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHEEEEECCCEEEEEECCCCEEC
PDDGILAIGSGGNYALAAGRALKRHNGGQMEAKDIARHALEIASEICVFTNDHITVEEL
CCCCEEEEECCCCEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEECCEEEEEEC
>Mature Secondary Structure
MELHATTIFAVQHDGKAAMAGDGQVTLGESVVMKHTAKKVRRLFHDKVIAGFAGSVADAF
CCEEEEEEEEEEECCCEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLFEKFEAKLNEYNGNLERASVELAQQWRSDSVLRKLEAMLIVMDKDTLLLVSGTGEVIE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHEEEEECCCEEEEEECCCCEEC
PDDGILAIGSGGNYALAAGRALKRHNGGQMEAKDIARHALEIASEICVFTNDHITVEEL
CCCCEEEEECCCCEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]