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The map label for this gene is yqhD [H]

Identifier: 226223183

GI number: 226223183

Start: 595903

End: 597084

Strand: Direct

Name: yqhD [H]

Synonym: Lm4b_00580

Alternate gene names: 226223183

Gene position: 595903-597084 (Clockwise)

Preceding gene: 226223181

Following gene: 226223184

Centisome position: 20.46

GC content: 39.0

Gene sequence:

>1182_bases
ATGCAAAAAGAAATGTTGAACTTTGATTATTATAACCCTACGCATATTATTTTTGGTAAAAACCGTTTTAATGAATTAAA
TGAAGTGATTCCTCAAGATAAAAAAGTATTGATTTTGTATGGTGGTGGAAGTGTAGAACGTTTTGGAACTTTAGATAAAG
TAAAAACCGCTCTTAAATCACGCGAAGTAGGCGAATTTGGTGGCATTGAAGCGAATCCTACATACGAAACGTTAATTAAA
GCTATCCAACTAGTTAAAGAAGAAAACTATGACTTTTTACTTGCAGTCGGTGGAGGGTCAGTGATTGACGGAACAAAATT
CGTTGCAGCGGGAGCATTGTTCGACGGTGAACCGATGGATATTTTTGGTAGCGGAATTGGCGAAAAACGTCCGATTACAA
AAGCGCTTCCTTTTGGAACAGTACTAACACTTCCTGCAACTGGTTCTGAAATGAATAGCGGTGGTGTAATCACTTTTGTG
GAGAAGAAAGCGAAACTTGGCTTTGGTAGTGCTTATACTTATCCTGTTTTTTCTTTACTTGATCCAGAACTTACATACAC
ACTTCCAAAACGTCAACTTGCAAATGGTATTATGGACGCGTATGTGCATGTAATGGAACAATATATGACTTATCCAGTAG
GTGCTTTGCTGCAAGATCGTTATGCCGAAAGTCTACTACAAACTTTAATCGAAATTGGTCCAGATGTTATCAAAGAAGAT
AATCATGATTATAATACACGTGCTACTTTTATGTGGTCAGCTACAAATGCACTCAATGGAACATTATCCAGAGGCGTTCC
GCAAGATTGGGCAAGCCACAGTTTAGGTCACGAAATCACCGCACTTTATGGGATTGACCATGCACGTACGTTAGCAATAG
TTCTCCCGTCTCTTTTAAATGTTCGTCGCAGTGAAAAGCATGAGAAATTAGTCCAATATGCGGAACGAGTGTGGGGGATT
AAGAGTGGTAGTGATGAAGAAAAAATAGACGCTGCTATTCTCAAAACACGCGAGTTCTTTGAAAGCTTAGGAGCAGGAAC
TAGATTTAGTGATTATGGGCTTGGCGAGGAAGTAGTGGACTTACTCGTTGATCAATTAGAACGGCACGGTTTAACGAATA
TTTCAGAACGCGGCGACCAAACGTTAGAAGTATCTCGTCAAATTTATACAAATGCTTTATAA

Upstream 100 bases:

>100_bases
TATATAAATGGAAACTTTTGGCATAAGGTTTAAATTTTCTAAAAAAAGTGTATTATTAACTATGCTATGTAAATTTATAA
ACAGAAAGAAGGACGTTAAC

Downstream 100 bases:

>100_bases
TGGATAACGAAACTTTTGCGCAAATCATTAGAGAAGAAATTTGCTTACTTAAATAAAAATCAATAGAAAATGAAAGAGGG
CGAAATTTCTTGAGTACCAA

Product: NADH-dependent butanol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MQKEMLNFDYYNPTHIIFGKNRFNELNEVIPQDKKVLILYGGGSVERFGTLDKVKTALKSREVGEFGGIEANPTYETLIK
AIQLVKEENYDFLLAVGGGSVIDGTKFVAAGALFDGEPMDIFGSGIGEKRPITKALPFGTVLTLPATGSEMNSGGVITFV
EKKAKLGFGSAYTYPVFSLLDPELTYTLPKRQLANGIMDAYVHVMEQYMTYPVGALLQDRYAESLLQTLIEIGPDVIKED
NHDYNTRATFMWSATNALNGTLSRGVPQDWASHSLGHEITALYGIDHARTLAIVLPSLLNVRRSEKHEKLVQYAERVWGI
KSGSDEEKIDAAILKTREFFESLGAGTRFSDYGLGEEVVDLLVDQLERHGLTNISERGDQTLEVSRQIYTNAL

Sequences:

>Translated_393_residues
MQKEMLNFDYYNPTHIIFGKNRFNELNEVIPQDKKVLILYGGGSVERFGTLDKVKTALKSREVGEFGGIEANPTYETLIK
AIQLVKEENYDFLLAVGGGSVIDGTKFVAAGALFDGEPMDIFGSGIGEKRPITKALPFGTVLTLPATGSEMNSGGVITFV
EKKAKLGFGSAYTYPVFSLLDPELTYTLPKRQLANGIMDAYVHVMEQYMTYPVGALLQDRYAESLLQTLIEIGPDVIKED
NHDYNTRATFMWSATNALNGTLSRGVPQDWASHSLGHEITALYGIDHARTLAIVLPSLLNVRRSEKHEKLVQYAERVWGI
KSGSDEEKIDAAILKTREFFESLGAGTRFSDYGLGEEVVDLLVDQLERHGLTNISERGDQTLEVSRQIYTNAL
>Mature_393_residues
MQKEMLNFDYYNPTHIIFGKNRFNELNEVIPQDKKVLILYGGGSVERFGTLDKVKTALKSREVGEFGGIEANPTYETLIK
AIQLVKEENYDFLLAVGGGSVIDGTKFVAAGALFDGEPMDIFGSGIGEKRPITKALPFGTVLTLPATGSEMNSGGVITFV
EKKAKLGFGSAYTYPVFSLLDPELTYTLPKRQLANGIMDAYVHVMEQYMTYPVGALLQDRYAESLLQTLIEIGPDVIKED
NHDYNTRATFMWSATNALNGTLSRGVPQDWASHSLGHEITALYGIDHARTLAIVLPSLLNVRRSEKHEKLVQYAERVWGI
KSGSDEEKIDAAILKTREFFESLGAGTRFSDYGLGEEVVDLLVDQLERHGLTNISERGDQTLEVSRQIYTNAL

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=154, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789386, Length=390, Percent_Identity=56.4102564102564, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI48994951, Length=318, Percent_Identity=24.5283018867925, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082107, Length=284, Percent_Identity=26.4084507042254, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537053, Length=152, Percent_Identity=30.9210526315789, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321181, Length=339, Percent_Identity=25.0737463126844, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 43551; Mature: 43551

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKEMLNFDYYNPTHIIFGKNRFNELNEVIPQDKKVLILYGGGSVERFGTLDKVKTALKS
CCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCEEEEEECCCCCHHHCCHHHHHHHHHH
REVGEFGGIEANPTYETLIKAIQLVKEENYDFLLAVGGGSVIDGTKFVAAGALFDGEPMD
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEECCCHHHEECCCCCCCCHH
IFGSGIGEKRPITKALPFGTVLTLPATGSEMNSGGVITFVEKKAKLGFGSAYTYPVFSLL
HHCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCCCEEEEEECHHCCCCCCCCHHHHHHHC
DPELTYTLPKRQLANGIMDAYVHVMEQYMTYPVGALLQDRYAESLLQTLIEIGPDVIKED
CCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHCCC
NHDYNTRATFMWSATNALNGTLSRGVPQDWASHSLGHEITALYGIDHARTLAIVLPSLLN
CCCCCCEEEEEEECCCHHCCHHHCCCCHHHHHHCCCCHHHHEECCCHHHHHHHHHHHHHH
VRRSEKHEKLVQYAERVWGIKSGSDEEKIDAAILKTREFFESLGAGTRFSDYGLGEEVVD
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
LLVDQLERHGLTNISERGDQTLEVSRQIYTNAL
HHHHHHHHCCCCCHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQKEMLNFDYYNPTHIIFGKNRFNELNEVIPQDKKVLILYGGGSVERFGTLDKVKTALKS
CCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCEEEEEECCCCCHHHCCHHHHHHHHHH
REVGEFGGIEANPTYETLIKAIQLVKEENYDFLLAVGGGSVIDGTKFVAAGALFDGEPMD
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEECCCHHHEECCCCCCCCHH
IFGSGIGEKRPITKALPFGTVLTLPATGSEMNSGGVITFVEKKAKLGFGSAYTYPVFSLL
HHCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCCCEEEEEECHHCCCCCCCCHHHHHHHC
DPELTYTLPKRQLANGIMDAYVHVMEQYMTYPVGALLQDRYAESLLQTLIEIGPDVIKED
CCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHCCC
NHDYNTRATFMWSATNALNGTLSRGVPQDWASHSLGHEITALYGIDHARTLAIVLPSLLN
CCCCCCEEEEEEECCCHHCCHHHCCCCHHHHHHCCCCHHHHEECCCHHHHHHHHHHHHHH
VRRSEKHEKLVQYAERVWGIKSGSDEEKIDAAILKTREFFESLGAGTRFSDYGLGEEVVD
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
LLVDQLERHGLTNISERGDQTLEVSRQIYTNAL
HHHHHHHHCCCCCHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]