Click here to switch to the map view.

The map label for this gene is yclF [H]

Identifier: 226223184

GI number: 226223184

Start: 597174

End: 598652

Strand: Direct

Name: yclF [H]

Synonym: Lm4b_00581

Alternate gene names: 226223184

Gene position: 597174-598652 (Clockwise)

Preceding gene: 226223183

Following gene: 226223185

Centisome position: 20.5

GC content: 40.97

Gene sequence:

>1479_bases
TTGAGTACCAAGAAGGGAAAGACGTTTTTCGGCCATCCGCGCGGCCTAGCTACATTATTTAACACCGAATTTTGGGAGCG
ATTCTCCTATTACGGAATGCGTGCATTATTACTTTATTATATGTATACTGCAGTAGCAGATGGTGGACTTGGGTTTAGCC
AGTCTACCGCAACAGCAATTATGTCTATTTATGGTTCACTAGTATTTATGTCAGGAGTCATTGGTGGATGGTTCGCTGAC
CGTGTCTTGGGGGCACGACAGACCATTTTTTACGGTGGAGTCCTTATTATGGTGGGGCATATTGTACTAGCTTTACCAAA
TGGAGGAGCAGCGGCATTATTTGGTTCGATGGCATTTATAATTCTCGGAACTGGGCTACTTAAACCGAATGTTTCTAATG
TCGTTGGCGATTTATACCCAGCTGGCGATAATCGTCGTGATGCTGGTTTTAGTATCTTCTACATGGGGATTAACTTAGGT
GCATTTATTGCCCCGCCTATTGTTTCGGCAGTTTCTGATAATGCTGGAAGTTTCCATGCTGGTTTTGGTGTGGCAGCTGT
TGGTATGGCAATTGCACTTGTTGTTTATGTTCTTACAGGAAAACGTTACTTAAAAGACGCTGGCAAAAAAGCGCCAAATC
CGCTTCAAAGATCAGAAGCAAAAAGTCTTACATTCAAAATAATTGGCATTGTTTTAGGCATAGGATTATTAATTGCTGTT
TTAACACTAATTACAGGTAGCTTAACAATTGATACGATTATCCTTGCTGTAACGGTGATGGGCGTGGGGGTTCCACTCGC
TTACTTTATTATGATGATGACTAGCAAGAAAACCGAGGCGGACGAAAAATCACGATTAACTGCATACATACCGTTATTTT
TAATTGCTGTACTATTTTGGATGATTGAAGAACAAGGCTCGTCCACATTGGCGCTTTTCGCGGCAGAAAGAACGGATTTA
TCTATTTGGGGTATGAACTTAAATCCGGCCAATTTCCAGTCGCTTAACCCAGTGTTTGTTATTACACTTTCGCCAATTTT
CGCATGGATTTGGACGAAACTTGGTGATAGACAACCATCTACACCACGTAAATTTGCCCTTGGACTATTCTTCGCTGGTT
TATCTTTCGTTGTTATGATGCTTCCGGGTATCTTGCACGGAAACACAACAACGCTTGTAAGTCCGCTTTGGTTAGTACTA
AGTTTCTTCATCTGTATTTTCGGTGAAATGTTTATCTCACCAGTCGGATTATCTGCGACGACCAAACTAGCACCAAAAGC
TTTCGCATCTCAAACGATGAGCTTATGGTTCTTGTCAGATGCAATGGGGCAATCATTTAACGCACAATTAACACAATTAT
TTAATGCTGACACTGAAATTGCTTATTTCGGTATTACTGGTTTTGTAGCAATTGCTTTTGCGGTAGCATTATTCATTTTC
GCGCCATTCTTGAAAAAATATATGAAGGGCGTTCATTAA

Upstream 100 bases:

>100_bases
ATGCTTTATAATGGATAACGAAACTTTTGCGCAAATCATTAGAGAAGAAATTTGCTTACTTAAATAAAAATCAATAGAAA
ATGAAAGAGGGCGAAATTTC

Downstream 100 bases:

>100_bases
AGGAATTAAGCGCACTTTCTCCTTATTTGGAGGAAGTGTTTTTTTATGCTAGGAATAAATTAGTTTGCCATTAACTCCTA
AGATTGCTACTATTAAAGGG

Product: di-tripeptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MSTKKGKTFFGHPRGLATLFNTEFWERFSYYGMRALLLYYMYTAVADGGLGFSQSTATAIMSIYGSLVFMSGVIGGWFAD
RVLGARQTIFYGGVLIMVGHIVLALPNGGAAALFGSMAFIILGTGLLKPNVSNVVGDLYPAGDNRRDAGFSIFYMGINLG
AFIAPPIVSAVSDNAGSFHAGFGVAAVGMAIALVVYVLTGKRYLKDAGKKAPNPLQRSEAKSLTFKIIGIVLGIGLLIAV
LTLITGSLTIDTIILAVTVMGVGVPLAYFIMMMTSKKTEADEKSRLTAYIPLFLIAVLFWMIEEQGSSTLALFAAERTDL
SIWGMNLNPANFQSLNPVFVITLSPIFAWIWTKLGDRQPSTPRKFALGLFFAGLSFVVMMLPGILHGNTTTLVSPLWLVL
SFFICIFGEMFISPVGLSATTKLAPKAFASQTMSLWFLSDAMGQSFNAQLTQLFNADTEIAYFGITGFVAIAFAVALFIF
APFLKKYMKGVH

Sequences:

>Translated_492_residues
MSTKKGKTFFGHPRGLATLFNTEFWERFSYYGMRALLLYYMYTAVADGGLGFSQSTATAIMSIYGSLVFMSGVIGGWFAD
RVLGARQTIFYGGVLIMVGHIVLALPNGGAAALFGSMAFIILGTGLLKPNVSNVVGDLYPAGDNRRDAGFSIFYMGINLG
AFIAPPIVSAVSDNAGSFHAGFGVAAVGMAIALVVYVLTGKRYLKDAGKKAPNPLQRSEAKSLTFKIIGIVLGIGLLIAV
LTLITGSLTIDTIILAVTVMGVGVPLAYFIMMMTSKKTEADEKSRLTAYIPLFLIAVLFWMIEEQGSSTLALFAAERTDL
SIWGMNLNPANFQSLNPVFVITLSPIFAWIWTKLGDRQPSTPRKFALGLFFAGLSFVVMMLPGILHGNTTTLVSPLWLVL
SFFICIFGEMFISPVGLSATTKLAPKAFASQTMSLWFLSDAMGQSFNAQLTQLFNADTEIAYFGITGFVAIAFAVALFIF
APFLKKYMKGVH
>Mature_491_residues
STKKGKTFFGHPRGLATLFNTEFWERFSYYGMRALLLYYMYTAVADGGLGFSQSTATAIMSIYGSLVFMSGVIGGWFADR
VLGARQTIFYGGVLIMVGHIVLALPNGGAAALFGSMAFIILGTGLLKPNVSNVVGDLYPAGDNRRDAGFSIFYMGINLGA
FIAPPIVSAVSDNAGSFHAGFGVAAVGMAIALVVYVLTGKRYLKDAGKKAPNPLQRSEAKSLTFKIIGIVLGIGLLIAVL
TLITGSLTIDTIILAVTVMGVGVPLAYFIMMMTSKKTEADEKSRLTAYIPLFLIAVLFWMIEEQGSSTLALFAAERTDLS
IWGMNLNPANFQSLNPVFVITLSPIFAWIWTKLGDRQPSTPRKFALGLFFAGLSFVVMMLPGILHGNTTTLVSPLWLVLS
FFICIFGEMFISPVGLSATTKLAPKAFASQTMSLWFLSDAMGQSFNAQLTQLFNADTEIAYFGITGFVAIAFAVALFIFA
PFLKKYMKGVH

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=421, Percent_Identity=25.8907363420428, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI226371746, Length=380, Percent_Identity=27.1052631578947, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI226371748, Length=369, Percent_Identity=26.2872628726287, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1789911, Length=500, Percent_Identity=28.6, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1787922, Length=435, Percent_Identity=30.8045977011494, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1786927, Length=421, Percent_Identity=30.8788598574822, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1790572, Length=415, Percent_Identity=30.3614457831325, Blast_Score=182, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI71987453, Length=388, Percent_Identity=27.0618556701031, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17569141, Length=423, Percent_Identity=27.6595744680851, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17541704, Length=419, Percent_Identity=25.7756563245823, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28571098, Length=398, Percent_Identity=26.8844221105528, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24639585, Length=367, Percent_Identity=27.7929155313352, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24639583, Length=367, Percent_Identity=27.7929155313352, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24639581, Length=367, Percent_Identity=27.7929155313352, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28571102, Length=398, Percent_Identity=26.8844221105528, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28571100, Length=398, Percent_Identity=26.8844221105528, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53061; Mature: 52930

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKKGKTFFGHPRGLATLFNTEFWERFSYYGMRALLLYYMYTAVADGGLGFSQSTATAI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
MSIYGSLVFMSGVIGGWFADRVLGARQTIFYGGVLIMVGHIVLALPNGGAAALFGSMAFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHH
ILGTGLLKPNVSNVVGDLYPAGDNRRDAGFSIFYMGINLGAFIAPPIVSAVSDNAGSFHA
HHHCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCC
GFGVAAVGMAIALVVYVLTGKRYLKDAGKKAPNPLQRSEAKSLTFKIIGIVLGIGLLIAV
CHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LTLITGSLTIDTIILAVTVMGVGVPLAYFIMMMTSKKTEADEKSRLTAYIPLFLIAVLFW
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
MIEEQGSSTLALFAAERTDLSIWGMNLNPANFQSLNPVFVITLSPIFAWIWTKLGDRQPS
HHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCC
TPRKFALGLFFAGLSFVVMMLPGILHGNTTTLVSPLWLVLSFFICIFGEMFISPVGLSAT
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
TKLAPKAFASQTMSLWFLSDAMGQSFNAQLTQLFNADTEIAYFGITGFVAIAFAVALFIF
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHH
APFLKKYMKGVH
HHHHHHHHCCCC
>Mature Secondary Structure 
STKKGKTFFGHPRGLATLFNTEFWERFSYYGMRALLLYYMYTAVADGGLGFSQSTATAI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH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HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]