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The map label for this gene is licR [H]

Identifier: 226222933

GI number: 226222933

Start: 329896

End: 331767

Strand: Reverse

Name: licR [H]

Synonym: Lm4b_00325

Alternate gene names: 226222933

Gene position: 331767-329896 (Counterclockwise)

Preceding gene: 226222934

Following gene: 226222930

Centisome position: 11.39

GC content: 38.57

Gene sequence:

>1872_bases
ATGACTATTTCAGAAAGGCAACGTTCATTGTTAGAAAAGCTTAACGACAGCCAAAAGACAGTAACAGCAAAAGCACTTTC
AGAAATGTTAGGCGTTTCTTCCAAAACTGTGCGAAATGACATTATGCAAATTAACCAGTCATTTAGTTCCACAATCATCG
CATCAAAAGCTGGAAAAGGCTACTTTCTAACGCCAAACGAGCAGCTTTCACAAATAAATCTAACCAAAAATAGCGAAAAT
CTACATTTTGAATTATTACGCCATATTATCGAACAAGATCATACCAATTTCTATGATTTAGCGGATCAATTTTTCATTAG
CGAATCGACGTTAGCTCGTATTATTAAAGAACTCAACGCGGTTATCGCTGAAAAAGATACGTCGCTTTGTATTATTCGAA
AAAACAACGAACTACTAACCGAGGGCGGCGAAGAAGAAAAGCGCCGCATCTTCAATCTATTCCTCAATCAGGAAATCGAA
AACCATCAATTAAGCCTAGATAAATACGCCGATTACTTTGATTACTGCAATCTAAAGCAACTTTCCGAGCTTATTATTGC
CTACCACAAAAAGAACGATTTTTTTATGAATGATTTCTCGACGATTTCGTTCATTTTGCATATCGCCGTTTTAATTGAGC
GCATTAGTATGGGTAGCTATATAGAGCGCACTGCTTTACTCGAGCAAGATAAAACTAGTCTTGAAATGGCAGAGCATCTA
GCCGAAACGTTAGAAAATGAATTGCAAATCAATATTCCAACGCAAGAATTAAGCTATATCGCCCGGCTTTATTCCGGCAA
ACTAACGACAACTTCAACCATTGACGCACAAGTTTTTGGCAGCGTTGTCACTCGGCTCCTTGAAGCAGTGGACCAAAATT
TCCATATCGACTTTTCCGCTGATGAAAAAATAGCCACCTATCTAGTGGCCCATATTTCAGCCCTATACAAAAGAGCCAAT
CACAAACAATATTTAACCAACCCACTCACCGAAGAATTAAAAAATAAGTTTCCATTTATTTATAACGTCAGCGTCTATGC
TTCAGCCTTTATCCAAAAAGAGCTTGCGATCACTTTCCCAGATGACGAAATCGCTTATATCGCGCTACATTTTTTATCCG
CTTCGGAAACGATTAATCACGGTAAAAAAAGAAAAATCCTCTTGGTTTCACCGTACGGCGCAGGTAGCCAACGTTTAATT
CATAATCAACTTAAGAAAATTGCCGATTTTTCGATTGACTTGCTCGTTTCTCAATCTATTTTTGATATAAAGCAGTTCAC
CTTAGACAAAGAAATCCATTTAATTATCACCGCCGAACCATTAAACCTAACAACTGACATCCCAGTCTATCATTACGATT
TACTTTTAACAGAAACAGATTTGCAGAAAATCAAGCACATTTTAGAAACTAAGCCCAAAGCCGATTCGATTTCCAGAAAA
TTTTTCAAAAAAGAGCTGTTCTTCCCAAAACAAAACTTCAAATCAAAAGAAGAAGTAATTACGTTTCTTTGCGAACAGTT
AACTGCATTCGACTACTGCGACTCCGACTATGTTTCAAAAGTGTTTGAGCGCGAACAATTATCTAGCACCTGTTACGGCA
ACTACTACGCCATCCCGCACGCCATCCAGCGAAGCGCGAAGAAAAATGCCGTCGCCGTATGCGCACTTGATAAACCAATC
GACTGGGGAGGAAATCGCGTCAAACTCGTCCTATTACTCACTATGAAAGAAGAACGCGATAACTCTTTTGAAGAATTATT
CGGCCAACTCGTAACCATCTTAAACGAACGCAGCTTCGTCAAAAAACTAGCAAAACAAGAAGACTTCCAGCAATTTATCG
AACTTTGCGAACAAAAAACCCTAGATTCCTAA

Upstream 100 bases:

>100_bases
AATAACCACTTAAATAGAGATTGGGACAAAAAAACTCGTCTCTTTCTCTATTTGGTGTTGTATAATAACAATAGGTTAAG
GGAGAATTAGGGGGGATATA

Downstream 100 bases:

>100_bases
AAAATCTAGGGTTTTCTAATCCGATCAATTCCAAAAACAACAATCGGTAAGTAATTAAAAAAGAAACTAATCCGCTGACA
AAAACCAATTTTATCTAAAA

Product: transcriptional antiterminator (BglG family)

Products: NA

Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 623; Mature: 622

Protein sequence:

>623_residues
MTISERQRSLLEKLNDSQKTVTAKALSEMLGVSSKTVRNDIMQINQSFSSTIIASKAGKGYFLTPNEQLSQINLTKNSEN
LHFELLRHIIEQDHTNFYDLADQFFISESTLARIIKELNAVIAEKDTSLCIIRKNNELLTEGGEEEKRRIFNLFLNQEIE
NHQLSLDKYADYFDYCNLKQLSELIIAYHKKNDFFMNDFSTISFILHIAVLIERISMGSYIERTALLEQDKTSLEMAEHL
AETLENELQINIPTQELSYIARLYSGKLTTTSTIDAQVFGSVVTRLLEAVDQNFHIDFSADEKIATYLVAHISALYKRAN
HKQYLTNPLTEELKNKFPFIYNVSVYASAFIQKELAITFPDDEIAYIALHFLSASETINHGKKRKILLVSPYGAGSQRLI
HNQLKKIADFSIDLLVSQSIFDIKQFTLDKEIHLIITAEPLNLTTDIPVYHYDLLLTETDLQKIKHILETKPKADSISRK
FFKKELFFPKQNFKSKEEVITFLCEQLTAFDYCDSDYVSKVFEREQLSSTCYGNYYAIPHAIQRSAKKNAVAVCALDKPI
DWGGNRVKLVLLLTMKEERDNSFEELFGQLVTILNERSFVKKLAKQEDFQQFIELCEQKTLDS

Sequences:

>Translated_623_residues
MTISERQRSLLEKLNDSQKTVTAKALSEMLGVSSKTVRNDIMQINQSFSSTIIASKAGKGYFLTPNEQLSQINLTKNSEN
LHFELLRHIIEQDHTNFYDLADQFFISESTLARIIKELNAVIAEKDTSLCIIRKNNELLTEGGEEEKRRIFNLFLNQEIE
NHQLSLDKYADYFDYCNLKQLSELIIAYHKKNDFFMNDFSTISFILHIAVLIERISMGSYIERTALLEQDKTSLEMAEHL
AETLENELQINIPTQELSYIARLYSGKLTTTSTIDAQVFGSVVTRLLEAVDQNFHIDFSADEKIATYLVAHISALYKRAN
HKQYLTNPLTEELKNKFPFIYNVSVYASAFIQKELAITFPDDEIAYIALHFLSASETINHGKKRKILLVSPYGAGSQRLI
HNQLKKIADFSIDLLVSQSIFDIKQFTLDKEIHLIITAEPLNLTTDIPVYHYDLLLTETDLQKIKHILETKPKADSISRK
FFKKELFFPKQNFKSKEEVITFLCEQLTAFDYCDSDYVSKVFEREQLSSTCYGNYYAIPHAIQRSAKKNAVAVCALDKPI
DWGGNRVKLVLLLTMKEERDNSFEELFGQLVTILNERSFVKKLAKQEDFQQFIELCEQKTLDS
>Mature_622_residues
TISERQRSLLEKLNDSQKTVTAKALSEMLGVSSKTVRNDIMQINQSFSSTIIASKAGKGYFLTPNEQLSQINLTKNSENL
HFELLRHIIEQDHTNFYDLADQFFISESTLARIIKELNAVIAEKDTSLCIIRKNNELLTEGGEEEKRRIFNLFLNQEIEN
HQLSLDKYADYFDYCNLKQLSELIIAYHKKNDFFMNDFSTISFILHIAVLIERISMGSYIERTALLEQDKTSLEMAEHLA
ETLENELQINIPTQELSYIARLYSGKLTTTSTIDAQVFGSVVTRLLEAVDQNFHIDFSADEKIATYLVAHISALYKRANH
KQYLTNPLTEELKNKFPFIYNVSVYASAFIQKELAITFPDDEIAYIALHFLSASETINHGKKRKILLVSPYGAGSQRLIH
NQLKKIADFSIDLLVSQSIFDIKQFTLDKEIHLIITAEPLNLTTDIPVYHYDLLLTETDLQKIKHILETKPKADSISRKF
FKKELFFPKQNFKSKEEVITFLCEQLTAFDYCDSDYVSKVFEREQLSSTCYGNYYAIPHAIQRSAKKNAVAVCALDKPID
WGGNRVKLVLLLTMKEERDNSFEELFGQLVTILNERSFVKKLAKQEDFQQFIELCEQKTLDS

Specific function: Positive regulator of the licABCH operon [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788726, Length=143, Percent_Identity=28.6713286713287, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 71747; Mature: 71616

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISERQRSLLEKLNDSQKTVTAKALSEMLGVSSKTVRNDIMQINQSFSSTIIASKAGKG
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEECCCCC
YFLTPNEQLSQINLTKNSENLHFELLRHIIEQDHTNFYDLADQFFISESTLARIIKELNA
EEECCCHHHCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHH
VIAEKDTSLCIIRKNNELLTEGGEEEKRRIFNLFLNQEIENHQLSLDKYADYFDYCNLKQ
HHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHH
LSELIIAYHKKNDFFMNDFSTISFILHIAVLIERISMGSYIERTALLEQDKTSLEMAEHL
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHH
AETLENELQINIPTQELSYIARLYSGKLTTTSTIDAQVFGSVVTRLLEAVDQNFHIDFSA
HHHHCCCEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCC
DEKIATYLVAHISALYKRANHKQYLTNPLTEELKNKFPFIYNVSVYASAFIQKELAITFP
CHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHCCCEEEEHHHHHHHHHHHCEEEECC
DDEIAYIALHFLSASETINHGKKRKILLVSPYGAGSQRLIHNQLKKIADFSIDLLVSQSI
CCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
FDIKQFTLDKEIHLIITAEPLNLTTDIPVYHYDLLLTETDLQKIKHILETKPKADSISRK
HHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHCCCCHHHHHHH
FFKKELFFPKQNFKSKEEVITFLCEQLTAFDYCDSDYVSKVFEREQLSSTCYGNYYAIPH
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEECHH
AIQRSAKKNAVAVCALDKPIDWGGNRVKLVLLLTMKEERDNSFEELFGQLVTILNERSFV
HHHHHCCCCCEEEEEECCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
KKLAKQEDFQQFIELCEQKTLDS
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TISERQRSLLEKLNDSQKTVTAKALSEMLGVSSKTVRNDIMQINQSFSSTIIASKAGKG
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEECCCCC
YFLTPNEQLSQINLTKNSENLHFELLRHIIEQDHTNFYDLADQFFISESTLARIIKELNA
EEECCCHHHCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHH
VIAEKDTSLCIIRKNNELLTEGGEEEKRRIFNLFLNQEIENHQLSLDKYADYFDYCNLKQ
HHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHH
LSELIIAYHKKNDFFMNDFSTISFILHIAVLIERISMGSYIERTALLEQDKTSLEMAEHL
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHH
AETLENELQINIPTQELSYIARLYSGKLTTTSTIDAQVFGSVVTRLLEAVDQNFHIDFSA
HHHHCCCEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCC
DEKIATYLVAHISALYKRANHKQYLTNPLTEELKNKFPFIYNVSVYASAFIQKELAITFP
CHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHCCCEEEEHHHHHHHHHHHCEEEECC
DDEIAYIALHFLSASETINHGKKRKILLVSPYGAGSQRLIHNQLKKIADFSIDLLVSQSI
CCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
FDIKQFTLDKEIHLIITAEPLNLTTDIPVYHYDLLLTETDLQKIKHILETKPKADSISRK
HHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHCCCCHHHHHHH
FFKKELFFPKQNFKSKEEVITFLCEQLTAFDYCDSDYVSKVFEREQLSSTCYGNYYAIPH
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEECHH
AIQRSAKKNAVAVCALDKPIDWGGNRVKLVLLLTMKEERDNSFEELFGQLVTILNERSFV
HHHHHCCCCCEEEEEECCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
KKLAKQEDFQQFIELCEQKTLDS
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377; 10438772 [H]