| Definition | Brucella melitensis ATCC 23457 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_012441 |
| Length | 2,125,701 |
Click here to switch to the map view.
The map label for this gene is fabG [H]
Identifier: 225853472
GI number: 225853472
Start: 1981633
End: 1982397
Strand: Reverse
Name: fabG [H]
Synonym: BMEA_A2100
Alternate gene names: 225853472
Gene position: 1982397-1981633 (Counterclockwise)
Preceding gene: 225853474
Following gene: 225853470
Centisome position: 93.26
GC content: 59.22
Gene sequence:
>765_bases ATGGGTGAATTCGCGGTCGTGACGGGCGGCAGCACCGGCATTGGAAGACATCTGGTTTCGGCCTTTGCAGATGCAGGTTA TGCGGTTGCTTTCAGCTATCGGCATGATGATGATGCCGCACAATCACTTGTCGAGGCCATTGAGGAGGCGGGCGGTCAGG CGCTTGGGCTTGGCTGCGATGTCGGCAGGCGGGCCGAAGTGGAAGCCTTCTTCGACGAGGCTTGCGACTGGTTTGGCGAT GCGCCGGATGTGCTGGTCAACAATGCGGGCATCCAGACCTGGGCGCCCTTGCTGGAACTTTCCGAAGAGGGGTGGGACGA TGTTATCCGCACCAATCTGAAAGGCTGCTTTCTCAACACGCAGGCTGCCGCAAAGCGCATGGTGGAAGCCGACAAGGGCG GCGCCATCGTCAATATCGGTTCCGGCTGCAACAAGCTGGCTTTTCCGAAACTGGTTTCCTATACGGCGTCGAAGGGTGGC ATAGAACAATTGACCAAGGCTTCTGCTGTGGAGCTTGGCCCCCACGGCATCCGTGTCAATTGCGTTGCGCCCGGTGCTAT CCTCAATGAGCGCACCGCGCAGGAACAACCTGATTATGCGCAGAGCTGGGCTCCGATCACGCCGCTACGCCGGGTTGGTG TACCGGAGGATATTTCGGGGCCTGTTCTGTTCCTCGTTTCCGATGAAGCCCGGTTCGTGACCGGCCAGACATTATGGGTT GATGGCGGGCTCTTCTCGCAGGCCAACTGGCCTTATGACGGGTGA
Upstream 100 bases:
>100_bases TCCTCGTCCTTACCTGAAAGCTATTTTCCTTTTTGCCGGTTTACCAGTGCGGAAAACCGGTTAAGTTTATCGTCTGGAAC AGTTCTGGGAGTGAGCTTTC
Downstream 100 bases:
>100_bases TGGTTCGGTGGTGATCCCGACAGGAATCGAACCTGTGACCTACAGATTAGGAATCTGTCGCTCTATCCTACTGAGCTACG GGACCAACCGATGCGCACTC
Product: glucose 1-dehydrogenase 2
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 254; Mature: 253
Protein sequence:
>254_residues MGEFAVVTGGSTGIGRHLVSAFADAGYAVAFSYRHDDDAAQSLVEAIEEAGGQALGLGCDVGRRAEVEAFFDEACDWFGD APDVLVNNAGIQTWAPLLELSEEGWDDVIRTNLKGCFLNTQAAAKRMVEADKGGAIVNIGSGCNKLAFPKLVSYTASKGG IEQLTKASAVELGPHGIRVNCVAPGAILNERTAQEQPDYAQSWAPITPLRRVGVPEDISGPVLFLVSDEARFVTGQTLWV DGGLFSQANWPYDG
Sequences:
>Translated_254_residues MGEFAVVTGGSTGIGRHLVSAFADAGYAVAFSYRHDDDAAQSLVEAIEEAGGQALGLGCDVGRRAEVEAFFDEACDWFGD APDVLVNNAGIQTWAPLLELSEEGWDDVIRTNLKGCFLNTQAAAKRMVEADKGGAIVNIGSGCNKLAFPKLVSYTASKGG IEQLTKASAVELGPHGIRVNCVAPGAILNERTAQEQPDYAQSWAPITPLRRVGVPEDISGPVLFLVSDEARFVTGQTLWV DGGLFSQANWPYDG >Mature_253_residues GEFAVVTGGSTGIGRHLVSAFADAGYAVAFSYRHDDDAAQSLVEAIEEAGGQALGLGCDVGRRAEVEAFFDEACDWFGDA PDVLVNNAGIQTWAPLLELSEEGWDDVIRTNLKGCFLNTQAAAKRMVEADKGGAIVNIGSGCNKLAFPKLVSYTASKGGI EQLTKASAVELGPHGIRVNCVAPGAILNERTAQEQPDYAQSWAPITPLRRVGVPEDISGPVLFLVSDEARFVTGQTLWVD GGLFSQANWPYDG
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=269, Percent_Identity=34.5724907063197, Blast_Score=141, Evalue=7e-34, Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=36.5461847389558, Blast_Score=135, Evalue=4e-32, Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=33.0645161290323, Blast_Score=117, Evalue=8e-27, Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=34.0163934426229, Blast_Score=114, Evalue=6e-26, Organism=Homo sapiens, GI7705925, Length=255, Percent_Identity=30.9803921568627, Blast_Score=112, Evalue=4e-25, Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=31.4741035856574, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=32.3275862068966, Blast_Score=91, Evalue=7e-19, Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=29.6296296296296, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=29.7959183673469, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI66933014, Length=191, Percent_Identity=29.8429319371728, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI209862901, Length=206, Percent_Identity=30.5825242718447, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI19923983, Length=206, Percent_Identity=30.5825242718447, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI4503301, Length=211, Percent_Identity=26.5402843601896, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=30.3867403314917, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI33667109, Length=186, Percent_Identity=30.6451612903226, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI4504505, Length=193, Percent_Identity=32.6424870466321, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI31542939, Length=242, Percent_Identity=26.4462809917355, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI109715829, Length=240, Percent_Identity=26.25, Blast_Score=70, Evalue=3e-12, Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=34.7826086956522, Blast_Score=147, Evalue=7e-37, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=39.1836734693878, Blast_Score=146, Evalue=1e-36, Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=36.144578313253, Blast_Score=139, Evalue=1e-34, Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=35.7723577235772, Blast_Score=132, Evalue=2e-32, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=34.0163934426229, Blast_Score=129, Evalue=2e-31, Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=35.7429718875502, Blast_Score=118, Evalue=5e-28, Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=32.6530612244898, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=32.3770491803279, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=31.1740890688259, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=31.8725099601594, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=30.46875, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=29.4354838709677, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787526, Length=241, Percent_Identity=27.3858921161826, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=29.5698924731183, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1787545, Length=256, Percent_Identity=26.171875, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=36.8852459016393, Blast_Score=132, Evalue=2e-31, Organism=Caenorhabditis elegans, GI17536025, Length=247, Percent_Identity=31.5789473684211, Blast_Score=122, Evalue=2e-28, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=34.6938775510204, Blast_Score=121, Evalue=3e-28, Organism=Caenorhabditis elegans, GI17536651, Length=247, Percent_Identity=31.1740890688259, Blast_Score=120, Evalue=9e-28, Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=30.241935483871, Blast_Score=113, Evalue=8e-26, Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=30.7086614173228, Blast_Score=110, Evalue=6e-25, Organism=Caenorhabditis elegans, GI115534694, Length=241, Percent_Identity=31.5352697095436, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=28.4552845528455, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=28.996282527881, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17561272, Length=231, Percent_Identity=29.4372294372294, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=28.4584980237154, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=27.5471698113208, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=26.6409266409266, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=29.5880149812734, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=29.2134831460674, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562908, Length=259, Percent_Identity=26.6409266409266, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=26.9230769230769, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=27.2030651340996, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=26.4925373134328, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=27.1317829457364, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=28.2442748091603, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17562904, Length=256, Percent_Identity=27.34375, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=30.3030303030303, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=25.7692307692308, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17563726, Length=275, Percent_Identity=28, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=26.8199233716475, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17555612, Length=205, Percent_Identity=29.2682926829268, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=26.4367816091954, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17508651, Length=248, Percent_Identity=24.1935483870968, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=27.3764258555133, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI71997099, Length=205, Percent_Identity=28.780487804878, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17564282, Length=186, Percent_Identity=28.494623655914, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI71982365, Length=192, Percent_Identity=28.6458333333333, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=29.6875, Blast_Score=91, Evalue=2e-19, Organism=Saccharomyces cerevisiae, GI6322861, Length=253, Percent_Identity=27.6679841897233, Blast_Score=72, Evalue=7e-14, Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=37.1428571428571, Blast_Score=135, Evalue=3e-32, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=33.7349397590361, Blast_Score=122, Evalue=2e-28, Organism=Drosophila melanogaster, GI28571526, Length=244, Percent_Identity=33.6065573770492, Blast_Score=121, Evalue=5e-28, Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=32.1285140562249, Blast_Score=120, Evalue=7e-28, Organism=Drosophila melanogaster, GI21357041, Length=244, Percent_Identity=32.7868852459016, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=7e-25, Organism=Drosophila melanogaster, GI24644337, Length=248, Percent_Identity=31.0483870967742, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=32.3886639676113, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI24584752, Length=193, Percent_Identity=29.5336787564767, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI116007236, Length=236, Percent_Identity=27.1186440677966, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24641232, Length=197, Percent_Identity=31.4720812182741, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI18859837, Length=193, Percent_Identity=33.160621761658, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI281364892, Length=187, Percent_Identity=31.5508021390374, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI116007238, Length=207, Percent_Identity=28.5024154589372, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI161076933, Length=191, Percent_Identity=28.7958115183246, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24584748, Length=191, Percent_Identity=28.7958115183246, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI221510726, Length=144, Percent_Identity=31.9444444444444, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26893; Mature: 26762
Theoretical pI: Translated: 4.22; Mature: 4.22
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 0.4 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGEFAVVTGGSTGIGRHLVSAFADAGYAVAFSYRHDDDAAQSLVEAIEEAGGQALGLGCD CCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEECCC VGRRAEVEAFFDEACDWFGDAPDVLVNNAGIQTWAPLLELSEEGWDDVIRTNLKGCFLNT CCCCCHHHHHHHHHHHHCCCCCHHEEECCCHHHHHHHHHHHHCCHHHHHHHCCCCEEECH QAAAKRMVEADKGGAIVNIGSGCNKLAFPKLVSYTASKGGIEQLTKASAVELGPHGIRVN HHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCEEEE CVAPGAILNERTAQEQPDYAQSWAPITPLRRVGVPEDISGPVLFLVSDEARFVTGQTLWV EECCCHHHCCCCCCCCCCHHHCCCCCCHHHHCCCCCCCCCCEEEEEECCCEEEECCEEEE DGGLFSQANWPYDG ECCEECCCCCCCCC >Mature Secondary Structure GEFAVVTGGSTGIGRHLVSAFADAGYAVAFSYRHDDDAAQSLVEAIEEAGGQALGLGCD CCEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEECCC VGRRAEVEAFFDEACDWFGDAPDVLVNNAGIQTWAPLLELSEEGWDDVIRTNLKGCFLNT CCCCCHHHHHHHHHHHHCCCCCHHEEECCCHHHHHHHHHHHHCCHHHHHHHCCCCEEECH QAAAKRMVEADKGGAIVNIGSGCNKLAFPKLVSYTASKGGIEQLTKASAVELGPHGIRVN HHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCEEEE CVAPGAILNERTAQEQPDYAQSWAPITPLRRVGVPEDISGPVLFLVSDEARFVTGQTLWV EECCCHHHCCCCCCCCCCHHHCCCCCCHHHHCCCCCCCCCCEEEEEECCCEEEECCEEEE DGGLFSQANWPYDG ECCEECCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA