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The map label for this gene is birA [H]

Identifier: 225852332

GI number: 225852332

Start: 815611

End: 816408

Strand: Direct

Name: birA [H]

Synonym: BMEA_A0858

Alternate gene names: 225852332

Gene position: 815611-816408 (Clockwise)

Preceding gene: 225852331

Following gene: 225852333

Centisome position: 38.37

GC content: 58.52

Gene sequence:

>798_bases
ATGAGTTTTGCGCTTTCGCCGGTGGCGGCAAATGAGGGCTACCGTCTCGAAACTTTCGAGGCGGTAGGTTCCACCAATGC
GGTTGCTCTGGAACGGGCGGCTGGCGGTGATCCGGGCAAGCTCTGGCTTGTTACGAAAAAACAGGAAAGCGGCCGCGGAA
GACGGGGCCGCGCCTGGTCTACGCCGGAAGGCAATCTTGCCTCCACGCTGCTTCTGGTCGAATCCTATGAAATGAAGACG
GCAGCGACGCTTGGTTTCGTCGCGGGCCTGTCGCTTGCCGATGCGCTTGATGCGGTCTTTGCCGCAACCGGGCCTGCGGT
GCCGCCGACAATCGGCCTCAAATGGCCAAATGACGTTCTGGTCAATGGCGCCAAACTCACCGGCATCCTGCTGGAATCTT
CCATTCTGGCAAAGAATTTGTTTGCCGTTGCCATCGGCATCGGGACCAATGTGGTCGCCTTTCCGGACGACCCGCCTTAT
CCGGCAACCTCATTGCGGGCGCTCGGCAGCAAATGTGATGCTGAAACCCTGTTCGCTGCGCTGTCGGATGCGTGGTCGGT
CAACTATCGTGTCTGGAACGAGGGGCGTTGTCTCGACGATATTCGCAAGCGTTGGCTTAAGCGCGCGCATGGCCTTGGCC
AGCACGTTACCATGCAGGTTGAAGGCCGCGTTGTTGAAGGTCGTTTCGAGACGATTGACGAGGCTTGTCGCTTTGTTATT
CGCGAGGATGAAGGTTCGCGGGTCGCGGTAACGGCGGGCGATGTCTATTTCGGGACGGCTGCAACAATACGCAAATAA

Upstream 100 bases:

>100_bases
TTCGTGCTTTTCTATGTCTTCCTTGCTGGCCCGATTGGCGGATATGCCGAAGCCGCAGCCAGGACGTTTTTCTAATCAAA
GCTTGGGGGCGGAAGCTGAG

Downstream 100 bases:

>100_bases
TTTCGTTGTCTTGTATTGCAGGGGTTGCAACAGGGTAGCTTTAGGTCCAGTTGAAGCGACAAGACTAGAGCGCATCCCGA
AAAGTGCGAAACAGTTTTGC

Product: biotin--acetyl-CoA-carboxylase ligase

Products: NA

Alternate protein names: Biotin--protein ligase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSFALSPVAANEGYRLETFEAVGSTNAVALERAAGGDPGKLWLVTKKQESGRGRRGRAWSTPEGNLASTLLLVESYEMKT
AATLGFVAGLSLADALDAVFAATGPAVPPTIGLKWPNDVLVNGAKLTGILLESSILAKNLFAVAIGIGTNVVAFPDDPPY
PATSLRALGSKCDAETLFAALSDAWSVNYRVWNEGRCLDDIRKRWLKRAHGLGQHVTMQVEGRVVEGRFETIDEACRFVI
REDEGSRVAVTAGDVYFGTAATIRK

Sequences:

>Translated_265_residues
MSFALSPVAANEGYRLETFEAVGSTNAVALERAAGGDPGKLWLVTKKQESGRGRRGRAWSTPEGNLASTLLLVESYEMKT
AATLGFVAGLSLADALDAVFAATGPAVPPTIGLKWPNDVLVNGAKLTGILLESSILAKNLFAVAIGIGTNVVAFPDDPPY
PATSLRALGSKCDAETLFAALSDAWSVNYRVWNEGRCLDDIRKRWLKRAHGLGQHVTMQVEGRVVEGRFETIDEACRFVI
REDEGSRVAVTAGDVYFGTAATIRK
>Mature_264_residues
SFALSPVAANEGYRLETFEAVGSTNAVALERAAGGDPGKLWLVTKKQESGRGRRGRAWSTPEGNLASTLLLVESYEMKTA
ATLGFVAGLSLADALDAVFAATGPAVPPTIGLKWPNDVLVNGAKLTGILLESSILAKNLFAVAIGIGTNVVAFPDDPPYP
ATSLRALGSKCDAETLFAALSDAWSVNYRVWNEGRCLDDIRKRWLKRAHGLGQHVTMQVEGRVVEGRFETIDEACRFVIR
EDEGSRVAVTAGDVYFGTAATIRK

Specific function: Activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins [H]

COG id: COG0340

COG function: function code H; Biotin-(acetyl-CoA carboxylase) ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the biotin--protein ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004408
- InterPro:   IPR003142
- InterPro:   IPR004143 [H]

Pfam domain/function: PF02237 BPL_C; PF03099 BPL_LipA_LipB [H]

EC number: =6.3.4.15 [H]

Molecular weight: Translated: 28314; Mature: 28183

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFALSPVAANEGYRLETFEAVGSTNAVALERAAGGDPGKLWLVTKKQESGRGRRGRAWS
CCEECCCEECCCCCEEEEEHHCCCCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCC
TPEGNLASTLLLVESYEMKTAATLGFVAGLSLADALDAVFAATGPAVPPTIGLKWPNDVL
CCCCCHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHE
VNGAKLTGILLESSILAKNLFAVAIGIGTNVVAFPDDPPYPATSLRALGSKCDAETLFAA
ECCCEEEEEEHHHHHHHHHEEEEEEECCCCEEECCCCCCCCHHHHHHHCCCCCHHHHHHH
LSDAWSVNYRVWNEGRCLDDIRKRWLKRAHGLGQHVTMQVEGRVVEGRFETIDEACRFVI
HHCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCEEECCHHHHHHHHHHEEE
REDEGSRVAVTAGDVYFGTAATIRK
EECCCCEEEEEECCEEECCHHCCCC
>Mature Secondary Structure 
SFALSPVAANEGYRLETFEAVGSTNAVALERAAGGDPGKLWLVTKKQESGRGRRGRAWS
CEECCCEECCCCCEEEEEHHCCCCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCC
TPEGNLASTLLLVESYEMKTAATLGFVAGLSLADALDAVFAATGPAVPPTIGLKWPNDVL
CCCCCHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHE
VNGAKLTGILLESSILAKNLFAVAIGIGTNVVAFPDDPPYPATSLRALGSKCDAETLFAA
ECCCEEEEEEHHHHHHHHHEEEEEEECCCCEEECCCCCCCCHHHHHHHCCCCCHHHHHHH
LSDAWSVNYRVWNEGRCLDDIRKRWLKRAHGLGQHVTMQVEGRVVEGRFETIDEACRFVI
HHCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCEEECCHHHHHHHHHHEEE
REDEGSRVAVTAGDVYFGTAATIRK
EECCCCEEEEEECCEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8422400 [H]